ATE18236T1 - Chemische verbindungen und verwendung als suessstoff. - Google Patents

Chemische verbindungen und verwendung als suessstoff.

Info

Publication number
ATE18236T1
ATE18236T1 AT83420149T AT83420149T ATE18236T1 AT E18236 T1 ATE18236 T1 AT E18236T1 AT 83420149 T AT83420149 T AT 83420149T AT 83420149 T AT83420149 T AT 83420149T AT E18236 T1 ATE18236 T1 AT E18236T1
Authority
AT
Austria
Prior art keywords
group
lone
carbon atoms
electron pair
pair donor
Prior art date
Application number
AT83420149T
Other languages
English (en)
Inventor
Claude Nofre
Jean-Marie Tinti
Original Assignee
Univ Claude Bernard Lyon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Claude Bernard Lyon filed Critical Univ Claude Bernard Lyon
Application granted granted Critical
Publication of ATE18236T1 publication Critical patent/ATE18236T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Indole Compounds (AREA)
  • Tea And Coffee (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
AT83420149T 1982-09-17 1983-09-15 Chemische verbindungen und verwendung als suessstoff. ATE18236T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese
EP83420149A EP0107597B1 (de) 1982-09-17 1983-09-15 Chemische Verbindungen und Verwendung als Süssstoff

Publications (1)

Publication Number Publication Date
ATE18236T1 true ATE18236T1 (de) 1986-03-15

Family

ID=9277590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83420149T ATE18236T1 (de) 1982-09-17 1983-09-15 Chemische verbindungen und verwendung als suessstoff.

Country Status (16)

