DK474375A - Fremgangsmade til fremstilling af racemisk 2-deutero-3-fluor-alanin eller salte deraf samt mellemprodukt til anvendelse under fremgangsmaden - Google Patents

Fremgangsmade til fremstilling af racemisk 2-deutero-3-fluor-alanin eller salte deraf samt mellemprodukt til anvendelse under fremgangsmaden

Info

Publication number
DK474375A
DK474375A DK474375A DK474375A DK474375A DK 474375 A DK474375 A DK 474375A DK 474375 A DK474375 A DK 474375A DK 474375 A DK474375 A DK 474375A DK 474375 A DK474375 A DK 474375A
Authority
DK
Denmark
Prior art keywords
procedure
deutero
fluor
racemic
alanine
Prior art date
Application number
DK474375A
Other languages
English (en)
Inventor
U-H Dolling
E J J Grabowski
E F Schoenewaldt
M Sletzinger
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK474375A publication Critical patent/DK474375A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
DK474375A 1974-11-08 1975-10-22 Fremgangsmade til fremstilling af racemisk 2-deutero-3-fluor-alanin eller salte deraf samt mellemprodukt til anvendelse under fremgangsmaden DK474375A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/522,185 US3972921A (en) 1974-11-08 1974-11-08 Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

Publications (1)

Publication Number Publication Date
DK474375A true DK474375A (da) 1976-05-09

Family

ID=24079796

Family Applications (1)

Application Number Title Priority Date Filing Date
DK474375A DK474375A (da) 1974-11-08 1975-10-22 Fremgangsmade til fremstilling af racemisk 2-deutero-3-fluor-alanin eller salte deraf samt mellemprodukt til anvendelse under fremgangsmaden

Country Status (26)

Country Link
US (1) US3972921A (da)
JP (1) JPS5926614B2 (da)
AR (1) AR208722A1 (da)
AT (1) AT344136B (da)
BE (1) BE835358A (da)
CA (1) CA1053697A (da)
CH (1) CH622772A5 (da)
CS (1) CS199501B2 (da)
DD (1) DD125839A5 (da)
DE (1) DE2550121C2 (da)
DK (1) DK474375A (da)
ES (1) ES442154A1 (da)
FI (1) FI752919A (da)
FR (1) FR2290418A1 (da)
GB (1) GB1480886A (da)
HU (1) HU172273B (da)
IE (1) IE42060B1 (da)
IT (1) IT1048054B (da)
LU (1) LU73734A1 (da)
NL (1) NL7512383A (da)
NO (1) NO147671C (da)
PL (1) PL102608B1 (da)
SE (1) SE7511734L (da)
SU (1) SU626689A3 (da)
YU (1) YU39750B (da)
ZA (1) ZA757012B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028405A (en) * 1974-10-15 1977-06-07 Merck & Co., Inc. Fluorinated amino acids
US4049708A (en) * 1976-03-04 1977-09-20 Merck & Co., Inc. Fluorodesulfurization of alkyl mercaptans or alkyl dithianes
NZ194348A (en) * 1979-07-26 1982-09-14 Merrell Toraude & Co Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
JPS56113733A (en) * 1979-12-29 1981-09-07 Daikin Ind Ltd 3-substituted-3-fluoropyruvic acid, its ester, salt and preparation thereof
US4582931A (en) * 1984-12-24 1986-04-15 Merck & Co., Inc. Preparation of 2-Deutero-D-serine
US5254730A (en) * 1992-01-14 1993-10-19 Kilgore James L Production of amino acids and amino acid derivatives bearing isotopic hydrogen labels
FR2707309B1 (fr) * 1993-07-09 1995-08-11 Trefileurope France Sa Câble de levage.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2610212A (en) * 1950-04-24 1952-09-09 Gen Mills Inc Synthesis of amino acids
US2839547A (en) * 1955-07-30 1958-06-17 Inventa Ag Process for the production of aminocarboxylic acids
JPS4936389B1 (da) * 1969-03-03 1974-09-30
US3585361A (en) * 1969-06-18 1971-06-15 Nordson Corp Supply system for heating and dispensing molten thermoplastic material
JPS4841007B1 (da) * 1970-10-22 1973-12-04
JPS5225415B2 (da) * 1972-01-17 1977-07-07
JPS4935435A (da) * 1972-08-09 1974-04-02

Also Published As

Publication number Publication date
DE2550121A1 (de) 1976-05-20
US3972921A (en) 1976-08-03
ZA757012B (en) 1977-06-29
CH622772A5 (da) 1981-04-30
PL102608B1 (pl) 1979-04-30
NO147671B (no) 1983-02-14
CA1053697A (en) 1979-05-01
DE2550121C2 (de) 1984-08-16
LU73734A1 (da) 1976-09-06
YU39750B (en) 1985-04-30
IE42060L (en) 1976-05-08
AR208722A1 (es) 1977-02-28
ATA838775A (de) 1977-11-15
YU272275A (en) 1982-02-28
CS199501B2 (en) 1980-07-31
NO147671C (no) 1983-05-25
JPS5170722A (en) 1976-06-18
AT344136B (de) 1978-07-10
JPS5926614B2 (ja) 1984-06-29
FI752919A (da) 1976-05-09
FR2290418B1 (da) 1979-01-05
SE7511734L (sv) 1976-05-10
NL7512383A (nl) 1976-05-11
ES442154A1 (es) 1977-07-01
DD125839A5 (da) 1977-05-25
NO753561L (da) 1976-05-11
AU8605675A (en) 1977-05-05
BE835358A (fr) 1976-05-07
IT1048054B (it) 1980-11-20
FR2290418A1 (fr) 1976-06-04
SU626689A3 (ru) 1978-09-30
IE42060B1 (en) 1980-05-21
GB1480886A (en) 1977-07-27
HU172273B (hu) 1978-07-28

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment