AU2016252869B2 - Pyrazole compounds and method for making and using the compounds - Google Patents

Pyrazole compounds and method for making and using the compounds Download PDF

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Publication number
AU2016252869B2
AU2016252869B2 AU2016252869A AU2016252869A AU2016252869B2 AU 2016252869 B2 AU2016252869 B2 AU 2016252869B2 AU 2016252869 A AU2016252869 A AU 2016252869A AU 2016252869 A AU2016252869 A AU 2016252869A AU 2016252869 B2 AU2016252869 B2 AU 2016252869B2
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Prior art keywords
pyrazol
carboxamide
pyridin
furan
thiazole
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AU2016252869A1 (en
Inventor
Yan Chen
Thilo Heckrodt
Ryan Kelley
Hui Li
Jack Maung
Darren Mcmurtrie
Rajinder Singh
Vanessa Taylor
Kin Tso
Rose Yen
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Rigel Pharmaceuticals Inc
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Rigel Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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