AU544345B2 - Imidazo(1,2-a)pyridine derivatives - Google Patents

Imidazo(1,2-a)pyridine derivatives

Info

Publication number
AU544345B2
AU544345B2 AU76687/81A AU7668781A AU544345B2 AU 544345 B2 AU544345 B2 AU 544345B2 AU 76687/81 A AU76687/81 A AU 76687/81A AU 7668781 A AU7668781 A AU 7668781A AU 544345 B2 AU544345 B2 AU 544345B2
Authority
AU
Australia
Prior art keywords
imidazo
pyridine
methylthiophenyl
methyl
dimethyl acetamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU76687/81A
Other languages
English (en)
Other versions
AU7668781A (en
Inventor
Pascal George
Jean Pierre Kaplan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9247171&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU544345(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of AU7668781A publication Critical patent/AU7668781A/en
Application granted granted Critical
Publication of AU544345B2 publication Critical patent/AU544345B2/en
Assigned to SANOFI-SYNTHELABO reassignment SANOFI-SYNTHELABO Request to Amend Deed and Register Assignors: SYNTHELABO
Assigned to SANOFI-AVENTIS reassignment SANOFI-AVENTIS Request to Amend Deed and Register Assignors: SANOFI-SYNTHELABO
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU76687/81A 1980-10-22 1981-10-21 Imidazo(1,2-a)pyridine derivatives Expired AU544345B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8022537A FR2492382A1 (fr) 1980-10-22 1980-10-22 Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR8022537 1980-10-22

Publications (2)

Publication Number Publication Date
AU7668781A AU7668781A (en) 1983-04-28
AU544345B2 true AU544345B2 (en) 1985-05-23

Family

ID=9247171

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76687/81A Expired AU544345B2 (en) 1980-10-22 1981-10-21 Imidazo(1,2-a)pyridine derivatives

Country Status (22)

Country Link
US (2) US4382938A (enExample)
EP (1) EP0050563B1 (enExample)
JP (1) JPS5798283A (enExample)
AT (1) ATE7393T1 (enExample)
AU (1) AU544345B2 (enExample)
CA (1) CA1157470A (enExample)
DE (1) DE3163524D1 (enExample)
DK (1) DK154429C (enExample)
ES (1) ES8207537A1 (enExample)
FI (1) FI71143C (enExample)
FR (1) FR2492382A1 (enExample)
GR (1) GR74701B (enExample)
IE (1) IE51686B1 (enExample)
IL (1) IL64091A (enExample)
LU (1) LU88228I2 (enExample)
MX (1) MX6463E (enExample)
NL (1) NL930044I2 (enExample)
NO (1) NO155664C (enExample)
NZ (1) NZ198722A (enExample)
OA (1) OA07076A (enExample)
PT (1) PT73863B (enExample)
ZA (1) ZA817297B (enExample)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
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FR2525602A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2568879B1 (fr) * 1984-08-07 1986-12-12 Synthelabo Imidazo(1,2-a)quinolines, leur preparation et leur application en therapeutique
FR2581646B1 (fr) * 1985-05-07 1987-09-18 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
FR2593179B1 (fr) * 1986-01-22 1988-04-01 Synthelabo Derives d'imidazo(1,2-a)quinoleines, leur preparation et leur application en therapeutique
EP0234970B1 (fr) * 1986-01-22 1991-04-17 Synthelabo Dérivés d'acylaminométhyl-3 imidazo[1,2-a]pyridines, leur préparation et leur application en thérapeutique
FR2593817B1 (fr) * 1986-01-31 1988-04-15 Synthelabo Derives de tetrahydro-5,6,7,8 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
FR2599368B1 (fr) * 1986-06-02 1988-08-05 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
FR2600650B1 (fr) * 1986-06-27 1988-09-09 Synthelabo Procede de preparation d'imidazopyridines et composes intermediaires
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
FR2606409B1 (fr) * 1986-11-07 1989-05-05 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
FR2606411B1 (fr) * 1986-11-07 1989-04-07 Synthelabo Imidazopyridine-acetamides, leur preparation et leur application en therapeutique
ES2026666T3 (es) * 1987-03-27 1992-05-01 Synthelabo Procedimiento para preparar derivados de imidazopiridinas.
FR2612927B1 (fr) * 1987-03-27 1989-06-09 Synthelabo Derives d'imidazopyridines, leur preparation et leur application en therapeutique
FR2612928B1 (fr) * 1987-03-27 1989-06-16 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
US5032595A (en) * 1989-11-24 1991-07-16 Fidia-Georgetown Institute For The Neurosciences Method of stimulating steroidogenesis with alpidem
WO1996025414A1 (en) * 1995-02-15 1996-08-22 Pharmacia & Upjohn Company Imidazo[1,2-a]pyridines for the treatment of cns and cardiac diseases
IT1276522B1 (it) * 1995-04-07 1997-10-31 Elena Benincasa Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
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US6333345B1 (en) 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
WO2001078725A2 (en) * 2000-04-13 2001-10-25 Synthon B.V. Modified release formulations containing a hypnotic agent
EP1600159A1 (en) 2000-04-24 2005-11-30 Teva Pharmaceutical Industries Ltd A method for synthesizing different Zolpidem hemitartrate derivatives
ES2277301T3 (es) * 2000-04-24 2007-07-01 Teva Pharmaceutical Industries Ltd. Solvato de hemitartrato de zolpidem.
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WO2002002557A2 (en) * 2000-06-30 2002-01-10 Neurogen Corporation 2-phenylimidazo[1,2-a]pyridine derivatives: a new class of gaba brain receptor ligands
IT1318624B1 (it) * 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
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US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
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KR100433502B1 (ko) * 2001-10-10 2004-06-07 철 양 확장부가 형성된 종이컵
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US7385056B2 (en) * 2002-12-18 2008-06-10 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
US20040204443A1 (en) * 2003-01-27 2004-10-14 Arthur Zaks Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
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PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
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FR2874611B1 (fr) * 2004-08-31 2006-11-17 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
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JP5433508B2 (ja) * 2009-06-25 2014-03-05 高田製薬株式会社 ゾルピデム酒石酸塩含有内用液剤
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JP7279067B2 (ja) * 2018-03-28 2023-05-22 武田薬品工業株式会社 複素環化合物及びその用途
EP3797097A4 (en) 2018-05-22 2022-03-09 President and Fellows of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
US11434244B2 (en) 2018-05-29 2022-09-06 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
EP3946390A4 (en) 2019-03-25 2022-12-21 President and Fellows of Harvard College COMPOSITIONS AND METHODS TO REDUCE TACTILE DYSFUNCTION, ANXIETY AND SOCIAL DISABILITIES
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途

