AU664115B2 - Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants - Google Patents

Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants Download PDF

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Publication number
AU664115B2
AU664115B2 AU48672/93A AU4867293A AU664115B2 AU 664115 B2 AU664115 B2 AU 664115B2 AU 48672/93 A AU48672/93 A AU 48672/93A AU 4867293 A AU4867293 A AU 4867293A AU 664115 B2 AU664115 B2 AU 664115B2
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AU
Australia
Prior art keywords
composition
modifier
ray
molecular weight
cloud point
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU48672/93A
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English (en)
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AU4867293A (en
Inventor
George C. Na
Natarajan Rajagopalan
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Nanosystems LLC
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Eastman Kodak Co
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Publication of AU4867293A publication Critical patent/AU4867293A/en
Assigned to EASTMAN KODAK COMPANY reassignment EASTMAN KODAK COMPANY Alteration of Name(s) of Applicant(s) under S113 Assignors: STERLING WINTHROP INC.
Application granted granted Critical
Publication of AU664115B2 publication Critical patent/AU664115B2/en
Assigned to NANOSYSTEMS L.L.C. reassignment NANOSYSTEMS L.L.C. Alteration of Name(s) in Register under S187 Assignors: EASTMAN KODAK COMPANY
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0476—Particles, beads, capsules, spheres
    • A61K49/0485—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A61K49/049—Surface-modified nanoparticles, e.g. immune-nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU48672/93A 1992-12-17 1993-09-29 Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants Ceased AU664115B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US991909 1992-12-17
US07/991,909 US5326552A (en) 1992-12-17 1992-12-17 Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants

Publications (2)

Publication Number Publication Date
AU4867293A AU4867293A (en) 1994-06-30
AU664115B2 true AU664115B2 (en) 1995-11-02

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ID=25537712

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48672/93A Ceased AU664115B2 (en) 1992-12-17 1993-09-29 Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants

Country Status (17)

Country Link
US (2) US5326552A (cg-RX-API-DMAC7.html)
EP (1) EP0602700A3 (cg-RX-API-DMAC7.html)
JP (1) JPH06192131A (cg-RX-API-DMAC7.html)
KR (1) KR940013544A (cg-RX-API-DMAC7.html)
AU (1) AU664115B2 (cg-RX-API-DMAC7.html)
CA (1) CA2107165A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ266893A3 (cg-RX-API-DMAC7.html)
FI (1) FI935396L (cg-RX-API-DMAC7.html)
HU (1) HUT67265A (cg-RX-API-DMAC7.html)
IL (1) IL107875A0 (cg-RX-API-DMAC7.html)
MX (1) MX9306012A (cg-RX-API-DMAC7.html)
MY (1) MY109875A (cg-RX-API-DMAC7.html)
NO (1) NO934425L (cg-RX-API-DMAC7.html)
NZ (1) NZ248727A (cg-RX-API-DMAC7.html)
PH (1) PH30158A (cg-RX-API-DMAC7.html)
SK (1) SK142793A3 (cg-RX-API-DMAC7.html)
TW (1) TW240171B (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU674025B2 (en) * 1992-12-04 1996-12-05 Nanosystems L.L.C. Use of ionic cloud point modifiers to prevent particle aggregation during sterilization

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