AU2013248312B2 - Method for increasing the secretion of recombinant proteins - Google Patents

Method for increasing the secretion of recombinant proteins Download PDF

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Publication number
AU2013248312B2
AU2013248312B2 AU2013248312A AU2013248312A AU2013248312B2 AU 2013248312 B2 AU2013248312 B2 AU 2013248312B2 AU 2013248312 A AU2013248312 A AU 2013248312A AU 2013248312 A AU2013248312 A AU 2013248312A AU 2013248312 B2 AU2013248312 B2 AU 2013248312B2
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concentration
medium
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knop
cell
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AU2013248312A1 (en
Inventor
Doreen Claußnitzer
Wolfgang Jost
Mathias Knappenberger
Andreas Schaaf
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Eleva GmbH
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Greenovation Biotech GmbH
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12Unicellular algae; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0025Culture media for plant cell or plant tissue culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/60Buffer, e.g. pH regulation, osmotic pressure

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU2013248312A 2012-04-17 2013-04-17 Method for increasing the secretion of recombinant proteins Active AU2013248312B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12164458.7A EP2653548A1 (de) 2012-04-17 2012-04-17 Verfahren zur Erhöhung der Sekretion rekombinanter Proteine
EP12164458.7 2012-04-17
PCT/EP2013/057956 WO2013156504A1 (de) 2012-04-17 2013-04-17 Verfahren zur erhöhung der sekretion rekombinanter proteine

Publications (2)

Publication Number Publication Date
AU2013248312A1 AU2013248312A1 (en) 2014-10-23
AU2013248312B2 true AU2013248312B2 (en) 2018-08-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013248312A Active AU2013248312B2 (en) 2012-04-17 2013-04-17 Method for increasing the secretion of recombinant proteins

Country Status (19)

Country Link
US (1) US9850513B2 (enExample)
EP (2) EP2653548A1 (enExample)
JP (1) JP6215305B2 (enExample)
KR (1) KR102028738B1 (enExample)
CN (1) CN104379750A (enExample)
AU (1) AU2013248312B2 (enExample)
BR (1) BR112014025306B1 (enExample)
CA (1) CA2870587A1 (enExample)
DK (1) DK2839012T3 (enExample)
ES (1) ES2755973T3 (enExample)
HR (1) HRP20191876T1 (enExample)
IL (1) IL235052B (enExample)
IN (1) IN2014DN08664A (enExample)
LT (1) LT2839012T (enExample)
MX (1) MX353243B (enExample)
PL (1) PL2839012T3 (enExample)
PT (1) PT2839012T (enExample)
SI (1) SI2839012T1 (enExample)
WO (1) WO2013156504A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2729732B2 (ja) 1992-10-05 1998-03-18 新日本製鐵株式会社 底つき容器の製造方法
EP3808854A1 (de) 2019-10-17 2021-04-21 eleva GmbH Verfahren zur gewinnung von material von pflanzenzelloberflächen
BR112022012467A2 (pt) * 2020-01-31 2022-09-06 Chugai Pharmaceutical Co Ltd Método para produção de composição contendo polipeptídeo com coloração suprimida

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100035327A1 (en) * 2008-08-11 2010-02-11 Ann Marie Steele Use of rice-derived products in a universal cell culture medium

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63226281A (ja) * 1986-12-26 1988-09-20 Seitai Kinou Riyou Kagakuhin Shinseizou Gijutsu Kenkyu Kumiai 組織培養方法
JP2000245470A (ja) * 1999-02-26 2000-09-12 Noda Inst For Scient Res 植物細胞間液による外来ポリペプチドの製造方法
DE19947290A1 (de) 1999-10-01 2001-04-19 Greenovation Pflanzenbiotechno Verfahren zur Herstellung proteinöser Substanzen
CN1109750C (zh) * 2000-08-15 2003-05-28 中国水产科学研究院黄海水产研究所 一种新型低温碱性蛋白酶、制造方法、应用和产生该蛋白酶的微生物
WO2003083066A2 (en) 2002-03-27 2003-10-09 Immunex Corporation Methods for increasing polypeptide production
US8637316B2 (en) * 2008-07-16 2014-01-28 Sumitomo Chemical Company, Limited Glycinin signal sequence for producing secreted proteins in plants

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100035327A1 (en) * 2008-08-11 2010-02-11 Ann Marie Steele Use of rice-derived products in a universal cell culture medium

Also Published As

Publication number Publication date
JP6215305B2 (ja) 2017-10-18
US9850513B2 (en) 2017-12-26
KR102028738B1 (ko) 2019-10-04
MX2014012407A (es) 2015-04-09
EP2653548A1 (de) 2013-10-23
PL2839012T3 (pl) 2020-05-18
BR112014025306B1 (pt) 2021-11-30
CA2870587A1 (en) 2013-10-24
ES2755973T3 (es) 2020-04-24
SI2839012T1 (sl) 2019-12-31
BR112014025306A2 (pt) 2017-06-20
US20150079632A1 (en) 2015-03-19
MX353243B (es) 2018-01-05
AU2013248312A1 (en) 2014-10-23
KR20150014454A (ko) 2015-02-06
EP2839012B1 (de) 2019-08-28
WO2013156504A1 (de) 2013-10-24
EP2839012A1 (de) 2015-02-25
PT2839012T (pt) 2019-12-05
IN2014DN08664A (enExample) 2015-05-22
JP2015514408A (ja) 2015-05-21
LT2839012T (lt) 2019-11-25
CN104379750A (zh) 2015-02-25
IL235052B (en) 2019-12-31
IL235052A0 (en) 2014-12-31
DK2839012T3 (da) 2019-10-21
HRP20191876T1 (hr) 2019-12-27

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