ES442154A1 - Un procedimiento para la preparacion de nuevos compuestos deacido 2-deutero-3-fluor-dl-alanina. - Google Patents

Un procedimiento para la preparacion de nuevos compuestos deacido 2-deutero-3-fluor-dl-alanina.

Info

Publication number
ES442154A1
ES442154A1 ES442154A ES442154A ES442154A1 ES 442154 A1 ES442154 A1 ES 442154A1 ES 442154 A ES442154 A ES 442154A ES 442154 A ES442154 A ES 442154A ES 442154 A1 ES442154 A1 ES 442154A1
Authority
ES
Spain
Prior art keywords
fluoro
salts
deutero
alanine
racemic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES442154A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES442154A1 publication Critical patent/ES442154A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES442154A 1974-11-08 1975-10-28 Un procedimiento para la preparacion de nuevos compuestos deacido 2-deutero-3-fluor-dl-alanina. Expired ES442154A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/522,185 US3972921A (en) 1974-11-08 1974-11-08 Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

Publications (1)

Publication Number Publication Date
ES442154A1 true ES442154A1 (es) 1977-07-01

Family

ID=24079796

Family Applications (1)

Application Number Title Priority Date Filing Date
ES442154A Expired ES442154A1 (es) 1974-11-08 1975-10-28 Un procedimiento para la preparacion de nuevos compuestos deacido 2-deutero-3-fluor-dl-alanina.

Country Status (26)

Country Link
US (1) US3972921A (es)
JP (1) JPS5926614B2 (es)
AR (1) AR208722A1 (es)
AT (1) AT344136B (es)
BE (1) BE835358A (es)
CA (1) CA1053697A (es)
CH (1) CH622772A5 (es)
CS (1) CS199501B2 (es)
DD (1) DD125839A5 (es)
DE (1) DE2550121C2 (es)
DK (1) DK474375A (es)
ES (1) ES442154A1 (es)
FI (1) FI752919A (es)
FR (1) FR2290418A1 (es)
GB (1) GB1480886A (es)
HU (1) HU172273B (es)
IE (1) IE42060B1 (es)
IT (1) IT1048054B (es)
LU (1) LU73734A1 (es)
NL (1) NL7512383A (es)
NO (1) NO147671C (es)
PL (1) PL102608B1 (es)
SE (1) SE7511734L (es)
SU (1) SU626689A3 (es)
YU (1) YU39750B (es)
ZA (1) ZA757012B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028405A (en) * 1974-10-15 1977-06-07 Merck & Co., Inc. Fluorinated amino acids
US4049708A (en) * 1976-03-04 1977-09-20 Merck & Co., Inc. Fluorodesulfurization of alkyl mercaptans or alkyl dithianes
NZ194348A (en) * 1979-07-26 1982-09-14 Merrell Toraude & Co Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
JPS56113733A (en) * 1979-12-29 1981-09-07 Daikin Ind Ltd 3-substituted-3-fluoropyruvic acid, its ester, salt and preparation thereof
US4582931A (en) * 1984-12-24 1986-04-15 Merck & Co., Inc. Preparation of 2-Deutero-D-serine
US5254730A (en) * 1992-01-14 1993-10-19 Kilgore James L Production of amino acids and amino acid derivatives bearing isotopic hydrogen labels
FR2707309B1 (fr) * 1993-07-09 1995-08-11 Trefileurope France Sa Câble de levage.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2610212A (en) * 1950-04-24 1952-09-09 Gen Mills Inc Synthesis of amino acids
US2839547A (en) * 1955-07-30 1958-06-17 Inventa Ag Process for the production of aminocarboxylic acids
JPS4936389B1 (es) * 1969-03-03 1974-09-30
US3585361A (en) * 1969-06-18 1971-06-15 Nordson Corp Supply system for heating and dispensing molten thermoplastic material
JPS4841007B1 (es) * 1970-10-22 1973-12-04
JPS5225415B2 (es) * 1972-01-17 1977-07-07
JPS4935435A (es) * 1972-08-09 1974-04-02

Also Published As

Publication number Publication date
NL7512383A (nl) 1976-05-11
GB1480886A (en) 1977-07-27
US3972921A (en) 1976-08-03
BE835358A (fr) 1976-05-07
IT1048054B (it) 1980-11-20
FR2290418A1 (fr) 1976-06-04
CS199501B2 (en) 1980-07-31
LU73734A1 (es) 1976-09-06
ZA757012B (en) 1977-06-29
DE2550121A1 (de) 1976-05-20
SE7511734L (sv) 1976-05-10
NO753561L (es) 1976-05-11
IE42060B1 (en) 1980-05-21
JPS5170722A (en) 1976-06-18
DK474375A (da) 1976-05-09
AR208722A1 (es) 1977-02-28
AU8605675A (en) 1977-05-05
IE42060L (en) 1976-05-08
CH622772A5 (es) 1981-04-30
YU272275A (en) 1982-02-28
ATA838775A (de) 1977-11-15
DD125839A5 (es) 1977-05-25
SU626689A3 (ru) 1978-09-30
YU39750B (en) 1985-04-30
FR2290418B1 (es) 1979-01-05
FI752919A (es) 1976-05-09
DE2550121C2 (de) 1984-08-16
PL102608B1 (pl) 1979-04-30
NO147671B (no) 1983-02-14
HU172273B (hu) 1978-07-28
NO147671C (no) 1983-05-25
JPS5926614B2 (ja) 1984-06-29
AT344136B (de) 1978-07-10
CA1053697A (en) 1979-05-01

Similar Documents

Publication Publication Date Title
ES2017839A6 (es) Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales>
ES456567A1 (es) Procedimiento para la preparacion de nuevos derivados de e- ritromicina.
ES445250A1 (es) Un procedimiento para halogenar productos intermedios para la obtencion de anillos de cefem.
YU159475A (en) Process for obtaining new benzimidazoline derivatives
ES436311A1 (es) Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3-alquinilaminopropanos.
ES442154A1 (es) Un procedimiento para la preparacion de nuevos compuestos deacido 2-deutero-3-fluor-dl-alanina.
ES434533A1 (es) Un procedimiento para la preparacion de compuestos tetraci-clicos.
ES375933A1 (es) Un metodo de preparar un compuesto de 2-amino-4-hidroxi-6- hidroximetil-7, 7 - dimetil - 7,8 - dihidropteridinao una forma tautomera de la misma.
ES450897A1 (es) Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona.
ES414365A1 (es) Procedimiento para la preparacion de nuevos derivados del acido p-dihidroxibencenodisulfonico.
HU172474B (hu) Sposob poluchenija okristallizovannojj 7-skobka-d-2-gidroksi-2-fenil-acetamido-skobka zakryta-3-skobka-1-metil-1h-tetrazol-5-il-tio-metil-skobka zakryta-3-cefem-4-karbonovojj kisloty i natrievojj soly to est' natrievogo cefamandola
ES440046A1 (es) Un procedimiento para la preparacion del antibiotico xk-62- 2.
ES468127A1 (es) Un procedimiento para la preparacion de nuevos derivados de pirido (2,1-b) quinazolina
ES447176A1 (es) Procedimiento para la preparacion de aminoacidos.
ES454023A1 (es) Procedimiento para la obtencion de una nueva forma cristali-na de sal sodica del cefacetrilo.
RO84457B (ro) Procedeu pentru prepararea unor derivati de acid 7-beta-aminooxazolilacetilamino-3-cefem-4-carboxilic
GB1461068A (en) Preparation of a sulphur-containing pyridine derivative
ES333664A1 (es) Un procedimiento para la preparacion de agentes antibacterianos.
SE7708686L (sv) Mellanprodukter och forfarande for framstellning derav
IL45482A0 (en) Novel 1-(m-acyloxyphenyl)-1-hydroxy-2-n-alkylamino ethanes,their acid addition salts,pharmaceutical compositions containing same as well as processes for their production
IT1221058B (it) Composti amminici come intermedi nella produzione di agenti selettivi sui ricettori istaminici e procedimenti per la produzione di detti composti amminici
GB1366554A (en) Phenylalanine derivatives and a process for their preparation
ES443720A1 (es) Un procedimiento para la produccion de derivados de acidos 20-alcoxi-16-alquilprostadienoicos.
CH609332A5 (en) Process for the preparation of novel 3-aryloxy-3-phenyl-propylamines
ES405105A1 (es) Un procedimiento para la preparacion de 2,6,6-trimetil-1-(10' - carboxi - 3',7'-dimetil - deca - 1',3',5',7',9' - pen- taenil)-cicolhexi-eno o una sal del mismo.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202