AU2010326727B2 - Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases - Google Patents

Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases Download PDF

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Publication number
AU2010326727B2
AU2010326727B2 AU2010326727A AU2010326727A AU2010326727B2 AU 2010326727 B2 AU2010326727 B2 AU 2010326727B2 AU 2010326727 A AU2010326727 A AU 2010326727A AU 2010326727 A AU2010326727 A AU 2010326727A AU 2010326727 B2 AU2010326727 B2 AU 2010326727B2
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Australia
Prior art keywords
methyl
amino
sulfonyl
benzamide
chlorophenyl
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AU2010326727A
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AU2010326727A1 (en
Inventor
Milan Bruncko
Yujia Dai
Hong Ding
George A. Doherty
Steven W. Elmore
Todd M. Hansen
Lisa Hasvold
Laura Hexamer
Aaron Kunzer
Robert A. Mantei
William J. Mcclellan
Chang H. Park
Cheol-Min Park
Andrew M. Petros
Xiaohong Song
Andrew J. Souers
Gerard M. Sullivan
Zhi-Fu Tao
Gary T. Wang
Le Wang
Xilu Wang
Michael D. Wendt
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AbbVie Inc
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AbbVie Inc
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
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  • Thiazole And Isothizaole Compounds (AREA)
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AU2010326727A 2009-12-04 2010-06-01 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases Ceased AU2010326727B2 (en)

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Application Number Priority Date Filing Date Title
US12/631,367 2009-12-04
US12/631,367 US20100160322A1 (en) 2008-12-04 2009-12-04 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
PCT/US2010/036844 WO2011068560A1 (en) 2009-12-04 2010-06-01 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases

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AU2010326727A1 AU2010326727A1 (en) 2012-06-07
AU2010326727B2 true AU2010326727B2 (en) 2014-05-29

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