AU2017301887A1 - Anti-idiotypic antibodies against anti-CD19 antibodies - Google Patents
Anti-idiotypic antibodies against anti-CD19 antibodies Download PDFInfo
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- AU2017301887A1 AU2017301887A1 AU2017301887A AU2017301887A AU2017301887A1 AU 2017301887 A1 AU2017301887 A1 AU 2017301887A1 AU 2017301887 A AU2017301887 A AU 2017301887A AU 2017301887 A AU2017301887 A AU 2017301887A AU 2017301887 A1 AU2017301887 A1 AU 2017301887A1
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Classifications
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- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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Landscapes
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- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| TWI828334B (zh) * | 2016-09-28 | 2024-01-01 | 美商凱特製藥公司 | 抗原結合分子類和使用彼等之方法 |
| WO2018162376A1 (en) * | 2017-03-07 | 2018-09-13 | F. Hoffmann-La Roche Ag | Method for discovery of alternative antigen specific antibody variants |
| CA3070573A1 (en) * | 2017-07-29 | 2019-02-07 | Juno Therapeutics, Inc. | Reagents for expanding cells expressing recombinant receptors |
| WO2019089798A1 (en) * | 2017-10-31 | 2019-05-09 | Novartis Ag | Anti-car compositions and methods |
| CN108508200B (zh) * | 2018-04-18 | 2023-12-22 | 上海星湾生物技术有限公司 | 检测表达cd19 car的细胞的方法及其应用 |
| MX2021005366A (es) | 2018-11-08 | 2021-09-10 | Juno Therapeutics Inc | Metodos y combinaciones para el tratamiento y modulacion de celulas t. |
| GB201820444D0 (en) * | 2018-12-14 | 2019-01-30 | Adaptimmune Ltd | Marker for T cell expansion |
| JP2022529977A (ja) * | 2019-04-19 | 2022-06-27 | アロジーン セラピューティクス，インコーポレイテッド | ４ｇ７由来キメラ抗原受容体に対する抗体 |
| MX2022005145A (es) | 2019-10-30 | 2022-06-29 | Juno Therapeutics Gmbh | Dispositivos de estimulación y/o selección celular y método de uso. |
| JP2022554353A (ja) | 2019-11-07 | 2022-12-28 | ジュノー セラピューティクス インコーポレイテッド | Ｔ細胞療法と（ｓ）－３－［４－（４－モルホリン－４－イルメチル－ベンジルオキシ）－１－オキソ－１，３－ジヒドロ－イソインドール－２－イル］－ピペリジン－２，６－ジオンとの併用 |
| WO2021100585A1 (ja) * | 2019-11-20 | 2021-05-27 | 国立大学法人東海国立大学機構 | キメラ抗原受容体遺伝子改変リンパ球の調製方法 |
| CN110894238B (zh) * | 2019-11-25 | 2021-01-19 | 华道(上海)生物医药有限公司 | Car-t细胞的检测用单克隆抗体、试剂盒及应用 |
| CA3167251A1 (en) * | 2020-02-11 | 2021-08-19 | Lalit Kumar | Anti-idiotype antibodies targeting anti-cd19 chimeric antigen receptor |
| US20230228739A1 (en) * | 2020-07-03 | 2023-07-20 | Cellectis S.A. | Method for determining potency of chimeric antigen receptor expressing immune cells |
| JP2023533857A (ja) * | 2020-07-17 | 2023-08-04 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｋｌｋ２抗体に対する抗イディオタイプ抗体 |
| CN112143707A (zh) * | 2020-09-29 | 2020-12-29 | 广东先康达生物科技有限公司 | 一种治疗自身免疫细胞的免疫细胞及其应用 |
| EP4240756A1 (en) | 2020-11-04 | 2023-09-13 | Juno Therapeutics, Inc. | Cells expressing a chimeric receptor from a modified invariant cd3 immunoglobulin superfamily chain locus and related polynucleotides and methods |
| EP4263600A1 (en) | 2020-12-18 | 2023-10-25 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
| US20240108654A1 (en) | 2021-03-03 | 2024-04-04 | Juno Therapeutics, Inc. | Combination of a t cell therapy and a dgk inhibitor |
| KR20230159851A (ko) | 2021-03-22 | 2023-11-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 치료 세포 조성물의 효력을 결정하는 방법 |
| CN117321200A (zh) | 2021-03-22 | 2023-12-29 | 朱诺治疗学股份有限公司 | 评估病毒载体颗粒效力的方法 |
| JP2024513054A (ja) | 2021-03-29 | 2024-03-21 | ジュノー セラピューティクス インコーポレイテッド | リンパ腫の治療のためのｃａｒ ｔ細胞療法および免疫調節化合物の組合せ |
| WO2022234009A2 (en) | 2021-05-06 | 2022-11-10 | Juno Therapeutics Gmbh | Methods for stimulating and transducing t cells |
| TW202321311A (zh) * | 2021-08-02 | 2023-06-01 | 日商諾伊爾免疫生物科技股份有限公司 | 與scFv等之連接子結合的抗體 |
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2017
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| WO2018023100A3 (en) | 2018-03-08 |
| MA45784A (fr) | 2019-06-05 |
| CN117903316A (zh) | 2024-04-19 |
| JP7062640B2 (ja) | 2022-05-06 |
| KR20190044626A (ko) | 2019-04-30 |
| US20240018268A1 (en) | 2024-01-18 |
| JP2019527553A (ja) | 2019-10-03 |
| MX2019001184A (es) | 2019-09-26 |
| WO2018023100A2 (en) | 2018-02-01 |
| CN110088133A (zh) | 2019-08-02 |
| JP2022084583A (ja) | 2022-06-07 |
| CN110088133B (zh) | 2023-12-08 |
| EP3491024A2 (en) | 2019-06-05 |
| KR20230107408A (ko) | 2023-07-14 |
| KR102553195B1 (ko) | 2023-07-07 |
| RU2019105532A (ru) | 2020-08-28 |
| BR112019001327A2 (pt) | 2019-04-30 |
| CA3031734A1 (en) | 2018-02-01 |
| RU2019105532A3 (zh) | 2020-10-22 |
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