JP2020521784A - 長時間作用性ｇｉｐペプチド類似体 - Google Patents

長時間作用性ｇｉｐペプチド類似体 Download PDF

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JP2020521784A
JP2020521784A JP2019565921A JP2019565921A JP2020521784A JP 2020521784 A JP2020521784 A JP 2020521784A JP 2019565921 A JP2019565921 A JP 2019565921A JP 2019565921 A JP2019565921 A JP 2019565921A JP 2020521784 A JP2020521784 A JP 2020521784A
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seq
amino acid
fatty acid
gip
acid molecule
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JP2020521784A5 (enExample
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ローセンキレ，メッテ，マリー
ホルスト，イェンス，ユール
ガスビャーグ，レアケ，スミド
シュパラー−ウルリヒ，アレクサンドル，ホヴァード
ゲイブ，マリア，バー，ノルドスコヴ
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ユニバーシティ オブ コペンハーゲン
ユニバーシティ オブ コペンハーゲン
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Publication of JP2020521784A publication Critical patent/JP2020521784A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
JP2019565921A 2017-05-31 2018-05-31 長時間作用性ｇｉｐペプチド類似体 Pending JP2020521784A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173628.3 2017-05-31
EP17173628 2017-05-31
PCT/EP2018/064355 WO2018220123A1 (en) 2017-05-31 2018-05-31 Long-acting gip peptide analogues

Publications (2)

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JP2020521784A true JP2020521784A (ja) 2020-07-27
JP2020521784A5 JP2020521784A5 (enExample) 2021-07-26

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JP2019565921A Pending JP2020521784A (ja) 2017-05-31 2018-05-31 長時間作用性ｇｉｐペプチド類似体

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US (1) US11572399B2 (enExample)
EP (2) EP3630806B1 (enExample)
JP (1) JP2020521784A (enExample)
KR (1) KR102743887B1 (enExample)
CN (1) CN110691788B (enExample)
AU (1) AU2018276434B2 (enExample)
BR (1) BR112019025195A8 (enExample)
CA (1) CA3064510A1 (enExample)
ES (1) ES2972848T3 (enExample)
PL (1) PL3630806T3 (enExample)
WO (1) WO2018220123A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10968266B2 (en) 2014-09-05 2021-04-06 University Of Copenhagen GIP peptide analogues
CN110691788B (zh) 2017-05-31 2024-05-31 哥本哈根大学 长效gip肽类似物
CN112074531B (zh) * 2018-05-04 2025-04-15 诺和诺德股份有限公司 Gip衍生物及其用途
KR20210102911A (ko) 2018-12-03 2021-08-20 안타그 테라퓨틱스 에이피에스 변형된 gip 펩티드 유사체
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists

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US20080009603A1 (en) * 1999-03-29 2008-01-10 Uutech Limited Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
JP2010500996A (ja) * 2006-08-17 2010-01-14 アミリン・ファーマシューティカルズ，インコーポレイテッド 選択可能な特性を持つｄｐｐ−ｉｖ耐性ｇｉｐハイブリッドポリペプチド
JP2013518115A (ja) * 2010-01-27 2013-05-20 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐ｇｉｐアゴニスト複合体及び組成物
WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods
JP2016521253A (ja) * 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ

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ES2283025T3 (es) 1996-08-30 2007-10-16 Novo Nordisk A/S Derivados de glp-1.1.
US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6384016B1 (en) 1998-03-13 2002-05-07 Novo Nordisk A/S Stabilized aqueous peptide solutions
AU5518798A (en) 1996-12-03 1998-06-29 Trustees Of Boston University Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)
UA56256C2 (uk) 1998-01-30 2003-05-15 Ново Нордіск А/С Шприц для ін'єкцій
WO1999043708A1 (en) 1998-02-27 1999-09-02 Novo Nordisk A/S Glp-1 derivatives of glp-1 and exendin with protracted profile of action
AU6294899A (en) 1998-10-07 2000-04-26 Medical College Of Georgia Research Institute, Inc. Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
SG125915A1 (en) 1998-12-07 2006-10-30 Sod Conseils Rech Applic Analogues of glp-1
PT1171465E (pt) 1999-03-29 2004-12-31 Uutech Ltd Analogos de petido inibidor gastrico e sua utilizacao para o tratamento de diabetes
DK1355942T3 (da) 2000-12-07 2008-11-17 Lilly Co Eli GLP-1-fusionsproteiner
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AR084558A1 (es) * 2010-12-22 2013-05-22 Marcadia Biotech Metodos para tratar trastornos metabolicos y obesidad con peptidos basados en glucagon activos para el receptor de peptido insulinotropico dependiente de glucosa (gip)/peptido-1 similar al glucagon (glp-1)
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CN110691788B (zh) 2017-05-31 2024-05-31 哥本哈根大学 长效gip肽类似物

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* Cited by examiner, † Cited by third party
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US20080009603A1 (en) * 1999-03-29 2008-01-10 Uutech Limited Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
JP2008500280A (ja) * 2004-02-25 2008-01-10 ユニバーシティ オブ アルスター 糖尿病、インスリン抵抗性、及び肥満症の治療のためのｇｉｐペプチド・アナログ
JP2010500996A (ja) * 2006-08-17 2010-01-14 アミリン・ファーマシューティカルズ，インコーポレイテッド 選択可能な特性を持つｄｐｐ−ｉｖ耐性ｇｉｐハイブリッドポリペプチド
JP2013518115A (ja) * 2010-01-27 2013-05-20 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐ｇｉｐアゴニスト複合体及び組成物
JP2016521253A (ja) * 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ
WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

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ES2972848T3 (es) 2024-06-17
CA3064510A1 (en) 2018-12-06
AU2018276434B2 (en) 2021-12-16
US20200087373A1 (en) 2020-03-19
CN110691788B (zh) 2024-05-31
PL3630806T3 (pl) 2024-05-13
BR112019025195A8 (pt) 2020-07-07
BR112019025195A2 (pt) 2020-06-23
CN110691788A (zh) 2020-01-14
EP3630806B1 (en) 2024-01-10
EP3630806A1 (en) 2020-04-08
AU2018276434A1 (en) 2020-01-02
US11572399B2 (en) 2023-02-07
KR102743887B1 (ko) 2024-12-19
WO2018220123A1 (en) 2018-12-06
EP4361173A3 (en) 2024-07-03
EP4361173A2 (en) 2024-05-01
KR20200014287A (ko) 2020-02-10

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