AU562104B2 - Substituted ureas and thioureas as sweeteners - Google Patents

Substituted ureas and thioureas as sweeteners

Info

Publication number
AU562104B2
AU562104B2 AU19165/83A AU1916583A AU562104B2 AU 562104 B2 AU562104 B2 AU 562104B2 AU 19165/83 A AU19165/83 A AU 19165/83A AU 1916583 A AU1916583 A AU 1916583A AU 562104 B2 AU562104 B2 AU 562104B2
Authority
AU
Australia
Prior art keywords
group
lone
carbon atoms
electron pair
pair donor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU19165/83A
Other languages
English (en)
Other versions
AU1916583A (en
Inventor
Claude Nofre
Jean-Marie Tinti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Claude Bernard Lyon 1
Original Assignee
Universite Claude Bernard Lyon 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Claude Bernard Lyon 1 filed Critical Universite Claude Bernard Lyon 1
Publication of AU1916583A publication Critical patent/AU1916583A/en
Application granted granted Critical
Publication of AU562104B2 publication Critical patent/AU562104B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Tea And Coffee (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • General Preparation And Processing Of Foods (AREA)
AU19165/83A 1982-09-17 1983-09-15 Substituted ureas and thioureas as sweeteners Ceased AU562104B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8215832 1982-09-17
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese

Publications (2)

Publication Number Publication Date
AU1916583A AU1916583A (en) 1984-03-22
AU562104B2 true AU562104B2 (en) 1987-05-28

Family

ID=9277590

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19165/83A Ceased AU562104B2 (en) 1982-09-17 1983-09-15 Substituted ureas and thioureas as sweeteners

Country Status (16)

Country Link
US (1) US4645678A (cg-RX-API-DMAC7.html)
EP (1) EP0107597B1 (cg-RX-API-DMAC7.html)
JP (1) JPS5973559A (cg-RX-API-DMAC7.html)
AT (1) ATE18236T1 (cg-RX-API-DMAC7.html)
AU (1) AU562104B2 (cg-RX-API-DMAC7.html)
CA (1) CA1244007A (cg-RX-API-DMAC7.html)
DE (1) DE3362324D1 (cg-RX-API-DMAC7.html)
DK (1) DK424783A (cg-RX-API-DMAC7.html)
ES (1) ES525680A0 (cg-RX-API-DMAC7.html)
FR (1) FR2533210A1 (cg-RX-API-DMAC7.html)
GR (1) GR81273B (cg-RX-API-DMAC7.html)
IL (1) IL69733A0 (cg-RX-API-DMAC7.html)
NO (1) NO158418C (cg-RX-API-DMAC7.html)
NZ (1) NZ205616A (cg-RX-API-DMAC7.html)
PT (1) PT77351B (cg-RX-API-DMAC7.html)
ZA (1) ZA836892B (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU571773B2 (en) * 1985-03-19 1988-04-21 Universite Claude Bernard - Lyon 1 Sweetening agents containing =n-cn group
AU620796B2 (en) * 1986-12-03 1992-02-27 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2575163B1 (fr) * 1984-12-20 1987-03-20 Sanofi Sa Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
US4833128A (en) * 1984-12-28 1989-05-23 Neil Solomon Dietary supplement
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2608379B1 (fr) * 1986-12-23 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides n-phenylguanidinoacetique et n-phenylethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
FR2606404B2 (fr) * 1986-04-10 1991-11-22 Univ Claude Bernard Lyon Nouveaux composes chimiques derivant de l'acide phenylguanidinoacetique et leur utilisation comme agents edulcorants
JPS61260052A (ja) * 1985-05-14 1986-11-18 Ajinomoto Co Inc 新規アミノ酸誘導体および甘味剤
KR870008526A (ko) * 1986-03-13 1987-10-19 원본미기재 감미료 및 그 제조방법
FR2609603B1 (fr) * 1987-01-15 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
WO1989000563A1 (en) * 1987-07-17 1989-01-26 The Nutrasweet Company High potency sweetening agents
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
FR2624698A1 (fr) * 1987-12-18 1989-06-23 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-aminomalonyl ou aminosuccinyl amides utiles comme agents edulcorants
FR2630304B1 (fr) * 1988-04-22 1990-08-31 Bernard Lyon I Universite Clau Derives n-hydrocarbones des acides aspartique et glutamique alpha-monoamides utiles comme agents edulcorants
WO1990002112A1 (en) * 1988-08-23 1990-03-08 The Nutrasweet Company Substituted aryl ureas as high potency sweeteners
US5266717A (en) * 1989-04-03 1993-11-30 Glenn Roy N-(sulfomethyl)-N'arylureas
US4994490A (en) * 1989-04-03 1991-02-19 The Nutrasweet Company Novel N-(sulfomethyl)-N'-arylureas
FR2653303B1 (fr) * 1989-10-24 1992-09-18 Noffre Claude Agents edulcorants de grande stabilite derivant des acides l-aspartique et l-glutamique n-hydrocarbones 1-oxo-2-ramifies.
KR927003625A (ko) * 1990-02-09 1992-12-18 미셀 모르뱅 N-페닐-n-아세트아미도 글리신아미드, 제조방법 및 이들을 함유하는 약물
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
WO1996028416A1 (en) * 1995-03-14 1996-09-19 Daiichi Pharmaceutical Co., Ltd. Aminophenol derivatives
MY121054A (en) * 1998-04-08 2005-12-30 Smithkline Beecham Corp Calcilytic compounds as calcium receptor antagonists.
SK286552B6 (sk) * 1998-04-09 2008-12-05 Ajinomoto Co., Inc. Deriváty esterov aspartylových dipeptidov, sladidlo s ich obsahom a jeho použitie
AU7822398A (en) * 1998-06-05 1999-12-20 Wm. Wrigley Jr. Company Method of controlling release of n-substituted derivatives of aspartame in chewing gum and gum produced thereby
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
RU2192430C2 (ru) * 1998-06-26 2002-11-10 Адзиномото Ко., Инк. Новые производные аспартилового дипептидного эфира и подсластители
CZ2001974A3 (cs) 1998-09-18 2001-08-15 Ajinomoto Co., Inc. N-alkylaspartyldipeptidový esterový derivát a sladidlo
US20030018203A1 (en) * 2002-07-17 2003-01-23 Largo Maria Amparo Calcilytic compounds
MY159417A (en) * 2000-01-24 2017-01-13 Smithkline Beecham Corp Calcilytic compounds
US7476399B2 (en) * 2003-08-06 2009-01-13 Senomyx Inc. Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
JP2008530017A (ja) * 2005-02-04 2008-08-07 セノミックス インコーポレイテッド 食料用組成物のための風味調整剤として連結された有機部分を含む分子
EP1850681B1 (en) 2005-02-04 2019-12-18 Firmenich Incorporated Compounds comprising linked hetero aryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions
AR055329A1 (es) * 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
US9101160B2 (en) * 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
DK2526783T3 (en) * 2005-11-23 2017-02-06 Coca Cola Co Natural high-potency sweetener compositions with improved time profile and / or flavor profile
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8435588B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US8945652B2 (en) * 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
US8940350B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US8940351B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Baked goods comprising high-potency sweetener
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US8367138B2 (en) * 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
EP3398452B1 (en) 2006-04-21 2024-10-02 Firmenich Incorporated Comestible compositions comprising high potency savory flavorants
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
JP5647790B2 (ja) 2007-11-16 2015-01-07 株式会社カネカ Ｎ−カルバモイル−ｔｅｒｔ−ロイシンの製造法
MX376348B (es) 2011-10-26 2025-03-07 Allergan Inc Derivados de amida de aminoacidos sustituidos con n-urea como moduladores de receptor de tipo peptido receptor de formilo-1 (fprl-1).
EP3022174B1 (en) * 2013-07-16 2018-09-05 Allergan, Inc. Derivatives of n-urea substituted amino acids as formyl peptide receptor modulators
EP3145916B1 (en) 2014-05-21 2020-02-12 Allergan, Inc. Imidazole derivatives as formyl peptide receptor modulators

