AU2010310589A1 - Modulation of axon degeneration - Google Patents

Modulation of axon degeneration Download PDF

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Publication number
AU2010310589A1
AU2010310589A1 AU2010310589A AU2010310589A AU2010310589A1 AU 2010310589 A1 AU2010310589 A1 AU 2010310589A1 AU 2010310589 A AU2010310589 A AU 2010310589A AU 2010310589 A AU2010310589 A AU 2010310589A AU 2010310589 A1 AU2010310589 A1 AU 2010310589A1
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Australia
Prior art keywords
antibody
dlk
degeneration
neuron
antibodies
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Abandoned
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AU2010310589A
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English (en)
Inventor
Joseph Wesley Lewcock
Christine Pozniak
Arundhati Sengupta-Ghosh
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Genentech Inc
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Genentech Inc
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11025Mitogen-activated protein kinase kinase kinase (2.7.11.25), i.e. MAPKKK or MAP3K
AU2010310589A 2009-10-22 2010-10-21 Modulation of axon degeneration Abandoned AU2010310589A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25419009P 2009-10-22 2009-10-22
US61/254,190 2009-10-22
PCT/US2010/053596 WO2011050192A1 (en) 2009-10-22 2010-10-21 Modulation of axon degeneration

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AU2010310589A1 true AU2010310589A1 (en) 2012-05-10

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AU2010310589A Abandoned AU2010310589A1 (en) 2009-10-22 2010-10-21 Modulation of axon degeneration

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US (3) US20120328609A1 (es)
EP (2) EP2490698A4 (es)
JP (2) JP2013508401A (es)
KR (1) KR20120102642A (es)
CN (2) CN104043126A (es)
AU (1) AU2010310589A1 (es)
BR (1) BR112012009257A2 (es)
CA (1) CA2778483A1 (es)
HK (1) HK1203350A1 (es)
IL (1) IL219232A0 (es)
MX (1) MX2012004638A (es)
RU (1) RU2012120783A (es)
SG (1) SG10201406763WA (es)
WO (1) WO2011050192A1 (es)

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WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
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EP3268373B1 (en) 2015-03-09 2022-04-27 F. Hoffmann-La Roche AG Tricyclic dlk inhibitors and uses thereof
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PL3691620T3 (pl) 2017-10-05 2022-11-21 Fulcrum Therapeutics, Inc. Inhibitory kinazy p38 zmniejszają poziom ekspresji genu dux4 i dalszych genów do leczenia fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
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