AU534007B2 - Polyol derivatives - Google Patents

Polyol derivatives

Info

Publication number
AU534007B2
AU534007B2 AU55872/80A AU5587280A AU534007B2 AU 534007 B2 AU534007 B2 AU 534007B2 AU 55872/80 A AU55872/80 A AU 55872/80A AU 5587280 A AU5587280 A AU 5587280A AU 534007 B2 AU534007 B2 AU 534007B2
Authority
AU
Australia
Prior art keywords
glyceryl
bis
acid
propylacetate
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU55872/80A
Other languages
English (en)
Other versions
AU5587280A (en
Inventor
Michel Chignac
Pierre Eymard
Bernard Ferrandes
Claude Grain
Fernand Jammot
Charles Pigerol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of AU5587280A publication Critical patent/AU5587280A/en
Application granted granted Critical
Publication of AU534007B2 publication Critical patent/AU534007B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU55872/80A 1979-03-06 1980-02-26 Polyol derivatives Ceased AU534007B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7907932 1979-03-06
GB7907932 1979-03-06

Publications (2)

Publication Number Publication Date
AU5587280A AU5587280A (en) 1980-09-11
AU534007B2 true AU534007B2 (en) 1983-12-22

Family

ID=10503667

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55872/80A Ceased AU534007B2 (en) 1979-03-06 1980-02-26 Polyol derivatives

Country Status (29)

Country Link
US (1) US4423071A (enExample)
EP (1) EP0018342B1 (enExample)
JP (1) JPS55141436A (enExample)
AR (1) AR224394A1 (enExample)
AU (1) AU534007B2 (enExample)
CA (1) CA1162928A (enExample)
CS (1) CS216526B2 (enExample)
CY (1) CY1209A (enExample)
DD (2) DD158773A5 (enExample)
DE (1) DE3061960D1 (enExample)
DK (1) DK93880A (enExample)
ES (1) ES8103015A1 (enExample)
FI (1) FI69449C (enExample)
GR (1) GR70703B (enExample)
HK (1) HK22384A (enExample)
HU (2) HU183072B (enExample)
IE (1) IE49539B1 (enExample)
IL (1) IL59407A (enExample)
IN (1) IN152492B (enExample)
MY (1) MY8500075A (enExample)
NO (1) NO152899C (enExample)
NZ (1) NZ192944A (enExample)
OA (1) OA06568A (enExample)
PL (1) PL124023B1 (enExample)
PT (1) PT70904A (enExample)
SG (1) SG61583G (enExample)
SU (3) SU1195901A3 (enExample)
YU (2) YU41699B (enExample)
ZA (1) ZA801081B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611561B2 (en) * 1988-05-26 1991-06-13 Masayoshi Nagayama Pharmaceutical composition for treating tumor

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US4654370A (en) * 1979-03-12 1987-03-31 Abbott Laboratories Glyceryl valproates
US5185159A (en) * 1983-07-20 1993-02-09 Sanofi Pharmaceutical composition based on valproic acid and a process for preparing it
IL72381A (en) * 1983-07-20 1988-03-31 Sanofi Sa Pharmaceutical composition based on valproic acid
US4590282A (en) * 1984-09-24 1986-05-20 Sandoz Ltd. Pest control agents
ES8705889A1 (es) * 1984-12-12 1987-06-01 Syntex Inc Un metodo para preparar eteres alcaximetilicos y esteres alcoximetilicos de derivados de guananina.
DK157308C (da) * 1985-02-27 1990-05-07 Novo Nordisk As Fremgangsmaade til fremstilling af acetal- eller ketalestere af polyoler eller monoestere af mono- eller disaccharider eller monoglycerider
US4591601A (en) * 1985-04-12 1986-05-27 Mcneilab, Inc. Anticonvulsant dioxolane methane sulfamates
IT1190133B (it) * 1986-06-19 1988-02-10 Chiesi Farma Spa Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche
FR2627487B1 (fr) * 1988-02-19 1991-03-29 Martin Laboratoires Nouveau derive de l'acide valproique, procede de preparation de ce compose ainsi que medicament antiepileptique le contenant
US5011977A (en) * 1988-04-08 1991-04-30 Eastman Kodak Company Transesterification of alkoxyesters
FR2641986B1 (fr) * 1989-01-26 1991-05-03 Oreal Procede de preparation de tensio-actifs non ioniques a partir de l'isopropylidene-1,2 epoxypropyl-3 glycerol et d'un acide carboxylique, nouveaux tensio-actifs non ioniques et leur utilisation
JPH02139136U (enExample) * 1989-04-24 1990-11-20
CA2060685A1 (en) * 1991-03-04 1992-09-05 Mahmood Sabahi Ether-ester lubricant
ES2158944T3 (es) * 1994-04-19 2001-09-16 Kanegafuchi Chemical Ind Procedimiento para producir un 2-aril-3-aciloxi-1,2-propanodiol opticamente activo.
CA2220091C (en) * 1995-05-01 2011-01-04 Scotia Holdings Plc Nicotinic acid esters and pharmaceutical compositions containing them
USRE40546E1 (en) * 1996-05-01 2008-10-21 Scarista, Ltd. 1,3-Propane diol esters and ethers and methods for their use in drug delivery
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
DE19534519A1 (de) * 1995-09-05 1997-07-10 Desitin Arzneimittel Gmbh Zucker oder Zuckeralkohole zur Verwendung als Antiepileptikum
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Pharmaceuticals, Inc. Delivery of drug esters through an inhalation route
JP4526741B2 (ja) * 2001-07-18 2010-08-18 花王株式会社 エーテルカルボキシレートモノグリセリド
FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
FR2850650B1 (fr) * 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
CA2526478A1 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
AU2004322756B2 (en) 2004-08-12 2011-04-14 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
ES2594867T3 (es) 2007-03-09 2016-12-23 Alexza Pharmaceuticals, Inc. Unidad de calentamiento para usar en un dispositivo de administración de fármaco
SE532942C2 (sv) * 2008-10-27 2010-05-18 Perstorp Specialty Chem Ab Smörjmedelsbasmassa med låg droppunkt
EP2354130A1 (en) * 2010-02-02 2011-08-10 Momentive Specialty Chemicals Research Belgium Manufacture of an epoxyethyl carboxylate or glycidyl carboxylate
US9493661B2 (en) 2011-11-17 2016-11-15 Basf Coatings Gmbh Glycerol diesters, method for producing same, and use of same in coatings materials
US9744542B2 (en) 2013-07-29 2017-08-29 Apeel Technology, Inc. Agricultural skin grafting
JP7157531B2 (ja) 2015-05-20 2022-10-20 アピール テクノロジー，インコーポレイテッド 植物抽出物組成物およびその調製方法
EP4793326A2 (en) 2015-09-16 2026-08-19 Apeel Technology, Inc. Method for forming a protective coating by applying fatty acid glyceride compounds to a surface
EP3386303B1 (en) 2015-12-10 2020-03-11 Apeel Technology, Inc. Process for depolymerising cutin
TWI731928B (zh) 2016-01-26 2021-07-01 美商ａＰＥＥＬ科技公司 製備及保存經消毒產品之方法
RU2761829C2 (ru) * 2016-06-07 2021-12-13 Зе Дж. Дэвид Глэдстоун Инститьютс Образуемые среднецепочечными жирными кислотами сложные эфиры бета-гидроксибутирата и бутандиола и композиции и способы на их основе
WO2018094269A1 (en) 2016-11-17 2018-05-24 Apeel Technology, Inc. Compositions formed from plant extracts and methods of preparation thereof
US12037317B2 (en) 2018-01-25 2024-07-16 Buck Institute For Research On Aging Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds
MX2020007997A (es) 2018-02-02 2020-12-03 Alexza Pharmaceuticals Inc Dispositivo electrico de aerosol de condensacion.
US12245605B2 (en) 2018-09-05 2025-03-11 Apeel Technology, Inc. Compounds and formulations for protective coatings
EP4114181A1 (en) 2020-03-04 2023-01-11 Apeel Technology, Inc. Coated agricultural products and corresponding methods
IL302360B2 (en) 2020-10-30 2025-01-01 Apeel Tech Inc Preparations and methods of their preparation
US12408680B2 (en) 2021-09-08 2025-09-09 Apeel Technology, Inc. Compounds and formulations for protective coatings

