MX2016002190A - Derivado de vancomicina, y procedimiento de preparacion y aplicacion del mismo. - Google Patents

Derivado de vancomicina, y procedimiento de preparacion y aplicacion del mismo.

Info

Publication number
MX2016002190A
MX2016002190A MX2016002190A MX2016002190A MX2016002190A MX 2016002190 A MX2016002190 A MX 2016002190A MX 2016002190 A MX2016002190 A MX 2016002190A MX 2016002190 A MX2016002190 A MX 2016002190A MX 2016002190 A MX2016002190 A MX 2016002190A
Authority
MX
Mexico
Prior art keywords
preparation
vancomycin derivative
application
vancomycin
derivative
Prior art date
Application number
MX2016002190A
Other languages
English (en)
Inventor
Ge Min
Original Assignee
Acesys Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acesys Pharma Inc filed Critical Acesys Pharma Inc
Publication of MX2016002190A publication Critical patent/MX2016002190A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona un derivado de vancomicina, y un método de preparación y una aplicación del mismo; el derivado de vancomicina de la presente invención se obtiene al introducir una porción glicerato entre un derivado de vancomicina y un grupo de modificación liposoluble y tiene liposolubilidad reducida y solubilidad en agua mejorada, reduciendo de este modo un efecto secundario en el aspecto cardiovascular.
MX2016002190A 2013-08-19 2014-04-22 Derivado de vancomicina, y procedimiento de preparacion y aplicacion del mismo. MX2016002190A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310361577.0A CN104418941B (zh) 2013-08-19 2013-08-19 万古霉素衍生物、制备方法及其应用
PCT/CN2014/075905 WO2015024389A1 (zh) 2013-08-19 2014-04-22 万古霉素衍生物、制备方法及其应用

Publications (1)

Publication Number Publication Date
MX2016002190A true MX2016002190A (es) 2016-11-25

Family

ID=52483023

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002190A MX2016002190A (es) 2013-08-19 2014-04-22 Derivado de vancomicina, y procedimiento de preparacion y aplicacion del mismo.

Country Status (15)

Country Link
US (1) US9828413B2 (es)
EP (1) EP3037431A4 (es)
JP (1) JP6452698B2 (es)
KR (1) KR20160043094A (es)
CN (2) CN107759672A (es)
AU (1) AU2014311148B2 (es)
BR (1) BR112016003491A2 (es)
CA (1) CA2921080A1 (es)
EA (1) EA029855B1 (es)
IL (1) IL244140A0 (es)
MX (1) MX2016002190A (es)
NZ (1) NZ717098A (es)
SG (1) SG11201601127TA (es)
WO (1) WO2015024389A1 (es)
ZA (1) ZA201601343B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107759672A (zh) * 2013-08-19 2018-03-06 南京爱斯药业有限公司 万古霉素衍生物、制备方法及其应用
CN105985412A (zh) * 2015-02-28 2016-10-05 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
CN107365359B (zh) * 2017-07-17 2021-06-04 昆明理工大学 一种万古霉素手性功能单体合成方法
CN107759671A (zh) * 2017-09-11 2018-03-06 昆明理工大学 水相中合成万古霉素手性功能单体的方法
USD922342S1 (en) 2018-10-05 2021-06-15 Samsung Electronics Co., Ltd. Television receiver
USD906992S1 (en) 2018-12-13 2021-01-05 Samsung Electronics Co., Ltd. Television receiver
CN112079902A (zh) * 2019-06-12 2020-12-15 中国科学院上海有机化学研究所 万古霉素衍生物、其中间体、制备方法、组合物及用途
WO2021113115A1 (en) * 2019-12-04 2021-06-10 University Of Massachusetts Compositions and methods for on-demand release of antimicrobial agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ236393A (en) * 1989-12-13 1992-05-26 Lilly Co Eli N-alkylated glycopeptide derivatives prepared from antibiotics a82846 series and pa-42867-a; pharmaceutical compositions
MY128335A (en) * 1994-01-28 2007-01-31 Lilly Co Eli Glycopeptide antibiotic derivatives
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
JP2002520422A (ja) * 1998-07-14 2002-07-09 プリンストン ユニバーシティ グリコペプチド抗生物質、グリコペプチド抗生物質のコンビナトリアルライブラリーおよびその作成方法
GB0026924D0 (en) 2000-11-03 2000-12-20 Univ Cambridge Tech Antibacterial agents
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
US8193312B2 (en) 2004-01-28 2012-06-05 The Regents Of The University Of California Bone morphogenic protein binding peptide
CA2588285A1 (en) * 2004-11-29 2006-06-01 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
CN107759672A (zh) * 2013-08-19 2018-03-06 南京爱斯药业有限公司 万古霉素衍生物、制备方法及其应用