Country Link
US (1) US4645678A (de)
EP (1) EP0107597B1 (de)
JP (1) JPS5973559A (de)
AT (1) ATE18236T1 (de)
AU (1) AU562104B2 (de)
CA (1) CA1244007A (de)
DE (1) DE3362324D1 (de)
DK (1) DK424783A (de)
ES (1) ES8406423A1 (de)
FR (1) FR2533210A1 (de)
GR (1) GR81273B (de)
IL (1) IL69733A0 (de)
NO (1) NO158418C (de)
NZ (1) NZ205616A (de)
PT (1) PT77351B (de)
ZA (1) ZA836892B (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
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FR2575163B1 (fr) * 1984-12-20 1987-03-20 Sanofi Sa Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
US4833128A (en) * 1984-12-28 1989-05-23 Neil Solomon Dietary supplement
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
FR2608379B1 (fr) * 1986-12-23 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides n-phenylguanidinoacetique et n-phenylethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
FR2579201B1 (fr) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2606404B2 (fr) * 1986-04-10 1991-11-22 Univ Claude Bernard Lyon Nouveaux composes chimiques derivant de l'acide phenylguanidinoacetique et leur utilisation comme agents edulcorants
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
JPS61260052A (ja) * 1985-05-14 1986-11-18 Ajinomoto Co Inc 新規アミノ酸誘導体および甘味剤
KR870008526A (ko) * 1986-03-13 1987-10-19 원본미기재 감미료 및 그 제조방법
US4818899A (en) * 1986-12-03 1989-04-04 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives
FR2609603B1 (fr) * 1987-01-15 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
AU617121B2 (en) * 1987-07-17 1991-11-21 Nutrasweet Company, The Substituted guanidines containing a tetrazolyl moiety and their use as high potency sweetening agents
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
FR2624698A1 (fr) * 1987-12-18 1989-06-23 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-aminomalonyl ou aminosuccinyl amides utiles comme agents edulcorants
FR2630304B1 (fr) * 1988-04-22 1990-08-31 Bernard Lyon I Universite Clau Derives n-hydrocarbones des acides aspartique et glutamique alpha-monoamides utiles comme agents edulcorants
AU636853B2 (en) * 1988-08-23 1993-05-13 Nutrasweet Company, The Substituted aryl ureas as high potency sweeteners
US4994490A (en) * 1989-04-03 1991-02-19 The Nutrasweet Company Novel N-(sulfomethyl)-N'-arylureas
US5266717A (en) * 1989-04-03 1993-11-30 Glenn Roy N-(sulfomethyl)-N'arylureas
FR2653303B1 (fr) * 1989-10-24 1992-09-18 Noffre Claude Agents edulcorants de grande stabilite derivant des acides l-aspartique et l-glutamique n-hydrocarbones 1-oxo-2-ramifies.
US5382590A (en) * 1990-02-09 1995-01-17 Rhone-Poulenc Rorer S.A. N-phenyl-N-acetamidoglycinamides, their preparation and medicaments containing them
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
WO1996028416A1 (fr) * 1995-03-14 1996-09-19 Daiichi Pharmaceutical Co., Ltd. Derives d'aminophenol
AR018177A1 (es) * 1998-04-08 2001-10-31 Smithkline Beecham Corp Compuestos calciliticos, una composicion farmaceutica que los comprende y el uso de los mismos para la manufactura de un medicamento.
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
DK1083799T3 (da) * 1998-06-05 2011-01-10 Wrigley W M Jun Co Fremgangsmåde til kontrol af frigørelse af N-substituerede derivater af aspartam i tyggegummi og tyggegummi produceret dermed
HUP0103979A3 (en) * 1998-09-18 2003-05-28 Ajinomoto Kk N-alkylaspartyldipeptide ester derivatives and sweeteners
US20030018203A1 (en) * 2002-07-17 2003-01-23 Largo Maria Amparo Calcilytic compounds
MY159417A (en) * 2000-01-24 2017-01-13 Smithkline Beecham Corp Calcilytic compounds
BRPI0413324A (pt) 2003-08-06 2006-10-10 Senomyx Inc receptores de paladar hetero-oligoméricos t1r, linhas de células que expressam os ditos receptores, e compostos de paladar
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
TW200638882A (en) * 2005-02-04 2006-11-16 Senomyx Inc Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
ZA200707482B (en) 2005-02-04 2008-12-31 Senomyx Inc Compounds comprising linked heteroaryl moieties and their use as novel umami flavour modifiers, tastants and taste enhancers for comestible compositions
AR055329A1 (es) * 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
US8945652B2 (en) * 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
US8435588B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
DK2526783T3 (en) * 2005-11-23 2017-02-06 Coca Cola Co Natural high-potency sweetener compositions with improved time profile and / or flavor profile
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8940350B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US9101160B2 (en) * 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US8367138B2 (en) * 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8940351B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Baked goods comprising high-potency sweetener
WO2007124152A2 (en) 2006-04-21 2007-11-01 Senomyx, Inc. Comestible compositions comprising high potency savory flavorants, and processes for producing them
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
JP5647790B2 (ja) 2007-11-16 2015-01-07 株式会社カネカ Ｎ−カルバモイル−ｔｅｒｔ−ロイシンの製造法
AU2012329098B2 (en) 2011-10-26 2017-08-03 Allergan, Inc. Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators
US9428549B2 (en) 2013-07-16 2016-08-30 Allegran, Inc. Derivatives of N-urea substituted amino acids as formyl peptide receptor modulators
EP3145916B1 (de) 2014-05-21 2020-02-12 Allergan, Inc. Imidazolderivate als formylpeptidrezeptormodulatoren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3800046A (en) * 1967-04-17 1974-03-26 Searle & Co Artificially sweetened consumable products
GB1258248A (de) * 1968-07-17 1971-12-22
US3642491A (en) * 1970-01-12 1972-02-15 Searle & Co Artificially sweetened consumable products
CA1027113A (en) * 1973-04-02 1978-02-28 General Foods Corporation Sweetener solution containing saccharin and aspartane
NL8005006A (nl) * 1980-09-04 1982-04-01 Stamicarbon Dipeptide-zoetstof.

Also Published As

Publication number Publication date
IL69733A0 (en) 1983-12-30
CA1244007A (fr) 1988-11-01
DK424783D0 (da) 1983-09-16
AU562104B2 (en) 1987-05-28
GR81273B (de) 1984-12-11
NO158418B (no) 1988-05-30
FR2533210B1 (de) 1984-11-23
AU1916583A (en) 1984-03-22
PT77351B (fr) 1986-03-18
EP0107597B1 (de) 1986-02-26
NO158418C (no) 1988-09-07
DE3362324D1 (en) 1986-04-03
DK424783A (da) 1984-03-18
JPS5973559A (ja) 1984-04-25
EP0107597A1 (de) 1984-05-02
US4645678A (en) 1987-02-24
ES525680A0 (es) 1984-07-01
FR2533210A1 (fr) 1984-03-23
NO833338L (no) 1984-03-19
ES8406423A1 (es) 1984-07-01
PT77351A (fr) 1983-10-01
ZA836892B (en) 1984-05-30
NZ205616A (en) 1986-03-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee