AU568643B2 - 17(isocyano-sulfonyl methylene)-steroids and 17(formamido- sulfonyl methylene)-steroids - Google Patents

17(isocyano-sulfonyl methylene)-steroids and 17(formamido- sulfonyl methylene)-steroids

Info

Publication number
AU568643B2
AU568643B2 AU27133/84A AU2713384A AU568643B2 AU 568643 B2 AU568643 B2 AU 568643B2 AU 27133/84 A AU27133/84 A AU 27133/84A AU 2713384 A AU2713384 A AU 2713384A AU 568643 B2 AU568643 B2 AU 568643B2
Authority
AU
Australia
Prior art keywords
group
groups
substituted
steroids
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27133/84A
Other languages
English (en)
Other versions
AU2713384A (en
Inventor
Adriaan Marinus Van Leusen
Albert Mattheus Van Leusen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of AU2713384A publication Critical patent/AU2713384A/en
Application granted granted Critical
Publication of AU568643B2 publication Critical patent/AU568643B2/en
Assigned to ROUSSEL-UCLAF reassignment ROUSSEL-UCLAF Alteration of Name(s) in Register under S187 Assignors: GIST-BROCADES N.V.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/005—3 membered carbocyclic rings in position 12
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU27133/84A 1983-04-29 1984-04-19 17(isocyano-sulfonyl methylene)-steroids and 17(formamido- sulfonyl methylene)-steroids Ceased AU568643B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP83200616A EP0123734A1 (en) 1983-04-29 1983-04-29 17-(Isocyano-sulfonylmethylene)-steroids, 17-(formamido-sulfonylmethylene)-steroids and their preparation
EP83200616 1983-04-29

Publications (2)

Publication Number Publication Date
AU2713384A AU2713384A (en) 1984-11-01
AU568643B2 true AU568643B2 (en) 1988-01-07

Family

ID=8190949

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27133/84A Ceased AU568643B2 (en) 1983-04-29 1984-04-19 17(isocyano-sulfonyl methylene)-steroids and 17(formamido- sulfonyl methylene)-steroids

Country Status (17)

Country Link
US (1) US4647410A (enExample)
EP (2) EP0123734A1 (enExample)
JP (2) JPS59206399A (enExample)
KR (1) KR860001469B1 (enExample)
AU (1) AU568643B2 (enExample)
CA (1) CA1257249A (enExample)
DE (1) DE3461381D1 (enExample)
DK (2) DK166545B1 (enExample)
ES (2) ES8608537A1 (enExample)
FI (1) FI82061C (enExample)
GR (1) GR81997B (enExample)
HU (2) HU193207B (enExample)
IE (1) IE57328B1 (enExample)
IL (1) IL71658A (enExample)
NO (1) NO167093C (enExample)
NZ (1) NZ207985A (enExample)
PT (1) PT78503B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123735A1 (en) * 1983-04-29 1984-11-07 Gist-Brocades N.V. New process for the preparation of 20-keto-delta-16-steroids and new intermediate compounds formed in this process
HU208437B (en) * 1988-04-08 1993-10-28 Roussel Uclaf Process for producing 9-alpha-hydroxy- -17-methylene-steroides for synthetizing corticosteroides
HU226413B1 (en) * 1991-06-25 2008-11-28 Aventis Pharma Sa Novel 16-(nitro-substituted methyl)pregna-1,4-dien-3,20-dion derivatives and process for producing them
FR2681069B1 (fr) * 1991-09-06 1995-04-28 Roussel Uclaf Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.
FR2683530B1 (fr) * 1991-11-08 1994-01-21 Roussel Uclaf Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
WO1997021720A2 (en) 1995-12-11 1997-06-19 G.D. Searle And Co. Processes for preparation of 7 alpha-carboxyl 9,11-epoxy steroids and intermediates useful therein and a general process for the epoxidation of olifinic double bonds
US6887991B1 (en) 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
NZ336004A (en) 1996-12-11 2001-04-27 G Process for preparation of 3-keto-7-alpha-alkoxycarbonyl substituted delta-4,5-steroid by reacting 4,5-dihydro-5,7-lactone steroid substrate in the presence of a base
US6372712B1 (en) 1998-05-22 2002-04-16 The Board Of Trustees Of The Leland Stanford Jr. University Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
EP2287721A3 (en) 1999-11-02 2011-04-06 Canon Kabushiki Kaisha Print control method and apparatus
US7235655B2 (en) 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
CN105481924B (zh) * 2015-11-24 2017-08-15 浙江省诸暨合力化学对外贸易有限公司 一种黄体酮的制备方法
US20240368212A1 (en) * 2021-08-26 2024-11-07 Brandeis University Selective isonitrile inhibitors of cytochrome p450 subtypes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807631A (nl) * 1978-07-17 1980-01-21 Gist Brocades Nv Isocyanoderivaten en hun bereiding.
FR2462445A1 (fr) * 1979-07-31 1981-02-13 Roussel Uclaf Nouveaux derives 17-/(hydroxymethyl) (formamido) methylene/steroides, leur procede de preparation et leur application a l'introduction de la chaine laterale hydroxyacetyle
FR2486947A1 (fr) * 1980-07-15 1982-01-22 Roussel Uclaf Nouveaux derives steroides 20-isonitriles 17(20) insatures, leur procede de preparation et leur application a la preparation des steroides 17a-hydroxy 20-ceto

Also Published As

Publication number Publication date
JPH0559097A (ja) 1993-03-09
GR81997B (enExample) 1984-12-12
DK166831B1 (da) 1993-07-19
IL71658A0 (en) 1984-07-31
PT78503A (en) 1984-05-01
HU193207B (en) 1987-08-28
AU2713384A (en) 1984-11-01
PT78503B (en) 1986-05-20
DK22192D0 (da) 1992-02-21
EP0123734A1 (en) 1984-11-07
JPH053478B2 (enExample) 1993-01-14
FI841679A7 (fi) 1984-10-30
ES8608537A1 (es) 1986-07-16
DK212184D0 (da) 1984-04-27
NO167093B (no) 1991-06-24
IE841038L (en) 1984-10-29
US4647410A (en) 1987-03-03
FI82061B (fi) 1990-09-28
DK212184A (da) 1984-10-30
EP0124934B1 (en) 1986-11-20
DE3461381D1 (en) 1987-01-08
ES553609A0 (es) 1987-11-01
DK22192A (da) 1992-02-21
CA1257249A (en) 1989-07-11
FI841679A0 (fi) 1984-04-27
JPS59206399A (ja) 1984-11-22
HU194277B (en) 1988-01-28
EP0124934A1 (en) 1984-11-14
ES8800263A1 (es) 1987-11-01
FI82061C (fi) 1991-01-10
DK166545B1 (da) 1993-06-07
IE57328B1 (en) 1992-07-29
NO841700L (no) 1984-10-30
HUT34220A (en) 1985-02-28
JPH0717673B2 (ja) 1995-03-01
NZ207985A (en) 1986-11-12
ES532029A0 (es) 1986-07-16
KR860001469B1 (ko) 1986-09-26
KR840008461A (ko) 1984-12-15
IL71658A (en) 1988-03-31
NO167093C (no) 1991-10-02

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