Also Published As

Publication number Publication date
EA029855B1 (ru) 2018-05-31
EA201690396A1 (ru) 2016-06-30
SG11201601127TA (en) 2016-03-30
AU2014311148A1 (en) 2016-03-10
CN104418941B (zh) 2017-11-07
JP2016528262A (ja) 2016-09-15
KR20160043094A (ko) 2016-04-20
CN104418941A (zh) 2015-03-18
AU2014311148B2 (en) 2017-07-13
IL244140A0 (en) 2016-04-21
JP6452698B2 (ja) 2019-01-16
WO2015024389A1 (zh) 2015-02-26
ZA201601343B (en) 2017-05-31
BR112016003491A2 (pt) 2017-09-12
CA2921080A1 (en) 2015-02-26
EP3037431A1 (en) 2016-06-29
CN107759672A (zh) 2018-03-06
NZ717098A (en) 2017-06-30
US20160200768A1 (en) 2016-07-14
US9828413B2 (en) 2017-11-28
EP3037431A4 (en) 2017-04-19

Similar Documents

Publication Publication Date Title
MX2016002190A (es) Derivado de vancomicina, y procedimiento de preparacion y aplicacion del mismo.
MX2016017355A (es) Lipido que comprende acido docosapentaenoico.
PH12016502586A1 (en) Lipid comprising docosapentaenoic acid
PH12014501453B1 (en) Method of reducing exercise-induced joint pain in non-arthritic mammals
WO2014083438A3 (en) Nitric oxide increasing nutritional supplements and methods
MX2018004831A (es) Metodos para confeccionar formas fucosiladas y afucosiladas de una proteina.
PH12015500900A1 (en) A stabilized pemetrexed formulation
ZA201604328B (en) 1,2-naphthoquinone derivative and method for preparing same
MX2016005205A (es) Composiciones de proteina de suero lácteo desnaturalizada con alto contenido protéico, que contienen cmp, productos que las contienen y usos de las mismas.
EA201691648A1 (ru) Способ получения противогрибковых соединений
EA201691649A1 (ru) Способ получения противогрибковых соединений
MY193444A (en) Cell-free production of ribonucleic acid
MY166184A (en) Impregnation type puffed food and method for producing same
EP2889378A4 (en) PROCESS FOR THE PREPARATION OF L-LYSINE HYDROXYLASE AND HYDROXY-L-LYSINE THEREWITH AND METHOD OF PREPARING HYDROXY-L-PIPECOLIC ACID
EP3289339A4 (en) Method to estimate water saturation in electromagnetic measurements
PL3091005T3 (pl) Pochodna 1,2-naftochinonu i sposób jej wytwarzania
WO2014141294A3 (en) An improved process for the synthesis of melphalan and the hydrochloride salt
MX2016008821A (es) Composiciones lacteas fermentadas coladas y aireadas.
MX2015016603A (es) Composiciones de corticosteroides.
EA201692246A1 (ru) Способ получения 2,6-диметилбензохинона
EP3118207A4 (en) Inclusion compound of 3',5'-cyclicdiadenylic acid, and method for producing same
WO2014173416A3 (en) An aerated cheese product
EP3345992A4 (en) METHOD FOR THE PRODUCTION OF MEAT, WHICH IS POSSIBLE TO REDUCE THE INGREDIENT OF SATURATED FATTY ACIDS
PH12018502207A1 (en) Methods of manufacturing nutritional formulations
EP3068495A4 (en) Retinoid double conjugate compounds, compositions thereof, and methods for treating of skin conditions