AU2017312951B2 - Methods for detecting AAV - Google Patents

Methods for detecting AAV Download PDF

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Publication number
AU2017312951B2
AU2017312951B2 AU2017312951A AU2017312951A AU2017312951B2 AU 2017312951 B2 AU2017312951 B2 AU 2017312951B2 AU 2017312951 A AU2017312951 A AU 2017312951A AU 2017312951 A AU2017312951 A AU 2017312951A AU 2017312951 B2 AU2017312951 B2 AU 2017312951B2
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Australia
Prior art keywords
aav
capsid
particle
aav2
amino acid
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AU2017312951A1 (en
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Xiaoying Jin
Lin Liu
Catherine R. O'riordan
Kate ZHANG
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Genzyme Corp
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Genzyme Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
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    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/075—Adenoviridae

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AU2017312951A 2016-08-15 2017-08-14 Methods for detecting AAV Active AU2017312951B2 (en)

Priority Applications (1)

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AU2024200349A AU2024200349A1 (en) 2016-08-15 2024-01-18 Methods for detecting AAV

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US201662375314P 2016-08-15 2016-08-15
US62/375,314 2016-08-15
PCT/US2017/046814 WO2018035059A1 (en) 2016-08-15 2017-08-14 Methods for detecting aav

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KR (5) KR102538037B1 (https=)
CN (2) CN118688363A (https=)
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EP3497207A1 (en) 2019-06-19
IL312792B1 (en) 2025-11-01
JP7021191B2 (ja) 2022-02-16
KR102738219B1 (ko) 2024-12-05
US20210041451A1 (en) 2021-02-11
KR20220107327A (ko) 2022-08-02
IL264819B1 (en) 2024-06-01
JP2024023460A (ja) 2024-02-21
EP3497207B1 (en) 2021-01-06
KR102425289B1 (ko) 2022-07-27
CN110168080B (zh) 2024-05-31
JP2019533803A (ja) 2019-11-21
CN118688363A (zh) 2024-09-24
IL312792A (en) 2024-07-01
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ES2863674T3 (es) 2021-10-11
US20250138024A1 (en) 2025-05-01
AU2017312951A1 (en) 2019-04-04
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IL312792B2 (en) 2026-03-01
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ZA201900945B (en) 2021-06-30
BR112019002934A2 (pt) 2019-05-14
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RU2019107207A (ru) 2020-09-15
US11698377B2 (en) 2023-07-11
CY1124364T1 (el) 2022-07-22
TW201825898A (zh) 2018-07-16
DK3497207T3 (da) 2021-03-22
CL2019000392A1 (es) 2019-05-10
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CA3033856A1 (en) 2018-02-22
WO2018035059A9 (en) 2019-03-14
RU2019107207A3 (https=) 2021-04-29
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US20240044910A1 (en) 2024-02-08
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US12298313B1 (en) 2025-05-13
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CR20190127A (es) 2019-06-25
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AU2024200349A1 (en) 2024-02-08
IL323969A (en) 2025-12-01
EP3851449A1 (en) 2021-07-21
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TW202309068A (zh) 2023-03-01
PH12019500316A1 (en) 2019-08-05
KR102538037B1 (ko) 2023-05-30
MA55748A (fr) 2022-03-02
IL264819B2 (en) 2024-10-01
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US12123880B2 (en) 2024-10-22

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