JP2020521784A - 長時間作用性ｇｉｐペプチド類似体 - Google Patents

長時間作用性ｇｉｐペプチド類似体 Download PDF

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JP2020521784A
JP2020521784A JP2019565921A JP2019565921A JP2020521784A JP 2020521784 A JP2020521784 A JP 2020521784A JP 2019565921 A JP2019565921 A JP 2019565921A JP 2019565921 A JP2019565921 A JP 2019565921A JP 2020521784 A JP2020521784 A JP 2020521784A
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seq
amino acid
fatty acid
gip
acid molecule
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JP2020521784A5 (enExample
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ローセンキレ，メッテ，マリー
ホルスト，イェンス，ユール
ガスビャーグ，レアケ，スミド
シュパラー−ウルリヒ，アレクサンドル，ホヴァード
ゲイブ，マリア，バー，ノルドスコヴ
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ユニバーシティ オブ コペンハーゲン
ユニバーシティ オブ コペンハーゲン
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Publication of JP2020521784A publication Critical patent/JP2020521784A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
JP2019565921A 2017-05-31 2018-05-31 長時間作用性ｇｉｐペプチド類似体 Pending JP2020521784A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173628.3 2017-05-31
EP17173628 2017-05-31
PCT/EP2018/064355 WO2018220123A1 (en) 2017-05-31 2018-05-31 Long-acting gip peptide analogues

Publications (2)

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JP2020521784A true JP2020521784A (ja) 2020-07-27
JP2020521784A5 JP2020521784A5 (enExample) 2021-07-26

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JP2019565921A Pending JP2020521784A (ja) 2017-05-31 2018-05-31 長時間作用性ｇｉｐペプチド類似体

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US (1) US11572399B2 (enExample)
EP (2) EP3630806B1 (enExample)
JP (1) JP2020521784A (enExample)
KR (1) KR102743887B1 (enExample)
CN (1) CN110691788B (enExample)
AU (1) AU2018276434B2 (enExample)
BR (1) BR112019025195A8 (enExample)
ES (1) ES2972848T3 (enExample)
PL (1) PL3630806T3 (enExample)
WO (1) WO2018220123A1 (enExample)

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* Cited by examiner, † Cited by third party
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WO2016034186A1 (en) 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
US11572399B2 (en) 2017-05-31 2023-02-07 University Of Copenhagen Long-acting GIP peptide analogues
PE20210473A1 (es) * 2018-05-04 2021-03-08 Novo Nordisk As Derivados de gip y usos de estos
US12187773B2 (en) * 2018-12-03 2025-01-07 Antag Therapeutics Aps Modified GIP peptide analogues
CN122520749A (zh) * 2019-12-03 2026-08-07 安泰博医药 优化的gip肽类似物
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists

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JP2010500996A (ja) * 2006-08-17 2010-01-14 アミリン・ファーマシューティカルズ，インコーポレイテッド 選択可能な特性を持つｄｐｐ−ｉｖ耐性ｇｉｐハイブリッドポリペプチド
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WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods
JP2016521253A (ja) * 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ

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US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
AU5518798A (en) 1996-12-03 1998-06-29 Trustees Of Boston University Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)
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DE69918070T2 (de) 1998-03-13 2005-08-25 Novo Nordisk A/S Stabilisierte, wässrige Glukagonlösungen, enthaltend Detergenzien
DE69926007T2 (de) 1998-10-07 2005-12-29 Medical College Of Georgia Research Institute, Inc. Glukose-abhängiges, insulinotropisches peptid für die verwendung als osteotropes hormon
EP1137667B1 (en) 1998-12-07 2004-11-17 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Analogues of glp-1
ATE272650T1 (de) 1999-03-29 2004-08-15 Uutech Ltd Analoge des magensaft inhibierenden peptides und ihre verwendung für die behandlung von diabetes
SI1724284T1 (sl) 2000-12-07 2009-12-31 Lilly Co Eli Glp-1 fuzijski proteini
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RU2013133803A (ru) * 2010-12-22 2015-01-27 Маркадиа Байотек, Инк. Способы лечения метаболических нарушений и ожирения при помощи пептидов на основе глюкагона, активных по отношению к рецепторам гип и гпп
US20140377171A1 (en) * 2011-06-10 2014-12-25 Jean Claude Reubi Imaging and Treatment of Neuroendocrine Tumors with Glucose - Dependent Insulinotropic Polypeptide or Analogues or Antagonists Thereof
KR102002783B1 (ko) * 2011-06-10 2019-07-24 베이징 한미 파마슈티컬 컴퍼니 리미티드 포도당 의존성 인슐리노트로핀 폴리펩타이드 유사물질, 이의 약학적 조성물 및 응용
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* Cited by examiner, † Cited by third party
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US20080009603A1 (en) * 1999-03-29 2008-01-10 Uutech Limited Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
JP2008500280A (ja) * 2004-02-25 2008-01-10 ユニバーシティ オブ アルスター 糖尿病、インスリン抵抗性、及び肥満症の治療のためのｇｉｐペプチド・アナログ
JP2010500996A (ja) * 2006-08-17 2010-01-14 アミリン・ファーマシューティカルズ，インコーポレイテッド 選択可能な特性を持つｄｐｐ−ｉｖ耐性ｇｉｐハイブリッドポリペプチド
JP2013518115A (ja) * 2010-01-27 2013-05-20 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐ｇｉｐアゴニスト複合体及び組成物
JP2016521253A (ja) * 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ
WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

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ES2972848T3 (es) 2024-06-17
AU2018276434A1 (en) 2020-01-02
BR112019025195A8 (pt) 2020-07-07
EP4361173A2 (en) 2024-05-01
EP3630806A1 (en) 2020-04-08
AU2018276434B2 (en) 2021-12-16
CN110691788B (zh) 2024-05-31
EP3630806B1 (en) 2024-01-10
CN110691788A (zh) 2020-01-14
KR102743887B1 (ko) 2024-12-19
PL3630806T3 (pl) 2024-05-13
EP4361173A3 (en) 2024-07-03
BR112019025195A2 (pt) 2020-06-23
WO2018220123A1 (en) 2018-12-06
CA3064510A1 (en) 2018-12-06
US11572399B2 (en) 2023-02-07
US20200087373A1 (en) 2020-03-19
KR20200014287A (ko) 2020-02-10

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