BE2015C066I2 - - Google Patents
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- Publication number
- BE2015C066I2 BE2015C066I2 BE2015C066C BE2015C066C BE2015C066I2 BE 2015C066 I2 BE2015C066 I2 BE 2015C066I2 BE 2015C066 C BE2015C066 C BE 2015C066C BE 2015C066 C BE2015C066 C BE 2015C066C BE 2015C066 I2 BE2015C066 I2 BE 2015C066I2
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55592604P | 2004-03-24 | 2004-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE2015C066I2 true BE2015C066I2 (h) | 2024-08-08 |
Family
ID=34964085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2015C066C BE2015C066I2 (h) | 2004-03-24 | 2015-12-09 |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US7700103B2 (h) |
| EP (1) | EP1730175B1 (h) |
| JP (1) | JP4833962B2 (h) |
| KR (1) | KR101203403B1 (h) |
| CN (1) | CN1934131B (h) |
| AR (1) | AR048191A1 (h) |
| AT (1) | ATE466022T1 (h) |
| AU (1) | AU2005230907C1 (h) |
| BE (1) | BE2015C066I2 (h) |
| BR (1) | BRPI0509079B8 (h) |
| CA (1) | CA2560487C (h) |
| CY (2) | CY1110349T1 (h) |
| DE (1) | DE602005020913D1 (h) |
| DK (1) | DK1730175T3 (h) |
| ES (1) | ES2343255T3 (h) |
| FR (1) | FR15C0085I2 (h) |
| HU (1) | HUS1500062I1 (h) |
| IL (1) | IL178140A (h) |
| LT (2) | LTPA2015050I1 (h) |
| LU (1) | LU92903I2 (h) |
| MY (1) | MY148656A (h) |
| NL (1) | NL300777I1 (h) |
| NO (3) | NO338055B1 (h) |
| NZ (1) | NZ549898A (h) |
| PL (1) | PL1730175T3 (h) |
| PT (1) | PT1730175E (h) |
| RU (1) | RU2373219C2 (h) |
| SI (1) | SI1730175T1 (h) |
| TW (1) | TWI349036B (h) |
| WO (1) | WO2005097821A1 (h) |
| ZA (1) | ZA200607575B (h) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7858098B2 (en) * | 2002-12-20 | 2010-12-28 | Glaxosmithkline Biologicals, S.A. | Vaccine |
| CN1869215B (zh) * | 2006-05-19 | 2012-07-04 | 长春百克生物科技股份公司 | 一种制备人乳头瘤病毒的病毒样颗粒的方法 |
| JP2010520874A (ja) | 2007-03-09 | 2010-06-17 | メルク・シャープ・エンド・ドーム・コーポレイション | パピローマウイルスワクチン組成物 |
| CN101440371B (zh) * | 2007-11-23 | 2012-09-05 | 上海泽润生物科技有限公司 | 一种16型人乳头状瘤病毒主要衣壳蛋白l1基因 |
| RU2494106C2 (ru) * | 2007-11-23 | 2013-09-27 | Шанхай Зеран Биотекнолоджи Ко., Лтд. | Гены, кодирующие главный капсидный белок l1 вируса папилломы человека, и их применение |
| KR102130584B1 (ko) * | 2010-05-14 | 2020-07-07 | 박스알타 인코퍼레이티드 | Ｏｓｐａ 키메라 및 백신에서 그의 용도 |
| CA2799205A1 (en) | 2010-05-25 | 2011-12-01 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
| US9499591B2 (en) | 2010-07-02 | 2016-11-22 | Xiamen University | Truncated L1 protein of human papillomavirus type 52 |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| CN103562392B (zh) | 2010-12-03 | 2016-07-20 | Ms技术有限责任公司 | 植物细胞中草甘膦抗性编码核酸分子的优化表达 |
| CN102154325B (zh) * | 2011-01-01 | 2013-08-21 | 上海生物制品研究所有限责任公司 | 针对人乳头瘤状病毒的疫苗及其制法和用途 |
| RU2445358C1 (ru) * | 2011-02-15 | 2012-03-20 | Закрытое акционерное общество научно-производственная компания "Комбиотех" | Рекомбинантный штамм дрожжей pichia angusta - продуцент капсидного белка l1 вируса папилломы человека типа 18 |
