AU4600200A - Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof - Google Patents

Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Info

Publication number
AU4600200A
AU4600200A AU46002/00A AU4600200A AU4600200A AU 4600200 A AU4600200 A AU 4600200A AU 46002/00 A AU46002/00 A AU 46002/00A AU 4600200 A AU4600200 A AU 4600200A AU 4600200 A AU4600200 A AU 4600200A
Authority
AU
Australia
Prior art keywords
dimethyl
salts
preparation
intermediates
dioxane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46002/00A
Other languages
English (en)
Inventor
Laszlo Balazs
Jozsef Barkoczy
Ferenc Bartha
Imre Doman
Zoltan Greff
Peter Kotay Nagy
Kalman Nagy
Zoltan Ratkai
Peter Seres
Gyula Simig
Gyorgyi Vereczkeyne Donath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of AU4600200A publication Critical patent/AU4600200A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AU46002/00A 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof Abandoned AU4600200A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9901526A HU227840B1 (en) 1999-05-06 1999-05-06 Intermediates of atorvastatin synthesis and process for producing them
HU901526 1999-05-06
PCT/HU2000/000042 WO2000068221A1 (en) 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Publications (1)

Publication Number Publication Date
AU4600200A true AU4600200A (en) 2000-11-21

Family

ID=89998261

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46002/00A Abandoned AU4600200A (en) 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Country Status (14)

Country Link
EP (1) EP1178980A1 (zh)
JP (1) JP2002544207A (zh)
KR (1) KR20020033617A (zh)
CN (1) CN1349522A (zh)
AU (1) AU4600200A (zh)
CA (1) CA2373077A1 (zh)
CZ (1) CZ20013965A3 (zh)
HK (1) HK1046271A1 (zh)
HR (1) HRP20010846A2 (zh)
HU (1) HU227840B1 (zh)
PL (1) PL351145A1 (zh)
RU (1) RU2001133066A (zh)
SK (1) SK15842001A3 (zh)
WO (1) WO2000068221A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
WO2002057229A1 (en) * 2001-01-19 2002-07-25 Biocon India Limited FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN)
US7199261B2 (en) 2001-07-06 2007-04-03 Teva Pharmaceutical Industries Ltd Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
CA2601111A1 (en) 2005-03-14 2006-09-21 Pfizer Science And Technology Ireland Limited Preparation of an atorvastatin intermediate using a paal-knorr condensation
WO2007034909A1 (ja) * 2005-09-22 2007-03-29 Kaneka Corporation （３ｒ，５ｒ）－７－アミノ－３，５－ジヒドロキシヘプタン酸誘導体の製造法
CN103153976B (zh) * 2010-09-09 2015-07-08 中化帝斯曼制药有限公司荷兰公司 7-氨基-3,5-二羟基庚酸酯的盐
CN113620871A (zh) 2015-08-05 2021-11-09 株式会社Api 生产匹伐他汀钙的方法
CN108191813B (zh) * 2017-12-20 2020-01-17 帕潘纳(北京)科技有限公司 一种缩酮的制备方法
CN109232354A (zh) * 2018-10-09 2019-01-18 河南师范大学 一种高纯度阿托伐他汀钙原料药的制备方法
CN109232353A (zh) * 2018-10-09 2019-01-18 河南师范大学 一种阿托伐他汀钙缩合物的制备方法
CN110940764B (zh) * 2019-12-31 2022-06-28 湖南九典制药股份有限公司 一种他汀类药物光学异构体的分离方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5103024A (en) * 1990-10-17 1992-04-07 Warner-Lambert Company Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US5155251A (en) * 1991-10-11 1992-10-13 Warner-Lambert Company Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5278313A (en) * 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
JP3652394B2 (ja) * 1995-01-27 2005-05-25 高砂香料工業株式会社 Ｎ−置換−７−アミノ−５−ヒドロキシ−３−オキソヘプタン酸誘導体およびその製造法
TR199900191T2 (xx) * 1996-07-29 1999-04-21 Warner-Lambert Company (S)-3,4-Dihidroksibutirik asitin korumal� esterlerinin sentezi i�in geli�tirilmi� proses.
EP1077212B1 (en) * 1998-04-30 2003-08-20 Kaneka Corporation Process for producing 6-cyanomethyl-1,3-dioxane-4-acetic acid derivatives

Also Published As

Publication number Publication date
CN1349522A (zh) 2002-05-15
CA2373077A1 (en) 2000-11-16
KR20020033617A (ko) 2002-05-07
JP2002544207A (ja) 2002-12-24
PL351145A1 (en) 2003-03-24
HU227840B1 (en) 2012-05-02
CZ20013965A3 (cs) 2002-04-17
EP1178980A1 (en) 2002-02-13
SK15842001A3 (sk) 2002-04-04
RU2001133066A (ru) 2004-02-27
HRP20010846A2 (en) 2003-02-28
HK1046271A1 (zh) 2003-01-03
HU9901526D0 (en) 1999-07-28
HUP9901526A2 (hu) 2001-04-28
WO2000068221A1 (en) 2000-11-16

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
TH Corrigenda

Free format text: IN VOL 15, NO 9, PAGE(S) 1641-1644 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 32736/00, 39341/00, 41415/00, 41417/00, 41418/00, 43916/00, 46002/00 AND 72243/00

MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase