AU769571B2 - Polyionic coatings in analytic and sensor devices - Google Patents

Polyionic coatings in analytic and sensor devices Download PDF

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Publication number
AU769571B2
AU769571B2 AU46846/00A AU4684600A AU769571B2 AU 769571 B2 AU769571 B2 AU 769571B2 AU 46846/00 A AU46846/00 A AU 46846/00A AU 4684600 A AU4684600 A AU 4684600A AU 769571 B2 AU769571 B2 AU 769571B2
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AU
Australia
Prior art keywords
peg
pll
substrate
functionalized
adsorption
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU46846/00A
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English (en)
Other versions
AU4684600A (en
Inventor
Donald L. Elbert
Stephanie Finken
Rolf Hofer
Jeffrey A. Hubbell
Laurence Ruiz-Taylor
Nicholas D. Spencer
Marcus Textor
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Zurich Universität
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ETH Zurich
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Publication date
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Publication of AU769571B2 publication Critical patent/AU769571B2/en
Assigned to EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH reassignment EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH Alteration of Name(s) in Register under S187 Assignors: EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH, HUBBELL, JEFFREY A.
Assigned to UNIVERSITAT ZURICH reassignment UNIVERSITAT ZURICH Alteration of Name(s) in Register under S187 Assignors: EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Composite Materials (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
AU46846/00A 1999-04-28 2000-04-28 Polyionic coatings in analytic and sensor devices Expired AU769571B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13140299P 1999-04-28 1999-04-28
US13139199P 1999-04-28 1999-04-28
US60/131391 1999-04-28
US60/131402 1999-04-28
US18461600P 2000-02-24 2000-02-24
US60/184616 2000-02-24
PCT/US2000/011708 WO2000065352A1 (en) 1999-04-28 2000-04-28 Polyionic coatings in analytic and sensor devices

Publications (2)

Publication Number Publication Date
AU4684600A AU4684600A (en) 2000-11-10
AU769571B2 true AU769571B2 (en) 2004-01-29

Family

ID=27384152

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46846/00A Expired AU769571B2 (en) 1999-04-28 2000-04-28 Polyionic coatings in analytic and sensor devices

Country Status (8)

Country Link
US (1) US6884628B2 (enExample)
EP (1) EP1190252B1 (enExample)
JP (1) JP4647792B2 (enExample)
AT (1) ATE419528T1 (enExample)
AU (1) AU769571B2 (enExample)
CA (1) CA2371011C (enExample)
DE (1) DE60041255D1 (enExample)
WO (1) WO2000065352A1 (enExample)