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US2010154A (en) * 1933-06-27 1935-08-06 Herbert S Kreighbaum Ether acid ester of polyhydric alcohols
US2348710A (en) * 1940-11-06 1944-05-16 American Cyanamid Co Alicyclic esters of alpha-hydroxyisobutyric acids
US2362326A (en) * 1940-11-06 1944-11-07 American Cyanamid Co Aromatic-glyceryl esters of alphahydroxyisobutyric acids
US2474796A (en) * 1946-01-31 1949-06-28 Wm S Merrell Co Alkylaminoalkyl esters of alicyclyl-alicyclic carboxylic acids
US2446505A (en) * 1946-04-12 1948-08-03 Doughnut Corp Method of inhibiting the growth of mold
US2627489A (en) * 1949-01-11 1953-02-03 Nathan L Drake Insect repellents
US2807638A (en) * 1953-05-01 1957-09-24 Shell Dev Polyhydric alcohol ester of a tertiary alkyl-substituted cyclohexanecarboxylic acid
US2962419A (en) * 1957-05-20 1960-11-29 Heyden Newport Chemical Corp Dietetic compositions
US2920056A (en) * 1957-06-06 1960-01-05 Exxon Research Engineering Co Plasticizer from polymethylol alkanes and 3-alkyl alkanoic acids and polymeric compositions containing same
US3178454A (en) * 1959-05-19 1965-04-13 Shell Oil Co Epoxy esters of alpha, alpha-dialkyl monocarboxylic acids
DE1289620B (de) * 1961-02-14 1969-02-20 Kolmar Laboratories Kosmetische, pharmazeutische oder schuetzende Mittel zur Aufbringung auf die Haut, sowie Salbengrundlagen
US3282971A (en) * 1963-06-19 1966-11-01 Exxon Research Engineering Co Fatty acid esters of polyhydric alcohols
GB1353381A (en) * 1971-02-04 1974-05-15 Wilkinson Sword Ltd Substituted p-menthanes and compositions containing them
CH557814A (de) * 1971-07-23 1975-01-15 Givaudan & Cie Sa Verfahren zur herstellung von neuen geschmackstoffen.
LU67263A1 (enExample) * 1973-03-22 1974-10-09
DE2713440A1 (de) * 1977-03-26 1978-09-28 Bayer Ag Carbonsaeureester, deren herstellung und verwendung als basisschmieroel
DE2728922C3 (de) * 1977-06-27 1982-02-25 Dragoco Gerberding & Co Gmbh, 3450 Holzminden Glycerintri-3,5,5-trimethylhexanoat
IL59407A (en) * 1979-03-06 1983-12-30 Sanofi Sa Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611561B2 (en) * 1988-05-26 1991-06-13 Masayoshi Nagayama Pharmaceutical composition for treating tumor

Also Published As

Publication number Publication date
PT70904A (en) 1980-04-01
IE800445L (en) 1980-09-06
FI69449B (fi) 1985-10-31
ZA801081B (en) 1981-03-25
EP0018342A1 (fr) 1980-10-29
AU5587280A (en) 1980-09-11
OA06568A (fr) 1981-08-31
ES489250A0 (es) 1981-02-16
JPS6315256B2 (enExample) 1988-04-04
YU292382A (en) 1983-09-30
FI69449C (fi) 1986-02-10
IE49539B1 (en) 1985-10-30
NZ192944A (en) 1984-07-06
IL59407A (en) 1983-12-30
SG61583G (en) 1985-02-15
HU183072B (en) 1984-04-28
CY1209A (en) 1983-12-31
IL59407A0 (en) 1980-05-30
NO152899B (no) 1985-09-02
ES8103015A1 (es) 1981-02-16
DK93880A (da) 1980-09-07
YU61580A (en) 1983-04-30
PL124023B1 (en) 1982-12-31
JPS55141436A (en) 1980-11-05
HU188840B (en) 1986-05-28
EP0018342B1 (fr) 1983-02-16
YU42064B (en) 1988-04-30
IN152492B (enExample) 1984-01-28
AR224394A1 (es) 1981-11-30
DE3061960D1 (en) 1983-03-24
CS216526B2 (en) 1982-11-26
GR70703B (enExample) 1983-01-04
DD151931A5 (de) 1981-11-11
SU1225481A3 (ru) 1986-04-15
NO152899C (no) 1985-12-11
HK22384A (en) 1984-03-23
PL222446A1 (enExample) 1981-01-30
NO800626L (no) 1980-09-08
SU1195901A3 (ru) 1985-11-30
FI800683A7 (fi) 1980-09-07
SU1052507A1 (ru) 1983-11-07
YU41699B (en) 1987-12-31
DD158773A5 (de) 1983-02-02
US4423071A (en) 1983-12-27
MY8500075A (en) 1985-12-31
CA1162928A (en) 1984-02-28

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