AU660627B2 - Functionally active selectin-derived peptide for GMP-140 - Google Patents

Functionally active selectin-derived peptide for GMP-140

Info

Publication number
AU660627B2
AU660627B2 AU86207/91A AU8620791A AU660627B2 AU 660627 B2 AU660627 B2 AU 660627B2 AU 86207/91 A AU86207/91 A AU 86207/91A AU 8620791 A AU8620791 A AU 8620791A AU 660627 B2 AU660627 B2 AU 660627B2
Authority
AU
Australia
Prior art keywords
gmp
carbohydrate
peptide
binding
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU86207/91A
Other languages
English (en)
Other versions
AU8620791A (en
Inventor
Rodger P Mcever
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Oklahoma
Original Assignee
University of Oklahoma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Oklahoma filed Critical University of Oklahoma
Publication of AU8620791A publication Critical patent/AU8620791A/en
Priority to AU17731/95A priority Critical patent/AU697488B2/en
Application granted granted Critical
Publication of AU660627B2 publication Critical patent/AU660627B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU86207/91A 1990-07-17 1991-07-17 Functionally active selectin-derived peptide for GMP-140 Ceased AU660627B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU17731/95A AU697488B2 (en) 1990-07-17 1995-04-28 Functionally active selectin-derived peptides and ligand for GMP-140

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55419990A 1990-07-17 1990-07-17
US554199 1990-07-17
US65048491A 1991-02-05 1991-02-05
US650484 1991-02-05
PCT/US1991/005059 WO1992001718A2 (en) 1990-07-17 1991-07-17 Functionally active selectin-derived peptides and ligand for gmp-140

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU17731/95A Division AU697488B2 (en) 1990-07-17 1995-04-28 Functionally active selectin-derived peptides and ligand for GMP-140

Publications (2)

Publication Number Publication Date
AU8620791A AU8620791A (en) 1992-02-18
AU660627B2 true AU660627B2 (en) 1995-07-06

Family

ID=27070521

Family Applications (2)

Application Number Title Priority Date Filing Date
AU86207/91A Ceased AU660627B2 (en) 1990-07-17 1991-07-17 Functionally active selectin-derived peptide for GMP-140
AU17731/95A Ceased AU697488B2 (en) 1990-07-17 1995-04-28 Functionally active selectin-derived peptides and ligand for GMP-140

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU17731/95A Ceased AU697488B2 (en) 1990-07-17 1995-04-28 Functionally active selectin-derived peptides and ligand for GMP-140

Country Status (9)

Country Link
EP (2) EP0714912B1 (enExample)
JP (5) JP3096305B2 (enExample)
AT (1) ATE224911T1 (enExample)
AU (2) AU660627B2 (enExample)
CA (1) CA2086323C (enExample)
DE (1) DE69133120T2 (enExample)
DK (1) DK0714912T3 (enExample)
ES (1) ES2183851T3 (enExample)
WO (1) WO1992001718A2 (enExample)

