AU2017311542B2 - Alkaline stable Fc—binding proteins for affinity chromatography - Google Patents

Alkaline stable Fc—binding proteins for affinity chromatography Download PDF

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Publication number
AU2017311542B2
AU2017311542B2 AU2017311542A AU2017311542A AU2017311542B2 AU 2017311542 B2 AU2017311542 B2 AU 2017311542B2 AU 2017311542 A AU2017311542 A AU 2017311542A AU 2017311542 A AU2017311542 A AU 2017311542A AU 2017311542 B2 AU2017311542 B2 AU 2017311542B2
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protein
ala
binding
gln
binding protein
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AU2017311542A1 (en
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Erik Fiedler
Ulrich Haupts
Paul KNICK
Maren MEYSING
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Repligen Corp
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Repligen Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AU2017311542A 2016-08-11 2017-08-07 Alkaline stable Fc—binding proteins for affinity chromatography Active AU2017311542B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16183710 2016-08-11
EP16183710.9 2016-08-11
EP16205707 2016-12-21
EP16205707.9 2016-12-21
PCT/EP2017/069979 WO2018029158A1 (en) 2016-08-11 2017-08-07 Alkaline stable fc—binding proteins for affinity chromatography

Publications (2)

Publication Number Publication Date
AU2017311542A1 AU2017311542A1 (en) 2019-02-07
AU2017311542B2 true AU2017311542B2 (en) 2021-06-24

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AU2017311542A Active AU2017311542B2 (en) 2016-08-11 2017-08-07 Alkaline stable Fc—binding proteins for affinity chromatography
AU2017311541A Active AU2017311541B2 (en) 2016-08-11 2017-08-07 Novel alkaline stable immunoglobulin-binding proteins

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Application Number Title Priority Date Filing Date
AU2017311541A Active AU2017311541B2 (en) 2016-08-11 2017-08-07 Novel alkaline stable immunoglobulin-binding proteins

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US (4) US11014967B2 (enExample)
EP (4) EP4324840A3 (enExample)
JP (3) JP7181612B2 (enExample)
KR (3) KR20230133943A (enExample)
CN (4) CN109963864B (enExample)
AU (2) AU2017311542B2 (enExample)
CA (2) CA3030208A1 (enExample)
DK (1) DK3497117T5 (enExample)
LT (1) LT3497117T (enExample)
SG (1) SG11201901066UA (enExample)
WO (2) WO2018029157A1 (enExample)

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US20190177376A1 (en) 2019-06-13
US20210206815A1 (en) 2021-07-08
AU2017311542A1 (en) 2019-02-07
CN116333065A (zh) 2023-06-27
JP6951417B2 (ja) 2021-10-20
LT3497117T (lt) 2024-05-10
US20250051400A1 (en) 2025-02-13
CN117736281A (zh) 2024-03-22
WO2018029157A1 (en) 2018-02-15
EP4324840A3 (en) 2024-04-24
US20190300568A1 (en) 2019-10-03
AU2017311541B2 (en) 2020-08-13
JP2022160444A (ja) 2022-10-19
EP3497117B1 (en) 2024-01-24
JP2019531055A (ja) 2019-10-31
CN109963864B (zh) 2024-01-02
US11230576B2 (en) 2022-01-25
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