AU2011223805B2 - Concentrated protein formulations and uses thereof - Google Patents

Concentrated protein formulations and uses thereof Download PDF

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Publication number
AU2011223805B2
AU2011223805B2 AU2011223805A AU2011223805A AU2011223805B2 AU 2011223805 B2 AU2011223805 B2 AU 2011223805B2 AU 2011223805 A AU2011223805 A AU 2011223805A AU 2011223805 A AU2011223805 A AU 2011223805A AU 2011223805 B2 AU2011223805 B2 AU 2011223805B2
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Australia
Prior art keywords
formulation
amount
salt
antibody
protein
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AU2011223805A
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AU2011223805A1 (en
Inventor
Tracy T. Chen
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Cytodyn Inc
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Cytodyn Inc
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Assigned to CYTODYN INC. reassignment CYTODYN INC. Request for Assignment Assignors: PROGENICS PHARMACEUTICALS, INC.
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Publication of AU2011223805B2 publication Critical patent/AU2011223805B2/en
Priority to AU2016200495A priority Critical patent/AU2016200495B2/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2011223805A 2010-03-01 2011-03-01 Concentrated protein formulations and uses thereof Active AU2011223805B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016200495A AU2016200495B2 (en) 2010-03-01 2016-01-28 Concentrated protein formulations and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33919110P 2010-03-01 2010-03-01
US61/339,191 2010-03-01
PCT/US2011/026647 WO2011109365A2 (en) 2010-03-01 2011-03-01 Concentrated protein formulations and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016200495A Division AU2016200495B2 (en) 2010-03-01 2016-01-28 Concentrated protein formulations and uses thereof

Publications (2)

Publication Number Publication Date
AU2011223805A1 AU2011223805A1 (en) 2012-10-25
AU2011223805B2 true AU2011223805B2 (en) 2015-10-29

Family

ID=44542798

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2011223805A Active AU2011223805B2 (en) 2010-03-01 2011-03-01 Concentrated protein formulations and uses thereof
AU2016200495A Active AU2016200495B2 (en) 2010-03-01 2016-01-28 Concentrated protein formulations and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016200495A Active AU2016200495B2 (en) 2010-03-01 2016-01-28 Concentrated protein formulations and uses thereof

Country Status (15)

Country Link
US (2) US9956165B2 (https=)
EP (1) EP2542221A4 (https=)
JP (2) JP5937523B2 (https=)
KR (1) KR101853981B1 (https=)
CN (2) CN102946861B (https=)
AU (2) AU2011223805B2 (https=)
BR (1) BR112012022223B1 (https=)
CA (1) CA2794929C (https=)
IL (1) IL221748B (https=)
MX (1) MX347504B (https=)
NZ (1) NZ602685A (https=)
RU (1) RU2626512C2 (https=)
SG (1) SG184355A1 (https=)
WO (1) WO2011109365A2 (https=)
ZA (1) ZA201207331B (https=)

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Also Published As

Publication number Publication date
EP2542221A4 (en) 2013-10-23
KR20130010898A (ko) 2013-01-29
CA2794929A1 (en) 2011-09-09
SG184355A1 (en) 2012-11-29
HK1223835A1 (zh) 2017-08-11
MX347504B (es) 2017-04-28
RU2012141655A (ru) 2014-04-10
KR101853981B1 (ko) 2018-05-02
AU2016200495B2 (en) 2017-11-09
WO2011109365A3 (en) 2012-01-05
JP2016193911A (ja) 2016-11-17
BR112012022223A8 (pt) 2017-12-05
ZA201207331B (en) 2014-07-30
CN105521491A (zh) 2016-04-27
MX2012010114A (es) 2013-01-29
AU2011223805A1 (en) 2012-10-25
RU2626512C2 (ru) 2017-07-28
BR112012022223B1 (pt) 2022-08-09
US11571383B2 (en) 2023-02-07
CA2794929C (en) 2018-06-05
CN102946861B (zh) 2016-01-20
JP2013521296A (ja) 2013-06-10
US9956165B2 (en) 2018-05-01
JP5937523B2 (ja) 2016-06-22
BR112012022223A2 (pt) 2016-07-05
WO2011109365A2 (en) 2011-09-09
EP2542221A2 (en) 2013-01-09
JP6229007B2 (ja) 2017-11-08
US20180263898A1 (en) 2018-09-20
US20130216525A1 (en) 2013-08-22
AU2016200495A1 (en) 2016-02-18
CN102946861A (zh) 2013-02-27
IL221748B (en) 2019-09-26
NZ602685A (en) 2014-10-31
CN105521491B (zh) 2020-03-24

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