KR102743887B1 - 장기-작용성 gip 펩타이드 유사체 - Google Patents
장기-작용성 gip 펩타이드 유사체 Download PDFInfo
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- KR102743887B1 KR102743887B1 KR1020197034279A KR20197034279A KR102743887B1 KR 102743887 B1 KR102743887 B1 KR 102743887B1 KR 1020197034279 A KR1020197034279 A KR 1020197034279A KR 20197034279 A KR20197034279 A KR 20197034279A KR 102743887 B1 KR102743887 B1 KR 102743887B1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (3)
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| EP17173628 | 2017-05-31 | ||
| EP17173628.3 | 2017-05-31 | ||
| PCT/EP2018/064355 WO2018220123A1 (en) | 2017-05-31 | 2018-05-31 | Long-acting gip peptide analogues |
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| KR20200014287A KR20200014287A (ko) | 2020-02-10 |
| KR102743887B1 true KR102743887B1 (ko) | 2024-12-19 |
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| KR1020197034279A Active KR102743887B1 (ko) | 2017-05-31 | 2018-05-31 | 장기-작용성 gip 펩타이드 유사체 |
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|---|---|
| US (1) | US11572399B2 (enExample) |
| EP (2) | EP3630806B1 (enExample) |
| JP (1) | JP2020521784A (enExample) |
| KR (1) | KR102743887B1 (enExample) |
| CN (1) | CN110691788B (enExample) |
| AU (1) | AU2018276434B2 (enExample) |
| BR (1) | BR112019025195A8 (enExample) |
| ES (1) | ES2972848T3 (enExample) |
| PL (1) | PL3630806T3 (enExample) |
| WO (1) | WO2018220123A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3189072B1 (en) | 2014-09-05 | 2018-07-18 | University of Copenhagen | Gip peptide analogues |
| BR112019025195A8 (pt) | 2017-05-31 | 2020-07-07 | Univ Copenhagen | análogos do peptídeo gip de ação prolongada |
| TWI707865B (zh) * | 2018-05-04 | 2020-10-21 | 丹麥商諾佛 儂迪克股份有限公司 | Gip衍生物及其用途 |
| US12297250B2 (en) * | 2018-12-03 | 2025-05-13 | Antag Therapeutics Aps | Modified GIP peptide analogues |
| JP7788376B2 (ja) * | 2019-12-03 | 2025-12-18 | アンタグ セラピューティクス エーピーエス | 最適化されたｇｉｐペプチド類縁体 |
| WO2023139106A2 (en) | 2022-01-18 | 2023-07-27 | Novo Nordisk A/S | Long-acting gipr antagonists |
Citations (2)
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|---|---|---|---|---|
| WO2016034186A1 (en) * | 2014-09-05 | 2016-03-10 | University Of Copenhagen | Gip peptide analogues |
| WO2016066744A2 (en) * | 2014-10-29 | 2016-05-06 | Zealand Pharma A/S | Gip agonist compounds and methods |
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| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| AU5518798A (en) | 1996-12-03 | 1998-06-29 | Trustees Of Boston University | Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) |
| JP3270761B2 (ja) | 1998-01-30 | 2002-04-02 | ノボ ノルディスク アクティーゼルスカブ | 注射器 |
| AU3247799A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
| ATE269103T1 (de) | 1998-03-13 | 2004-07-15 | Novo Nordisk As | Stabilisierte wässerige glukagonlösungen enthaltend detergenzien |
| AU6294899A (en) | 1998-10-07 | 2000-04-26 | Medical College Of Georgia Research Institute, Inc. | Glucose-dependent insulinotropic peptide for use as an osteotropic hormone |
| CN1495198A (zh) | 1998-12-07 | 2004-05-12 | �о���Ӧ�ÿ�ѧЭ��ɷ�����˾ | 胰高血糖素样肽-1的类似物 |
| US20050272652A1 (en) | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| GB0404124D0 (en) * | 2004-02-25 | 2004-03-31 | Univ Ulster | Antagonists of GIP |
| US6921748B1 (en) | 1999-03-29 | 2005-07-26 | Uutech Limited | Analogs of gastric inhibitory polypeptide and their use for treatment of diabetes |
| UA93662C2 (uk) | 2000-12-07 | 2011-03-10 | Эли Лилли Энд Компани | Гетерологічний пептидильований глюкагон-подібний білок та його застосування для виготовлення лікарського засобу для лікування пацієнтів, що страждають на ожиріння або інсулінонезалежний цукровий діабет |
| US20030232761A1 (en) | 2002-03-28 | 2003-12-18 | Hinke Simon A. | Novel analogues of glucose-dependent insulinotropic polypeptide |
| WO2004067548A2 (en) | 2003-01-31 | 2004-08-12 | Theratechnologies Inc. | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
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2018
- 2018-05-31 BR BR112019025195A patent/BR112019025195A8/pt unknown
- 2018-05-31 EP EP18728872.5A patent/EP3630806B1/en active Active
- 2018-05-31 CN CN201880036341.0A patent/CN110691788B/zh active Active
- 2018-05-31 PL PL18728872.5T patent/PL3630806T3/pl unknown
- 2018-05-31 JP JP2019565921A patent/JP2020521784A/ja active Pending
- 2018-05-31 US US16/617,698 patent/US11572399B2/en active Active
- 2018-05-31 AU AU2018276434A patent/AU2018276434B2/en active Active
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- 2018-05-31 KR KR1020197034279A patent/KR102743887B1/ko active Active
- 2018-05-31 WO PCT/EP2018/064355 patent/WO2018220123A1/en not_active Ceased
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| WO2016034186A1 (en) * | 2014-09-05 | 2016-03-10 | University Of Copenhagen | Gip peptide analogues |
| WO2016066744A2 (en) * | 2014-10-29 | 2016-05-06 | Zealand Pharma A/S | Gip agonist compounds and methods |
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| CA3064510A1 (en) | 2018-12-06 |
| CN110691788A (zh) | 2020-01-14 |
| KR20200014287A (ko) | 2020-02-10 |
| US20200087373A1 (en) | 2020-03-19 |
| EP3630806A1 (en) | 2020-04-08 |
| EP4361173A3 (en) | 2024-07-03 |
| CN110691788B (zh) | 2024-05-31 |
| AU2018276434B2 (en) | 2021-12-16 |
| AU2018276434A1 (en) | 2020-01-02 |
| BR112019025195A2 (pt) | 2020-06-23 |
| BR112019025195A8 (pt) | 2020-07-07 |
| US11572399B2 (en) | 2023-02-07 |
| EP4361173A2 (en) | 2024-05-01 |
| WO2018220123A1 (en) | 2018-12-06 |
| EP3630806B1 (en) | 2024-01-10 |
| PL3630806T3 (pl) | 2024-05-13 |
| ES2972848T3 (es) | 2024-06-17 |
| JP2020521784A (ja) | 2020-07-27 |
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