JP2020521784A - 長時間作用性ｇｉｐペプチド類似体 - Google Patents

長時間作用性ｇｉｐペプチド類似体 Download PDF

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JP2020521784A
JP2020521784A JP2019565921A JP2019565921A JP2020521784A JP 2020521784 A JP2020521784 A JP 2020521784A JP 2019565921 A JP2019565921 A JP 2019565921A JP 2019565921 A JP2019565921 A JP 2019565921A JP 2020521784 A JP2020521784 A JP 2020521784A
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seq
amino acid
fatty acid
gip
acid molecule
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JP2020521784A5 (enExample
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ローセンキレ，メッテ，マリー
ホルスト，イェンス，ユール
ガスビャーグ，レアケ，スミド
シュパラー−ウルリヒ，アレクサンドル，ホヴァード
ゲイブ，マリア，バー，ノルドスコヴ
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ユニバーシティ オブ コペンハーゲン
ユニバーシティ オブ コペンハーゲン
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
JP2019565921A 2017-05-31 2018-05-31 長時間作用性ｇｉｐペプチド類似体 Pending JP2020521784A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17173628.3 2017-05-31
EP17173628 2017-05-31
PCT/EP2018/064355 WO2018220123A1 (en) 2017-05-31 2018-05-31 Long-acting gip peptide analogues

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JP2020521784A true JP2020521784A (ja) 2020-07-27
JP2020521784A5 JP2020521784A5 (enExample) 2021-07-26

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JP2019565921A Pending JP2020521784A (ja) 2017-05-31 2018-05-31 長時間作用性ｇｉｐペプチド類似体

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US (1) US11572399B2 (enExample)
EP (2) EP4361173A3 (enExample)
JP (1) JP2020521784A (enExample)
KR (1) KR102743887B1 (enExample)
CN (1) CN110691788B (enExample)
AU (1) AU2018276434B2 (enExample)
BR (1) BR112019025195A8 (enExample)
ES (1) ES2972848T3 (enExample)
PL (1) PL3630806T3 (enExample)
WO (1) WO2018220123A1 (enExample)

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WO2016034186A1 (en) 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
KR102743887B1 (ko) 2017-05-31 2024-12-19 유니버시티 오브 코펜하겐 장기-작용성 gip 펩타이드 유사체
MX2020011427A (es) 2018-05-04 2020-12-07 Novo Nordisk As Derivados del polipeptido insulinotropico dependiente de la glucosa (gip) y usos de estos.
WO2020115048A1 (en) * 2018-12-03 2020-06-11 Antag Therapeutics Aps Modified gip peptide analogues
MX2022006737A (es) * 2019-12-03 2022-06-14 Antag Therapeutics Aps Analogos peptidicos del peptido insulinotropico dependiente de glucosa (gip) optimizados.
WO2023139106A2 (en) 2022-01-18 2023-07-27 Novo Nordisk A/S Long-acting gipr antagonists

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JP2013518115A (ja) * 2010-01-27 2013-05-20 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐ｇｉｐアゴニスト複合体及び組成物
WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods
JP2016521253A (ja) * 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ

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WO2000020592A1 (en) 1998-10-07 2000-04-13 Medical College Of Georgia Research Institute, Inc. Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
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WO2010016936A1 (en) 2008-08-07 2010-02-11 Ipsen Pharma S.A.S. Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide
JP2011530508A (ja) 2008-08-07 2011-12-22 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ グルコース依存性インスリン分泌刺激ポリペプチドのアナログ
WO2010016944A2 (en) 2008-08-07 2010-02-11 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide (gip) modified at n-terminal
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CN103402536A (zh) 2010-12-22 2013-11-20 马克迪亚生物科技公司 用gip和glp-1受体活性的基于胰高血糖素的肽来治疗代谢异常和肥胖的方法
JP5914641B2 (ja) * 2011-06-10 2016-05-11 ベイジン・ハンミ・ファーマシューティカル・カンパニー・リミテッドＢｅｉｊｉｎｇ Ｈａｎｍｉ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． グルコース依存性インスリン分泌刺激ポリペプチドのアナログ、医薬組成物及びその使用
WO2012168464A1 (en) * 2011-06-10 2012-12-13 Universität Bern Imaging and treatment of neuroendocrine tumors with glucose - dependent insulinotropic polypeptide or analogues or antagonists thereof
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KR102743887B1 (ko) 2017-05-31 2024-12-19 유니버시티 오브 코펜하겐 장기-작용성 gip 펩타이드 유사체

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080009603A1 (en) * 1999-03-29 2008-01-10 Uutech Limited Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
JP2008500280A (ja) * 2004-02-25 2008-01-10 ユニバーシティ オブ アルスター 糖尿病、インスリン抵抗性、及び肥満症の治療のためのｇｉｐペプチド・アナログ
JP2010500996A (ja) * 2006-08-17 2010-01-14 アミリン・ファーマシューティカルズ，インコーポレイテッド 選択可能な特性を持つｄｐｐ−ｉｖ耐性ｇｉｐハイブリッドポリペプチド
JP2013518115A (ja) * 2010-01-27 2013-05-20 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐ｇｉｐアゴニスト複合体及び組成物
JP2016521253A (ja) * 2013-03-15 2016-07-21 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 持続性作用を有するプロドラッグ
WO2016034186A1 (en) * 2014-09-05 2016-03-10 University Of Copenhagen Gip peptide analogues
WO2016066744A2 (en) * 2014-10-29 2016-05-06 Zealand Pharma A/S Gip agonist compounds and methods

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CA3064510A1 (en) 2018-12-06
KR20200014287A (ko) 2020-02-10
KR102743887B1 (ko) 2024-12-19
BR112019025195A8 (pt) 2020-07-07
PL3630806T3 (pl) 2024-05-13
BR112019025195A2 (pt) 2020-06-23
AU2018276434B2 (en) 2021-12-16
CN110691788B (zh) 2024-05-31
EP3630806B1 (en) 2024-01-10
US20200087373A1 (en) 2020-03-19
EP4361173A2 (en) 2024-05-01
EP4361173A3 (en) 2024-07-03
CN110691788A (zh) 2020-01-14
ES2972848T3 (es) 2024-06-17
EP3630806A1 (en) 2020-04-08
WO2018220123A1 (en) 2018-12-06
AU2018276434A1 (en) 2020-01-02
US11572399B2 (en) 2023-02-07

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