Families Citing this family (245)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
DE60027309T2 (de) 1999-07-02 2006-08-31 Symyx Technologies, Inc., Santa Clara Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen
US20030059809A1 (en) * 1999-12-17 2003-03-27 Todor Vujasinovic Biochips,preparation and uses
US7163712B2 (en) * 2000-03-03 2007-01-16 Duke University Microstamping activated polymer surfaces
US6406777B1 (en) * 2000-06-14 2002-06-18 The United States Of America As Represented By The Secretary Of The Navy Metal and glass structure for use in surface enhanced Raman spectroscopy and method for fabricating same
DE10036907B4 (de) * 2000-07-28 2012-03-22 Xantec Bioanalytics Gmbh Verfahren zur Herstellung einer Beschichtung auf einem mit Gold bedampften Glassubstrat, Beschichtung hergestellt nach diesem Verfahren und deren Verwendung
US7678539B2 (en) * 2000-08-10 2010-03-16 Corning Incorporated Arrays of biological membranes and methods and use thereof
JP4887530B2 (ja) * 2000-08-21 2012-02-29 独立行政法人産業技術総合研究所 磁性微粒子、およびその製造方法
US7205161B2 (en) 2001-01-10 2007-04-17 Symyx Technologies, Inc. Polymer brushes for immobilizing molecules to a surface or substrate having improved stability
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
WO2002073158A2 (en) 2001-03-09 2002-09-19 Apollo Biotechnology, Inc. Conjugate probes and optical detection of analytes
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US6844028B2 (en) 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US7501157B2 (en) * 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US6989267B2 (en) 2001-07-02 2006-01-24 Agilent Technologies, Inc. Methods of making microarrays with substrate surfaces having covalently bound polyelectrolyte films
EP1411816A4 (en) * 2001-07-09 2005-09-28 Univ Arizona State AFFINITY BIOSENSOR FOR MONITORING BIOLOGICAL PROCESSES
AU2002338007A1 (en) * 2001-08-27 2003-03-18 Zeptosens Ag Surface for the immobilisation of nucleic acids
US20040253596A1 (en) * 2001-08-27 2004-12-16 Michael Pawlak Bioanalytical recognition surface with optimized recognition element density
US9671396B2 (en) * 2001-09-05 2017-06-06 Joon Won Park Solid substrate comprising array of dendrons and methods for using the same
EP1425583A1 (en) * 2001-09-12 2004-06-09 Eidgenössische Technische Hochschule Zürich Device with chemical surface patterns
EP1435520A4 (en) * 2001-09-21 2005-02-02 Takara Bio Inc SUPPORT FOR THE IMMOBILIZATION OF LIGANDS
FI118061B (fi) 2001-09-24 2007-06-15 Beanor Oy Menetelmä ja bioanturi analyysiä varten
DE60214118T2 (de) * 2001-12-21 2007-03-01 Interuniversitair Micro-Elektronica Centrum Verfahren zum Nachweis eines Analyten
CA2477563A1 (en) * 2001-12-21 2003-07-03 Sense Proteomic Limited Probe for mass spectrometry
US8043868B2 (en) * 2001-12-21 2011-10-25 Imec Method and apparatus for detecting an analyte
FI115166B (fi) 2001-12-31 2005-03-15 Biofons Oy Diagnostisia menetelmiä
AU2003219922B2 (en) * 2002-02-27 2009-09-10 Pharmain Corporation Compositions for delivery of therapeutics and other materials, and methods of making and using the same
US20050260259A1 (en) * 2004-04-23 2005-11-24 Bolotin Elijah M Compositions for treatment with glucagon-like peptide, and methods of making and using the same
US7635463B2 (en) * 2002-02-27 2009-12-22 Pharmain Corporation Compositions for delivery of therapeutics and other materials
WO2003072156A1 (en) * 2002-02-28 2003-09-04 Eidgenössische Technische Hochschule Zürich Oberflächentechnik Biomedical implant surfaces with osteogenic properties
US20050158848A1 (en) * 2002-04-12 2005-07-21 Ulrich Sieben Method for immobolizing molecules on surfaces
US7514150B2 (en) 2002-04-16 2009-04-07 Eidgenossische Technische Hochschule Zurich Environmentally compatible additives for aqueous lubricants
US20030198967A1 (en) * 2002-04-23 2003-10-23 Matson Robert S. Multi-functional microarrays and methods
US7010182B2 (en) * 2002-07-31 2006-03-07 Luna Innovations Incorporated Biosensors having enhanced environmental sensitivity
US7998699B2 (en) 2002-08-15 2011-08-16 University Of South Florida Early detection of pathogens in blood
US7384742B2 (en) * 2002-08-16 2008-06-10 Decision Biomarkers, Inc. Substrates for isolating reacting and microscopically analyzing materials
US20090118605A1 (en) * 2002-08-30 2009-05-07 Northwestern University Surface-enhanced raman nanobiosensor
US20040043508A1 (en) * 2002-09-03 2004-03-04 Frutos Anthony G. Polymer-coated substrates for binding biological molecules
US20040062882A1 (en) * 2002-09-30 2004-04-01 Andrea Liebmann-Vinson Cell adhesion resisting surfaces
ES2208121B1 (es) * 2002-11-29 2005-08-16 Consejo Sup. Investig. Cientificas Anticuerpos y antigenos inmovilizados sobre particulas magneticas de silice como biosensores.
US7070922B2 (en) * 2002-12-04 2006-07-04 International Business Machines Corporation Surface treatment
US20040121339A1 (en) * 2002-12-19 2004-06-24 Jizhong Zhou Special film-coated substrate for bio-microarray fabrication and use thereof
CN100347545C (zh) * 2003-04-08 2007-11-07 成都夸常科技有限公司 一种对样品中的目标物进行定性和/或定量分析的方法及其检测装置
JP4006523B2 (ja) * 2003-04-10 2007-11-14 独立行政法人産業技術総合研究所 タンパク質アレイ及びその作製方法
AU2004230592B2 (en) * 2003-04-14 2007-10-04 Caliper Life Sciences, Inc. Reduction of migration shift assay interference
DE10320312A1 (de) * 2003-05-06 2004-12-02 Friz Biochem Gmbh Substrat als Träger von Ligaten
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US7160867B2 (en) * 2003-05-16 2007-01-09 Isotechnika, Inc. Rapamycin carbohydrate derivatives
EP1654066B1 (en) 2003-07-31 2014-11-12 Handylab, Inc. Processing particle-containing samples
US9206414B2 (en) * 2003-08-13 2015-12-08 Axcelon Biopolymers Corporation Anisotropic nanocomposite hydrogel
PT2103694E (pt) 2003-08-15 2011-07-26 Univ South Florida Materiais e métodos para a captura de patogénios e a remoção de ácido aurintricarboxílico de uma amostra
US20050070027A1 (en) * 2003-09-30 2005-03-31 Jacques Gollier Double resonance interrogation of grating-coupled waveguides
JP2006514299A (ja) * 2003-10-27 2006-04-27 センス プロテオミック リミテッド 酵素アレイ及びアッセイ
WO2005051905A2 (en) * 2003-11-19 2005-06-09 Massachusetts Institute Of Technology Large-area two-dimensional non-adhesive cell arrays for sensing and cell-sorting applications
US7510942B2 (en) * 2003-11-25 2009-03-31 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Molecular modifications of metal/dielectric interfaces
US20050131513A1 (en) * 2003-12-16 2005-06-16 Cook Incorporated Stent catheter with a permanently affixed conductor
US20050180957A1 (en) * 2004-01-16 2005-08-18 Scharp David W. Method of using fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells
US7723126B2 (en) * 2004-03-24 2010-05-25 Wisconsin Alumni Research Foundation Plasma-enhanced functionalization of inorganic oxide surfaces
JP4535490B2 (ja) * 2004-04-09 2010-09-01 株式会社資生堂 蛋白質吸着防止方法
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
EP2345739B8 (en) 2004-05-03 2016-12-07 Handylab, Inc. A microfluidic device for processing polynucleotide-containing samples
WO2005114194A1 (en) * 2004-05-21 2005-12-01 Mds Inc. Doing Business Through Its Mds Pharma Services Division Method of quantifying the cell-binding properties of a medical device
US7572766B2 (en) * 2004-06-16 2009-08-11 Affinergy, Inc. IFBMs to promote the specific attachment of target analytes to the surface of orthopedic implants
US10150945B2 (en) * 2004-07-23 2018-12-11 Jnc Corporation Cell culture device and manufacturing method therof
CN101010588A (zh) * 2004-08-04 2007-08-01 爱克瑟拉生物传感器有限公司 用在基于衍射的传感中的利用化学交联剂图案化的表面
US7595157B2 (en) * 2004-08-19 2009-09-29 Biocept, Inc. Microarrays utilizing hydrogels
ATE541821T1 (de) * 2004-10-12 2012-02-15 Schott Ag Gemultiplexter proteinadsorptions-assay
US20060110594A1 (en) * 2004-11-24 2006-05-25 Frutos Anthony G Polymer-coated substrates for binding biomolecules and methods of making and using thereof
WO2006070841A1 (ja) * 2004-12-28 2006-07-06 Japan Science And Technology Agency 自己組織化材料または微粒子を基板上に固定化する方法、および当該方法を用いて作製した基板
US7629173B2 (en) * 2004-12-29 2009-12-08 Corning Incorporated Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors
US20060141527A1 (en) * 2004-12-29 2006-06-29 Caracci Stephen J Method for creating a reference region and a sample region on a biosensor and the resulting biosensor
US7604984B2 (en) * 2004-12-29 2009-10-20 Corning Incorporated Spatially scanned optical reader system and method for using same
JP2006335912A (ja) * 2005-06-03 2006-12-14 Fujifilm Holdings Corp 生理活性物質固定化剤
EP1696235B1 (en) * 2005-02-23 2009-10-28 FUJIFILM Corporation Biosensor
US8465771B2 (en) * 2005-03-30 2013-06-18 The University Of Western Ontario Anisotropic hydrogels
JP2006271860A (ja) * 2005-03-30 2006-10-12 Japan Lifeline Co Ltd 医療用具及びその製造方法
WO2006113785A2 (en) * 2005-04-18 2006-10-26 Brigham Young University Laser modification and functionalization of substrates
EP1877773B1 (de) 2005-04-26 2014-10-15 Bayer Intellectual Property GmbH Neue apparatur und verfahren zur beschichtung von trägersubstraten für einen analytnachweis mittels affinitäts-nachweisverfahren
US7723438B2 (en) * 2005-04-28 2010-05-25 International Business Machines Corporation Surface-decorated polymeric amphiphile porogens for the templation of nanoporous materials
US20070009568A1 (en) * 2005-06-03 2007-01-11 Bhatnagar Rajendra S Methods for immobilizing molecules on surfaces
US8475886B2 (en) 2005-08-05 2013-07-02 Corning Incorporated Methods for producing surfaces that resist non-specific protein binding and cell attachment
WO2007035527A2 (en) * 2005-09-15 2007-03-29 Duke University Non-fouling polymeric surface modification and signal amplification method for biomolecular detection
US7763423B2 (en) * 2005-09-30 2010-07-27 Pacific Biosciences Of California, Inc. Substrates having low density reactive groups for monitoring enzyme activity
JP4818056B2 (ja) * 2005-10-07 2011-11-16 キヤノン株式会社 標的物質を捕捉する捕捉分子を結合させるための結合用官能基を基体上に備えた構造体
US20090148346A1 (en) * 2005-10-07 2009-06-11 Canon Kabushiki Kaisha Substrate with binding functional group
WO2007053561A2 (en) * 2005-11-01 2007-05-10 Rensselaer Polytechnic Institute Three-dimensional cellular array chip and platform for toxicology assays
US20070117152A1 (en) * 2005-11-08 2007-05-24 Fujifilm Corporation Biosensor
US8334140B2 (en) * 2005-11-08 2012-12-18 Smart Holograms Limited Boronate complex and its use in a glucose sensor
US20070224164A1 (en) * 2005-11-14 2007-09-27 Maciej Radosz Degradable nanogel for drug delivery
US20070110786A1 (en) * 2005-11-15 2007-05-17 Boston Scientific Scimed, Inc. Medical articles having enhanced therapeutic agent binding
WO2007059514A2 (en) * 2005-11-15 2007-05-24 Oxonica, Inc. Sers-based methods for detection of bioagents
KR100738083B1 (ko) * 2005-12-20 2007-07-12 삼성전자주식회사 마이크로어레이용 기판 및 그의 제조방법
US7674864B2 (en) * 2005-12-23 2010-03-09 Boston Scientific Scimed, Inc. Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods
US8455088B2 (en) 2005-12-23 2013-06-04 Boston Scientific Scimed, Inc. Spun nanofiber, medical devices, and methods
US7723422B2 (en) * 2005-12-23 2010-05-25 Boston Scientific Scimed, Inc. Functionalized block copolymers
US7781203B2 (en) 2005-12-29 2010-08-24 Corning Incorporated Supports for assaying analytes and methods of making and using thereof
US8834912B2 (en) * 2005-12-30 2014-09-16 Boston Scientific Scimed, Inc. Medical devices having multiple charged layers
EP1808187A1 (en) * 2006-01-11 2007-07-18 Straumann Holding AG Cell selective implant surface with controlled release of bioactive agents
JP2009524834A (ja) * 2006-01-27 2009-07-02 オクソニカ・インコーポレーテッド 被包検出様式を用いた側方流動イムノアッセイ
CA2638038A1 (en) * 2006-02-28 2007-09-07 Tyco Healthcare Group Lp Tissue adhesives and sealants comprising biotin and avidin polymers
US8349349B2 (en) * 2006-02-28 2013-01-08 Covidien Lp Tissue adhesives and sealants and method for their use
US8835513B2 (en) 2006-02-28 2014-09-16 Covidien Lp Drug delivery devices
EP1997877B1 (en) * 2006-03-17 2014-03-05 Sanyo Chemical Industries, Ltd. Cell culture substrate
US20100111917A1 (en) * 2006-03-21 2010-05-06 Ying Jackie Y Cell-adhesive polyelectrolyte material for use as membrane and coating
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US9040288B2 (en) 2006-03-24 2015-05-26 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using the same
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8545865B2 (en) * 2006-03-24 2013-10-01 Boston Scientific Scimed, Inc. Medical devices having polymer brushes
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
US20080050747A1 (en) * 2006-03-30 2008-02-28 Pacific Biosciences Of California, Inc. Articles having localized molecules disposed thereon and methods of producing and using same
US20080076189A1 (en) * 2006-03-30 2008-03-27 Visigen Biotechnologies, Inc. Modified surfaces for the detection of biomolecules at the single molecule level
US8975216B2 (en) * 2006-03-30 2015-03-10 Pacific Biosciences Of California Articles having localized molecules disposed thereon and methods of producing same
WO2007118714A1 (en) * 2006-04-19 2007-10-25 Universiteit Gent Integrated surface mode biosensor
US8330951B2 (en) * 2006-04-28 2012-12-11 Hewlett-Packard Development Company, L.P. Nano-enhanced Raman spectroscopy substrate packaging structure
US9790538B2 (en) 2013-03-07 2017-10-17 Apdn (B.V.I.) Inc. Alkaline activation for immobilization of DNA taggants
US10741034B2 (en) 2006-05-19 2020-08-11 Apdn (B.V.I.) Inc. Security system and method of marking an inventory item and/or person in the vicinity
JP5277165B2 (ja) * 2006-07-24 2013-08-28 ベクトン・ディキンソン・アンド・カンパニー 分析粒子凝集およびイメージング装置および方法
WO2008019381A1 (en) * 2006-08-07 2008-02-14 University Of Washington Mixed charge copolymers and hydrogels
US20100137155A1 (en) * 2006-08-08 2010-06-03 Sharp Kabuchiki Kaisha Biosensor, method for fabricating the same, detecting method utilizing the same
JP5001015B2 (ja) * 2006-09-28 2012-08-15 富士フイルム株式会社 非特異吸着を抑制した表面を有する生化学用器具
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
JP2010510247A (ja) * 2006-11-21 2010-04-02 アプライド バイオシステムズ インコーポレイテッド 酸化物層上に不動態化表面を形成するための中間体および方法およびこれにより製造される製品
US8029902B2 (en) * 2006-12-11 2011-10-04 Wisconsin Alumni Research Foundation Plasma-enhanced functionalization of substrate surfaces with quaternary ammonium and quaternary phosphonium groups
CA2674632A1 (en) * 2006-12-29 2008-07-10 University Of Washington Dual-functional nonfouling surfaces and materials
JP2008185494A (ja) * 2007-01-31 2008-08-14 Fujifilm Corp 生理活性物質固定化基板
EP2076774A1 (en) * 2007-02-28 2009-07-08 Corning Incorporated Surfaces and methods for biosensor cellular assays
JP2008249502A (ja) * 2007-03-30 2008-10-16 Fujifilm Corp 生理活性物質を固定化した固体基板
US8093039B2 (en) * 2007-04-10 2012-01-10 The Trustees Of The Stevens Institute Of Technology Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells
US8084077B2 (en) 2007-05-25 2011-12-27 Abbott Laboratories One-step phosphorylcholine-linked polymer coating and drug loading of stent
EP2165353B1 (en) 2007-06-29 2017-08-30 Applied Biosystems, LLC Systems and methods for electronic detection with nanofets
ES2648798T3 (es) 2007-07-13 2018-01-08 Handylab, Inc. Materiales de captura de polinucleótidos y métodos de utilización de los mismos
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US7960336B2 (en) * 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
US20100292427A1 (en) * 2007-08-06 2010-11-18 Canon Kabushiki Kaisha Structural member and method of producing the structural member
US8563527B2 (en) * 2007-08-20 2013-10-22 Pharmain Corporation Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same
WO2009031804A2 (en) * 2007-09-07 2009-03-12 Gwangju Institute Of Science And Technology Multi-functional polymeric layers and its uses
KR101050690B1 (ko) 2007-09-07 2011-07-20 광주과학기술원 다기능성 고분자막 및 그의 용도
WO2009039466A1 (en) 2007-09-20 2009-03-26 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
DE102007049013A1 (de) * 2007-10-11 2009-04-16 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Sensor mit Langzeitstabilität für Bio-Prozesse
US20090130746A1 (en) * 2007-10-25 2009-05-21 Canon U.S. Life Sciences, Inc. Microchannel surface coating
US20110092768A1 (en) * 2007-10-31 2011-04-21 Given Imaging Ltd. Device, system and method for in-vivo analysis
JP5345335B2 (ja) * 2007-12-03 2013-11-20 国立大学法人九州大学 新規双性イオン型多分岐樹脂、並びに、蛋白質チップ表面調節剤
RU2010127266A (ru) 2007-12-05 2012-01-10 Зиомикс, Инк. (Us) Набор для анализа клеток и способ
US8796184B2 (en) 2008-03-28 2014-08-05 Sentilus, Inc. Detection assay devices and methods of making and using the same
US8815611B2 (en) 2008-04-10 2014-08-26 Corning Incorporated Surface for label independent detection and method thereof
US8877298B2 (en) * 2008-05-27 2014-11-04 The Hong Kong University Of Science And Technology Printing using a structure coated with ultraviolet radiation responsive material
JP2009286968A (ja) * 2008-05-30 2009-12-10 Canon Inc グラフトポリマー含有基体、その製造方法および磁気バイオセンサ
US20090311540A1 (en) * 2008-06-11 2009-12-17 Yoram Cohen Highly Sensitive and Selective Nano-Structured Grafted Polymer Layers
WO2010004568A1 (en) * 2008-07-10 2010-01-14 Given Imaging Ltd. Device, method and kit for in vivo detection of a biomarker
WO2010005444A1 (en) * 2008-07-11 2010-01-14 Handylab, Inc. Polynucleotide capture materials, and methods of using same
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US8173198B2 (en) * 2008-07-23 2012-05-08 Life Technologies Corporation Deposition of metal oxides onto surfaces as an immobilization vehicle for carboxylated or phophated particles or polymers
US20100034704A1 (en) * 2008-08-06 2010-02-11 Honeywell International Inc. Microfluidic cartridge channel with reduced bubble formation
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
WO2010039247A2 (en) * 2008-10-03 2010-04-08 Molecular Sensing, Inc. Substrates with surfaces modified with peg
DE102008053270A1 (de) 2008-10-27 2010-05-12 Medizinische Hochschule Hannover Vorrichtung und Verfahren zur Analyse von Zellen
US8580240B1 (en) 2008-11-19 2013-11-12 University Of Kentucky Research Foundation Compounds and methods for reducing the occurrence of post-surgical adhesions
EP2373355A4 (en) * 2008-11-25 2013-10-02 Univ California FUNCTIONALIZED TITANIUM IMPLANTS AND RELATED REGENERATIVE MATERIALS
EP2192410B1 (en) * 2008-11-26 2012-07-11 Corning Incorporated Nanoparticulate affininty capture for label independent detections system
EP2204650B1 (en) * 2008-12-31 2012-06-27 DWI an der RWTH Aachen e.V. Novel biosensor system based on recognition induced birefringence (RIB)
WO2010080710A2 (en) * 2009-01-12 2010-07-15 Molecular Sensing, Inc. Sample collection and measurement in a single container by back scattering interferometry
EP2409153B1 (en) * 2009-03-20 2014-05-14 Attana AB Method of detecting ligand binding making use of a mass-sensitive sensor comprising immobilised cells on its surface
US8505743B2 (en) * 2009-04-08 2013-08-13 Michigan Molecular Institute Surface modification of polyamide reverse osmosis membranes
WO2010123448A1 (en) * 2009-04-21 2010-10-28 Gyros Patent Ab Method for reducing adsorption losses on metal oxide surfaces
EP2424971A4 (en) * 2009-05-01 2013-07-31 Univ Utah Res Found METHOD AND COMPOSITIONS FOR MEASURING HIGH AFFAIR INTERACTIONS WITH KINETIC IMAGING OF A SINGLE MOLECULAR ACTION (KISMI)
US8501406B1 (en) 2009-07-14 2013-08-06 Pacific Biosciences Of California, Inc. Selectively functionalized arrays
WO2011028358A2 (en) * 2009-09-02 2011-03-10 Mayo Foundation For Medical Education And Research System and method for detecting healing adjacent to implanted medical device
US20110225809A1 (en) * 2010-03-17 2011-09-22 Alan Francis Daher Apparatus for removably attaching an item to a surface
WO2011119536A1 (en) 2010-03-22 2011-09-29 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US9482664B2 (en) * 2010-05-17 2016-11-01 Sentilus Holdco LLC Detection devices and related methods of use
WO2011156713A1 (en) 2010-06-11 2011-12-15 Vanderbilt University Multiplexed interferometric detection system and method
EP2409766A1 (de) * 2010-07-23 2012-01-25 F. Hoffmann-La Roche AG Verfahren zur Hydrophilisierung von Oberflächen fluidischer Komponenten und derartige Komponenten enthaltende Bauteile
US9562853B2 (en) 2011-02-22 2017-02-07 Vanderbilt University Nonaqueous backscattering interferometric methods
CN106190806B (zh) 2011-04-15 2018-11-06 贝克顿·迪金森公司 扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法
EP2541250A1 (en) 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Molecular architecture on magnetic particles for affinity assays with low non-specific binding
JP5564155B1 (ja) * 2011-07-13 2014-07-30 エンパイア テクノロジー ディベロップメント エルエルシー 再生可能な表面を伴う、表面プラズモンを用いる検体監視のための方法およびシステム
EP2731429A4 (en) * 2011-07-15 2015-03-04 Univ Georgia COMPOUNDS, METHOD OF MANUFACTURING THEREFOR AND USE METHOD THEREFOR
US9599613B2 (en) 2011-07-20 2017-03-21 University Of Washington Through Its Center For Commercialization Photonic blood typing
DK2761305T3 (da) 2011-09-30 2017-11-20 Becton Dickinson Co Forenet reagensstrimmel
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
US9518986B2 (en) 2011-11-02 2016-12-13 University Of Cape Town Method of detecting and/or quantifying an analyte in a biological sample
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
US10031138B2 (en) * 2012-01-20 2018-07-24 University Of Washington Through Its Center For Commercialization Hierarchical films having ultra low fouling and high recognition element loading properties
DK2810080T3 (da) 2012-02-03 2024-06-17 Becton Dickinson Co Eksterne filer til fordeling af molekylære diagnostiske tests og bestemmelse af kompatabilitet imellem tests
US9572580B2 (en) 2012-03-16 2017-02-21 Covidien Lp Closure tape dispenser
US9161756B2 (en) 2012-03-16 2015-10-20 Covidien Lp Closure tape dispenser
JP5844195B2 (ja) * 2012-03-29 2016-01-13 三洋化成工業株式会社 磁性シリカ粒子並びにこれを用いた免疫測定法及び免疫測定用試薬
US20140102899A1 (en) * 2012-04-09 2014-04-17 Applied Dna Sciences, Inc. Plasma treatment for dna binding
US9273949B2 (en) 2012-05-11 2016-03-01 Vanderbilt University Backscattering interferometric methods
EP2875078B1 (en) * 2012-07-18 2017-12-20 President and Fellows of Harvard College Modification of surfaces for simulataneous repellency and targeted binding of desired moieties