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US6387884B1 (en) 1990-06-18 2002-05-14 Stanford University Leukocyte homing modulation
US6391857B1 (en) 1990-06-18 2002-05-21 Stanford University Methods and compositions for endothelial binding
NZ240316A (en) * 1990-10-25 1996-12-20 Univ Michigan Compound for treating disease mediated by the elaboration of elam-1 on endothelial cells
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US6309639B1 (en) 1991-02-05 2001-10-30 The Board Of Regents Of The University Of Oklahoma Method for inhibiting an inflammatory response using antibodies to P-selectin glycoprotein ligand
US5807745A (en) * 1991-03-11 1998-09-15 New England Medical Center Hospitals, Inc. Method of inhibiting PADGEM-mediated or ELAM-1-mediated leukocyte adhesion using an inhibitor comprising a Lex core component
AU1926692A (en) * 1991-04-19 1992-11-17 Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for endothelial binding
US6121233A (en) * 1991-04-19 2000-09-19 John L. Magnani Methods for the inhibition of cancer metastasis mediated by endothelial adhesion molecules
WO1992019646A1 (en) * 1991-05-03 1992-11-12 The Rockefeller University Analog of endothelial leukocyte adhesion molecule (elam)
AU2029392A (en) * 1991-05-14 1992-12-30 Board Of Regents Of The University Of Oklahoma, The Peptide inhibitors of inflammation
US5646123A (en) * 1991-06-10 1997-07-08 Alberta Research Council Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
JPH07507040A (ja) * 1991-09-10 1995-08-03 セントコー，インコーポレイテッド セレクチンによって介在される炎症のペプチド阻害剤
WO1993005803A1 (en) * 1991-09-25 1993-04-01 Genetics Institute, Inc. Anti-inflammatory selectin inhibitors
AU3914393A (en) * 1991-12-18 1994-03-15 Board Of Regents Of The University Of Oklahoma, The Peptide inhibitors of inflammation mediated by selectins
ES2152251T3 (es) * 1992-04-30 2001-02-01 Genentech Inc Variantes del dominio lectina de la selectina.
DE69332881T2 (de) * 1992-05-05 2004-01-29 Aeres Biomedical Ltd Antikörper gegen p-selectin und ihre verwendung
US6033667A (en) * 1992-05-05 2000-03-07 Cytel Corporation Method for detecting the presence of P-selectin
US5728802A (en) * 1992-05-06 1998-03-17 Affymax Technologies N.V. Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1 (ELAM-1)
US5643873A (en) * 1992-05-06 1997-07-01 Affymax Technologies N.V. Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
US5648458A (en) * 1992-05-06 1997-07-15 Affymax Technologies N.V. Peptides and compounds that bind to ELAM-1
CA2136428A1 (en) * 1992-05-28 1993-12-09 George A. Heavner Peptide inhibitors of selectin binding
CA2136844A1 (en) * 1992-05-28 1993-12-09 George A. Heavner Peptide inhibitors of selectin binding
US5440015A (en) * 1992-07-21 1995-08-08 Glycomed Incorporated Selectin peptide medicaments for treating disease
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DE69331331T2 (de) 1992-10-02 2002-08-14 Alberta Research Council, Edmonton Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide
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US5843707A (en) * 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
EP0668907A1 (en) * 1992-11-16 1995-08-30 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for p-selectin and methods of use thereof
WO1994014836A1 (en) * 1992-12-18 1994-07-07 Centocor, Inc. Peptide inhibitors of selectin binding
US5976540A (en) * 1993-05-17 1999-11-02 T Cell Sciences, Inc. Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
WO1994026786A1 (en) 1993-05-17 1994-11-24 T Cell Sciences, Inc. Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
US5856300A (en) * 1994-05-12 1999-01-05 T Cell Sciences, Inc. Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
US5750508A (en) * 1993-06-16 1998-05-12 Glycomed Incorporated Sialic acid/fucose based medicaments
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US8895510B2 (en) 2008-04-08 2014-11-25 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
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BR112020013198A2 (pt) 2017-12-29 2020-12-01 Glycomimetics, Inc. inibidores heterobifuncionais de e-selectina e galectina-3
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Also Published As

Publication number Publication date
JP2004002444A (ja) 2004-01-08
AU8620791A (en) 1992-02-18
CA2086323C (en) 2002-05-14
EP0544815A1 (en) 1993-06-09
DK0714912T3 (da) 2003-02-03
EP0714912A3 (en) 1996-06-26
JP2005255691A (ja) 2005-09-22
WO1992001718A2 (en) 1992-02-06
JPH05509330A (ja) 1993-12-22
DE69133120D1 (de) 2002-10-31
JP2001197899A (ja) 2001-07-24
AU697488B2 (en) 1998-10-08
JPH11147900A (ja) 1999-06-02
ES2183851T3 (es) 2003-04-01
AU1773195A (en) 1995-07-06
WO1992001718A3 (en) 1992-05-14
JP3096305B2 (ja) 2000-10-10
EP0714912A2 (en) 1996-06-05
CA2086323A1 (en) 1992-01-18
DE69133120T2 (de) 2003-05-15
EP0714912B1 (en) 2002-09-25
ATE224911T1 (de) 2002-10-15

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