AU749749B2 - Mutant recombinant allergens - Google Patents

Mutant recombinant allergens Download PDF

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Publication number
AU749749B2
AU749749B2 AU27147/99A AU2714799A AU749749B2 AU 749749 B2 AU749749 B2 AU 749749B2 AU 27147/99 A AU27147/99 A AU 27147/99A AU 2714799 A AU2714799 A AU 2714799A AU 749749 B2 AU749749 B2 AU 749749B2
Authority
AU
Australia
Prior art keywords
allergen
recombinant
derived
amino acid
recombinant allergen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27147/99A
Other languages
English (en)
Other versions
AU2714799A (en
Inventor
Hans Henrik Ipsen
Jorgen Nedergaard Larsen
Michael Dho Spangfort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALK Abello AS
Original Assignee
ALK Abello AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8092687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU749749(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ALK Abello AS filed Critical ALK Abello AS
Publication of AU2714799A publication Critical patent/AU2714799A/en
Application granted granted Critical
Publication of AU749749B2 publication Critical patent/AU749749B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU27147/99A 1998-03-16 1999-03-16 Mutant recombinant allergens Ceased AU749749B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK36498 1998-03-16
DK364/98 1998-03-16
PCT/DK1999/000136 WO1999047680A1 (en) 1998-03-16 1999-03-16 Mutant recombinant allergens

Publications (2)

Publication Number Publication Date
AU2714799A AU2714799A (en) 1999-10-11
AU749749B2 true AU749749B2 (en) 2002-07-04

Family

ID=8092687

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27147/99A Ceased AU749749B2 (en) 1998-03-16 1999-03-16 Mutant recombinant allergens

Country Status (19)

Country Link
US (1) US20040091500A1 (enExample)
EP (1) EP1062341B1 (enExample)
JP (1) JP2002506648A (enExample)
KR (1) KR20010041918A (enExample)
CN (1) CN1332029C (enExample)
AT (1) ATE408690T1 (enExample)
AU (1) AU749749B2 (enExample)
CA (1) CA2323687C (enExample)
DE (1) DE69939584D1 (enExample)
DK (1) DK1062341T3 (enExample)
ES (1) ES2313776T3 (enExample)
HU (1) HUP0101464A3 (enExample)
IL (2) IL138339A0 (enExample)
NO (1) NO328354B1 (enExample)
NZ (1) NZ506665A (enExample)
PL (1) PL194804B1 (enExample)
PT (1) PT1062341E (enExample)
WO (1) WO1999047680A1 (enExample)
ZA (1) ZA200004819B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020192792A1 (en) * 2000-04-28 2002-12-19 Palle Schneider Laccase mutants
IT1318692B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti di proteine allergeniche di phleum pratense.
IT1318690B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti dell'allergene maggiore par j 2 di parietaria judaica.
EP1340085B1 (en) * 2000-10-17 2008-07-30 Besst-Test Aps Assay for directly detecting a biological cell in a body fluid sample
DE60136653D1 (de) * 2000-11-16 2009-01-02 Alk Abello As Mutante allergene
DK1219300T3 (da) * 2000-12-28 2007-03-05 Biomay Prod & Handel Behandling af allergi
ATE448793T1 (de) * 2001-03-02 2009-12-15 Univ Rockefeller Rekombinante hybrid-allergenkonstrukte mit verringerter allergenität unter beibehaltung der immunogenität des natürlichen allergens
EP1436627A2 (en) * 2001-10-05 2004-07-14 Novozymes A/S Kit for predicting binding of a specific antibody to a potential immunogen and method of screening
WO2003072601A1 (de) * 2002-02-27 2003-09-04 Merck Patent Gmbh VERFAHREN ZUR HERSTELLUNG VON HYPOALLERGENEM BIRKENPOLLENHAUPTALLERGEN rBet v 1
EP1504089A2 (en) * 2002-05-16 2005-02-09 Alk Abell A/S Allergen mutants
WO2004039834A2 (en) * 2002-11-01 2004-05-13 Alk-Abelló A/S Recombinant protein variants
WO2004047793A1 (en) 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
US8012505B2 (en) 2003-02-28 2011-09-06 Alk-Abello A/S Dosage form having a saccharide matrix
CA2516291C (en) 2003-02-28 2012-02-14 Alk-Abello A/S Dosage form having a saccharide matrix
WO2005058474A1 (en) 2003-12-19 2005-06-30 Alk-Abelló A/S Cryogranulation and storage method for active pharmaceutical agents
AU2006299310A1 (en) 2005-10-04 2007-04-12 Alk-Abello A/S Solid vaccine formulation
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
CN101473028B (zh) * 2006-04-20 2012-11-07 新加坡国立大学 重组乳杆菌及其用途
EP2481418A1 (en) * 2007-02-15 2012-08-01 MannKind Corporation A method for enhancing T cell response
EP1974746B1 (en) 2007-03-28 2012-01-11 Alk-Abelló A/S Use of an adjuvanted allergy vaccine formulation for parenteral administration
EP2028188A1 (en) * 2007-08-21 2009-02-25 Biomay AG Hypoallergenic molecules
DE202008006598U1 (de) 2008-04-11 2008-10-02 Alk-Abelló A/S Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
EP2442828B1 (en) 2009-06-19 2016-08-03 Alk-Abelló S.A. Novel manner of administrating allergen in allergen specific immunotherapy
CN102584966A (zh) * 2011-11-14 2012-07-18 广州医学院第二附属医院 一种重组花生过敏原与突变体及其制备方法和应用
CN102690340A (zh) * 2012-03-30 2012-09-26 广州医学院第二附属医院 一种重组巴西坚果过敏原与突变体及其制备方法和应用
CN102603879A (zh) * 2012-03-30 2012-07-25 广州医学院第二附属医院 一种重组大豆过敏原与突变体及其制备方法和应用
CN102617715A (zh) * 2012-03-30 2012-08-01 广州医学院第二附属医院 一种重组真菌主要过敏原与突变体及其制备方法和应用
CN102617719A (zh) * 2012-03-30 2012-08-01 广州医学院第二附属医院 一种重组大米过敏原与突变体及其制备方法和应用
CN102675439A (zh) * 2012-03-31 2012-09-19 广州医学院第二附属医院 一种重组黑麦草花粉过敏原与突变体的制备方法和应用
EP2952200A1 (en) 2014-06-04 2015-12-09 Alk-Abelló A/S Allergen for prophylactic treatment of allergy
EP4058059B1 (en) * 2019-11-13 2024-10-09 The Regents Of The University Of Michigan Nanoemulsion compositions for treating aeroallergen associated allergy and inflammation
CN111187606B (zh) * 2020-02-25 2022-06-14 江苏海洋大学 一种用于海水基可循环清洁压裂液的表面活性剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804201A (en) * 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5
DE69940805D1 (de) * 1998-01-31 2009-06-10 Sinai School Medicine Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie
IT1318692B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti di proteine allergeniche di phleum pratense.

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLINICAL & EXPERIMENTAL ALLERGY, 27, PP 593-599 (1997) *
FASEB J FOR EXPERIMENTAL BIOLOGY, 12, PP 231-242 (1998) *
J BIOL. CHEM., 271, PP 29915-29921 (1996) *

Also Published As

Publication number Publication date
NO328354B1 (no) 2010-02-01
NO20004614D0 (no) 2000-09-15
CA2323687C (en) 2008-11-25
NO20004614L (no) 2000-10-26
EP1062341B1 (en) 2008-09-17
WO1999047680A1 (en) 1999-09-23
ES2313776T3 (es) 2009-03-01
HUP0101464A3 (en) 2004-10-28
CN1332029C (zh) 2007-08-15
ATE408690T1 (de) 2008-10-15
DK1062341T3 (da) 2008-11-03
ZA200004819B (en) 2001-05-30
PL343029A1 (en) 2001-07-30
CA2323687A1 (en) 1999-09-23
AU2714799A (en) 1999-10-11
HUP0101464A2 (hu) 2001-08-28
NZ506665A (en) 2003-08-29
CN1293710A (zh) 2001-05-02
HK1033591A1 (en) 2001-09-07
EP1062341A1 (en) 2000-12-27
IL138339A0 (en) 2001-10-31
JP2002506648A (ja) 2002-03-05
PL194804B1 (pl) 2007-07-31
DE69939584D1 (de) 2008-10-30
KR20010041918A (ko) 2001-05-25
PT1062341E (pt) 2008-12-24
IL138339A (en) 2009-06-15
US20040091500A1 (en) 2004-05-13

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