AU749749B2 - Mutant recombinant allergens - Google Patents

Mutant recombinant allergens Download PDF

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Publication number
AU749749B2
AU749749B2 AU27147/99A AU2714799A AU749749B2 AU 749749 B2 AU749749 B2 AU 749749B2 AU 27147/99 A AU27147/99 A AU 27147/99A AU 2714799 A AU2714799 A AU 2714799A AU 749749 B2 AU749749 B2 AU 749749B2
Authority
AU
Australia
Prior art keywords
allergen
recombinant
derived
amino acid
recombinant allergen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27147/99A
Other languages
English (en)
Other versions
AU2714799A (en
Inventor
Hans Henrik Ipsen
Jorgen Nedergaard Larsen
Michael Dho Spangfort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALK Abello AS
Original Assignee
ALK Abello AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8092687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU749749(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ALK Abello AS filed Critical ALK Abello AS
Publication of AU2714799A publication Critical patent/AU2714799A/en
Application granted granted Critical
Publication of AU749749B2 publication Critical patent/AU749749B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU27147/99A 1998-03-16 1999-03-16 Mutant recombinant allergens Ceased AU749749B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK364/98 1998-03-16
DK36498 1998-03-16
PCT/DK1999/000136 WO1999047680A1 (en) 1998-03-16 1999-03-16 Mutant recombinant allergens

Publications (2)

Publication Number Publication Date
AU2714799A AU2714799A (en) 1999-10-11
AU749749B2 true AU749749B2 (en) 2002-07-04

Family

ID=8092687

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27147/99A Ceased AU749749B2 (en) 1998-03-16 1999-03-16 Mutant recombinant allergens

Country Status (19)

Country Link
US (1) US20040091500A1 (enExample)
EP (1) EP1062341B1 (enExample)
JP (1) JP2002506648A (enExample)
KR (1) KR20010041918A (enExample)
CN (1) CN1332029C (enExample)
AT (1) ATE408690T1 (enExample)
AU (1) AU749749B2 (enExample)
CA (1) CA2323687C (enExample)
DE (1) DE69939584D1 (enExample)
DK (1) DK1062341T3 (enExample)
ES (1) ES2313776T3 (enExample)
HU (1) HUP0101464A3 (enExample)
IL (2) IL138339A0 (enExample)
NO (1) NO328354B1 (enExample)
NZ (1) NZ506665A (enExample)
PL (1) PL194804B1 (enExample)
PT (1) PT1062341E (enExample)
WO (1) WO1999047680A1 (enExample)
ZA (1) ZA200004819B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226770B2 (en) * 2000-04-28 2007-06-05 Novozymes A/S Lipolytic enzyme variant
IT1318690B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti dell'allergene maggiore par j 2 di parietaria judaica.
IT1318692B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti di proteine allergeniche di phleum pratense.
ATE403152T1 (de) * 2000-10-17 2008-08-15 Besst Test Aps Test zum direkten nachweisen einer biologischen zelle in einer körperflüssigkeitsprobe
PL214225B1 (pl) * 2000-11-16 2013-07-31 Alk Abello As Zrekombinowany alergen, zastosowanie zrekombinowanego alergenu, kompozycja farmaceutyczna, sposób przygotowania kompozycji farmaceutycznej, sposób przygotowania zrekombinowanego alergenu, sekwencja DNA kodujaca zrekombinowany alergen, wektor ekspresyjny, komórka gospodarza oraz sposób produkcji zrekombinowanego zmutowanego alergenu
DK1219300T3 (da) * 2000-12-28 2007-03-05 Biomay Prod & Handel Behandling af allergi
EP1499349B1 (en) * 2001-03-02 2009-11-18 The Rockefeller University Recombinant hybrid allergen constructs with reduced allergenicity that retain immunogenicity of the natural allergen
WO2003031981A2 (en) * 2001-10-05 2003-04-17 Novozymes A/S Kit for predicting binding of a specific antibody to a potential immunogen and method of screening
PT1478662E (pt) * 2002-02-27 2009-12-29 Merck Patent Gmbh Método para o fabrico do alergeno principal do pólen de bétula hipoalergénico rbet v 1
EP1504089A2 (en) * 2002-05-16 2005-02-09 Alk Abell A/S Allergen mutants
JP2006520184A (ja) * 2002-11-01 2006-09-07 アルカベロ アクチェセルスカプ 組換えタンパク質変種
WO2004047793A1 (en) 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
US8012505B2 (en) 2003-02-28 2011-09-06 Alk-Abello A/S Dosage form having a saccharide matrix
CA2516291C (en) 2003-02-28 2012-02-14 Alk-Abello A/S Dosage form having a saccharide matrix
EP2272502A1 (en) 2003-12-19 2011-01-12 Alk-Abelló A/S Cryogranules of a liquid composition of an allergen product
EP2324850A1 (en) 2005-10-04 2011-05-25 Alk-Abelló A/S Solid vaccine formulation
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
JP2009534029A (ja) * 2006-04-20 2009-09-24 ナショナル ユニバーシティ オブ シンガポール 組換え乳酸桿菌およびその使用
CN101657213B (zh) * 2007-02-15 2014-02-26 曼康公司 用于增强t细胞应答的方法
EP1974746B1 (en) 2007-03-28 2012-01-11 Alk-Abelló A/S Use of an adjuvanted allergy vaccine formulation for parenteral administration
EP2028188A1 (en) * 2007-08-21 2009-02-25 Biomay AG Hypoallergenic molecules
DE202008006598U1 (de) 2008-04-11 2008-10-02 Alk-Abelló A/S Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
WO2010146171A1 (en) 2009-06-19 2010-12-23 Alk-Abelló A/S Novel manner of administering allergen in allergen specific immunotherapy
CN102584966A (zh) * 2011-11-14 2012-07-18 广州医学院第二附属医院 一种重组花生过敏原与突变体及其制备方法和应用
CN102690340A (zh) * 2012-03-30 2012-09-26 广州医学院第二附属医院 一种重组巴西坚果过敏原与突变体及其制备方法和应用
CN102617719A (zh) * 2012-03-30 2012-08-01 广州医学院第二附属医院 一种重组大米过敏原与突变体及其制备方法和应用
CN102603879A (zh) * 2012-03-30 2012-07-25 广州医学院第二附属医院 一种重组大豆过敏原与突变体及其制备方法和应用
CN102617715A (zh) * 2012-03-30 2012-08-01 广州医学院第二附属医院 一种重组真菌主要过敏原与突变体及其制备方法和应用
CN102675439A (zh) * 2012-03-31 2012-09-19 广州医学院第二附属医院 一种重组黑麦草花粉过敏原与突变体的制备方法和应用
EP2952200A1 (en) 2014-06-04 2015-12-09 Alk-Abelló A/S Allergen for prophylactic treatment of allergy
EP4058059B1 (en) * 2019-11-13 2024-10-09 The Regents Of The University Of Michigan Nanoemulsion compositions for treating aeroallergen associated allergy and inflammation
CN111187606B (zh) * 2020-02-25 2022-06-14 江苏海洋大学 一种用于海水基可循环清洁压裂液的表面活性剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804201A (en) * 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5
CA2319437C (en) * 1998-01-31 2009-06-16 University Of Arkansas Methods and reagents for decreasing allergic reactions
IT1318692B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti di proteine allergeniche di phleum pratense.

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLINICAL & EXPERIMENTAL ALLERGY, 27, PP 593-599 (1997) *
FASEB J FOR EXPERIMENTAL BIOLOGY, 12, PP 231-242 (1998) *
J BIOL. CHEM., 271, PP 29915-29921 (1996) *

Also Published As

Publication number Publication date
ES2313776T3 (es) 2009-03-01
CA2323687C (en) 2008-11-25
NO20004614D0 (no) 2000-09-15
ZA200004819B (en) 2001-05-30
HUP0101464A3 (en) 2004-10-28
NO20004614L (no) 2000-10-26
IL138339A0 (en) 2001-10-31
WO1999047680A1 (en) 1999-09-23
US20040091500A1 (en) 2004-05-13
CN1332029C (zh) 2007-08-15
AU2714799A (en) 1999-10-11
DK1062341T3 (da) 2008-11-03
EP1062341B1 (en) 2008-09-17
PT1062341E (pt) 2008-12-24
NO328354B1 (no) 2010-02-01
JP2002506648A (ja) 2002-03-05
PL343029A1 (en) 2001-07-30
KR20010041918A (ko) 2001-05-25
HK1033591A1 (en) 2001-09-07
HUP0101464A2 (hu) 2001-08-28
CN1293710A (zh) 2001-05-02
IL138339A (en) 2009-06-15
ATE408690T1 (de) 2008-10-15
DE69939584D1 (de) 2008-10-30
CA2323687A1 (en) 1999-09-23
EP1062341A1 (en) 2000-12-27
NZ506665A (en) 2003-08-29
PL194804B1 (pl) 2007-07-31

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