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US3336194A (en) * 1963-04-30 1967-08-15 Merck & Co Inc Indolyl acid amides
GB1076089A (en) * 1965-11-09 1967-07-19 Selvi & C Lab Bioterapico New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

Also Published As

Publication number Publication date
NO155664B (no) 1987-01-26
IE812470L (en) 1982-04-22
DE3163524D1 (en) 1984-06-14
MX6463E (es) 1985-06-06
GR74701B (enExample) 1984-07-04
NZ198722A (en) 1984-10-19
NO155664C (no) 1987-05-06
CA1157470A (en) 1983-11-22
AU7668781A (en) 1983-04-28
DK465181A (da) 1982-04-23
DK154429C (da) 1989-04-17
ZA817297B (en) 1982-09-29
PT73863B (fr) 1983-11-07
JPS5798283A (en) 1982-06-18
PT73863A (fr) 1981-11-01
OA07076A (fr) 1984-01-31
NL930044I2 (nl) 1993-09-16
FI813288L (fi) 1982-04-23
FR2492382A1 (fr) 1982-04-23
ES506412A0 (es) 1982-09-16
US4460592A (en) 1984-07-17
NO813551L (no) 1982-04-23
LU88228I2 (enExample) 1994-02-03
FI71143C (fi) 1986-11-24
IE51686B1 (en) 1987-02-04
IL64091A0 (en) 1982-01-31
FI71143B (fi) 1986-08-14
EP0050563A1 (fr) 1982-04-28
IL64091A (en) 1984-12-31
JPS637545B2 (enExample) 1988-02-17
ATE7393T1 (de) 1984-05-15
FR2492382B1 (enExample) 1983-07-29
US4382938A (en) 1983-05-10
DK154429B (da) 1988-11-14
NL930044I1 (nl) 1993-08-02
ES8207537A1 (es) 1982-09-16
EP0050563B1 (fr) 1984-05-09

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