| RU2445357C1 (ru) * | 2011-02-15 | 2012-03-20 | Закрытое акционерное общество научно-производственная компания "Комбиотех" | Рекомбинантный штамм дрожжей pichia angusta - продуцент капсидного белка l1 вируса папилломы человека типа 16 |
| CN104120089B (zh) * | 2013-04-26 | 2019-09-24 | 北京安百胜生物科技有限公司 | 用汉逊酵母表达系统产生hpv52 l1蛋白的方法 |
| CN110592133A (zh) * | 2013-05-17 | 2019-12-20 | 北京安百胜生物科技有限公司 | 用汉逊酵母表达系统产生hpv31 l1蛋白的方法 |
| US9782470B2 (en) | 2013-10-16 | 2017-10-10 | Merck Sharp & Dohme Corp. | Method of obtaining thermostable dried vaccine formulations |
| CN104878022A (zh) * | 2015-04-27 | 2015-09-02 | 段青姣 | 编码hpv58l1、hpv52l1蛋白的核苷酸序列及其应用 |
| CN106701796B (zh) * | 2015-08-12 | 2021-11-16 | 北京康乐卫士生物技术股份有限公司 | 52型重组人乳头瘤病毒病毒样颗粒及其制备方法 |
| CN109750049B (zh) * | 2017-11-07 | 2023-08-18 | 上海泽润生物科技有限公司 | 重组人乳头瘤病毒52亚型蛋白表达 |
| PH12022552075A1 (en) | 2020-02-14 | 2024-02-12 | Merck Sharp & Dohme Llc | Hpv vaccine |
| CN114539365B (zh) * | 2020-11-26 | 2023-12-01 | 中国医学科学院基础医学研究所 | 一种改造的人乳头瘤病毒52型l1蛋白及其用途 |
| CN113073105B (zh) * | 2021-03-23 | 2023-06-13 | 重庆博唯佰泰生物制药有限公司 | 一种表达hpv 56l1的多核苷酸序列及其表达载体、宿主细胞和应用 |
| CN113549634B (zh) * | 2021-06-07 | 2023-03-31 | 郑州大学 | 编码可溶性hpv58 l1蛋白的基因及其重组质粒的构建与应用 |
| AR126708A1 (es) | 2021-08-06 | 2023-11-08 | Merck Sharp & Dohme Llc | Vacuna para el vph |
| US20230118665A1 (en) | 2021-08-19 | 2023-04-20 | Merck Sharp & Dohme Llc | Novel thermostable lipid nanoparticle and methods of use thereof |
| AR132886A1 (es) | 2023-06-09 | 2025-08-06 | Merck Sharp & Dohme Llc | Composiciones adyuvantes en nanoemulsión para vacunas contra el papilomavirus humano |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339729C (en) * | 1988-10-26 | 1998-03-17 | Wayne D. Lancaster | Human papillomavirus type 52 dna sequences and methods for employing thesame |
| IL117591A0 (en) | 1995-03-30 | 1996-07-23 | Merck & Co Inc | Synthetic DNA encoding human papillomavirus type 11 L1 protein |
| US5821087A (en) | 1995-03-30 | 1998-10-13 | Merck & Co., Inc. | Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA |
| KR20000070865A (ko) | 1997-02-07 | 2000-11-25 | 폴락 돈나 엘. | 합성 ＨＩＶ ｇａｇ 유전자 |
| JP4434479B2 (ja) | 1997-07-09 | 2010-03-17 | ザ・ユニバーシティ・オブ・クイーンズランド | 標的の細胞および組織においてタンパク質を選択的に発現するための核酸配列および方法 |
| DE69933875T2 (de) | 1998-08-14 | 2007-05-31 | Merck & Co., Inc. | Protein-verabreichungssystem, das dem menschlichen papillomavirus ähnliche partikel benützt. |
| BR9913026A (pt) * | 1998-08-14 | 2001-09-25 | Merck & Co Inc | Processo de purificação de partìculas semelhantes a vìrus (vlps) de papilomavìrus recombinante, e, processo de preparação de um produto de vlp de papilomavìrus humano purificado adequado para uso em uma vacina para humano |
| SE514982C2 (sv) * | 1999-09-30 | 2001-05-28 | Active Biotech Ab | Bärare innehållande ett huvudkapsidprotein L1 från humant papillomavirus samt dess användning |
| PT1212358E (pt) * | 1999-08-25 | 2005-04-29 | Merck & Co Inc | Genes sinteticos de papilomavirus humano |
| US6436402B1 (en) | 1999-10-15 | 2002-08-20 | Merck & Co., Inc. | Process for making human papillomavirus virus-like particles with improved properties |
| NZ523683A (en) | 2000-07-21 | 2004-08-27 | Glaxo Group Ltd | Codon-optimized papilloma virus sequences |
| US20030226155A1 (en) * | 2001-08-30 | 2003-12-04 | Biorexis Pharmaceutical Corporation | Modified transferrin-antibody fusion proteins |
| MXPA05010285A (es) | 2003-03-24 | 2005-11-17 | Merck & Co Inc | Expresion optimizada de hpv 31 l1 en levadura. |
| MY140664A (en) * | 2003-09-29 | 2010-01-15 | Merck Sharp & Dohme | Optimized expression of hpv 45 l1 in yeast |
| MY139500A (en) | 2003-11-12 | 2009-10-30 | Merck Sharp & Dohme | Optimized expression of hpv 58 l1 in yeast |
-
2005
- 2005-03-18 CA CA2560487A patent/CA2560487C/en not_active Expired - Lifetime
- 2005-03-18 PT PT05725933T patent/PT1730175E/pt unknown
- 2005-03-18 MY MYPI20051180A patent/MY148656A/en unknown
- 2005-03-18 KR KR1020067019673A patent/KR101203403B1/ko not_active Expired - Lifetime
- 2005-03-18 DK DK05725933.5T patent/DK1730175T3/da active
- 2005-03-18 DE DE602005020913T patent/DE602005020913D1/de not_active Expired - Lifetime
- 2005-03-18 WO PCT/US2005/009199 patent/WO2005097821A1/en active Application Filing
- 2005-03-18 AT AT05725933T patent/ATE466022T1/de active
- 2005-03-18 TW TW094108431A patent/TWI349036B/zh active
- 2005-03-18 NZ NZ549898A patent/NZ549898A/en not_active IP Right Cessation
- 2005-03-18 JP JP2007505032A patent/JP4833962B2/ja not_active Expired - Lifetime
- 2005-03-18 EP EP05725933A patent/EP1730175B1/en not_active Expired - Lifetime
- 2005-03-18 SI SI200531052T patent/SI1730175T1/sl unknown
- 2005-03-18 PL PL05725933T patent/PL1730175T3/pl unknown
- 2005-03-18 CN CN2005800095956A patent/CN1934131B/zh not_active Expired - Lifetime
- 2005-03-18 US US10/594,064 patent/US7700103B2/en active Active
- 2005-03-18 AU AU2005230907A patent/AU2005230907C1/en active Active
- 2005-03-18 ES ES05725933T patent/ES2343255T3/es not_active Expired - Lifetime
- 2005-03-18 RU RU2006137363/13A patent/RU2373219C2/ru active
- 2005-03-18 BR BRPI0509079A patent/BRPI0509079B8/pt not_active IP Right Cessation
- 2005-03-23 AR ARP050101174A patent/AR048191A1/es active IP Right Grant
-
2006
- 2006-09-11 ZA ZA200607575A patent/ZA200607575B/xx unknown
- 2006-09-17 IL IL178140A patent/IL178140A/en active IP Right Grant
- 2006-10-23 NO NO20064815A patent/NO338055B1/no active Protection Beyond IP Right Term
-
2009
- 2009-10-14 US US12/578,995 patent/US7744892B2/en not_active Expired - Lifetime
-
2010
- 2010-07-26 CY CY20101100698T patent/CY1110349T1/el unknown
-
2015
- 2015-11-30 NL NL300777C patent/NL300777I1/nl unknown
- 2015-12-02 HU HUS1500062C patent/HUS1500062I1/hu unknown
- 2015-12-04 FR FR15C0085C patent/FR15C0085I2/fr active Active
- 2015-12-07 CY CY2015052C patent/CY2015052I2/el unknown
- 2015-12-08 LT LTPA2015050D patent/LTPA2015050I1/lt unknown
- 2015-12-08 LT LTPA2015050C patent/LTC1730175I2/lt unknown
- 2015-12-08 LU LU92903C patent/LU92903I2/xx unknown
- 2015-12-09 BE BE2015C066C patent/BE2015C066I2/nl unknown
-
2017
- 2017-01-20 NO NO2017005C patent/NO2017005I1/no unknown
-
2022
- 2022-11-30 NO NO2022050C patent/NO2022050I1/no unknown