AU730245B2 - Sulfate salt of an HIV protease inhibitor having an improved oral absorption and bioavailability - Google Patents
Sulfate salt of an HIV protease inhibitor having an improved oral absorption and bioavailability Download PDFInfo
- Publication number
- AU730245B2 AU730245B2 AU75959/98A AU7595998A AU730245B2 AU 730245 B2 AU730245 B2 AU 730245B2 AU 75959/98 A AU75959/98 A AU 75959/98A AU 7595998 A AU7595998 A AU 7595998A AU 730245 B2 AU730245 B2 AU 730245B2
- Authority
- AU
- Australia
- Prior art keywords
- compound
- treating
- composition
- crystalline compound
- crystalline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4795097P | 1997-05-29 | 1997-05-29 | |
| US60/047950 | 1997-05-29 | ||
| GB9714320 | 1997-07-07 | ||
| GBGB9714320.0A GB9714320D0 (en) | 1997-07-07 | 1997-07-07 | Hiv protease inhibitor |
| PCT/US1998/010633 WO1998054178A1 (en) | 1997-05-29 | 1998-05-26 | Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7595998A AU7595998A (en) | 1998-12-30 |
| AU730245B2 true AU730245B2 (en) | 2001-03-01 |
Family
ID=26311845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU75959/98A Ceased AU730245B2 (en) | 1997-05-29 | 1998-05-26 | Sulfate salt of an HIV protease inhibitor having an improved oral absorption and bioavailability |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0986554A1 (pt) |
| JP (1) | JP3267632B2 (pt) |
| KR (1) | KR20010013042A (pt) |
| CN (1) | CN1257497A (pt) |
| AU (1) | AU730245B2 (pt) |
| BG (1) | BG103923A (pt) |
| BR (1) | BR9809498A (pt) |
| CA (1) | CA2291086A1 (pt) |
| EA (1) | EA199901095A1 (pt) |
| EE (1) | EE9900543A (pt) |
| HR (1) | HRP980283A2 (pt) |
| HU (1) | HUP0004621A3 (pt) |
| ID (1) | ID23858A (pt) |
| IL (1) | IL132779A0 (pt) |
| IS (1) | IS5240A (pt) |
| NO (1) | NO995822L (pt) |
| PE (1) | PE75099A1 (pt) |
| PL (1) | PL336847A1 (pt) |
| SK (1) | SK163299A3 (pt) |
| TR (1) | TR199902816T2 (pt) |
| TW (1) | TW438799B (pt) |
| WO (1) | WO1998054178A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003514910A (ja) * | 1999-11-24 | 2003-04-22 | メルク エンド カムパニー インコーポレーテッド | Ｈｉｖプロテアーゼ阻害剤としてのガンマ−ヒドロキシ−２−（フルオロアルキルアミノカルボニル）−１−ピペラジンペンタンアミド類 |
| WO2002022582A2 (en) * | 2000-09-14 | 2002-03-21 | Ortho-Mcneil Pharmaceutical, Inc. | Solid salt forms of n-[2-[4-[2-(1-methylethoxy)phenyl]-1-piperazinyl]ethyl]-2-oxo-1-piperidineacetamide |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995016688A1 (en) * | 1993-12-15 | 1995-06-22 | Merck & Co., Inc. | Hiv protease inhibitors |
-
1998
- 1998-05-20 TW TW087107834A patent/TW438799B/zh active
- 1998-05-26 TR TR1999/02816T patent/TR199902816T2/xx unknown
- 1998-05-26 ID IDW991462A patent/ID23858A/id unknown
- 1998-05-26 PL PL98336847A patent/PL336847A1/xx unknown
- 1998-05-26 EE EEP199900543A patent/EE9900543A/xx unknown
- 1998-05-26 EP EP98923741A patent/EP0986554A1/en not_active Withdrawn
- 1998-05-26 IL IL13277998A patent/IL132779A0/xx unknown
- 1998-05-26 BR BR9809498-0A patent/BR9809498A/pt not_active Application Discontinuation
- 1998-05-26 KR KR1019997011018A patent/KR20010013042A/ko not_active Application Discontinuation
- 1998-05-26 JP JP50079999A patent/JP3267632B2/ja not_active Expired - Fee Related
- 1998-05-26 WO PCT/US1998/010633 patent/WO1998054178A1/en not_active Application Discontinuation
- 1998-05-26 CN CN98805372A patent/CN1257497A/zh active Pending
- 1998-05-26 HU HU0004621A patent/HUP0004621A3/hu unknown
- 1998-05-26 CA CA002291086A patent/CA2291086A1/en not_active Abandoned
- 1998-05-26 SK SK1632-99A patent/SK163299A3/sk unknown
- 1998-05-26 EA EA199901095A patent/EA199901095A1/ru unknown
- 1998-05-26 AU AU75959/98A patent/AU730245B2/en not_active Ceased
- 1998-05-28 PE PE1998000432A patent/PE75099A1/es not_active Application Discontinuation
- 1998-05-28 HR HR9714320.0A patent/HRP980283A2/hr not_active Application Discontinuation
-
1999
- 1999-11-09 IS IS5240A patent/IS5240A/is unknown
- 1999-11-24 BG BG103923A patent/BG103923A/xx unknown
- 1999-11-26 NO NO995822A patent/NO995822L/no not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995016688A1 (en) * | 1993-12-15 | 1995-06-22 | Merck & Co., Inc. | Hiv protease inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998054178A1 (en) | 1998-12-03 |
| KR20010013042A (ko) | 2001-02-26 |
| BG103923A (en) | 2000-06-30 |
| HRP980283A2 (en) | 1999-08-31 |
| IL132779A0 (en) | 2001-03-19 |
| NO995822D0 (no) | 1999-11-26 |
| HUP0004621A2 (hu) | 2002-03-28 |
| NO995822L (no) | 2000-01-28 |
| SK163299A3 (en) | 2000-07-11 |
| AU7595998A (en) | 1998-12-30 |
| EE9900543A (et) | 2000-06-15 |
| EA199901095A1 (ru) | 2000-08-28 |
| PL336847A1 (en) | 2000-07-17 |
| CN1257497A (zh) | 2000-06-21 |
| TW438799B (en) | 2001-06-07 |
| BR9809498A (pt) | 2000-06-20 |
| ID23858A (id) | 2000-05-25 |
| CA2291086A1 (en) | 1998-12-03 |
| TR199902816T2 (xx) | 2000-02-21 |
| PE75099A1 (es) | 1999-08-11 |
| EP0986554A1 (en) | 2000-03-22 |
| JP2000513747A (ja) | 2000-10-17 |
| HUP0004621A3 (en) | 2002-04-29 |
| IS5240A (is) | 1999-11-09 |
| JP3267632B2 (ja) | 2002-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |