AU637777B2 - Antibacterial antiplaque oral composition containing novel styrene-phosphonic acid copolymer - Google Patents
Antibacterial antiplaque oral composition containing novel styrene-phosphonic acid copolymer Download PDFInfo
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- AU637777B2 AU637777B2 AU46771/89A AU4677189A AU637777B2 AU 637777 B2 AU637777 B2 AU 637777B2 AU 46771/89 A AU46771/89 A AU 46771/89A AU 4677189 A AU4677189 A AU 4677189A AU 637777 B2 AU637777 B2 AU 637777B2
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- Australia
- Prior art keywords
- phosphonic acid
- aea
- polymer
- retention
- enhancing
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- 229920001577 copolymer Polymers 0.000 title claims description 21
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- 230000002882 anti-plaque Effects 0.000 title description 12
- 229920000642 polymer Polymers 0.000 claims description 30
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- 239000000178 monomer Substances 0.000 claims description 15
- PGKQTZHDCHKDQK-UHFFFAOYSA-N 2-phenylethenylphosphonic acid Chemical compound OP(O)(=O)C=CC1=CC=CC=C1 PGKQTZHDCHKDQK-UHFFFAOYSA-N 0.000 claims description 13
- ZTWTYVWXUKTLCP-UHFFFAOYSA-N vinylphosphonic acid Chemical compound OP(O)(=O)C=C ZTWTYVWXUKTLCP-UHFFFAOYSA-N 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 3
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- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 description 18
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- 125000003118 aryl group Chemical group 0.000 description 5
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- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- UPBDXRPQPOWRKR-UHFFFAOYSA-N furan-2,5-dione;methoxyethene Chemical compound COC=C.O=C1OC(=O)C=C1 UPBDXRPQPOWRKR-UHFFFAOYSA-N 0.000 description 1
- 125000002541 furyl group Chemical group 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 229920000578 graft copolymer Polymers 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- KUQWZSZYIQGTHT-UHFFFAOYSA-N hexa-1,5-diene-3,4-diol Chemical compound C=CC(O)C(O)C=C KUQWZSZYIQGTHT-UHFFFAOYSA-N 0.000 description 1
- 229940051250 hexylene glycol Drugs 0.000 description 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 150000002688 maleic acid derivatives Chemical class 0.000 description 1
- 150000002689 maleic acids Chemical class 0.000 description 1
- 229910052751 metal Chemical class 0.000 description 1
- 239000002184 metal Chemical class 0.000 description 1
- 125000005395 methacrylic acid group Chemical group 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 description 1
- ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical compound O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 description 1
- 125000005499 phosphonyl group Chemical group 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000744 poly(arginines) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229950005134 polycarbophil Drugs 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920001444 polymaleic acid Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- XWCIXXXLOAAWPU-UHFFFAOYSA-N prop-1-enylphosphonic acid Chemical compound CC=CP(O)(O)=O XWCIXXXLOAAWPU-UHFFFAOYSA-N 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 125000004076 pyridyl group Chemical group 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- WSWCOQWTEOXDQX-MQQKCMAXSA-N sorbic acid group Chemical group C(\C=C\C=C\C)(=O)O WSWCOQWTEOXDQX-MQQKCMAXSA-N 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000003460 sulfonic acids Chemical group 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- CIHOLLKRGTVIJN-UHFFFAOYSA-N tert‐butyl hydroperoxide Chemical compound CC(C)(C)OO CIHOLLKRGTVIJN-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 125000004862 thiobutyl group Chemical group 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- VSJRDSLPNMGNFG-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate;trihydrate Chemical compound O.O.O.[Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O VSJRDSLPNMGNFG-UHFFFAOYSA-H 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000012178 vegetable wax Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 229940117958 vinyl acetate Drugs 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 125000005023 xylyl group Chemical group 0.000 description 1
- 229940085658 zinc citrate trihydrate Drugs 0.000 description 1
- 150000003752 zinc compounds Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8164—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers, e.g. poly (methyl vinyl ether-co-maleic anhydride)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8117—Homopolymers or copolymers of aromatic olefines, e.g. polystyrene; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39860689A | 1989-08-25 | 1989-08-25 | |
| US39860589A | 1989-08-25 | 1989-08-25 | |
| US39966989A | 1989-08-25 | 1989-08-25 | |
| US398592 | 1989-08-25 | ||
| US398566 | 1989-08-25 | ||
| US398605 | 1989-08-25 | ||
| US399669 | 1989-08-25 | ||
| US07/398,566 US5032386A (en) | 1988-12-29 | 1989-08-25 | Antiplaque antibacterial oral composition |
| US398606 | 1989-08-25 | ||
| US07/398,592 US5188821A (en) | 1987-01-30 | 1989-08-25 | Antibacterial antiplaque oral composition mouthwash or liquid dentifrice |
| US41068289A | 1989-09-21 | 1989-09-21 | |
| US410682 | 1989-09-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4677189A AU4677189A (en) | 1991-02-28 |
| AU637777B2 true AU637777B2 (en) | 1993-06-10 |
Family
ID=27559923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU46771/89A Ceased AU637777B2 (en) | 1989-08-25 | 1989-12-13 | Antibacterial antiplaque oral composition containing novel styrene-phosphonic acid copolymer |
Country Status (16)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0523776A3 (en) * | 1991-07-17 | 1993-05-26 | Unilever N.V. | Oral compositions containing a phosphopeptide |
| US5200554A (en) * | 1992-01-21 | 1993-04-06 | Nasman Jan Anders H | Bisphosphonic acid derivatives and their use |
| GB9306109D0 (en) * | 1993-03-24 | 1993-05-12 | Albright & Wilson | Bulk polymerisation process and product |
| JP3532692B2 (ja) * | 1995-04-03 | 2004-05-31 | 日本油脂株式会社 | ホスホリルコリン基含有重合体水性溶液および製造方法 |
| DE10017997A1 (de) | 2000-04-11 | 2001-10-18 | Henkel Kgaa | Belaghemmendes flüssiges Zahnreinigungsgel |
| US20060140881A1 (en) * | 2004-12-22 | 2006-06-29 | Guofeng Xu | Oral care compositions containing flavonoids and flavans |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0115410A2 (en) * | 1983-01-21 | 1984-08-08 | Kuraray Co., Ltd. | Adhesive compositions |
| AU4676989A (en) * | 1988-12-29 | 1990-07-05 | Colgate-Palmolive Company, The | Antiplaque antibacterial oral composition |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA717486B (en) * | 1970-11-19 | 1973-06-27 | Colgate Palmolive Co | Treatment of teeth |
| DE2060218C3 (de) * | 1970-12-08 | 1980-06-04 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 1 -Phenyl-vinyl-1 -phosphonsaure |
| US3763122A (en) * | 1972-03-07 | 1973-10-02 | Basf Wyandotte Corp | Acrylamide styrene phosphonic acid copolymers as paper additives |
| US4022880A (en) * | 1973-09-26 | 1977-05-10 | Lever Brothers Company | Anticalculus composition |
| DE2455624A1 (de) * | 1974-11-23 | 1976-05-26 | Hoechst Ag | Verfahren zur nachbehandlung von phosphatierten metalloberflaechen |
| DE2615489A1 (de) * | 1976-04-09 | 1977-10-27 | Hoechst Ag | Verfahren zur nachbehandlung von phosphatierten metalloberflaechen |
| DE3130628A1 (de) * | 1981-08-01 | 1983-02-17 | Röhm GmbH, 6100 Darmstadt | Substituierte 1-phenyl-vinyl-1-phosphonsaeuren und ihre verwendung |
| DE3445695A1 (de) * | 1983-12-28 | 1985-07-11 | Colgate-Palmolive Co., New York, N.Y. | Mittel zur oral-dentalen anwendung gegen plaque und gingivitis |
| GB8411841D0 (en) * | 1984-05-09 | 1984-06-13 | Unilever Plc | Oral compositions |
| GB8629640D0 (en) * | 1986-12-11 | 1987-01-21 | Beecham Group Plc | Composition & method |
-
1989
- 1989-12-13 AU AU46771/89A patent/AU637777B2/en not_active Ceased
- 1989-12-13 IL IL92693A patent/IL92693A0/xx not_active IP Right Cessation
- 1989-12-15 NZ NZ231812A patent/NZ231812A/en unknown
- 1989-12-21 GB GB8928954A patent/GB2235201B/en not_active Expired - Fee Related
- 1989-12-22 DE DE3942641A patent/DE3942641C2/de not_active Expired - Fee Related
- 1989-12-26 AR AR89315844A patent/AR244259A1/es active
- 1989-12-27 CH CH4654/89A patent/CH679674A5/de not_active IP Right Cessation
- 1989-12-27 PT PT92735A patent/PT92735B/pt not_active IP Right Cessation
- 1989-12-27 MY MYPI89001860A patent/MY107361A/en unknown
- 1989-12-27 CA CA002006707A patent/CA2006707C/en not_active Expired - Fee Related
- 1989-12-28 CZ CS897511A patent/CZ281211B6/cs not_active IP Right Cessation
- 1989-12-28 FR FR8917372A patent/FR2651235A1/fr not_active Withdrawn
- 1989-12-28 DK DK671189A patent/DK671189A/da not_active Application Discontinuation
- 1989-12-29 NL NL8903188A patent/NL8903188A/nl not_active Application Discontinuation
-
1990
- 1990-01-04 JP JP02000213A patent/JP3112914B2/ja not_active Expired - Fee Related
-
1997
- 1997-05-29 HK HK70497A patent/HK70497A/xx not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0115410A2 (en) * | 1983-01-21 | 1984-08-08 | Kuraray Co., Ltd. | Adhesive compositions |
| AU4676989A (en) * | 1988-12-29 | 1990-07-05 | Colgate-Palmolive Company, The | Antiplaque antibacterial oral composition |
| GB2227660A (en) * | 1988-12-29 | 1990-08-08 | Colgate Palmolive Co | Antiplaque antibacterial oral composition |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3942641A1 (de) | 1991-02-28 |
| JP3112914B2 (ja) | 2000-11-27 |
| FR2651235A1 (enrdf_load_stackoverflow) | 1991-03-01 |
| NZ231812A (en) | 1991-09-25 |
| PT92735A (pt) | 1991-04-18 |
| PT92735B (pt) | 1996-02-29 |
| GB2235201A (en) | 1991-02-27 |
| IL92693A0 (en) | 1990-09-17 |
| DK671189D0 (da) | 1989-12-28 |
| CH679674A5 (enrdf_load_stackoverflow) | 1992-03-31 |
| HK70497A (en) | 1997-06-06 |
| CZ751189A3 (en) | 1996-02-14 |
| DK671189A (da) | 1991-02-26 |
| NL8903188A (nl) | 1991-03-18 |
| CA2006707C (en) | 2001-01-30 |
| CA2006707A1 (en) | 1991-02-25 |
| CZ281211B6 (cs) | 1996-07-17 |
| AR244259A1 (es) | 1993-10-29 |
| DE3942641C2 (de) | 2002-08-08 |
| GB2235201B (en) | 1994-02-16 |
| AU4677189A (en) | 1991-02-28 |
| JPH0383910A (ja) | 1991-04-09 |
| GB8928954D0 (en) | 1990-02-28 |
| MY107361A (en) | 1995-11-30 |
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