AU2018276434B2 - Long-acting GIP peptide analogues - Google Patents
Long-acting GIP peptide analogues Download PDFInfo
- Publication number
- AU2018276434B2 AU2018276434B2 AU2018276434A AU2018276434A AU2018276434B2 AU 2018276434 B2 AU2018276434 B2 AU 2018276434B2 AU 2018276434 A AU2018276434 A AU 2018276434A AU 2018276434 A AU2018276434 A AU 2018276434A AU 2018276434 B2 AU2018276434 B2 AU 2018276434B2
- Authority
- AU
- Australia
- Prior art keywords
- seq
- hgip
- amino acid
- gip
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17173628 | 2017-05-31 | ||
| EP17173628.3 | 2017-05-31 | ||
| PCT/EP2018/064355 WO2018220123A1 (en) | 2017-05-31 | 2018-05-31 | Long-acting gip peptide analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2018276434A1 AU2018276434A1 (en) | 2020-01-02 |
| AU2018276434B2 true AU2018276434B2 (en) | 2021-12-16 |
Family
ID=59021262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018276434A Active AU2018276434B2 (en) | 2017-05-31 | 2018-05-31 | Long-acting GIP peptide analogues |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11572399B2 (enExample) |
| EP (2) | EP3630806B1 (enExample) |
| JP (1) | JP2020521784A (enExample) |
| KR (1) | KR102743887B1 (enExample) |
| CN (1) | CN110691788B (enExample) |
| AU (1) | AU2018276434B2 (enExample) |
| BR (1) | BR112019025195A8 (enExample) |
| ES (1) | ES2972848T3 (enExample) |
| PL (1) | PL3630806T3 (enExample) |
| WO (1) | WO2018220123A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3189072B1 (en) | 2014-09-05 | 2018-07-18 | University of Copenhagen | Gip peptide analogues |
| BR112019025195A8 (pt) | 2017-05-31 | 2020-07-07 | Univ Copenhagen | análogos do peptídeo gip de ação prolongada |
| TWI707865B (zh) * | 2018-05-04 | 2020-10-21 | 丹麥商諾佛 儂迪克股份有限公司 | Gip衍生物及其用途 |
| US12297250B2 (en) * | 2018-12-03 | 2025-05-13 | Antag Therapeutics Aps | Modified GIP peptide analogues |
| JP7788376B2 (ja) * | 2019-12-03 | 2025-12-18 | アンタグ セラピューティクス エーピーエス | 最適化されたgipペプチド類縁体 |
| WO2023139106A2 (en) | 2022-01-18 | 2023-07-27 | Novo Nordisk A/S | Long-acting gipr antagonists |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012088379A2 (en) * | 2010-12-22 | 2012-06-28 | Marcadia Biotech, Inc. | Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| AU5518798A (en) | 1996-12-03 | 1998-06-29 | Trustees Of Boston University | Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) |
| JP3270761B2 (ja) | 1998-01-30 | 2002-04-02 | ノボ ノルディスク アクティーゼルスカブ | 注射器 |
| AU3247799A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
| ATE269103T1 (de) | 1998-03-13 | 2004-07-15 | Novo Nordisk As | Stabilisierte wässerige glukagonlösungen enthaltend detergenzien |
| AU6294899A (en) | 1998-10-07 | 2000-04-26 | Medical College Of Georgia Research Institute, Inc. | Glucose-dependent insulinotropic peptide for use as an osteotropic hormone |
| CN1495198A (zh) | 1998-12-07 | 2004-05-12 | �о���Ӧ�ÿ�ѧЭ��ɷ�����˾ | 胰高血糖素样肽-1的类似物 |
| US20050272652A1 (en) | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| GB0404124D0 (en) * | 2004-02-25 | 2004-03-31 | Univ Ulster | Antagonists of GIP |
| US6921748B1 (en) | 1999-03-29 | 2005-07-26 | Uutech Limited | Analogs of gastric inhibitory polypeptide and their use for treatment of diabetes |
| UA93662C2 (uk) | 2000-12-07 | 2011-03-10 | Эли Лилли Энд Компани | Гетерологічний пептидильований глюкагон-подібний білок та його застосування для виготовлення лікарського засобу для лікування пацієнтів, що страждають на ожиріння або інсулінонезалежний цукровий діабет |
| US20030232761A1 (en) | 2002-03-28 | 2003-12-18 | Hinke Simon A. | Novel analogues of glucose-dependent insulinotropic polypeptide |
| WO2004067548A2 (en) | 2003-01-31 | 2004-08-12 | Theratechnologies Inc. | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
| US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
| EP1853627A2 (en) | 2005-02-11 | 2007-11-14 | Amylin Pharmaceuticals, Inc. | Gip analog and hybrid polypeptides with selectable properties |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| CN101432025B (zh) | 2006-03-21 | 2012-04-04 | 安米林药品公司 | 肽-肽酶抑制剂结合物及其使用方法 |
| WO2008021560A2 (en) * | 2006-08-17 | 2008-02-21 | Amylin Pharmaceuticals, Inc. | Dpp-iv resistant gip hybrid polypeptides with selectable properties |
| WO2010016936A1 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide |
| BRPI0917580A2 (pt) | 2008-08-07 | 2016-10-11 | Ipsen Pharma Sas | composto, composição farmacêutica, métodos para elicitar um efeito agonista e antagonista de um receptor de gip, para tratar condições ou doenças mediadas por ligação de receptor de gip, para tratar diabetes, para tratar distúrbios relacionados com diabete, para tratar ou previnir causas secundárias de diabete para tratar obesidade, e para estimular secreção de insulina, e, uso de um análogo de peptídeo |
| CA2733005C (en) | 2008-08-07 | 2016-09-27 | Ipsen Pharma S.A.S. | Truncated analogues of glucose-dependent insulinotropic polypeptide |
| EP2328922A4 (en) | 2008-08-07 | 2013-01-02 | Ipsen Pharma Sas | ANALOGUE OF GLUCOSE-DEPENDING INSULINOTROPIC POLYPEPTIDE |
| KR20130133104A (ko) | 2008-08-07 | 2013-12-05 | 입센 파마 에스.에이.에스 | 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드 유사체 |
| RU2012136450A (ru) * | 2010-01-27 | 2014-03-10 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Конъюгаты антагонист глюкагона - агонист gip и композиции для лечения метаболических расстройств и ожирения |
| US9023986B2 (en) | 2010-10-25 | 2015-05-05 | Hoffmann-La Roche Inc. | Glucose-dependent insulinotropic peptide analogs |
| WO2012167744A1 (en) * | 2011-06-10 | 2012-12-13 | Beijing Hanmi Pharmaceutical Co., Ltd. | Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof |
| US20140377171A1 (en) * | 2011-06-10 | 2014-12-25 | Jean Claude Reubi | Imaging and Treatment of Neuroendocrine Tumors with Glucose - Dependent Insulinotropic Polypeptide or Analogues or Antagonists Thereof |
| EP2986314A4 (en) | 2013-03-15 | 2016-04-13 | Univ Indiana Res & Tech Corp | PRODRUGS WITH EXTENDED EFFECT |
| EP3189072B1 (en) * | 2014-09-05 | 2018-07-18 | University of Copenhagen | Gip peptide analogues |
| TWI705973B (zh) * | 2014-10-29 | 2020-10-01 | 丹麥商西蘭製藥公司 | Gip促效劑化合物及方法 |
| WO2016205488A1 (en) | 2015-06-17 | 2016-12-22 | The California Institute For Biomedical Research | Modified therapeutic agents and compositions thereof |
| US10774127B2 (en) * | 2016-10-12 | 2020-09-15 | University Of Copenhagen | Peptide dual agonists of GIPR and GLP2R |
| EP3569248B1 (en) | 2016-12-26 | 2023-12-06 | Kao Corporation | Gip inhibitors for improving cognitive function |
| EP3560514A4 (en) | 2016-12-26 | 2020-12-23 | Kao Corporation | Hypothermic drugs |
| WO2018124011A1 (ja) | 2016-12-26 | 2018-07-05 | 花王株式会社 | 運動調節機能向上剤 |
| BR112019025195A8 (pt) | 2017-05-31 | 2020-07-07 | Univ Copenhagen | análogos do peptídeo gip de ação prolongada |
-
2018
- 2018-05-31 BR BR112019025195A patent/BR112019025195A8/pt unknown
- 2018-05-31 EP EP18728872.5A patent/EP3630806B1/en active Active
- 2018-05-31 CN CN201880036341.0A patent/CN110691788B/zh active Active
- 2018-05-31 PL PL18728872.5T patent/PL3630806T3/pl unknown
- 2018-05-31 JP JP2019565921A patent/JP2020521784A/ja active Pending
- 2018-05-31 US US16/617,698 patent/US11572399B2/en active Active
- 2018-05-31 AU AU2018276434A patent/AU2018276434B2/en active Active
- 2018-05-31 ES ES18728872T patent/ES2972848T3/es active Active
- 2018-05-31 EP EP24150677.3A patent/EP4361173A3/en active Pending
- 2018-05-31 KR KR1020197034279A patent/KR102743887B1/ko active Active
- 2018-05-31 WO PCT/EP2018/064355 patent/WO2018220123A1/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012088379A2 (en) * | 2010-12-22 | 2012-06-28 | Marcadia Biotech, Inc. | Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides |
Non-Patent Citations (1)
| Title |
|---|
| PATHAK V ET AL, MOLECULAR AND CELLULAR ENDOCRINOLOGY, (2014-11-06), vol. 401, doi:10.1016/J.MCE.2014.10.025, ISSN 0303-7207, pages 120 - 129 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA3064510A1 (en) | 2018-12-06 |
| CN110691788A (zh) | 2020-01-14 |
| KR20200014287A (ko) | 2020-02-10 |
| US20200087373A1 (en) | 2020-03-19 |
| KR102743887B1 (ko) | 2024-12-19 |
| EP3630806A1 (en) | 2020-04-08 |
| EP4361173A3 (en) | 2024-07-03 |
| CN110691788B (zh) | 2024-05-31 |
| AU2018276434A1 (en) | 2020-01-02 |
| BR112019025195A2 (pt) | 2020-06-23 |
| BR112019025195A8 (pt) | 2020-07-07 |
| US11572399B2 (en) | 2023-02-07 |
| EP4361173A2 (en) | 2024-05-01 |
| WO2018220123A1 (en) | 2018-12-06 |
| EP3630806B1 (en) | 2024-01-10 |
| PL3630806T3 (pl) | 2024-05-13 |
| ES2972848T3 (es) | 2024-06-17 |
| JP2020521784A (ja) | 2020-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |