JPS50157342A - - Google Patents

Info

Publication number
JPS50157342A
JPS50157342A JP50025688A JP2568875A JPS50157342A JP S50157342 A JPS50157342 A JP S50157342A JP 50025688 A JP50025688 A JP 50025688A JP 2568875 A JP2568875 A JP 2568875A JP S50157342 A JPS50157342 A JP S50157342A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50025688A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS50157342A publication Critical patent/JPS50157342A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP50025688A 1974-03-04 1975-03-04 Pending JPS50157342A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44780474A 1974-03-04 1974-03-04
US05/545,074 US3974157A (en) 1974-03-04 1975-01-29 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters

Publications (1)

Publication Number Publication Date
JPS50157342A true JPS50157342A (ja) 1975-12-19

Family

ID=27035098

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50025688A Pending JPS50157342A (ja) 1974-03-04 1975-03-04

Country Status (13)

Country Link
US (1) US3974157A (ja)
JP (1) JPS50157342A (ja)
BE (1) BE826260A (ja)
CH (4) CH621329A5 (ja)
DK (2) DK143698C (ja)
FI (1) FI60205C (ja)
FR (1) FR2262974B1 (ja)
GB (1) GB1474004A (ja)
IE (1) IE40733B1 (ja)
LU (1) LU71964A1 (ja)
NL (1) NL7502450A (ja)
NO (1) NO140100C (ja)
SE (2) SE7502407L (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57122041A (en) * 1981-01-21 1982-07-29 Suntory Ltd Phenylclohexane derivative
JP2003519209A (ja) * 2000-01-05 2003-06-17 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング アミノメチル−フェニル−シクロヘキサノン誘導体
JP2010529045A (ja) * 2007-05-31 2010-08-26 セプラコール インク． モノアミン再取り込み阻害薬としてのフェニル置換シクロアルキルアミン

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115589A (en) * 1977-05-17 1978-09-19 The Upjohn Company Compounds, compositions and method of use
US4306097A (en) * 1977-09-13 1981-12-15 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents
US4366172A (en) * 1977-09-29 1982-12-28 The Upjohn Company 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use
FR2472559A1 (fr) * 1979-12-31 1981-07-03 Cerm Cent Europ Rech Mauvernay Derives du 1-aminomethyl 2-phenoxy cyclohexanol, procede d'obtention, application en therapeutique et compositions les contenant
US4391827A (en) * 1980-09-08 1983-07-05 Pfizer Inc. 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor
US4831059A (en) * 1980-09-19 1989-05-16 Pfizer Inc. Producing analgesia with pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes derivatives
US4486609A (en) * 1981-03-16 1984-12-04 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4933475A (en) * 1980-09-19 1990-06-12 Pfizer, Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4593131A (en) * 1980-09-19 1986-06-03 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4835192A (en) * 1980-09-19 1989-05-30 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4285867A (en) * 1980-09-19 1981-08-25 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4921994A (en) * 1980-09-19 1990-05-01 Pfizer Inc. Pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes and derivatives thereof
US4371720A (en) * 1980-09-19 1983-02-01 Pfizer Inc. 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives
US4331602A (en) * 1980-09-19 1982-05-25 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted]phenyl)naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4739079A (en) * 1980-09-19 1988-04-19 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4847414A (en) * 1981-10-19 1989-07-11 Hoechst-Roussel Pharmaceuticals, Inc. 2'-substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and intermediates thereof
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
DE3467341D1 (en) * 1983-08-19 1987-12-17 Pennwalt Corp Cyclohexane carboxylic acids and derivatives thereof as antidysrhythmic agents
GB8405112D0 (en) * 1984-02-28 1984-04-04 Akzo Nv Anti-arrhythmic amino-alcohols
US4760146A (en) * 1986-02-18 1988-07-26 Pennwalt Corporation Cyclohexene carboxylic esters and amides as antidysrhythmic agents
US5248830A (en) * 1989-08-24 1993-09-28 Rhone-Poulenc Rorer Pharmaceuticals Inc. Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydro-pyran-2-ones
AU2023292A (en) * 1991-02-11 1992-09-15 Rhone-Poulenc Rorer International (Holdings) Inc. Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydropyran-2-ones
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) * 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
DE10048714A1 (de) * 2000-09-30 2002-04-11 Gruenenthal Gmbh 5-Amino-1-penlen-3-ol-Derivate
US10968209B2 (en) 2016-05-19 2021-04-06 Glaxosmithkline Intellectual Property (No.2) Limited TRPV4 antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2586512A (en) * 1948-09-15 1952-02-19 Searle & Co Cyclohexyl-amino-alcohols
US2680115A (en) * 1949-01-28 1954-06-01 Maurice L Tainter Substituted tertiary-aminoalkyl carbinols
US2656386A (en) * 1951-02-24 1953-10-20 Upjohn Co Aminoethylhydrocarbonoxycyclohexenes
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57122041A (en) * 1981-01-21 1982-07-29 Suntory Ltd Phenylclohexane derivative
JPH0250894B2 (ja) * 1981-01-21 1990-11-05 Suntory Ltd
JP2003519209A (ja) * 2000-01-05 2003-06-17 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング アミノメチル−フェニル−シクロヘキサノン誘導体
JP2010529045A (ja) * 2007-05-31 2010-08-26 セプラコール インク． モノアミン再取り込み阻害薬としてのフェニル置換シクロアルキルアミン
US9586888B2 (en) 2007-05-31 2017-03-07 Sunovion Pharmaceuticals Inc. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors

Also Published As

Publication number Publication date
CH621329A5 (ja) 1981-01-30
DK143698B (da) 1981-09-28
FI60205C (fi) 1981-12-10
FI60205B (fi) 1981-08-31
CH619207A5 (en) 1980-09-15
BE826260A (nl) 1975-06-30
FI750601A (ja) 1975-09-05
NO140100C (no) 1979-07-04
DK328479A (da) 1979-08-03
CH615413A5 (en) 1980-01-31
CH617921A5 (en) 1980-06-30
NL7502450A (nl) 1975-09-08
SE8203051L (sv) 1982-05-14
GB1474004A (en) 1977-05-18
FR2262974B1 (ja) 1980-01-25
US3974157A (en) 1976-08-10
NO140100B (no) 1979-03-26
NO750706L (ja) 1975-09-05
DK83575A (ja) 1975-09-05
SE7502407L (ja) 1975-09-05
FR2262974A1 (ja) 1975-10-03
IE40733B1 (en) 1979-08-01
IE40733L (en) 1975-09-04
LU71964A1 (ja) 1975-08-20
DK143698C (da) 1982-03-08
AU7877375A (en) 1976-09-09

Similar Documents

Publication Publication Date Title
FI750166A (ja)
FR2262974A1 (ja)
DK675A (ja)
AU495930B2 (ja)
AU480208A (ja)
AU480471A (ja)
AU480758A (ja)
AU480863A (ja)
BG19768A1 (ja)
BG19847A1 (ja)
BG19987A1 (ja)
BG20440A1 (ja)
BG20446A1 (ja)
BG20451A1 (ja)
BG20462A1 (ja)
BG20638A1 (ja)
BG20854A1 (ja)
BG20883A1 (ja)
BG20885A1 (ja)
BG20950A1 (ja)
BG21129A1 (ja)
BG21307A1 (ja)
BG21351A1 (ja)
BG21352A1 (ja)
BG21526A1 (ja)