US9758606B2 (en) 2012-07-31 2017-09-12 The Trustees Of Columbia University In The City Of New York Cyclopropenium polymers and methods for making the same
WO2014022365A1 (en) * 2012-07-31 2014-02-06 The Trustees Of Columbia University In The City Of New York Cyclopropenium polymers and methods for making the same
US9266370B2 (en) 2012-10-10 2016-02-23 Apdn (B.V.I) Inc. DNA marking of previously undistinguished items for traceability
US9297032B2 (en) 2012-10-10 2016-03-29 Apdn (B.V.I.) Inc. Use of perturbants to facilitate incorporation and recovery of taggants from polymerized coatings
US8994077B2 (en) * 2012-12-21 2015-03-31 International Business Machines Corporation Field effect transistor-based bio sensor
TWI535750B (zh) 2013-01-14 2016-06-01 國立臺灣大學 基材上的聚合物組成物以及表面改質方法
WO2014171597A1 (ko) 2013-04-15 2014-10-23 (주)플렉센스 나노 입자 어레이의 제조 방법, 표면 플라즈몬 공명 기반의 센서, 및 이를 이용한 분석 방법
US10060851B2 (en) * 2013-03-05 2018-08-28 Plexense, Inc. Surface plasmon detection apparatuses and methods
US9963740B2 (en) 2013-03-07 2018-05-08 APDN (B.V.I.), Inc. Method and device for marking articles
US10544449B2 (en) 2013-06-14 2020-01-28 Pacific Biosciences Of California, Inc. Bis-biotinylation tags
DE102013211850A1 (de) * 2013-06-21 2014-12-24 Gilupi Gmbh Schnelltest zum Nachweisen von Erregermaterial, insbesondere zur Unterstützung der Diagnose einer Sepsis, sowie Kit und Vorrichtung zur Durchführung eines Sepsistests
DE102013211837A1 (de) * 2013-06-21 2014-12-24 Gilupi Gmbh Katheter mit Detektionsvorrichtung zum Echtzeitnachweis eines Probenmaterials
US9366651B2 (en) 2013-07-03 2016-06-14 Matrix Sensors, Inc. Array of sensors with surface modifications
EP3058339B1 (en) 2013-10-07 2019-05-22 APDN (B.V.I.) Inc. Multimode image and spectral reader
US10745825B2 (en) 2014-03-18 2020-08-18 Apdn (B.V.I.) Inc. Encrypted optical markers for security applications
CN106103121B (zh) 2014-03-18 2019-12-06 亚普蒂恩(B.V.I.)公司 用于安全应用的加密光学标记物
WO2016004244A1 (en) 2014-07-02 2016-01-07 Life Technologies Corporation Surface treatment of semiconductor sensors
US11754563B2 (en) 2014-11-20 2023-09-12 Global Life Sciences Solutions Operations UK Ltd Porous membranes with a polymer grafting, methods and uses thereof
US10760182B2 (en) 2014-12-16 2020-09-01 Apdn (B.V.I.) Inc. Method and device for marking fibrous materials
WO2016118812A1 (en) 2015-01-23 2016-07-28 Vanderbilt University A robust interferometer and methods of using same
TWI585401B (zh) * 2015-12-17 2017-06-01 長庚大學 光定址電位感測元件
EP3408649B1 (en) 2016-01-29 2023-06-14 Vanderbilt University Free-solution response function interferometry
WO2017180302A1 (en) 2016-04-11 2017-10-19 Apdn (B.V.I.) Inc. Method of marking cellulosic products
US10995371B2 (en) 2016-10-13 2021-05-04 Apdn (B.V.I.) Inc. Composition and method of DNA marking elastomeric material
US9999899B2 (en) 2016-11-01 2018-06-19 International Business Machines Corporation Controlled exposure of in-vivo sensors
US10920274B2 (en) 2017-02-21 2021-02-16 Apdn (B.V.I.) Inc. Nucleic acid coated submicron particles for authentication
JP7356909B2 (ja) 2017-05-05 2023-10-05 クアンタム－エスアイ インコーポレイテッド 生物学的反応における表面反応性と防汚特性が改変された基板
WO2018222034A1 (en) * 2017-05-30 2018-12-06 Jurriaan Huskens Surface with poly-cationic polymers and functionalized using coupling chemistry, biosensor comprising the same and use thereof in bio-sensing
EP3642348A1 (en) * 2017-06-22 2020-04-29 Paris Sciences et Lettres - Quartier Latin Redox cleavable comb-like copolymer for controlled adhesion between cells and substrates
JP7358334B2 (ja) 2018-03-28 2023-10-10 持田製薬株式会社 新規反応性アルギン酸誘導体
WO2020027097A1 (ja) * 2018-07-31 2020-02-06 富士フイルム株式会社 固相担体およびキット
EP3938109A4 (en) * 2019-03-11 2023-07-19 Redbud Labs, Inc. METHODS OF SURFACE MODIFICATION OF SILICONES FOR SPECIFIC TARGET AND HIGH BONDING EFFICIENCY
US11357542B2 (en) 2019-06-21 2022-06-14 Covidien Lp Valve assembly and retainer for surgical access assembly
JP7692359B2 (ja) 2019-09-25 2025-06-13 持田製薬株式会社 新規な架橋アルギン酸構造体
CN114829669B (zh) 2019-10-11 2024-10-01 宽腾矽公司 气相表面改性
WO2021090787A1 (ja) * 2019-11-05 2021-05-14 国立大学法人東海国立大学機構 ポリペプチド
EP4058810A4 (en) * 2019-11-15 2023-12-20 President And Fellows Of Harvard College DEVICE AND METHOD FOR ANALYTE DETECTION
WO2023205353A1 (en) * 2022-04-21 2023-10-26 Ultima Genomics, Inc. Self assembly of beads on substrates
EP4299596A1 (en) * 2022-06-30 2024-01-03 betaSENSE GmbH Molecular probe functionalized element

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250613A (en) * 1990-10-22 1993-10-05 Berol Nobel Ab Solid surface coated with a hydrophilic outer layer with covalently bonded biopolymers, a method of making such a surface, and a conjugate therefor
WO1998047948A1 (en) * 1997-04-18 1998-10-29 California Institute Of Technology Multifunctional polymeric tissue coatings

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822867A (en) * 1987-02-02 1989-04-18 Semih Erhan Protein polymer grafts
US4886836A (en) * 1987-06-03 1989-12-12 Pall Corporation Activated medium with low non-specific protein adsorption
US5866322A (en) * 1988-01-29 1999-02-02 Abbott Laboratories Method for performing Rubella assay
DE68911181T2 (de) * 1988-03-31 1994-04-07 Grace W R & Co Mit Protein nichtabsorbierend polyureum-urethan-polymerbeschichtete Gegenstände.
JP2570408B2 (ja) * 1988-11-29 1997-01-08 東ソー株式会社 抗原，抗体又は生理活性物質固定化用の担体
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
US5459054A (en) * 1989-12-05 1995-10-17 Neocrin Company Cells encapsulated in alginate containing a high content of a- l- guluronic acid
US5380536A (en) * 1990-10-15 1995-01-10 The Board Of Regents, The University Of Texas System Biocompatible microcapsules
US5626863A (en) 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5462990A (en) 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US6093558A (en) * 1991-07-25 2000-07-25 Edge Biosystems, Inc. Binding protein of biologically active compositions to an adhesive formulation on a substrate
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
DE4208645A1 (de) * 1992-03-18 1993-09-23 Bayer Ag Optischer festphasenbiosensor auf basis fluoreszenzfarbstoffmarkierter polyionischer schichten
US5578442A (en) * 1992-03-23 1996-11-26 Vivorx, Inc. Graft copolymers of polycationic species and water-soluble polymers, and use therefor
US6113946A (en) * 1992-04-03 2000-09-05 The Regents Of The University Of California Self-assembling polynucleotide delivery system comprising dendrimer polycations
ATE154526T1 (de) * 1992-04-16 1997-07-15 Merck Patent Gmbh Aktivierte trägermaterialien, ihre herstellung und verwendung
AU4402793A (en) * 1992-05-29 1993-12-30 Regents Of The University Of California, The Coated transplant and method for making same
US5344455A (en) * 1992-10-30 1994-09-06 Medtronic, Inc. Graft polymer articles having bioactive surfaces
US5414075A (en) * 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
SE509662C2 (sv) * 1993-04-29 1999-02-22 Tetra Laval Holdings & Finance Förpackningslaminat belagt med en vattenolöslig chitosanförening samt sätt att tillverka förpackningslaminatet
WO1994027137A2 (en) * 1993-05-18 1994-11-24 University Of Utah Research Foundation Apparatus and methods for multianalyte homogeneous fluoroimmunoassays
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
US6284503B1 (en) * 1993-08-20 2001-09-04 University Of Utah Research Foundation Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
US5543326A (en) * 1994-03-04 1996-08-06 Heller; Adam Biosensor including chemically modified enzymes
BR9508139A (pt) * 1994-06-28 1999-11-30 Tri Point Medical Corp Processo, processo de regular uma velocidade de biodegradação in vivo de um polìmero e de unir entre si duas superfìcies in vivo, composição biocompatìvel, adesivo, vedante e implante cirúrgico e sistema de liberação para um agente terapêutico
US5840576A (en) * 1994-07-20 1998-11-24 Cytotherapeutics, Inc. Methods and compositions of growth control for cells encapsulated within bioartificial organs
US5507804A (en) * 1994-11-16 1996-04-16 Alcon Laboratories, Inc. Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US6017577A (en) * 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
US5629213A (en) * 1995-03-03 1997-05-13 Kornguth; Steven E. Analytical biosensor
DE19530078A1 (de) * 1995-08-16 1997-02-20 Bayer Ag Optischer Festphasenbiosensor auf Basis von Streptavidin und Biotin
US5916585A (en) * 1996-06-03 1999-06-29 Gore Enterprise Holdings, Inc. Materials and method for the immobilization of bioactive species onto biodegradable polymers
CN1173776C (zh) * 1996-06-28 2004-11-03 卡钳技术有限公司 在微规模流体性设备里的高通过量的筛选分析系统
CA2202424A1 (en) * 1997-04-11 1998-10-11 Donald E. Brooks A tethered polymer macromolecule-excluding surface, its mode of synthesis and use
US6287558B1 (en) * 1997-08-01 2001-09-11 Biohybrio Technologies Llc Devices containing cells or tissue and an agent that inhibits damage by a host cell molecule
US6121027A (en) * 1997-08-15 2000-09-19 Surmodics, Inc. Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups
US6348322B1 (en) * 1997-10-17 2002-02-19 Duke University Method of screening for specific binding interactions
US6235340B1 (en) * 1998-04-10 2001-05-22 Massachusetts Institute Of Technology Biopolymer-resistant coatings
US6303136B1 (en) * 1998-04-13 2001-10-16 Neurotech S.A. Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane
WO1999052560A1 (en) * 1998-04-13 1999-10-21 Massachusetts Institute Of Technology Comb copolymers for regulating cell-surface interactions
US6248127B1 (en) * 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
US6303179B1 (en) * 1999-02-08 2001-10-16 Medtronic, Inc Method for attachment of biomolecules to surfaces through amine-functional groups

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250613A (en) * 1990-10-22 1993-10-05 Berol Nobel Ab Solid surface coated with a hydrophilic outer layer with covalently bonded biopolymers, a method of making such a surface, and a conjugate therefor
WO1998047948A1 (en) * 1997-04-18 1998-10-29 California Institute Of Technology Multifunctional polymeric tissue coatings

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EP1190252A1 (en) 2002-03-27
CA2371011C (en) 2009-12-22
US20020128234A1 (en) 2002-09-12
EP1190252B1 (en) 2008-12-31
AU4684600A (en) 2000-11-10
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JP4647792B2 (ja) 2011-03-09
US6884628B2 (en) 2005-04-26

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