AU693622B2 - Amino acid nucleic acids - Google Patents

Amino acid nucleic acids Download PDF

Info

Publication number
AU693622B2
AU693622B2 AU42341/96A AU4234196A AU693622B2 AU 693622 B2 AU693622 B2 AU 693622B2 AU 42341/96 A AU42341/96 A AU 42341/96A AU 4234196 A AU4234196 A AU 4234196A AU 693622 B2 AU693622 B2 AU 693622B2
Authority
AU
Australia
Prior art keywords
lower alkyl
base
oligomers
oligonucleotide
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU42341/96A
Other languages
English (en)
Other versions
AU4234196A (en
Inventor
Kandasamy Ramasamy
Wilfried Seifert
Guangyi Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valeant Pharmaceuticals International Inc USA
Original Assignee
ICN Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICN Pharmaceuticals Inc filed Critical ICN Pharmaceuticals Inc
Publication of AU4234196A publication Critical patent/AU4234196A/en
Application granted granted Critical
Publication of AU693622B2 publication Critical patent/AU693622B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
AU42341/96A 1994-11-02 1995-11-02 Amino acid nucleic acids Ceased AU693622B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33389594A 1994-11-02 1994-11-02
US333895 1994-11-02
PCT/US1995/014599 WO1996014330A1 (en) 1994-11-02 1995-11-02 Amino acid nucleic acids

Publications (2)

Publication Number Publication Date
AU4234196A AU4234196A (en) 1996-05-31
AU693622B2 true AU693622B2 (en) 1998-07-02

Family

ID=23304698

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42341/96A Ceased AU693622B2 (en) 1994-11-02 1995-11-02 Amino acid nucleic acids

Country Status (13)

Country Link
EP (1) EP0789707A4 (ru)
JP (1) JPH10508312A (ru)
KR (1) KR100393336B1 (ru)
CN (1) CN1171112A (ru)
AU (1) AU693622B2 (ru)
CA (1) CA2202274A1 (ru)
HU (1) HU218086B (ru)
MX (1) MX9703188A (ru)
PL (1) PL185852B1 (ru)
RU (1) RU2154638C2 (ru)
SI (1) SI9520112A (ru)
UA (1) UA48150C2 (ru)
WO (1) WO1996014330A1 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840879A (en) * 1996-12-06 1998-11-24 Wang; Edge R. Reagents and solid supports for improved synthesis and labeling of polynucleotides
AU2002256168B2 (en) * 2001-04-10 2007-09-20 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic and diagnostic uses of antibody specificity profiles
CA2884340C (en) * 2007-11-15 2017-07-25 Sarepta Therapeutics, Inc. Method of synthesis of morpholino oligomers
WO2012074012A1 (ja) 2010-11-30 2012-06-07 独立行政法人科学技術振興機構 ヌクレオシド類縁体又はその塩、オリゴヌクレオチド類縁体、遺伝子発現抑制剤、及び遺伝子検出用核酸プローブ
RU2460721C1 (ru) * 2011-02-25 2012-09-10 Учреждение Российской академии наук Институт химической биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) Способ получения амидофосфитного мономера ахиральной ненуклеотидной вставки для модификации олигонуклеотидов
DE102014007158A1 (de) * 2014-05-16 2015-11-19 Ugichem Gmbh Neue Peptid-Nukleinsäuren-Monomere und -Oligomere
US11208429B2 (en) 2017-06-16 2021-12-28 Eisai R&D Management Co., Ltd. Modified nucleic acid monomer compound and oligonucleic acid analog
CN113956183B (zh) * 2021-10-28 2023-06-20 成都市科隆化学品有限公司 一种Boc-Ser(Bzl)-OH及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3650699T2 (de) * 1985-03-15 1999-04-15 Antivirals Inc Immunotestmittel für Polynukleotid und Verfahren
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf

Also Published As

Publication number Publication date
AU4234196A (en) 1996-05-31
RU2154638C2 (ru) 2000-08-20
WO1996014330A1 (en) 1996-05-17
KR970707144A (ko) 1997-12-01
JPH10508312A (ja) 1998-08-18
UA48150C2 (ru) 2002-08-15
PL185852B1 (pl) 2003-08-29
MX9703188A (es) 1997-12-31
EP0789707A1 (en) 1997-08-20
HU218086B (hu) 2000-05-28
KR100393336B1 (ko) 2003-12-24
SI9520112A (sl) 1998-08-31
HUT77435A (hu) 1998-04-28
CA2202274A1 (en) 1996-05-17
EP0789707A4 (en) 1999-02-24
CN1171112A (zh) 1998-01-21
PL320084A1 (en) 1997-09-15

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired