FR2290418A1 - Synthese de la 2-deutero-3-fluoro-alanine racemique et de ses sels et produits intermediaires dans cette synthese - Google Patents

Synthese de la 2-deutero-3-fluoro-alanine racemique et de ses sels et produits intermediaires dans cette synthese

Info

Publication number
FR2290418A1
FR2290418A1 FR7533779A FR7533779A FR2290418A1 FR 2290418 A1 FR2290418 A1 FR 2290418A1 FR 7533779 A FR7533779 A FR 7533779A FR 7533779 A FR7533779 A FR 7533779A FR 2290418 A1 FR2290418 A1 FR 2290418A1
Authority
FR
France
Prior art keywords
synthesis
deutero
racemic
alanine
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7533779A
Other languages
English (en)
Other versions
FR2290418B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2290418A1 publication Critical patent/FR2290418A1/fr
Application granted granted Critical
Publication of FR2290418B1 publication Critical patent/FR2290418B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7533779A 1974-11-08 1975-11-05 Synthese de la 2-deutero-3-fluoro-alanine racemique et de ses sels et produits intermediaires dans cette synthese Granted FR2290418A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/522,185 US3972921A (en) 1974-11-08 1974-11-08 Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

Publications (2)

Publication Number Publication Date
FR2290418A1 true FR2290418A1 (fr) 1976-06-04
FR2290418B1 FR2290418B1 (fr) 1979-01-05

Family

ID=24079796

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7533779A Granted FR2290418A1 (fr) 1974-11-08 1975-11-05 Synthese de la 2-deutero-3-fluoro-alanine racemique et de ses sels et produits intermediaires dans cette synthese

Country Status (26)

Country Link
US (1) US3972921A (fr)
JP (1) JPS5926614B2 (fr)
AR (1) AR208722A1 (fr)
AT (1) AT344136B (fr)
BE (1) BE835358A (fr)
CA (1) CA1053697A (fr)
CH (1) CH622772A5 (fr)
CS (1) CS199501B2 (fr)
DD (1) DD125839A5 (fr)
DE (1) DE2550121C2 (fr)
DK (1) DK474375A (fr)
ES (1) ES442154A1 (fr)
FI (1) FI752919A (fr)
FR (1) FR2290418A1 (fr)
GB (1) GB1480886A (fr)
HU (1) HU172273B (fr)
IE (1) IE42060B1 (fr)
IT (1) IT1048054B (fr)
LU (1) LU73734A1 (fr)
NL (1) NL7512383A (fr)
NO (1) NO147671C (fr)
PL (1) PL102608B1 (fr)
SE (1) SE7511734L (fr)
SU (1) SU626689A3 (fr)
YU (1) YU39750B (fr)
ZA (1) ZA757012B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028405A (en) * 1974-10-15 1977-06-07 Merck & Co., Inc. Fluorinated amino acids
US4049708A (en) * 1976-03-04 1977-09-20 Merck & Co., Inc. Fluorodesulfurization of alkyl mercaptans or alkyl dithianes
NZ194348A (en) * 1979-07-26 1982-09-14 Merrell Toraude & Co Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
JPS56113733A (en) * 1979-12-29 1981-09-07 Daikin Ind Ltd 3-substituted-3-fluoropyruvic acid, its ester, salt and preparation thereof
US4582931A (en) * 1984-12-24 1986-04-15 Merck & Co., Inc. Preparation of 2-Deutero-D-serine
US5254730A (en) * 1992-01-14 1993-10-19 Kilgore James L Production of amino acids and amino acid derivatives bearing isotopic hydrogen labels
FR2707309B1 (fr) * 1993-07-09 1995-08-11 Trefileurope France Sa Câble de levage.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2610212A (en) * 1950-04-24 1952-09-09 Gen Mills Inc Synthesis of amino acids
US2839547A (en) * 1955-07-30 1958-06-17 Inventa Ag Process for the production of aminocarboxylic acids
JPS4936389B1 (fr) * 1969-03-03 1974-09-30
US3585361A (en) * 1969-06-18 1971-06-15 Nordson Corp Supply system for heating and dispensing molten thermoplastic material
JPS4841007B1 (fr) * 1970-10-22 1973-12-04
JPS5225415B2 (fr) * 1972-01-17 1977-07-07
JPS4935435A (fr) * 1972-08-09 1974-04-02

Also Published As

Publication number Publication date
NL7512383A (nl) 1976-05-11
GB1480886A (en) 1977-07-27
US3972921A (en) 1976-08-03
BE835358A (fr) 1976-05-07
IT1048054B (it) 1980-11-20
ES442154A1 (es) 1977-07-01
CS199501B2 (en) 1980-07-31
LU73734A1 (fr) 1976-09-06
ZA757012B (en) 1977-06-29
DE2550121A1 (de) 1976-05-20
SE7511734L (sv) 1976-05-10
NO753561L (fr) 1976-05-11
IE42060B1 (en) 1980-05-21
JPS5170722A (en) 1976-06-18
DK474375A (da) 1976-05-09
AR208722A1 (es) 1977-02-28
AU8605675A (en) 1977-05-05
IE42060L (en) 1976-05-08
CH622772A5 (fr) 1981-04-30
YU272275A (en) 1982-02-28
ATA838775A (de) 1977-11-15
DD125839A5 (fr) 1977-05-25
SU626689A3 (ru) 1978-09-30
YU39750B (en) 1985-04-30
FR2290418B1 (fr) 1979-01-05
FI752919A (fr) 1976-05-09
DE2550121C2 (de) 1984-08-16
PL102608B1 (pl) 1979-04-30
NO147671B (no) 1983-02-14
HU172273B (hu) 1978-07-28
NO147671C (no) 1983-05-25
JPS5926614B2 (ja) 1984-06-29
AT344136B (de) 1978-07-10
CA1053697A (fr) 1979-05-01

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Legal Events

Date Code Title Description
ST Notification of lapse