AU2013250711A1 - Long-acting oxyntomodulin variants and methods of producing same - Google Patents
Long-acting oxyntomodulin variants and methods of producing same Download PDFInfo
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- AU2013250711A1 AU2013250711A1 AU2013250711A AU2013250711A AU2013250711A1 AU 2013250711 A1 AU2013250711 A1 AU 2013250711A1 AU 2013250711 A AU2013250711 A AU 2013250711A AU 2013250711 A AU2013250711 A AU 2013250711A AU 2013250711 A1 AU2013250711 A1 AU 2013250711A1
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- Prior art keywords
- ctp
- glp
- another embodiment
- glucagon receptor
- agonist
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- A—HUMAN NECESSITIES
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- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261635483P | 2012-04-19 | 2012-04-19 | |
| US61/635,483 | 2012-04-19 | ||
| PCT/IL2013/050332 WO2013157002A1 (en) | 2012-04-19 | 2013-04-17 | Long-acting oxyntomodulin variants and methods of producing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2013250711A1 true AU2013250711A1 (en) | 2014-11-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013250711A Abandoned AU2013250711A1 (en) | 2012-04-19 | 2013-04-17 | Long-acting oxyntomodulin variants and methods of producing same |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9522945B2 (https=) |
| EP (1) | EP2838552A4 (https=) |
| JP (1) | JP2015520128A (https=) |
| KR (1) | KR20150008137A (https=) |
| CN (1) | CN104487082A (https=) |
| AU (1) | AU2013250711A1 (https=) |
| BR (1) | BR112014025951A2 (https=) |
| CA (1) | CA2870650A1 (https=) |
| CL (1) | CL2014002791A1 (https=) |
| CO (1) | CO7200249A2 (https=) |
| EA (1) | EA201491898A1 (https=) |
| HK (1) | HK1207564A1 (https=) |
| IL (1) | IL235184A0 (https=) |
| MX (1) | MX2014012625A (https=) |
| MY (1) | MY167814A (https=) |
| PE (1) | PE20142405A1 (https=) |
| SG (1) | SG11201406671RA (https=) |
| WO (1) | WO2013157002A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10221228B2 (en) | 2006-02-03 | 2019-03-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
| US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US20140113860A1 (en) | 2006-02-03 | 2014-04-24 | Prolor Biotech Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US9458444B2 (en) | 2006-02-03 | 2016-10-04 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
| US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US12203113B2 (en) | 2009-07-09 | 2025-01-21 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
| US10166295B2 (en) | 2011-06-02 | 2019-01-01 | Opko Biologics Ltd. | Pegylated OXM variants |
| UA126465C2 (uk) | 2011-06-10 | 2022-10-12 | Ханмі Сайенс Ко., Лтд. | Пептид, що має активність оксинтомодуліну, та фармацевтична композиція для лікування ожиріння, яка його містить |
| RU2607365C2 (ru) | 2011-06-17 | 2017-01-10 | Ханми Сайенс Ко., Лтд. | Конъюгат, содержащий оксинтомодулин и фрагмент иммуноглобулина, и его применение |
| HK1207564A1 (en) | 2012-04-19 | 2016-02-05 | Opko Biologics Ltd | Long-acting oxyntomodulin variants and methods of producing same |
| EA201492269A1 (ru) | 2012-06-04 | 2016-02-29 | Опко Байолоджикс Лтд. | Пегилированные варианты oxm |
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- 2013-04-17 HK HK15108167.3A patent/HK1207564A1/xx unknown
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- 2013-04-17 MY MYPI2014002960A patent/MY167814A/en unknown
- 2013-04-17 WO PCT/IL2013/050332 patent/WO2013157002A1/en not_active Ceased
- 2013-04-17 CA CA2870650A patent/CA2870650A1/en not_active Abandoned
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- 2013-04-17 US US14/395,441 patent/US9522945B2/en active Active
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- 2014-11-11 CO CO14249267A patent/CO7200249A2/es unknown
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| MX2014012625A (es) | 2015-05-15 |
| CN104487082A (zh) | 2015-04-01 |
| BR112014025951A2 (pt) | 2017-07-11 |
| SG11201406671RA (en) | 2014-11-27 |
| EA201491898A1 (ru) | 2015-08-31 |
| CA2870650A1 (en) | 2013-10-24 |
| US20150072924A1 (en) | 2015-03-12 |
| WO2013157002A1 (en) | 2013-10-24 |
| MY167814A (en) | 2018-09-26 |
| CO7200249A2 (es) | 2015-02-27 |
| EP2838552A4 (en) | 2016-05-18 |
| PE20142405A1 (es) | 2015-01-25 |
| US20170088598A1 (en) | 2017-03-30 |
| IL235184A0 (en) | 2014-12-31 |
| JP2015520128A (ja) | 2015-07-16 |
| KR20150008137A (ko) | 2015-01-21 |
| US9522945B2 (en) | 2016-12-20 |
| EP2838552A1 (en) | 2015-02-25 |
| CL2014002791A1 (es) | 2015-06-05 |
| HK1207564A1 (en) | 2016-02-05 |
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