AU2009329192A1 - Fused imidazole carboxamides as TRPV3 modulators - Google Patents

Fused imidazole carboxamides as TRPV3 modulators Download PDF

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Publication number
AU2009329192A1
AU2009329192A1 AU2009329192A AU2009329192A AU2009329192A1 AU 2009329192 A1 AU2009329192 A1 AU 2009329192A1 AU 2009329192 A AU2009329192 A AU 2009329192A AU 2009329192 A AU2009329192 A AU 2009329192A AU 2009329192 A1 AU2009329192 A1 AU 2009329192A1
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AU
Australia
Prior art keywords
imidazo
vinyl
thiazole
carboxamide
thiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2009329192A
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English (en)
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AU2009329192A2 (en
Inventor
Sachin Sundarlal Chaudhari
Sachin Vasantrao Dhone
Ashok Bhausaheb Kadam
Suresh Mahadev Kadam
Vidya Ganapati Kattige
Neelima Khairatkar-Josh
Abraham Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ichnos Sciences SA
Original Assignee
Glenmark Pharmaceuticals SA
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Filing date
Publication date
Application filed by Glenmark Pharmaceuticals SA filed Critical Glenmark Pharmaceuticals SA
Publication of AU2009329192A1 publication Critical patent/AU2009329192A1/en
Publication of AU2009329192A2 publication Critical patent/AU2009329192A2/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P27/16—Otologicals
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2009329192A 2008-12-15 2009-12-15 Fused imidazole carboxamides as TRPV3 modulators Abandoned AU2009329192A1 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
IN2610/MUM/2008 2008-12-15
IN2610MU2008 2008-12-15
US14113308P 2008-12-29 2008-12-29
US61/141,133 2008-12-29
IN145/MUM/2009 2009-01-22
IN145MU2009 2009-01-22
US15024809P 2009-02-05 2009-02-05
US61/150,248 2009-02-05
IN1397/MUM/2009 2009-06-10
IN1397MU2009 2009-06-10
US22161509P 2009-06-30 2009-06-30
US61/221,615 2009-06-30
IN1730MU2009 2009-07-29
IN1730/MUM/09 2009-07-29
US23745609P 2009-08-27 2009-08-27
US61/237,456 2009-08-27
PCT/IB2009/007951 WO2010070452A1 (en) 2008-12-15 2009-12-15 Fused imidazole carboxamides as trpv3 modulators

Publications (2)

Publication Number Publication Date
AU2009329192A1 true AU2009329192A1 (en) 2011-12-01
AU2009329192A2 AU2009329192A2 (en) 2012-03-29

Family

ID=42241253

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009329192A Abandoned AU2009329192A1 (en) 2008-12-15 2009-12-15 Fused imidazole carboxamides as TRPV3 modulators

Country Status (12)

Country Link
US (1) US8318928B2 (cg-RX-API-DMAC7.html)
EP (1) EP2367825A1 (cg-RX-API-DMAC7.html)
JP (1) JP2012512151A (cg-RX-API-DMAC7.html)
AR (1) AR076830A1 (cg-RX-API-DMAC7.html)
AU (1) AU2009329192A1 (cg-RX-API-DMAC7.html)
CA (1) CA2746077A1 (cg-RX-API-DMAC7.html)
EA (1) EA201190004A1 (cg-RX-API-DMAC7.html)
GE (1) GEP20146099B (cg-RX-API-DMAC7.html)
MX (1) MX2011006132A (cg-RX-API-DMAC7.html)
NZ (1) NZ595777A (cg-RX-API-DMAC7.html)
TW (1) TW201022283A (cg-RX-API-DMAC7.html)
WO (1) WO2010070452A1 (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010073128A2 (en) * 2008-12-26 2010-07-01 Glenmark Pharmaceuticals, S.A. Fused imidazole derivatives as trpv3 antagonist
JP2013538800A (ja) * 2010-08-10 2013-10-17 アッヴィ・インコーポレイテッド 新規ｔｒｐｖ３モジュレーター
WO2012072512A1 (en) * 2010-11-29 2012-06-07 Glaxo Group Limited N-cyclobutyl-imidazopyridine or -pyrazolopyridine carboxamides as trpv1 antagonists
KR101834362B1 (ko) 2011-03-18 2018-03-05 바이엘 인텔렉쳐 프로퍼티 게엠베하 N-(3-카바모일페닐)-1h-피라졸-5-카복사미드 유도체 및 동물 해충을 구제하기 위한 그의 용도
WO2012129491A1 (en) 2011-03-24 2012-09-27 Abbott Laboratories Trpv3 modulators
US8754101B2 (en) 2011-04-11 2014-06-17 Glaxo Group Limited N-cyclobutyl-imidazopyridine-methylamine as TRPV1 antagonists
CA2853097A1 (en) 2011-10-24 2013-05-02 Abbvie Inc. Novel trpv3 modulators
CN104718213B (zh) * 2012-07-18 2018-02-27 圣母大学 5,5‑杂芳族抗感染化合物
EP3552017B1 (en) * 2016-12-09 2022-02-23 Denali Therapeutics Inc. Compounds useful as ripk1 inhibitors
EP3846793B1 (en) 2018-09-07 2024-01-24 PIC Therapeutics, Inc. Eif4e inhibitors and uses thereof
CN118702672A (zh) 2020-01-29 2024-09-27 卡玛瑞制药有限公司 用于治疗皮肤病症的化合物和组合物
TW202146393A (zh) 2020-03-03 2021-12-16 美商皮克醫療公司 Eif4e抑制劑及其用途
CN118103368A (zh) 2021-08-25 2024-05-28 皮克医疗公司 Eif4e抑制剂及其用途
JP2024532276A (ja) 2021-08-25 2024-09-05 ピク セラピューティクス， インコーポレイテッド ｅＩＦ４Ｅ阻害剤及びその使用

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US5204352A (en) * 1987-09-29 1993-04-20 The United States Of America As Represented By The Secretary Of The Army Compounds exhibiting anti-parasitic activity and a method for their use
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AU2006311883A1 (en) * 2005-11-04 2007-05-18 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
JP2009542608A (ja) 2006-06-29 2009-12-03 アステックス・セラピューティクス・リミテッド 医薬組合せ剤
JP5523829B2 (ja) 2006-06-29 2014-06-18 アステックス、セラピューティックス、リミテッド 複合薬剤
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Publication number Publication date
JP2012512151A (ja) 2012-05-31
EP2367825A1 (en) 2011-09-28
GEP20146099B (en) 2014-05-27
WO2010070452A1 (en) 2010-06-24
AU2009329192A2 (en) 2012-03-29
TW201022283A (en) 2010-06-16
US20100152192A1 (en) 2010-06-17
AR076830A1 (es) 2011-07-13
MX2011006132A (es) 2011-09-01
CA2746077A1 (en) 2010-06-24
NZ595777A (en) 2013-07-26
US8318928B2 (en) 2012-11-27
EA201190004A1 (ru) 2012-11-30

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTORS TO READ CHAUDHARI, SACHIN SUNDARLAL; THOMAS, ABRAHAM; KADAM, ASHOK BHAUSAHEB; DHONE, SACHIN VASANTRAO; KADAM, SURESH MAHADEV; KHAIRATKAR-JOSH, NEELIMA AND KATTIGE, VIDYA GANAPATI

MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period