AU2013234860B2 - Method of producing a recombinant peptide - Google Patents

Method of producing a recombinant peptide Download PDF

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Publication number
AU2013234860B2
AU2013234860B2 AU2013234860A AU2013234860A AU2013234860B2 AU 2013234860 B2 AU2013234860 B2 AU 2013234860B2 AU 2013234860 A AU2013234860 A AU 2013234860A AU 2013234860 A AU2013234860 A AU 2013234860A AU 2013234860 B2 AU2013234860 B2 AU 2013234860B2
Authority
AU
Australia
Prior art keywords
peptide
vsdl
fusion polypeptide
cleavage site
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2013234860A
Other languages
English (en)
Other versions
AU2013234860A1 (en
Inventor
Stan Bastiras
Angelo Guidolin
Ben HUNT
Muhammad Saif Raisheed
Reza ZAREIE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madeleine Pharmaceuticals Pty Ltd
Original Assignee
Madeleine Pharmaceuticals Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madeleine Pharmaceuticals Pty Ltd filed Critical Madeleine Pharmaceuticals Pty Ltd
Publication of AU2013234860A1 publication Critical patent/AU2013234860A1/en
Application granted granted Critical
Publication of AU2013234860B2 publication Critical patent/AU2013234860B2/en
Priority to AU2016100212A priority Critical patent/AU2016100212A4/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2013234860A 2012-03-19 2013-03-19 Method of producing a recombinant peptide Ceased AU2013234860B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016100212A AU2016100212A4 (en) 2012-03-19 2016-02-29 Method of producing a recombinant peptide

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261612817P 2012-03-19 2012-03-19
US61/612,817 2012-03-19
PCT/AU2013/000273 WO2013138850A1 (en) 2012-03-19 2013-03-19 Method of producing a recombinant peptide

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016100212A Division AU2016100212A4 (en) 2012-03-19 2016-02-29 Method of producing a recombinant peptide

Publications (2)

Publication Number Publication Date
AU2013234860A1 AU2013234860A1 (en) 2014-10-16
AU2013234860B2 true AU2013234860B2 (en) 2016-01-21

Family

ID=49221695

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2013234860A Ceased AU2013234860B2 (en) 2012-03-19 2013-03-19 Method of producing a recombinant peptide
AU2016100212A Ceased AU2016100212A4 (en) 2012-03-19 2016-02-29 Method of producing a recombinant peptide

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016100212A Ceased AU2016100212A4 (en) 2012-03-19 2016-02-29 Method of producing a recombinant peptide

Country Status (8)

Country Link
US (1) US20150315259A1 (enExample)
EP (1) EP2839010B1 (enExample)
JP (1) JP2015510770A (enExample)
KR (1) KR20140148420A (enExample)
CN (2) CN104364378A (enExample)
AU (2) AU2013234860B2 (enExample)
SG (1) SG11201405721VA (enExample)
WO (1) WO2013138850A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8947194B2 (en) 2009-05-26 2015-02-03 Solaredge Technologies Ltd. Theft detection and prevention in a power generation system
MX2020010071A (es) * 2018-03-29 2021-01-08 Contrafect Corp Polipeptidos anti-microbianos, derivados de bacteriofago, y sus usos contra bacterias gram negativas.
CN113121637B (zh) * 2020-01-15 2022-06-14 鲁南制药集团股份有限公司 一种重组蛋白的分离纯化方法
CN116981680A (zh) 2021-01-14 2023-10-31 生物催化剂有限责任公司 用于肽生产的组合物和方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000017336A1 (en) * 1998-09-19 2000-03-30 Sang Jun Lee Dna cassette encoding a multimer of a biologically active peptide and a cleavable linker attached thereto and process for preparing the biologically active peptide
US6558924B1 (en) * 1997-08-07 2003-05-06 Creative Peptides Sweden Ab Recombinant expression of insulin C-peptide
EP1408050A1 (en) * 2001-07-19 2004-04-14 Shanghai Hua-Yi Bio-Tech Lab A method of producing glucagon-like peptide 1(glp-1)7-36 and an glp-1 analogue
WO2004047871A2 (en) * 2002-11-26 2004-06-10 Nobex Corporation Modified naturetic compounds, conjugates, and uses thereof
WO2006128492A1 (en) * 2005-06-02 2006-12-07 Entelechon Gmbh Artificial protein, method for absolute quantification of proteins and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691310A (en) * 1987-09-29 1997-11-25 Vesely; David L. Methods of treatment using proANF peptides
CN1242062C (zh) * 1998-07-10 2006-02-15 赛欧斯公司 生产等电点高于8或低于5的多肽的方法
US6759510B1 (en) * 2000-06-30 2004-07-06 Becton, Dickinson And Company Peptides for use in culture media
ATE457355T1 (de) * 2002-05-24 2010-02-15 Medtronic Inc Verfahren und dna-konstrukte zur produktion von polypeptiden mit hoher ausbeute
EP1727556A2 (en) * 2004-02-17 2006-12-06 University Of South Florida Materials and methods for treatment of inflammatory and cell proliferation disorders
WO2009043468A2 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of corticotropin-releasing factor as a therapeutic agent
RU2451750C2 (ru) * 2007-09-24 2012-05-27 Общество С Ограниченной Ответственностью "Герофарм" Способ получения рекомбинантного с-пептида проинсулина человека
US8527211B2 (en) * 2008-06-18 2013-09-03 Reza Zareie Method to produce recombinant MBP8298 and other polypeptides by nucleotide structure optimization
CN102575264A (zh) * 2009-09-18 2012-07-11 瑟莱克斯公司 增加的转基因表达和加工的产品和方法
WO2012019237A1 (en) * 2010-08-12 2012-02-16 Madeleine Pharmaceuticals Pty Ltd Therapeutic method for treating congestive heart failure
EP2678002A2 (en) * 2011-02-25 2014-01-01 Medtronic, Inc. Therapy for kidney disease and/or heart failure

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558924B1 (en) * 1997-08-07 2003-05-06 Creative Peptides Sweden Ab Recombinant expression of insulin C-peptide
WO2000017336A1 (en) * 1998-09-19 2000-03-30 Sang Jun Lee Dna cassette encoding a multimer of a biologically active peptide and a cleavable linker attached thereto and process for preparing the biologically active peptide
EP1408050A1 (en) * 2001-07-19 2004-04-14 Shanghai Hua-Yi Bio-Tech Lab A method of producing glucagon-like peptide 1(glp-1)7-36 and an glp-1 analogue
WO2004047871A2 (en) * 2002-11-26 2004-06-10 Nobex Corporation Modified naturetic compounds, conjugates, and uses thereof
WO2006128492A1 (en) * 2005-06-02 2006-12-07 Entelechon Gmbh Artificial protein, method for absolute quantification of proteins and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LENNICK, M. et al., Gene, 1987, Vol. 61, pages 103-112 *

Also Published As

Publication number Publication date
JP2015510770A (ja) 2015-04-13
US20150315259A1 (en) 2015-11-05
AU2013234860A1 (en) 2014-10-16
SG11201405721VA (en) 2014-10-30
EP2839010A1 (en) 2015-02-25
AU2016100212A4 (en) 2016-04-14
EP2839010B1 (en) 2018-04-25
KR20140148420A (ko) 2014-12-31
EP2839010A4 (en) 2015-12-09
CN107266554A (zh) 2017-10-20
CN104364378A (zh) 2015-02-18
WO2013138850A1 (en) 2013-09-26

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTOR TO READ BASTIRAS, STAN; GUIDOLIN, ANGELO; HUNT, BEN; RAISHEED, MUHAMMAD SAIF AND ZAREIE, REZA

NB Applications allowed - extensions of time section 223(2)

Free format text: THE TIME IN WHICH TO GAIN ACCEPTANCE HAS BEEN EXTENDED TO 09 FEB 2016 .

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired