AU748730B2 - An attenuated Japanese encephalitis virus adapted to vero cell and a Japanese encephalitis vaccine - Google Patents

An attenuated Japanese encephalitis virus adapted to vero cell and a Japanese encephalitis vaccine Download PDF

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Publication number
AU748730B2
AU748730B2 AU90047/98A AU9004798A AU748730B2 AU 748730 B2 AU748730 B2 AU 748730B2 AU 90047/98 A AU90047/98 A AU 90047/98A AU 9004798 A AU9004798 A AU 9004798A AU 748730 B2 AU748730 B2 AU 748730B2
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AU
Australia
Prior art keywords
virus
japanese encephalitis
vaccine
attenuated
vero cell
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Expired, expires
Application number
AU90047/98A
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English (en)
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AU9004798A (en
Inventor
Leonard N. Binn
Yong Ju Chung
Doria R. Dubois
Kenneth H. Eckels
Sun Pyo Hong
Bruce Innis
Hyun Su Kim
Soo Ok Kim
Sung Hee Lee
Sang Bum Moon
Joseph R. Putnak
Yong Cheol Shin
Ashok K. Srivastava
Wang Don Yoo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ Corp
Walter Reed Army Institute of Research
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CJ Corp
US Department of Army
Walter Reed Army Institute of Research
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Publication of AU9004798A publication Critical patent/AU9004798A/en
Application granted granted Critical
Publication of AU748730B2 publication Critical patent/AU748730B2/en
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24151Methods of production or purification of viral material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU90047/98A 1997-08-28 1998-08-25 An attenuated Japanese encephalitis virus adapted to vero cell and a Japanese encephalitis vaccine Expired AU748730B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR19970042002 1997-08-28
KR1997/42001 1997-08-28
KR19970042001 1997-08-28
KR1997/42002 1997-08-28
PCT/KR1998/000259 WO1999011762A1 (en) 1997-08-28 1998-08-25 An attenuated japanese encephalitis virus adapted to vero cell and a japanese encephalitis vaccine

Publications (2)

Publication Number Publication Date
AU9004798A AU9004798A (en) 1999-03-22
AU748730B2 true AU748730B2 (en) 2002-06-13

Family

ID=26633032

Family Applications (1)

Application Number Title Priority Date Filing Date
AU90047/98A Expired AU748730B2 (en) 1997-08-28 1998-08-25 An attenuated Japanese encephalitis virus adapted to vero cell and a Japanese encephalitis vaccine

Country Status (15)

Country Link
US (1) US6309650B1 (US06559137-20030506-C00039.png)
EP (2) EP1025209B1 (US06559137-20030506-C00039.png)
JP (1) JP4161017B2 (US06559137-20030506-C00039.png)
KR (1) KR100314404B1 (US06559137-20030506-C00039.png)
CN (1) CN1142271C (US06559137-20030506-C00039.png)
AU (1) AU748730B2 (US06559137-20030506-C00039.png)
CA (1) CA2301000C (US06559137-20030506-C00039.png)
DE (2) DE69837211T2 (US06559137-20030506-C00039.png)
DK (2) DK1604685T3 (US06559137-20030506-C00039.png)
ES (2) ES2382946T3 (US06559137-20030506-C00039.png)
FR (1) FR09C0037I2 (US06559137-20030506-C00039.png)
MY (1) MY129773A (US06559137-20030506-C00039.png)
NL (1) NL300391I2 (US06559137-20030506-C00039.png)
NZ (1) NZ503522A (US06559137-20030506-C00039.png)
WO (1) WO1999011762A1 (US06559137-20030506-C00039.png)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000083657A (ja) * 1998-07-13 2000-03-28 Chemo Sero Therapeut Res Inst 日本脳炎ウイルスワクチン
JP4371343B2 (ja) 1998-10-05 2009-11-25 財団法人阪大微生物病研究会 日本脳炎ウイルス群感染症に対する不活化ワクチンのための増強免疫原およびその製造方法
JP4778620B2 (ja) * 1999-04-22 2011-09-21 ユナイテッド ステイツ デパートメント オブ アグリカルチャー 分離株ja−142に基づく、豚繁殖・呼吸障害症候群ワクチン
AU4472801A (en) * 2000-04-07 2001-10-23 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Inactivated japanese B encephalitis vaccine and process for producing the same
CN1253220C (zh) * 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
JP2007068401A (ja) * 2003-08-07 2007-03-22 Chemo Sero Therapeut Res Inst 西ナイルウイルスワクチン
NZ548495A (en) * 2004-02-23 2009-05-31 Crucell Holland Bv Virus purification methods
CN100340596C (zh) * 2004-05-20 2007-10-03 佛山市顺德区汉达精密电子科技有限公司 回收聚碳酸酯/丙烯腈-丁二烯-苯乙烯共聚物及其回收方法
DK1869171T4 (en) * 2005-04-11 2016-01-18 Crucell Holland Bv Virus cleaning using ultrafiltration
US8591916B2 (en) * 2007-01-31 2013-11-26 Sanofi Pasteur Biologics, Llc Flavivirus vaccine vector against influenza virus
CA2710611C (en) * 2007-12-26 2016-12-20 The Kitasato Institute Method of producing japanese encephalitis vaccine stably storable over long time and use of the vaccine
JP5511660B2 (ja) * 2008-06-04 2014-06-04 一般財団法人化学及血清療法研究所 不活化日本脳炎ウイルス粒子をアジュバントとして使用する方法
JP5744517B2 (ja) * 2008-07-30 2015-07-08 久光製薬株式会社 マイクロニードルデバイスおよびマイクロニードルデバイスによる日本脳炎ウイルス抗原の奏功性を上昇させる方法
KR20120027381A (ko) * 2009-05-25 2012-03-21 파나세아 바이오테크 리미티드 일본뇌염 백신 및 그것의 제조 방법
KR101144993B1 (ko) * 2009-06-18 2012-06-27 대한민국 돼지 일본뇌염 바이러스의 고농축 혈구응집용 항원
SI3106176T1 (en) 2011-12-06 2018-04-30 Valneva Austria Gmbh Aluminum compounds for use in therapeutics and vaccines
AU2014338520B2 (en) * 2013-09-14 2019-12-05 Bharat Biotech International Limited A viral vaccine and methods of manufacture thereof
CN105695424B (zh) * 2015-04-01 2019-06-14 中国食品药品检定研究院 乙型脑炎减毒活疫苗株sa14-14-2在人二倍体细胞2bs上的适应株及其疫苗
FI3393510T3 (fi) 2015-12-23 2023-03-22 Valneva Austria Gmbh Zika-virusrokote
AU2017207076B2 (en) * 2016-01-15 2021-04-29 Km Biologics Co., Ltd. Vaccine containing immobilized virus particles
US11033615B2 (en) 2016-05-31 2021-06-15 The Government of the United States, As Represented by the Secretary of the Army Fort Detrick, Maryland Zika virus vaccine and methods of production
WO2019057793A1 (en) 2017-09-21 2019-03-28 Valneva Se PROCESS FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS COMPRISING THE IMMUNOGENIC VIRUS OF CHIKUNGUNYA CHIKV-DELTA5NSP3
WO2019090228A2 (en) 2017-11-03 2019-05-09 Takeda Vaccines, Inc. Zika vaccines and immunogenic compositions, and methods of using the same
CN111601885A (zh) 2017-11-30 2020-08-28 武田疫苗股份有限公司 用于将寨卡病毒灭活的方法和相关方法
CN110684747B (zh) * 2018-07-06 2024-05-24 厦门大学 灭活及保存呼吸道合胞病毒的方法
CN112601815A (zh) * 2018-08-27 2021-04-02 迈凯恩技术有限公司 使用永生化单核细胞和诱导细胞的抗感染药物、疫苗等的评价方法
EP3895729A1 (en) 2020-03-01 2021-10-20 Valneva Austria GmbH Cpg-adjuvanted sars-cov-2 virus vaccine
JP2023515908A (ja) 2020-03-01 2023-04-14 ヴァルネヴァ・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング CpGアジュバント化SARS-CoV-2ウイルスワクチン
TW202203967A (zh) 2020-04-06 2022-02-01 奧地利商瓦爾尼瓦奧地利有限責任公司 不活化SARS—CoV—2病毒疫苗
WO2023148256A1 (en) 2022-02-02 2023-08-10 Valneva Austria Gmbh Inactivated sars-cov-2 virus vaccine

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JP2704258B2 (ja) * 1987-10-31 1998-01-26 日本臓器製薬株式会社 組み換えワクチニアウイルス
GB8821656D0 (en) * 1988-09-15 1988-10-12 Health Lab Service Board Pharmaceutical compositions for eliciting immunostimulant effect
JPH085803B2 (ja) * 1988-11-10 1996-01-24 武田薬品工業株式会社 日本脳炎ワクチンの製造法
EP0562136A1 (en) * 1992-03-24 1993-09-29 Division Of Microbiology, Kyoto Biken Laboratories, Inc. Live vaccine to getah virus infectious disease, and trivalent live vaccine to Japanese encephalitis virus, porcine parvovirus and getah virus infectious diseases
US6010894A (en) * 1997-06-13 2000-01-04 Research Development Foundation Method of screening for attenuating viruses

Also Published As

Publication number Publication date
EP1604685A3 (en) 2006-07-05
NL300391I1 (nl) 2009-08-03
EP1025209B1 (en) 2007-02-28
DK1025209T3 (da) 2007-06-25
JP4161017B2 (ja) 2008-10-08
NZ503522A (en) 2001-06-29
DE122009000037I2 (de) 2011-06-16
CN1272879A (zh) 2000-11-08
DE69837211D1 (de) 2007-04-12
CA2301000C (en) 2003-07-08
ES2382946T3 (es) 2012-06-14
CA2301000A1 (en) 1999-03-11
KR100314404B1 (ko) 2002-10-12
DE122009000037I1 (de) 2009-11-05
FR09C0037I2 (fr) 2021-11-05
ES2281929T3 (es) 2007-10-01
AU9004798A (en) 1999-03-22
US6309650B1 (en) 2001-10-30
EP1604685B1 (en) 2012-02-22
MY129773A (en) 2007-04-30
DK1604685T3 (da) 2012-06-18
EP1025209A1 (en) 2000-08-09
EP1604685A2 (en) 2005-12-14
NL300391I2 (nl) 2009-11-02
WO1999011762A1 (en) 1999-03-11
KR19990023955A (ko) 1999-03-25
JP2001514844A (ja) 2001-09-18
CN1142271C (zh) 2004-03-17
FR09C0037I1 (US06559137-20030506-C00039.png) 2009-09-25
DE69837211T2 (de) 2007-12-06

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