KR20140148420A - 재조합 펩티드의 생산 방법 - Google Patents

재조합 펩티드의 생산 방법 Download PDF

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Publication number
KR20140148420A
KR20140148420A KR1020147029054A KR20147029054A KR20140148420A KR 20140148420 A KR20140148420 A KR 20140148420A KR 1020147029054 A KR1020147029054 A KR 1020147029054A KR 20147029054 A KR20147029054 A KR 20147029054A KR 20140148420 A KR20140148420 A KR 20140148420A
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KR
South Korea
Prior art keywords
peptide
vsdl
leu
fusion polypeptide
glu
Prior art date
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Withdrawn
Application number
KR1020147029054A
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English (en)
Korean (ko)
Inventor
스텐 바스티라스
안젤로 귀돌린
벤 헌트
세이프 래이쉬드
레자 자레이에
Original Assignee
마들렌 파마수티컬스 피티와이 리미티드
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Application filed by 마들렌 파마수티컬스 피티와이 리미티드 filed Critical 마들렌 파마수티컬스 피티와이 리미티드
Publication of KR20140148420A publication Critical patent/KR20140148420A/ko
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020147029054A 2012-03-19 2013-03-19 재조합 펩티드의 생산 방법 Withdrawn KR20140148420A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261612817P 2012-03-19 2012-03-19
US61/612,817 2012-03-19
PCT/AU2013/000273 WO2013138850A1 (en) 2012-03-19 2013-03-19 Method of producing a recombinant peptide

Publications (1)

Publication Number Publication Date
KR20140148420A true KR20140148420A (ko) 2014-12-31

Family

ID=49221695

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147029054A Withdrawn KR20140148420A (ko) 2012-03-19 2013-03-19 재조합 펩티드의 생산 방법

Country Status (8)

Country Link
US (1) US20150315259A1 (enExample)
EP (1) EP2839010B1 (enExample)
JP (1) JP2015510770A (enExample)
KR (1) KR20140148420A (enExample)
CN (2) CN107266554A (enExample)
AU (2) AU2013234860B2 (enExample)
SG (1) SG11201405721VA (enExample)
WO (1) WO2013138850A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8947194B2 (en) 2009-05-26 2015-02-03 Solaredge Technologies Ltd. Theft detection and prevention in a power generation system
EP3773669A4 (en) * 2018-03-29 2022-04-27 Contrafect Corporation ANTIMICROBIAL BACTERIOPHAGE-DERIVED POLYPEPTIDES AND THEIR USE AGAINST GRAM-NEGATIVE BACTERIA
CN113121637B (zh) * 2020-01-15 2022-06-14 鲁南制药集团股份有限公司 一种重组蛋白的分离纯化方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691310A (en) 1987-09-29 1997-11-25 Vesely; David L. Methods of treatment using proANF peptides
GB9716790D0 (en) * 1997-08-07 1997-10-15 Creative Peptides Sweden Ab Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof
ES2263278T3 (es) * 1998-07-10 2006-12-01 Scios Inc. Metodo para producir un peptido con un pl por encima de 8 o por debajo de 5.
WO2000017336A1 (en) * 1998-09-19 2000-03-30 Sang Jun Lee Dna cassette encoding a multimer of a biologically active peptide and a cleavable linker attached thereto and process for preparing the biologically active peptide
US6759510B1 (en) * 2000-06-30 2004-07-06 Becton, Dickinson And Company Peptides for use in culture media
CN1363654A (zh) * 2001-07-19 2002-08-14 上海华谊生物技术有限公司 生产促胰岛素分泌肽glp-1(7-36)的基因工程菌以及生产glp-1(7-36)的方法
ES2343061T3 (es) * 2002-05-24 2010-07-22 Medtronic, Inc. Metodos y constructos de dna para produccion de polipeptidos con rendimiento alto.
DE60331584D1 (de) * 2002-11-26 2010-04-15 Biocon Ltd Modifizierte natriuretic verbindungen, konjugate und ihre verwendungen
WO2005094420A2 (en) * 2004-02-17 2005-10-13 University Of South Florida Materials and methods for treatment of inflammatory and cell proliferation disorders
EP1736480B9 (en) * 2005-06-02 2009-03-04 Polyquant GmbH Artificial protein, method for absolute quantification of proteins and uses thereof
JP5395794B2 (ja) * 2007-09-11 2014-01-22 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのガラニンペプチドの使用
RU2451750C2 (ru) * 2007-09-24 2012-05-27 Общество С Ограниченной Ответственностью "Герофарм" Способ получения рекомбинантного с-пептида проинсулина человека
US8527211B2 (en) * 2008-06-18 2013-09-03 Reza Zareie Method to produce recombinant MBP8298 and other polypeptides by nucleotide structure optimization
JP2013505013A (ja) * 2009-09-18 2013-02-14 セレクシス エス.エー. 強化導入遺伝子発現およびプロセッシングの産物および方法
WO2012019237A1 (en) * 2010-08-12 2012-02-16 Madeleine Pharmaceuticals Pty Ltd Therapeutic method for treating congestive heart failure
WO2012115772A2 (en) * 2011-02-25 2012-08-30 Medtronic, Inc. Therapy for kidney disease and/or heart failure

Also Published As

Publication number Publication date
CN104364378A (zh) 2015-02-18
EP2839010B1 (en) 2018-04-25
AU2016100212A4 (en) 2016-04-14
CN107266554A (zh) 2017-10-20
EP2839010A4 (en) 2015-12-09
EP2839010A1 (en) 2015-02-25
JP2015510770A (ja) 2015-04-13
US20150315259A1 (en) 2015-11-05
WO2013138850A1 (en) 2013-09-26
AU2013234860A1 (en) 2014-10-16
SG11201405721VA (en) 2014-10-30
AU2013234860B2 (en) 2016-01-21

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PA0105 International application

Patent event date: 20141016

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid