ZA774988B - Novel amide derivatives of vlb,leurosidine,leurocristine and related dimeric alkaloids - Google Patents

Novel amide derivatives of vlb,leurosidine,leurocristine and related dimeric alkaloids

Info

Publication number
ZA774988B
ZA774988B ZA00774988A ZA774988A ZA774988B ZA 774988 B ZA774988 B ZA 774988B ZA 00774988 A ZA00774988 A ZA 00774988A ZA 774988 A ZA774988 A ZA 774988A ZA 774988 B ZA774988 B ZA 774988B
Authority
ZA
South Africa
Prior art keywords
leurocristine
leurosidine
vlb
amide derivatives
novel amide
Prior art date
Application number
ZA00774988A
Other languages
English (en)
Inventor
G Cullinan
K Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA774988B publication Critical patent/ZA774988B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA00774988A 1976-09-08 1977-08-17 Novel amide derivatives of vlb,leurosidine,leurocristine and related dimeric alkaloids ZA774988B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08

Publications (1)

Publication Number Publication Date
ZA774988B true ZA774988B (en) 1979-03-28

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00774988A ZA774988B (en) 1976-09-08 1977-08-17 Novel amide derivatives of vlb,leurosidine,leurocristine and related dimeric alkaloids

Country Status (27)

Country Link
JP (1) JPS5340799A (ja)
AR (3) AR226411A1 (ja)
AT (1) AT360513B (ja)
AU (1) AU511055B2 (ja)
BE (1) BE858451A (ja)
CA (1) CA1082179A (ja)
CH (1) CH631990A5 (ja)
DD (1) DD133055A5 (ja)
DE (1) DE2739443A1 (ja)
DK (1) DK146822C (ja)
ES (1) ES462229A1 (ja)
FR (1) FR2364220A1 (ja)
GB (1) GB1586709A (ja)
GR (1) GR69783B (ja)
HU (1) HU180722B (ja)
IE (1) IE45558B1 (ja)
IL (1) IL52731A0 (ja)
MX (1) MX4740E (ja)
NL (1) NL7709806A (ja)
NZ (1) NZ184932A (ja)
PH (1) PH14771A (ja)
PL (1) PL104309B1 (ja)
PT (1) PT66984B (ja)
RO (3) RO77921A (ja)
SE (1) SE434953B (ja)
YU (1) YU209777A (ja)
ZA (1) ZA774988B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Also Published As

Publication number Publication date
RO77922A (ro) 1981-12-25
ATA644277A (de) 1980-06-15
CH631990A5 (en) 1982-09-15
CA1082179A (en) 1980-07-22
PT66984B (en) 1979-02-13
PH14771A (en) 1981-12-09
FR2364220A1 (fr) 1978-04-07
JPS624398B2 (ja) 1987-01-30
SE434953B (sv) 1984-08-27
NZ184932A (en) 1979-11-01
YU209777A (en) 1982-08-31
IE771700L (en) 1978-03-08
IE45558B1 (en) 1982-09-22
AU2803977A (en) 1979-02-22
BE858451A (fr) 1978-03-07
IL52731A0 (en) 1977-10-31
GR69783B (ja) 1982-07-07
PL200607A1 (pl) 1978-05-22
HU180722B (en) 1983-04-29
DE2739443C2 (ja) 1991-08-14
RO77921A (ro) 1981-12-25
MX4740E (es) 1982-08-25
GB1586709A (en) 1981-03-25
PL104309B1 (pl) 1979-08-31
DE2739443A1 (de) 1978-03-09
FR2364220B1 (ja) 1980-04-25
PT66984A (en) 1977-10-01
RO72474A (ro) 1982-05-10
ES462229A1 (es) 1978-07-16
AR231643A1 (es) 1985-01-31
JPS5340799A (en) 1978-04-13
NL7709806A (nl) 1978-03-10
AT360513B (de) 1981-01-12
DD133055A5 (de) 1978-11-29
DK398577A (da) 1978-03-09
SE7710059L (sv) 1978-03-09
AR230642A1 (es) 1984-05-31
DK146822C (da) 1984-06-25
AU511055B2 (en) 1980-07-24
AR226411A1 (es) 1982-07-15
DK146822B (da) 1984-01-16

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