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US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3800046A (en) * 1967-04-17 1974-03-26 Searle & Co Artificially sweetened consumable products
GB1258248A (cg-RX-API-DMAC7.html) * 1968-07-17 1971-12-22
US3642491A (en) * 1970-01-12 1972-02-15 Searle & Co Artificially sweetened consumable products
CA1027113A (en) * 1973-04-02 1978-02-28 General Foods Corporation Sweetener solution containing saccharin and aspartane
NL8005006A (nl) * 1980-09-04 1982-04-01 Stamicarbon Dipeptide-zoetstof.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU571773B2 (en) * 1985-03-19 1988-04-21 Universite Claude Bernard - Lyon 1 Sweetening agents containing =n-cn group
AU620796B2 (en) * 1986-12-03 1992-02-27 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives

Also Published As

Publication number Publication date
ZA836892B (en) 1984-05-30
JPS5973559A (ja) 1984-04-25
PT77351B (fr) 1986-03-18
NO833338L (no) 1984-03-19
NZ205616A (en) 1986-03-14
DE3362324D1 (en) 1986-04-03
GR81273B (cg-RX-API-DMAC7.html) 1984-12-11
NO158418C (no) 1988-09-07
DK424783A (da) 1984-03-18
EP0107597A1 (fr) 1984-05-02
IL69733A0 (en) 1983-12-30
US4645678A (en) 1987-02-24
CA1244007A (fr) 1988-11-01
FR2533210A1 (fr) 1984-03-23
FR2533210B1 (cg-RX-API-DMAC7.html) 1984-11-23
ATE18236T1 (de) 1986-03-15
ES8406423A1 (es) 1984-07-01
EP0107597B1 (fr) 1986-02-26
DK424783D0 (da) 1983-09-16
AU1916583A (en) 1984-03-22
PT77351A (fr) 1983-10-01
NO158418B (no) 1988-05-30
ES525680A0 (es) 1984-07-01

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