JPS5340799A - Novel amide derivative of dimer alkaloid - Google Patents

Novel amide derivative of dimer alkaloid

Info

Publication number
JPS5340799A
JPS5340799A JP10834477A JP10834477A JPS5340799A JP S5340799 A JPS5340799 A JP S5340799A JP 10834477 A JP10834477 A JP 10834477A JP 10834477 A JP10834477 A JP 10834477A JP S5340799 A JPS5340799 A JP S5340799A
Authority
JP
Japan
Prior art keywords
amide derivative
novel amide
dimer alkaloid
alkaloid
dimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10834477A
Other languages
English (en)
Other versions
JPS624398B2 (ja
Inventor
Jiei Karinan Jiyooji
Geruzon Kooruto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPS5340799A publication Critical patent/JPS5340799A/ja
Publication of JPS624398B2 publication Critical patent/JPS624398B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP10834477A 1976-09-08 1977-09-08 Novel amide derivative of dimer alkaloid Granted JPS5340799A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08

Publications (2)

Publication Number Publication Date
JPS5340799A true JPS5340799A (en) 1978-04-13
JPS624398B2 JPS624398B2 (ja) 1987-01-30

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10834477A Granted JPS5340799A (en) 1976-09-08 1977-09-08 Novel amide derivative of dimer alkaloid

Country Status (27)

Country Link
JP (1) JPS5340799A (ja)
AR (3) AR226411A1 (ja)
AT (1) AT360513B (ja)
AU (1) AU511055B2 (ja)
BE (1) BE858451A (ja)
CA (1) CA1082179A (ja)
CH (1) CH631990A5 (ja)
DD (1) DD133055A5 (ja)
DE (1) DE2739443A1 (ja)
DK (1) DK146822C (ja)
ES (1) ES462229A1 (ja)
FR (1) FR2364220A1 (ja)
GB (1) GB1586709A (ja)
GR (1) GR69783B (ja)
HU (1) HU180722B (ja)
IE (1) IE45558B1 (ja)
IL (1) IL52731A0 (ja)
MX (1) MX4740E (ja)
NL (1) NL7709806A (ja)
NZ (1) NZ184932A (ja)
PH (1) PH14771A (ja)
PL (1) PL104309B1 (ja)
PT (1) PT66984B (ja)
RO (3) RO77922A (ja)
SE (1) SE434953B (ja)
YU (1) YU209777A (ja)
ZA (1) ZA774988B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62175486A (ja) * 1986-01-13 1987-08-01 ラ　レジョン　ワロン ビンブラスチン誘導体

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62175486A (ja) * 1986-01-13 1987-08-01 ラ　レジョン　ワロン ビンブラスチン誘導体
JPH075608B2 (ja) * 1986-01-13 1995-01-25 イ−ル−セルタ−ク ソシエテ アノニム ビンブラスチン誘導体

Also Published As

Publication number Publication date
PH14771A (en) 1981-12-09
IE45558B1 (en) 1982-09-22
AR230642A1 (es) 1984-05-31
AT360513B (de) 1981-01-12
DE2739443C2 (ja) 1991-08-14
AR226411A1 (es) 1982-07-15
GB1586709A (en) 1981-03-25
GR69783B (ja) 1982-07-07
MX4740E (es) 1982-08-25
SE7710059L (sv) 1978-03-09
AU2803977A (en) 1979-02-22
DK398577A (da) 1978-03-09
BE858451A (fr) 1978-03-07
DK146822B (da) 1984-01-16
SE434953B (sv) 1984-08-27
RO72474A (ro) 1982-05-10
RO77922A (ro) 1981-12-25
NL7709806A (nl) 1978-03-10
PL200607A1 (pl) 1978-05-22
JPS624398B2 (ja) 1987-01-30
AR231643A1 (es) 1985-01-31
RO77921A (ro) 1981-12-25
IE771700L (en) 1978-03-08
ZA774988B (en) 1979-03-28
FR2364220A1 (fr) 1978-04-07
IL52731A0 (en) 1977-10-31
HU180722B (en) 1983-04-29
DE2739443A1 (de) 1978-03-09
NZ184932A (en) 1979-11-01
FR2364220B1 (ja) 1980-04-25
ES462229A1 (es) 1978-07-16
PT66984B (en) 1979-02-13
DK146822C (da) 1984-06-25
YU209777A (en) 1982-08-31
CH631990A5 (en) 1982-09-15
AU511055B2 (en) 1980-07-24
ATA644277A (de) 1980-06-15
PT66984A (en) 1977-10-01
CA1082179A (en) 1980-07-22
DD133055A5 (de) 1978-11-29
PL104309B1 (pl) 1979-08-31

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