AU739140B2 - Mycobacterial inhibitors - Google Patents

Mycobacterial inhibitors Download PDF

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Publication number
AU739140B2
AU739140B2 AU43041/99A AU4304199A AU739140B2 AU 739140 B2 AU739140 B2 AU 739140B2 AU 43041/99 A AU43041/99 A AU 43041/99A AU 4304199 A AU4304199 A AU 4304199A AU 739140 B2 AU739140 B2 AU 739140B2
Authority
AU
Australia
Prior art keywords
group
dione
nonyl
ethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU43041/99A
Other languages
English (en)
Other versions
AU4304199A (en
Inventor
Meenakshi Balganesh
Kantharaj Ethirajulu
Babita Singh Ganguly
Ramachandran Janakiraman
Rangarao Kajipalya
Parvinder Kaur
Ramanujulu Pondi Murugappan
Santosh Nandan
Narayanan Ramamurthy
Balasubramanian Venkataraman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9802118A external-priority patent/SE9802118D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU4304199A publication Critical patent/AU4304199A/en
Application granted granted Critical
Publication of AU739140B2 publication Critical patent/AU739140B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU43041/99A 1998-05-05 1999-05-03 Mycobacterial inhibitors Ceased AU739140B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN969/MAS/98 1998-05-05
IN969MA1998 1998-05-05
SE9802118A SE9802118D0 (sv) 1998-06-15 1998-06-15 Mycobacterial inhibitors
SE9802118 1998-06-15
PCT/SE1999/000732 WO1999065483A1 (en) 1998-05-05 1999-05-03 Mycobacterial inhibitors

Publications (2)

Publication Number Publication Date
AU4304199A AU4304199A (en) 2000-01-05
AU739140B2 true AU739140B2 (en) 2001-10-04

Family

ID=26324850

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43041/99A Ceased AU739140B2 (en) 1998-05-05 1999-05-03 Mycobacterial inhibitors

Country Status (14)

Country Link
US (1) US6476053B1 (https=)
EP (1) EP1075261B1 (https=)
JP (1) JP2002518324A (https=)
KR (1) KR20010043322A (https=)
CN (1) CN1201735C (https=)
AT (1) ATE322898T1 (https=)
AU (1) AU739140B2 (https=)
BR (1) BR9910185A (https=)
CA (1) CA2330667A1 (https=)
DE (1) DE69930844T2 (https=)
IL (1) IL139144A0 (https=)
NO (1) NO20005548L (https=)
NZ (1) NZ507620A (https=)
WO (1) WO1999065483A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002350115A1 (en) 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
KR20080034944A (ko) * 2005-08-19 2008-04-22 아스트라제네카 아베 결핵 치료용 피라졸론 유도체
GB0520368D0 (en) * 2005-10-06 2005-11-16 Univ Aston Antibacterial pyrrols
EP2373617B1 (de) 2008-12-04 2015-02-25 Basf Se Mischungen aus itaconsäure oder itaconsäurederivaten und primären aminen zur herstellung von 1,3- und 1,4-alkylmethylpyrrolidonen
CA3009323C (en) * 2015-12-23 2023-01-24 Henkel Ag & Co. Kgaa Metal working fluid
CN107033060B (zh) * 2017-05-04 2020-01-14 浙江工业大学 一种n-取代顺丁烯二酰亚胺类化合物及其制备与抗菌应用
CN111465611B (zh) * 2017-12-01 2024-10-11 古德T细胞有限公司 预防或治疗脱发的组合物
CN119569636B (zh) * 2024-10-22 2026-03-27 南京吉星生物技术开发有限公司 一种吡咯啉二酮类化合物及其制备方法和杀菌剂应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883342A (en) * 1973-04-13 1975-05-13 Akzona Inc Plant growth regulators

Also Published As

Publication number Publication date
NO20005548L (no) 2000-12-04
EP1075261A1 (en) 2001-02-14
CN1201735C (zh) 2005-05-18
JP2002518324A (ja) 2002-06-25
NO20005548D0 (no) 2000-11-03
DE69930844D1 (de) 2006-05-24
DE69930844T2 (de) 2006-12-28
CA2330667A1 (en) 1999-12-23
ATE322898T1 (de) 2006-04-15
BR9910185A (pt) 2001-01-09
EP1075261B1 (en) 2006-04-12
US6476053B1 (en) 2002-11-05
IL139144A0 (en) 2001-11-25
WO1999065483A1 (en) 1999-12-23
KR20010043322A (ko) 2001-05-25
NZ507620A (en) 2003-05-30
CN1308532A (zh) 2001-08-15
AU4304199A (en) 2000-01-05

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