AU2014311148B2 - Vancomycin derivative, and preparation method and application thereof - Google Patents

Vancomycin derivative, and preparation method and application thereof Download PDF

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Publication number
AU2014311148B2
AU2014311148B2 AU2014311148A AU2014311148A AU2014311148B2 AU 2014311148 B2 AU2014311148 B2 AU 2014311148B2 AU 2014311148 A AU2014311148 A AU 2014311148A AU 2014311148 A AU2014311148 A AU 2014311148A AU 2014311148 B2 AU2014311148 B2 AU 2014311148B2
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AU
Australia
Prior art keywords
alkyl
coora
vancomycin
iii
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2014311148A
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English (en)
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AU2014311148A1 (en
Inventor
Min Ge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acesys Pharma Inc
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Acesys Pharma Inc
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Publication date
Application filed by Acesys Pharma Inc filed Critical Acesys Pharma Inc
Publication of AU2014311148A1 publication Critical patent/AU2014311148A1/en
Application granted granted Critical
Publication of AU2014311148B2 publication Critical patent/AU2014311148B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2014311148A 2013-08-19 2014-04-22 Vancomycin derivative, and preparation method and application thereof Ceased AU2014311148B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2013103615770 2013-08-19
CN201310361577.0A CN104418941B (zh) 2013-08-19 2013-08-19 万古霉素衍生物、制备方法及其应用
PCT/CN2014/075905 WO2015024389A1 (zh) 2013-08-19 2014-04-22 万古霉素衍生物、制备方法及其应用

Publications (2)

Publication Number Publication Date
AU2014311148A1 AU2014311148A1 (en) 2016-03-10
AU2014311148B2 true AU2014311148B2 (en) 2017-07-13

Family

ID=52483023

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014311148A Ceased AU2014311148B2 (en) 2013-08-19 2014-04-22 Vancomycin derivative, and preparation method and application thereof

Country Status (15)

Country Link
US (1) US9828413B2 (cg-RX-API-DMAC7.html)
EP (1) EP3037431A4 (cg-RX-API-DMAC7.html)
JP (1) JP6452698B2 (cg-RX-API-DMAC7.html)
KR (1) KR20160043094A (cg-RX-API-DMAC7.html)
CN (2) CN104418941B (cg-RX-API-DMAC7.html)
AU (1) AU2014311148B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016003491A2 (cg-RX-API-DMAC7.html)
CA (1) CA2921080A1 (cg-RX-API-DMAC7.html)
EA (1) EA029855B1 (cg-RX-API-DMAC7.html)
IL (1) IL244140A0 (cg-RX-API-DMAC7.html)
MX (1) MX2016002190A (cg-RX-API-DMAC7.html)
NZ (1) NZ717098A (cg-RX-API-DMAC7.html)
SG (1) SG11201601127TA (cg-RX-API-DMAC7.html)
WO (1) WO2015024389A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201601343B (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
CN105985412A (zh) * 2015-02-28 2016-10-05 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
CN107365359B (zh) * 2017-07-17 2021-06-04 昆明理工大学 一种万古霉素手性功能单体合成方法
CN107759671A (zh) * 2017-09-11 2018-03-06 昆明理工大学 水相中合成万古霉素手性功能单体的方法
USD922342S1 (en) 2018-10-05 2021-06-15 Samsung Electronics Co., Ltd. Television receiver
USD906992S1 (en) 2018-12-13 2021-01-05 Samsung Electronics Co., Ltd. Television receiver
CN112079902B (zh) * 2019-06-12 2025-05-06 迪普深合医药研发(上海)有限公司 万古霉素衍生物、其中间体、制备方法、组合物及用途
WO2021113115A1 (en) * 2019-12-04 2021-06-10 University Of Massachusetts Compositions and methods for on-demand release of antimicrobial agents

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0435503A1 (en) * 1989-12-13 1991-07-03 Eli Lilly And Company Improvements in or relating to gylcopeptide derivatives
EP0667353A1 (en) * 1994-01-28 1995-08-16 Eli Lilly And Company Glycopeptide antibiotic derivatives
WO2003018608A2 (en) * 2001-08-24 2003-03-06 Theravance, Inc. Process for purifying glycopeptide phosphonate derivatives
EP1818340A1 (en) * 2004-11-29 2007-08-15 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
CA2337103A1 (en) * 1998-07-14 2000-01-27 Robert Kerns Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
GB0026924D0 (en) * 2000-11-03 2000-12-20 Univ Cambridge Tech Antibacterial agents
US8193312B2 (en) 2004-01-28 2012-06-05 The Regents Of The University Of California Bone morphogenic protein binding peptide
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0435503A1 (en) * 1989-12-13 1991-07-03 Eli Lilly And Company Improvements in or relating to gylcopeptide derivatives
EP0667353A1 (en) * 1994-01-28 1995-08-16 Eli Lilly And Company Glycopeptide antibiotic derivatives
WO2003018608A2 (en) * 2001-08-24 2003-03-06 Theravance, Inc. Process for purifying glycopeptide phosphonate derivatives
EP1818340A1 (en) * 2004-11-29 2007-08-15 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LI LEI, "Research on the Design and Synthesis of Vancomycin Derivatives as New Antibiotics", MASTER THESIS, NANJING UNIVERSITY, CN, (20110401), pages 1 -69 *

Also Published As

Publication number Publication date
IL244140A0 (en) 2016-04-21
CN104418941A (zh) 2015-03-18
WO2015024389A1 (zh) 2015-02-26
BR112016003491A2 (pt) 2017-09-12
EP3037431A4 (en) 2017-04-19
MX2016002190A (es) 2016-11-25
EA201690396A1 (ru) 2016-06-30
CA2921080A1 (en) 2015-02-26
JP2016528262A (ja) 2016-09-15
AU2014311148A1 (en) 2016-03-10
EP3037431A1 (en) 2016-06-29
KR20160043094A (ko) 2016-04-20
CN107759672A (zh) 2018-03-06
SG11201601127TA (en) 2016-03-30
US20160200768A1 (en) 2016-07-14
US9828413B2 (en) 2017-11-28
CN104418941B (zh) 2017-11-07
ZA201601343B (en) 2017-05-31
NZ717098A (en) 2017-06-30
JP6452698B2 (ja) 2019-01-16
EA029855B1 (ru) 2018-05-31

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired