DK398577A - Fremgangsmaade til fremstilling af dimere indoldihydroindol-carboxamider eller salte deraf - Google Patents

Fremgangsmaade til fremstilling af dimere indoldihydroindol-carboxamider eller salte deraf

Info

Publication number
DK398577A
DK398577A DK398577A DK398577A DK398577A DK 398577 A DK398577 A DK 398577A DK 398577 A DK398577 A DK 398577A DK 398577 A DK398577 A DK 398577A DK 398577 A DK398577 A DK 398577A
Authority
DK
Denmark
Prior art keywords
indold
dimere
dihydroindol
carboxamides
salts
Prior art date
Application number
DK398577A
Other languages
English (en)
Other versions
DK146822B (da
DK146822C (da
Inventor
G J Cullinan
K Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK398577A publication Critical patent/DK398577A/da
Publication of DK146822B publication Critical patent/DK146822B/da
Application granted granted Critical
Publication of DK146822C publication Critical patent/DK146822C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK398577A 1976-09-08 1977-09-07 Analogifremgangsmaade til fremstilling af derivater af 4-desacetyl-vinblastin eller salte deraf DK146822C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08
US72165076 1976-09-08

Publications (3)

Publication Number Publication Date
DK398577A true DK398577A (da) 1978-03-09
DK146822B DK146822B (da) 1984-01-16
DK146822C DK146822C (da) 1984-06-25

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
DK398577A DK146822C (da) 1976-09-08 1977-09-07 Analogifremgangsmaade til fremstilling af derivater af 4-desacetyl-vinblastin eller salte deraf

Country Status (27)

Country Link
JP (1) JPS5340799A (da)
AR (3) AR226411A1 (da)
AT (1) AT360513B (da)
AU (1) AU511055B2 (da)
BE (1) BE858451A (da)
CA (1) CA1082179A (da)
CH (1) CH631990A5 (da)
DD (1) DD133055A5 (da)
DE (1) DE2739443A1 (da)
DK (1) DK146822C (da)
ES (1) ES462229A1 (da)
FR (1) FR2364220A1 (da)
GB (1) GB1586709A (da)
GR (1) GR69783B (da)
HU (1) HU180722B (da)
IE (1) IE45558B1 (da)
IL (1) IL52731A0 (da)
MX (1) MX4740E (da)
NL (1) NL7709806A (da)
NZ (1) NZ184932A (da)
PH (1) PH14771A (da)
PL (1) PL104309B1 (da)
PT (1) PT66984B (da)
RO (3) RO77921A (da)
SE (1) SE434953B (da)
YU (1) YU209777A (da)
ZA (1) ZA774988B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
US4831038A (en) * 1986-01-13 1989-05-16 Ire-Celltarg S.A. Vinblastine derivatives and pharmaceutical composition containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Also Published As

Publication number Publication date
AU511055B2 (en) 1980-07-24
PL200607A1 (pl) 1978-05-22
IE45558B1 (en) 1982-09-22
ES462229A1 (es) 1978-07-16
DK146822B (da) 1984-01-16
CH631990A5 (en) 1982-09-15
AR231643A1 (es) 1985-01-31
BE858451A (fr) 1978-03-07
GR69783B (da) 1982-07-07
GB1586709A (en) 1981-03-25
AR226411A1 (es) 1982-07-15
RO77921A (ro) 1981-12-25
YU209777A (en) 1982-08-31
DE2739443A1 (de) 1978-03-09
JPS5340799A (en) 1978-04-13
JPS624398B2 (da) 1987-01-30
AT360513B (de) 1981-01-12
MX4740E (es) 1982-08-25
RO77922A (ro) 1981-12-25
IE771700L (en) 1978-03-08
NZ184932A (en) 1979-11-01
PT66984A (en) 1977-10-01
DK146822C (da) 1984-06-25
DE2739443C2 (da) 1991-08-14
FR2364220B1 (da) 1980-04-25
ZA774988B (en) 1979-03-28
ATA644277A (de) 1980-06-15
AR230642A1 (es) 1984-05-31
CA1082179A (en) 1980-07-22
FR2364220A1 (fr) 1978-04-07
SE434953B (sv) 1984-08-27
SE7710059L (sv) 1978-03-09
PL104309B1 (pl) 1979-08-31
HU180722B (en) 1983-04-29
AU2803977A (en) 1979-02-22
PH14771A (en) 1981-12-09
IL52731A0 (en) 1977-10-31
RO72474A (ro) 1982-05-10
PT66984B (en) 1979-02-13
DD133055A5 (de) 1978-11-29
NL7709806A (nl) 1978-03-10

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