AU599575B2 - Mutual separation of proteins - Google Patents

Mutual separation of proteins Download PDF

Info

Publication number
AU599575B2
AU599575B2 AU47496/85A AU4749685A AU599575B2 AU 599575 B2 AU599575 B2 AU 599575B2 AU 47496/85 A AU47496/85 A AU 47496/85A AU 4749685 A AU4749685 A AU 4749685A AU 599575 B2 AU599575 B2 AU 599575B2
Authority
AU
Australia
Prior art keywords
protein
met
leu
ser
ile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU47496/85A
Other languages
English (en)
Other versions
AU4749685A (en
Inventor
Koichi Kato
Kenji Kawahara
Takao Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1984/000460 external-priority patent/WO1986002068A1/ja
Priority claimed from PCT/JP1985/000274 external-priority patent/WO1986007063A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AU4749685A publication Critical patent/AU4749685A/en
Application granted granted Critical
Publication of AU599575B2 publication Critical patent/AU599575B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis
    • C07K1/28—Isoelectric focusing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU47496/85A 1984-09-26 1985-09-16 Mutual separation of proteins Ceased AU599575B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
WOJP8400460 1984-09-26
PCT/JP1984/000460 WO1986002068A1 (fr) 1984-09-26 1984-09-26 Separation mutuelle de proteines
WOJP8500274 1985-05-21
PCT/JP1985/000274 WO1986007063A1 (fr) 1985-05-21 1985-05-21 Separation de deux proteines

Publications (2)

Publication Number Publication Date
AU4749685A AU4749685A (en) 1986-04-10
AU599575B2 true AU599575B2 (en) 1990-07-26

Family

ID=26425064

Family Applications (1)

Application Number Title Priority Date Filing Date
AU47496/85A Ceased AU599575B2 (en) 1984-09-26 1985-09-16 Mutual separation of proteins

Country Status (8)

Country Link
EP (1) EP0176299B1 (enExample)
JP (1) JPH0694476B2 (enExample)
KR (1) KR860002526A (enExample)
AU (1) AU599575B2 (enExample)
DE (1) DE3585657D1 (enExample)
DK (1) DK431485A (enExample)
IL (1) IL76360A0 (enExample)
NZ (1) NZ213615A (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3526096A1 (de) * 1985-07-22 1987-01-22 Basf Ag Verfahren zur reinigung von htnf
CN86104525A (zh) * 1985-07-31 1987-02-25 武田药品工业株式会社 人类白细胞介素-2的分析方法和试剂
DK585886A (da) * 1985-12-24 1987-06-25 Takeda Chemical Industries Ltd Immunstimulerende middel og anvendelse deraf
AU626008B2 (en) * 1987-10-23 1992-07-23 Schering Corporation Method of purifying protein
US5451662A (en) * 1987-10-23 1995-09-19 Schering Corporation Method of purifying protein
US5250296A (en) * 1990-11-29 1993-10-05 Takeda Chemical Industries, Ltd. Immunostimulant agent containing interleukin-2 and 5'-deoxy-5-fluorouridine
US5416071A (en) * 1991-03-12 1995-05-16 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release containing epo and hyaluronic acid
HUP0400389A3 (en) 2001-03-29 2008-03-28 Schering Corp Aryl oxime-piperazines useful as ccr5 antagonists and pharmaceutical compositions containing them
KR20050119652A (ko) 2003-03-24 2005-12-21 에프. 호프만-라 로슈 아게 역전사 효소 저해제로서의 벤질-피리다진온
EP1940781A1 (en) 2005-10-19 2008-07-09 F.Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
EP2057125B1 (en) 2006-08-16 2011-03-30 F. Hoffmann-La Roche AG Non-nucleoside reverse transcriptase inhibitors
MX2009005881A (es) 2006-12-13 2009-06-12 Hoffmann La Roche Derivados de 2-(piperidin-4-il)-4-fenoxi o fenilamino-pirimidina como inhibidores de la transcriptasa inversa no nucleosida.
CA2687747C (en) 2007-05-30 2015-11-17 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
EP2225239B1 (en) 2007-12-21 2014-10-22 F. Hoffmann-La Roche AG Heterocyclic antiviral compounds
CA2773428A1 (en) 2009-09-10 2011-03-17 Lonza Biologics Plc Method and system for polypeptide purification

