IL132779A0 - Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailability - Google Patents
Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailabilityInfo
- Publication number
- IL132779A0 IL132779A0 IL13277998A IL13277998A IL132779A0 IL 132779 A0 IL132779 A0 IL 132779A0 IL 13277998 A IL13277998 A IL 13277998A IL 13277998 A IL13277998 A IL 13277998A IL 132779 A0 IL132779 A0 IL 132779A0
- Authority
- IL
- Israel
- Prior art keywords
- bioavailability
- protease inhibitor
- hiv protease
- sulfate salt
- oral absorption
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4795097P | 1997-05-29 | 1997-05-29 | |
| GBGB9714320.0A GB9714320D0 (en) | 1997-07-07 | 1997-07-07 | Hiv protease inhibitor |
| PCT/US1998/010633 WO1998054178A1 (en) | 1997-05-29 | 1998-05-26 | Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL132779A0 true IL132779A0 (en) | 2001-03-19 |
Family
ID=26311845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13277998A IL132779A0 (en) | 1997-05-29 | 1998-05-26 | Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailability |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0986554A1 (pt) |
| JP (1) | JP3267632B2 (pt) |
| KR (1) | KR20010013042A (pt) |
| CN (1) | CN1257497A (pt) |
| AU (1) | AU730245B2 (pt) |
| BG (1) | BG103923A (pt) |
| BR (1) | BR9809498A (pt) |
| CA (1) | CA2291086A1 (pt) |
| EA (1) | EA199901095A1 (pt) |
| EE (1) | EE9900543A (pt) |
| HR (1) | HRP980283A2 (pt) |
| HU (1) | HUP0004621A3 (pt) |
| ID (1) | ID23858A (pt) |
| IL (1) | IL132779A0 (pt) |
| IS (1) | IS5240A (pt) |
| NO (1) | NO995822L (pt) |
| PE (1) | PE75099A1 (pt) |
| PL (1) | PL336847A1 (pt) |
| SK (1) | SK163299A3 (pt) |
| TR (1) | TR199902816T2 (pt) |
| TW (1) | TW438799B (pt) |
| WO (1) | WO1998054178A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003514910A (ja) * | 1999-11-24 | 2003-04-22 | メルク エンド カムパニー インコーポレーテッド | Ｈｉｖプロテアーゼ阻害剤としてのガンマ−ヒドロキシ−２−（フルオロアルキルアミノカルボニル）−１−ピペラジンペンタンアミド類 |
| WO2002022582A2 (en) * | 2000-09-14 | 2002-03-21 | Ortho-Mcneil Pharmaceutical, Inc. | Solid salt forms of n-[2-[4-[2-(1-methylethoxy)phenyl]-1-piperazinyl]ethyl]-2-oxo-1-piperidineacetamide |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ278201A (en) * | 1993-12-15 | 1998-01-26 | Merck & Co Inc | Bicyclic heterocyclically substituted piperazine derivatives as hiv protease inhibitors |
-
1998
- 1998-05-20 TW TW087107834A patent/TW438799B/zh active
- 1998-05-26 TR TR1999/02816T patent/TR199902816T2/xx unknown
- 1998-05-26 ID IDW991462A patent/ID23858A/id unknown
- 1998-05-26 PL PL98336847A patent/PL336847A1/xx unknown
- 1998-05-26 EE EEP199900543A patent/EE9900543A/xx unknown
- 1998-05-26 EP EP98923741A patent/EP0986554A1/en not_active Withdrawn
- 1998-05-26 IL IL13277998A patent/IL132779A0/xx unknown
- 1998-05-26 BR BR9809498-0A patent/BR9809498A/pt not_active Application Discontinuation
- 1998-05-26 KR KR1019997011018A patent/KR20010013042A/ko not_active Application Discontinuation
- 1998-05-26 JP JP50079999A patent/JP3267632B2/ja not_active Expired - Fee Related
- 1998-05-26 WO PCT/US1998/010633 patent/WO1998054178A1/en not_active Application Discontinuation
- 1998-05-26 CN CN98805372A patent/CN1257497A/zh active Pending
- 1998-05-26 HU HU0004621A patent/HUP0004621A3/hu unknown
- 1998-05-26 CA CA002291086A patent/CA2291086A1/en not_active Abandoned
- 1998-05-26 SK SK1632-99A patent/SK163299A3/sk unknown
- 1998-05-26 EA EA199901095A patent/EA199901095A1/ru unknown
- 1998-05-26 AU AU75959/98A patent/AU730245B2/en not_active Ceased
- 1998-05-28 PE PE1998000432A patent/PE75099A1/es not_active Application Discontinuation
- 1998-05-28 HR HR9714320.0A patent/HRP980283A2/hr not_active Application Discontinuation
-
1999
- 1999-11-09 IS IS5240A patent/IS5240A/is unknown
- 1999-11-24 BG BG103923A patent/BG103923A/xx unknown
- 1999-11-26 NO NO995822A patent/NO995822L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998054178A1 (en) | 1998-12-03 |
| KR20010013042A (ko) | 2001-02-26 |
| BG103923A (en) | 2000-06-30 |
| HRP980283A2 (en) | 1999-08-31 |
| NO995822D0 (no) | 1999-11-26 |
| HUP0004621A2 (hu) | 2002-03-28 |
| NO995822L (no) | 2000-01-28 |
| SK163299A3 (en) | 2000-07-11 |
| AU7595998A (en) | 1998-12-30 |
| EE9900543A (et) | 2000-06-15 |
| EA199901095A1 (ru) | 2000-08-28 |
| PL336847A1 (en) | 2000-07-17 |
| CN1257497A (zh) | 2000-06-21 |
| TW438799B (en) | 2001-06-07 |
| BR9809498A (pt) | 2000-06-20 |
| ID23858A (id) | 2000-05-25 |
| CA2291086A1 (en) | 1998-12-03 |
| TR199902816T2 (xx) | 2000-02-21 |
| PE75099A1 (es) | 1999-08-11 |
| EP0986554A1 (en) | 2000-03-22 |
| JP2000513747A (ja) | 2000-10-17 |
| HUP0004621A3 (en) | 2002-04-29 |
| IS5240A (is) | 1999-11-09 |
| JP3267632B2 (ja) | 2002-03-18 |
| AU730245B2 (en) | 2001-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL300952I2 (nl) | Peramivir en farmaceutisch aanvaardbare zouten daarvan | |
| HK1033458A1 (en) | Bisulfate salt of hiv protease inhibitor | |
| PL338633A1 (en) | Derivatives of aryloxyarylsuphonylamino hydroxamic acid | |
| EP1039890A4 (en) | METFORMIN SALTS AND METHOD | |
| PL339551A1 (en) | Derivatives of rezorcin | |
| PL313871A1 (en) | Inhibitors of hiv protease | |
| PL339660A1 (en) | Derivatives of amidocarboxylic acids | |
| PL334846A1 (en) | Sulphamidic inhibitors of metaloproteases | |
| GB9805561D0 (en) | A combination of therapeutic agents | |
| PL338144A1 (en) | Derivatives of dolastatin 15 | |
| PL337725A1 (en) | Inhibitors of proteases | |
| PL340461A1 (en) | Derivatives of isothiazocarboxylic acid | |
| AU8638298A (en) | A piece of jewellery | |
| PL334769A1 (en) | Derivatives of 5-aroylnaphtene | |
| IL132779A0 (en) | Sulfate salt of an hiv protease inhibitor having an improved oral absorption and bioavailability | |
| GB9805557D0 (en) | A combination of therapeutic agents | |
| IL140766A0 (en) | Novel salts of n-tert-butylhydroxylamine | |
| AU1867899A (en) | Piece of jewellery | |
| ZA984514B (en) | Hiv protease inhibitor | |
| PL335675A1 (en) | Anticonvulsive derivatives of isoquinolinbenzamide | |
| ZA985064B (en) | Derivatives of pentaerythrits | |
| IL130670A0 (en) | Manufacture of elongate members | |
| EP1041986A4 (en) | PHARMACEUTICAL ACTIVE COMPOUND AND METHODS OF USE | |
| GB9813105D0 (en) | A piece of jewellery | |
| LT97098A (en) | Potassium salts of n-propionyl-4-hydroxy-3-nitro-l-phenylalanine and n-propionyl-4-metoxy-3-nitro-dl-phenylalanine having antitumour activity |