DK143698C - Analogifremgangsmaade til fremstilling af 1-aminoalkyl-2-aryl-cyclohexylalkoholer og estere eller salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 1-aminoalkyl-2-aryl-cyclohexylalkoholer og estere eller salte deraf

Info

Publication number
DK143698C
DK143698C DK83575A DK83575A DK143698C DK 143698 C DK143698 C DK 143698C DK 83575 A DK83575 A DK 83575A DK 83575 A DK83575 A DK 83575A DK 143698 C DK143698 C DK 143698C
Authority
DK
Denmark
Prior art keywords
aminoalkyl
analogue
aryl
esters
salts
Prior art date
Application number
DK83575A
Other languages
English (en)
Other versions
DK143698B (da
DK83575A (da
Inventor
B V Shetty
T L Thomas
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of DK83575A publication Critical patent/DK83575A/da
Publication of DK143698B publication Critical patent/DK143698B/da
Application granted granted Critical
Publication of DK143698C publication Critical patent/DK143698C/da
Priority to DK115783A priority Critical patent/DK115783A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK83575A 1974-03-04 1975-03-03 Analogifremgangsmaade til fremstilling af 1-aminoalkyl-2-aryl-cyclohexylalkoholer og estere eller salte deraf DK143698C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK115783A DK115783A (da) 1974-03-04 1983-03-10 Fremgangsmaade til fremstilling af 1-(aminoalkyl)-2-phenylcyclohexylalkoholer og -estere deraf

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44780474A 1974-03-04 1974-03-04
US44780474 1974-03-04
US54507475 1975-01-29
US05/545,074 US3974157A (en) 1974-03-04 1975-01-29 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters

Publications (3)

Publication Number Publication Date
DK83575A DK83575A (da) 1975-09-05
DK143698B DK143698B (da) 1981-09-28
DK143698C true DK143698C (da) 1982-03-08

Family

ID=27035098

Family Applications (2)

Application Number Title Priority Date Filing Date
DK83575A DK143698C (da) 1974-03-04 1975-03-03 Analogifremgangsmaade til fremstilling af 1-aminoalkyl-2-aryl-cyclohexylalkoholer og estere eller salte deraf
DK328479A DK328479A (da) 1974-03-04 1979-08-03 Fremgangsmaade til fremstilling af 1-(aminoalkyl)-2-aryl-cyclohexan-alkoholer og estere

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK328479A DK328479A (da) 1974-03-04 1979-08-03 Fremgangsmaade til fremstilling af 1-(aminoalkyl)-2-aryl-cyclohexan-alkoholer og estere

Country Status (13)

Country Link
US (1) US3974157A (da)
JP (1) JPS50157342A (da)
BE (1) BE826260A (da)
CH (4) CH621329A5 (da)
DK (2) DK143698C (da)
FI (1) FI60205C (da)
FR (1) FR2262974B1 (da)
GB (1) GB1474004A (da)
IE (1) IE40733B1 (da)
LU (1) LU71964A1 (da)
NL (1) NL7502450A (da)
NO (1) NO140100C (da)
SE (2) SE7502407L (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115589A (en) * 1977-05-17 1978-09-19 The Upjohn Company Compounds, compositions and method of use
US4306097A (en) * 1977-09-13 1981-12-15 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents
US4366172A (en) * 1977-09-29 1982-12-28 The Upjohn Company 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use
FR2472559A1 (fr) * 1979-12-31 1981-07-03 Cerm Cent Europ Rech Mauvernay Derives du 1-aminomethyl 2-phenoxy cyclohexanol, procede d'obtention, application en therapeutique et compositions les contenant
US4391827A (en) * 1980-09-08 1983-07-05 Pfizer Inc. 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor
US4831059A (en) * 1980-09-19 1989-05-16 Pfizer Inc. Producing analgesia with pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes derivatives
US4486609A (en) * 1981-03-16 1984-12-04 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4933475A (en) * 1980-09-19 1990-06-12 Pfizer, Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4593131A (en) * 1980-09-19 1986-06-03 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4835192A (en) * 1980-09-19 1989-05-30 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4285867A (en) * 1980-09-19 1981-08-25 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4921994A (en) * 1980-09-19 1990-05-01 Pfizer Inc. Pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes and derivatives thereof
US4371720A (en) * 1980-09-19 1983-02-01 Pfizer Inc. 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives
US4331602A (en) * 1980-09-19 1982-05-25 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted]phenyl)naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
US4739079A (en) * 1980-09-19 1988-04-19 Pfizer Inc. Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor
JPS57122041A (en) * 1981-01-21 1982-07-29 Suntory Ltd Phenylclohexane derivative
US4847414A (en) * 1981-10-19 1989-07-11 Hoechst-Roussel Pharmaceuticals, Inc. 2'-substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and intermediates thereof
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
DE3467341D1 (en) * 1983-08-19 1987-12-17 Pennwalt Corp Cyclohexane carboxylic acids and derivatives thereof as antidysrhythmic agents
GB8405112D0 (en) * 1984-02-28 1984-04-04 Akzo Nv Anti-arrhythmic amino-alcohols
US4760146A (en) * 1986-02-18 1988-07-26 Pennwalt Corporation Cyclohexene carboxylic esters and amides as antidysrhythmic agents
US5248830A (en) * 1989-08-24 1993-09-28 Rhone-Poulenc Rorer Pharmaceuticals Inc. Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydro-pyran-2-ones
AU2023292A (en) * 1991-02-11 1992-09-15 Rhone-Poulenc Rorer International (Holdings) Inc. Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydropyran-2-ones
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) * 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
DE10000311A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Aminomethyl-Phonyl-Cyclohexanonderivate
DE10048714A1 (de) * 2000-09-30 2002-04-11 Gruenenthal Gmbh 5-Amino-1-penlen-3-ol-Derivate
RU2470011C2 (ru) * 2007-05-31 2012-12-20 Сепракор Инк. Циклоалкиламины, содержащие в качестве заместителя фенил, как ингибиторы обратного захвата моноаминов
US10968209B2 (en) 2016-05-19 2021-04-06 Glaxosmithkline Intellectual Property (No.2) Limited TRPV4 antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2586512A (en) * 1948-09-15 1952-02-19 Searle & Co Cyclohexyl-amino-alcohols
US2680115A (en) * 1949-01-28 1954-06-01 Maurice L Tainter Substituted tertiary-aminoalkyl carbinols
US2656386A (en) * 1951-02-24 1953-10-20 Upjohn Co Aminoethylhydrocarbonoxycyclohexenes
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols

Also Published As

Publication number Publication date
CH621329A5 (da) 1981-01-30
DK143698B (da) 1981-09-28
FI60205C (fi) 1981-12-10
JPS50157342A (da) 1975-12-19
FI60205B (fi) 1981-08-31
CH619207A5 (en) 1980-09-15
BE826260A (nl) 1975-06-30
FI750601A (da) 1975-09-05
NO140100C (no) 1979-07-04
DK328479A (da) 1979-08-03
CH615413A5 (en) 1980-01-31
CH617921A5 (en) 1980-06-30
NL7502450A (nl) 1975-09-08
SE8203051L (sv) 1982-05-14
GB1474004A (en) 1977-05-18
FR2262974B1 (da) 1980-01-25
US3974157A (en) 1976-08-10
NO140100B (no) 1979-03-26
NO750706L (da) 1975-09-05
DK83575A (da) 1975-09-05
SE7502407L (da) 1975-09-05
FR2262974A1 (da) 1975-10-03
IE40733B1 (en) 1979-08-01
IE40733L (en) 1975-09-04
LU71964A1 (da) 1975-08-20
AU7877375A (en) 1976-09-09

Similar Documents

Publication Publication Date Title
DK143698C (da) Analogifremgangsmaade til fremstilling af 1-aminoalkyl-2-aryl-cyclohexylalkoholer og estere eller salte deraf
DK154939C (da) Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DK146595C (da) Analogifremgangsmaade til fremstilling af substituerede 9-alkoxymethyl- eller -alkylthiomethylpuriner eller salte heraf
DK145119C (da) Analogifremgangsmaade til fremstilling af phenolethere eller syreadditionssalte deraf
DK145339C (da) Analogifremgangsmaade til fremstilling af 4-amino-5-hexensyre eller farmaceutisk acceptable salte deraf
DK139965B (da) Analogifremgangsmaade til fremstilling af 4-(j-metoksy-fenyl)-2-pyrrolidoner
DK148018C (da) Fremgangsmaade til fremstilling af l-phenylglycin og d-phenylglycinamid eller d-phenylglycin
DK406475A (da) Fremgangsmade til felles bestemmelse eller enkeltbestemmelse af isoenzymerne af lactatdehydrogenase
DK157246C (da) Analogifremgangsmaade til fremstilling af n-acylamino-alfa-phenylacetamidocephalosporiner eller farmaceutisk acceptable salte heraf.
DK147483C (da) Analogifremgangsmaade til fremstilling af cephalosporansyrederivater eller estere og salte deraf
DK157138C (da) Fremgangsmaade til fremstilling af 7beta-acylamino-7alfa-alkoxycephalosporiner eller 6beta-acylamino-6alfa-alkoxypenicilliner
DK149230C (da) Analogifremgangsmaade til fremstilling af 5-benzoyl-6-hydroxy-indan-1-carboxylsyrederivater eller farmaceutisk acceptable salte deraf
DK139724C (da) Analogifremgangsmaade til fremstilling af pyridobenzodiazepinoner eller salte heraf
DK225075A (da) Fremgangsmade til fremstilling af alfa-6--desoxy5-hydroxytetracyclin
DK145263C (da) Analogifremgangsmaade til fremstilling af imidazothiaziner eller farmaceutisk acceptable salte deraf
DK159267C (da) Analogifremgangsmaade til fremstilling af taurinderivater eller homotaurinderivater eller fysiologisk acceptable salte deraf
DK147854C (da) Analogifremgangsmaade til fremstilling af n-(1-benzylpiperid-4-yl)-benzamider
DK143278C (da) Analogifremgangsmaade til fremstilling af n-(r-tetrahydrofurfuryl)-noroxymorphon eller syreadditionssalte deraf
DK153759C (da) Analogifremgangsmaade til fremstilling af prostansyrederivater
DK146718C (da) Analogifremgangsmaade til fremstilling af benzobicyklononener
DK146127C (da) Analogifremgangsmaade til fremstilling af 5-(2-hydroxy-n-propoxy)-4-oxo-8-n-propyl-4h-1-benzopyran-2-carboxylsyre eller salte eller estre deraf
DK474375A (da) Fremgangsmade til fremstilling af racemisk 2-deutero-3-fluor-alanin eller salte deraf samt mellemprodukt til anvendelse under fremgangsmaden
DK141068C (da) Analogifremgangsmaade til fremstilling af indolkinolizidinderivater eller salte eller optisk aktive isomerer deraf
DK326475A (da) Fremgangsmade til fremstilling af nbetasubstituerede 8-beta-aminoethylergolin-iderivater og salte deraf
DK298075A (da) N-dithiophosphoryl-carbamidsyreestere samt fremgangsmader til deres fremstilling og anvendelse

Legal Events

Date Code Title Description
PBP Patent lapsed