CA3132371A1 - Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction - Google Patents

Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction Download PDF

Info

Publication number
CA3132371A1
CA3132371A1 CA3132371A CA3132371A CA3132371A1 CA 3132371 A1 CA3132371 A1 CA 3132371A1 CA 3132371 A CA3132371 A CA 3132371A CA 3132371 A CA3132371 A CA 3132371A CA 3132371 A1 CA3132371 A1 CA 3132371A1
Authority
CA
Canada
Prior art keywords
pharmaceutically acceptable
acceptable salt
jak1
subject
pathway inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3132371A
Other languages
English (en)
French (fr)
Inventor
Richard L. SCHAUB
Kevin O'HAYER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of CA3132371A1 publication Critical patent/CA3132371A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3132371A 2019-03-05 2020-03-05 Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction Pending CA3132371A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962814085P 2019-03-05 2019-03-05
US62/814,085 2019-03-05
PCT/US2020/021088 WO2020181034A1 (en) 2019-03-05 2020-03-05 Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction

Publications (1)

Publication Number Publication Date
CA3132371A1 true CA3132371A1 (en) 2020-09-10

Family

ID=69941525

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3132371A Pending CA3132371A1 (en) 2019-03-05 2020-03-05 Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction

Country Status (15)

Country Link
US (2) US11406640B2 (https=)
EP (2) EP4691567A3 (https=)
JP (2) JP2022524997A (https=)
KR (1) KR20210137087A (https=)
CN (1) CN114007621A (https=)
AU (1) AU2020232757B2 (https=)
CA (1) CA3132371A1 (https=)
EA (1) EA202192426A1 (https=)
IL (1) IL285999B2 (https=)
MA (1) MA55201A (https=)
MX (2) MX2021010545A (https=)
PH (1) PH12021552130A1 (https=)
SG (1) SG11202109563WA (https=)
UA (1) UA130579C2 (https=)
WO (1) WO2020181034A1 (https=)

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Also Published As

Publication number Publication date
EP3934651A1 (en) 2022-01-12
US11406640B2 (en) 2022-08-09
AU2020232757A1 (en) 2021-10-07
IL285999B1 (en) 2025-09-01
UA130579C2 (uk) 2026-03-25
WO2020181034A1 (en) 2020-09-10
JP2025087734A (ja) 2025-06-10
EP4691567A3 (en) 2026-04-29
KR20210137087A (ko) 2021-11-17
PH12021552130A1 (en) 2022-08-31
CN114007621A (zh) 2022-02-01
EP4691567A2 (en) 2026-02-11
US20200281931A1 (en) 2020-09-10
EA202192426A1 (ru) 2021-11-15
IL285999A (en) 2021-10-31
AU2020232757B2 (en) 2025-09-11
JP2022524997A (ja) 2022-05-11
IL285999B2 (en) 2026-01-01
US20220331325A1 (en) 2022-10-20
MX2024007081A (es) 2024-06-21
SG11202109563WA (en) 2021-09-29
MX2021010545A (es) 2021-11-17
US11896595B2 (en) 2024-02-13
MA55201A (fr) 2022-01-12

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