AU782142B2 - Mutant ERalpha and test systems for transactivation - Google Patents

Mutant ERalpha and test systems for transactivation Download PDF

Info

Publication number
AU782142B2
AU782142B2 AU18868/01A AU1886801A AU782142B2 AU 782142 B2 AU782142 B2 AU 782142B2 AU 18868/01 A AU18868/01 A AU 18868/01A AU 1886801 A AU1886801 A AU 1886801A AU 782142 B2 AU782142 B2 AU 782142B2
Authority
AU
Australia
Prior art keywords
era
seq
test
reporter gene
mutant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU18868/01A
Other languages
English (en)
Other versions
AU1886801A (en
Inventor
Norihisa Ohe
Koichi Saito
Hideo Satoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of AU1886801A publication Critical patent/AU1886801A/en
Application granted granted Critical
Publication of AU782142B2 publication Critical patent/AU782142B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Mushroom Cultivation (AREA)
AU18868/01A 1999-12-07 2000-12-01 Mutant ERalpha and test systems for transactivation Ceased AU782142B2 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
JP34802299 1999-12-07
JP11/348022 1999-12-07
JP37066799 1999-12-27
JP11/370667 1999-12-27
JP2000-207011 2000-07-07
JP2000207011 2000-07-07
JP2000-220508 2000-07-21
JP2000220508 2000-07-21
JP2000234053 2000-08-02
JP2000-234053 2000-08-02
JP2000235463 2000-08-03
JP2000235461 2000-08-03
JP2000235460 2000-08-03
JP2000-235460 2000-08-03
JP2000-235461 2000-08-03
JP2000-235463 2000-08-03
PCT/JP2000/008553 WO2001042307A1 (en) 1999-12-07 2000-12-01 MUTANT ERα AND TEST SYSTEMS FOR TRANSACTIVATION

Publications (2)

Publication Number Publication Date
AU1886801A AU1886801A (en) 2001-06-18
AU782142B2 true AU782142B2 (en) 2005-07-07

Family

ID=27573667

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18868/01A Ceased AU782142B2 (en) 1999-12-07 2000-12-01 Mutant ERalpha and test systems for transactivation

Country Status (8)

Country Link
US (1) US7582476B2 (https=)
EP (1) EP1237925B1 (https=)
JP (1) JP4742483B2 (https=)
AT (1) ATE366745T1 (https=)
AU (1) AU782142B2 (https=)
CA (1) CA2393045A1 (https=)
DE (1) DE60035522T2 (https=)
WO (1) WO2001042307A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057283A1 (en) * 2001-01-19 2002-07-25 Baylor College Of Medecine Methods and compositions in breast cancer diagnosis and therapeutics
CA2491417A1 (en) * 2002-07-02 2004-01-15 Yamanouchi Pharmaceutical Co., Ltd. Method for screening an agent for improving insulin resistance
CA2868618C (en) * 2002-10-16 2017-05-23 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
AU2003280793A1 (en) * 2002-11-15 2004-06-15 Sumitomo Chemical Company, Limited MUTANT ESTROGEN RECEPTOR-Alpha AND GENE THEREOF
CA2543329A1 (en) * 2003-10-24 2005-05-06 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa Orthogonal gene switches
FR2863275B1 (fr) * 2003-12-09 2007-08-10 Biomerieux Sa Procede pour le diagnostic/pronostic du cancer du sein
US20050164271A1 (en) 2004-01-20 2005-07-28 Sanjay Bhanot Modulation of glucocorticoid receptor expression
JP2006153656A (ja) * 2004-11-29 2006-06-15 Olympus Corp 反応カプセル、反応カプセルを使用した検査方法およびシステム
JP2015501155A (ja) 2011-10-25 2015-01-15 アイシス ファーマシューティカルズ, インコーポレーテッド Gccr発現のアンチセンス調整
BR112015030595A2 (pt) 2013-06-19 2017-07-25 Seragon Pharmaceuticals Inc moduladores de receptor de estrogênio de azetidina e usos dos mesmos
EA031077B1 (ru) 2013-06-19 2018-11-30 Серагон Фармасьютикалз, Инк. Модулятор рецептора эстрогена и его применения
CA2941161A1 (en) * 2014-03-13 2015-09-17 F.Hoffmann-La Roche Ag Methods and compositions for modulating estrogen receptor mutants
EP3303326B1 (en) 2015-05-26 2020-12-16 H. Hoffnabb-La Roche Ag Heterocyclic estrogen receptor modulators and uses thereof
US10179676B1 (en) 2017-07-26 2019-01-15 William Hagan Taylor Dispenser with self-closing cap

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987005049A1 (en) 1986-02-20 1987-08-27 California Biotechnology Inc. Eucaryotic expression of steroid receptor proteins
FR2634495B1 (fr) * 1988-07-01 1990-10-26 Chambon Pierre Procede de preparation d'une proteine par des levures utilisant un systeme inductible, vecteurs et souches transformees correspondantes
JPH06510363A (ja) * 1990-10-29 1994-11-17 ディカルブ プラント ジェネティクス 磁気性粒子を使用する生物学的材料の単離

Also Published As

Publication number Publication date
CA2393045A1 (en) 2001-06-14
JP4742483B2 (ja) 2011-08-10
DE60035522T2 (de) 2008-03-20
JP2003516137A (ja) 2003-05-13
AU1886801A (en) 2001-06-18
EP1237925B1 (en) 2007-07-11
EP1237925A1 (en) 2002-09-11
DE60035522D1 (de) 2007-08-23
WO2001042307A1 (en) 2001-06-14
US7582476B2 (en) 2009-09-01
ATE366745T1 (de) 2007-08-15
US20030207380A1 (en) 2003-11-06

Similar Documents

Publication Publication Date Title
AU782142B2 (en) Mutant ERalpha and test systems for transactivation
US6268221B1 (en) Melanocyte stimulating hormone receptor and uses
US20040171114A1 (en) Isolation and use of ryanodine receptors
HU221411B1 (en) Novel estrogen receptor
US5972643A (en) Isolated polynucleotide molecules encoding CTCF, a CCCTC-binding factor
KR100828506B1 (ko) 마우스 정자 형성 유전자와 인간 남성 불임 관련 유전자,및 이들을 사용한 진단 시스템
US6046011A (en) Mammalian adrenocorticotropic hormone receptors and uses
EP1218412A2 (en) Human g-protein coupled receptor
JP4400183B2 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
JP4400182B2 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
JP4400181B2 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
AU2476301A (en) DB the receptor for leptin nucleic acids encoding the receptor, and uses thereof
AU718702B2 (en) Mammalian melanocyte stimulating hormone receptors and uses
WO2004046352A1 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
JP2004008141A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP2004254600A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JPWO2006046331A1 (ja) ヒトK−ras遺伝子転写抑制剤
JP2004008140A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
CTCF et al. Lobanenkov et al.
JP2001521392A (ja) 新規なヒト腫瘍抑制遺伝子
JP2004254601A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP2002153280A (ja) Dnaとdna結合因子との結合を促進するタンパク質およびそのタンパク質をコードする遺伝子
JP2004254602A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP2004008142A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
WO1997047172A1 (en) Vitamin d receptor isoform protein