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020290A1 (de) * 1979-05-31 1980-12-10 Schering Aktiengesellschaft Verfahren zur spezifischen Abspaltung von Proteinsequenzen aus Proteinen
EP0127305A1 (en) * 1983-04-25 1984-12-05 Genentech, Inc. Human growth hormone, and process for its production, expression vehicles for producing pre HGH and host cells transformed thereby
AU4773985A (en) * 1984-08-16 1986-03-07 Savient Pharmaceuticals, Inc. Method of removing n-terminal amino acid residues using aeromonas aminopeptidases

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1346A (en) * 1980-01-08 1987-01-16 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human interferon-like polypeptides
CH651308A5 (de) 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
JPS58116498A (ja) * 1981-12-28 1983-07-11 Takeda Chem Ind Ltd Ｉｌ‐２をコードする新規伝令ｒｎａの製造法
CA1210714A (en) * 1982-03-23 1986-09-02 Alan Sloma .alpha.-INTERFERON GX-1
CA1341562C (en) * 1982-03-31 2007-11-27 Tadatsugu Taniguchi Gene coded for interleukin-2 polypeptide, recombinant dna carrying the said gene, a living cell line possessing the recombinant dna, and method for producing interleukin-2 using the said cell
EP0091539B2 (en) 1982-03-31 1996-11-27 Ajinomoto Co., Inc. Gene coding for interleukin-2 polypeptide, recombinant DNA carrying said gene, cell lines possessing the recombinant DNA,and method for producing interleukin-2 using said cells
ATE37564T1 (de) * 1982-04-20 1988-10-15 Sloan Kettering Inst Cancer Reinigung von interleukin-2.
JPS58198293A (ja) * 1982-05-12 1983-11-18 Shionogi & Co Ltd インタ−ロイキン等免疫調節因子の製造方法
FI82266C (fi) 1982-10-19 1991-02-11 Cetus Corp Foerfarande foer framstaellning av il-2 -mutein.
IL90047A (en) 1982-10-19 1992-12-01 Cetus Oncology Corp Cysteine-depleted biologically active muteins other than interferon - '
JPS59116231A (ja) * 1982-12-13 1984-07-05 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ 抗−インタ−ロイキン−２単クロ−ン抗体
ZA841395B (en) * 1983-03-03 1984-10-31 Hoffmann La Roche Purification of interferon
WO1985000606A1 (fr) 1983-07-19 1985-02-14 Takeda Chemical Industries, Ltd. Il-2 humaine et son procede de preparation
JPS60115528A (ja) 1983-11-28 1985-06-22 Takeda Chem Ind Ltd ヒトインタ―ロイキン―２蛋白質を含有する抗腫瘍用または免疫機能低下疾患治療用組成物
JPS60126088A (ja) 1983-12-13 1985-07-05 Takeda Chem Ind Ltd 新規ｄνａおよびその用途
JPS60172999A (ja) * 1983-12-20 1985-09-06 Suntory Ltd 新規な塩基性ポリペプチドおよびその製造法
NZ210634A (en) * 1983-12-23 1989-05-29 Hoffmann La Roche Purification of recombinant human interleukin - 2; pharmaceutical compositions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020290A1 (de) * 1979-05-31 1980-12-10 Schering Aktiengesellschaft Verfahren zur spezifischen Abspaltung von Proteinsequenzen aus Proteinen
EP0127305A1 (en) * 1983-04-25 1984-12-05 Genentech, Inc. Human growth hormone, and process for its production, expression vehicles for producing pre HGH and host cells transformed thereby
AU4773985A (en) * 1984-08-16 1986-03-07 Savient Pharmaceuticals, Inc. Method of removing n-terminal amino acid residues using aeromonas aminopeptidases

Also Published As

Publication number Publication date
EP0176299A2 (en) 1986-04-02
KR860002526A (ko) 1986-04-26
IL76360A0 (en) 1986-01-31
NZ213615A (en) 1989-08-29
JPS6178799A (ja) 1986-04-22
DE3585657D1 (de) 1992-04-23
EP0176299A3 (en) 1987-07-15
DK431485A (da) 1986-03-27
DE3585657A1 (enExample) 1992-04-23
AU4749685A (en) 1986-04-10
EP0176299B1 (en) 1992-03-18
DK431485D0 (da) 1985-09-24
JPH0694476B2 (ja) 1994-11-24

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