AU2020232757B2 - JAK1 pathway inhibitors for the treatment of chronic lung allograft dysfunction - Google Patents

JAK1 pathway inhibitors for the treatment of chronic lung allograft dysfunction

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Publication number
AU2020232757B2
AU2020232757B2 AU2020232757A AU2020232757A AU2020232757B2 AU 2020232757 B2 AU2020232757 B2 AU 2020232757B2 AU 2020232757 A AU2020232757 A AU 2020232757A AU 2020232757 A AU2020232757 A AU 2020232757A AU 2020232757 B2 AU2020232757 B2 AU 2020232757B2
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AU
Australia
Prior art keywords
subject
pharmaceutically acceptable
acceptable salt
pathway inhibitor
jak1 pathway
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AU2020232757A
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English (en)
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AU2020232757A1 (en
Inventor
Kevin O'HAYER
Richard L. SCHAUB
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Incyte Corp
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Incyte Corp
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Publication of AU2020232757A1 publication Critical patent/AU2020232757A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2020232757A 2019-03-05 2020-03-05 JAK1 pathway inhibitors for the treatment of chronic lung allograft dysfunction Active AU2020232757B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962814085P 2019-03-05 2019-03-05
US62/814,085 2019-03-05
PCT/US2020/021088 WO2020181034A1 (en) 2019-03-05 2020-03-05 Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction

Publications (2)

Publication Number Publication Date
AU2020232757A1 AU2020232757A1 (en) 2021-10-07
AU2020232757B2 true AU2020232757B2 (en) 2025-09-11

Family

ID=69941525

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020232757A Active AU2020232757B2 (en) 2019-03-05 2020-03-05 JAK1 pathway inhibitors for the treatment of chronic lung allograft dysfunction

Country Status (15)

Country Link
US (2) US11406640B2 (https=)
EP (2) EP3934651A1 (https=)
JP (2) JP2022524997A (https=)
KR (1) KR20210137087A (https=)
CN (1) CN114007621A (https=)
AU (1) AU2020232757B2 (https=)
CA (1) CA3132371A1 (https=)
EA (1) EA202192426A1 (https=)
IL (1) IL285999B2 (https=)
MA (1) MA55201A (https=)
MX (2) MX2021010545A (https=)
PH (1) PH12021552130A1 (https=)
SG (1) SG11202109563WA (https=)
UA (1) UA130579C2 (https=)
WO (1) WO2020181034A1 (https=)

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Also Published As

Publication number Publication date
AU2020232757A1 (en) 2021-10-07
EP4691567A3 (en) 2026-04-29
WO2020181034A1 (en) 2020-09-10
JP2022524997A (ja) 2022-05-11
CN114007621A (zh) 2022-02-01
MX2024007081A (es) 2024-06-21
MA55201A (fr) 2022-01-12
SG11202109563WA (en) 2021-09-29
EP3934651A1 (en) 2022-01-12
IL285999B1 (en) 2025-09-01
CA3132371A1 (en) 2020-09-10
PH12021552130A1 (en) 2022-08-31
KR20210137087A (ko) 2021-11-17
EP4691567A2 (en) 2026-02-11
UA130579C2 (uk) 2026-03-25
IL285999B2 (en) 2026-01-01
US20220331325A1 (en) 2022-10-20
MX2021010545A (es) 2021-11-17
IL285999A (en) 2021-10-31
US11406640B2 (en) 2022-08-09
JP2025087734A (ja) 2025-06-10
US20200281931A1 (en) 2020-09-10
EA202192426A1 (ru) 2021-11-15
US11896595B2 (en) 2024-02-13

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