AU2009261720A2 - Re-useable auto-injector with filling means - Google Patents

Re-useable auto-injector with filling means Download PDF

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Publication number
AU2009261720A2
AU2009261720A2 AU2009261720A AU2009261720A AU2009261720A2 AU 2009261720 A2 AU2009261720 A2 AU 2009261720A2 AU 2009261720 A AU2009261720 A AU 2009261720A AU 2009261720 A AU2009261720 A AU 2009261720A AU 2009261720 A2 AU2009261720 A2 AU 2009261720A2
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AU
Australia
Prior art keywords
chamber
housing
port
stopper
injection device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2009261720A
Other versions
AU2009261720A1 (en
AU2009261720B2 (en
Inventor
Rosemary Louise Burnell
Douglas Ivan Jennings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Cilag GmbH International
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Filing date
Publication date
Application filed by Cilag GmbH International filed Critical Cilag GmbH International
Publication of AU2009261720A1 publication Critical patent/AU2009261720A1/en
Publication of AU2009261720A2 publication Critical patent/AU2009261720A2/en
Application granted granted Critical
Publication of AU2009261720B2 publication Critical patent/AU2009261720B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Basic Packing Technique (AREA)
  • Fuel-Injection Apparatus (AREA)
  • Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Description

WO 2009/153545 PCT/GB2009/001453 RE-USABLE AUTO-INJECTOR WITH FILLING MEANS Field of the Invention 5 This invention relates to an injection device, for example, a re-useable auto-injector into which a drug may be transferred from a vial prior to subcutaneous injection into a patient. Background of the Invention 10 The use of automatic injection devices (commonly known as auto-injectors) to deliver a medicament to a patient has provided many benefits over manual syringes. In particular, auto-injectors have helped to relieve the burden on hospital staff to deliver a drug to a patient because patients are able to use the devices on themselves reliably and safely and 15 in their own home. Known auto-injectors are described in WO 95/35126 and EP-A-0 516 473. These and similar auto-injectors are typically provided primed (i.e. pre-sprung) and ready to be used for injecting a patient. For these reasons, it is difficult to insert a drug into the auto 20 injector and, as a consequence, manufacturers of such auto-injectors have typically provided a pre-filled syringe for use in the auto-injector, or a complete auto-injector unit which is pre-filled with a particular drug. This requires a more complicated and expensive manufacturing process than would be 25 otherwise required for an auto-injector because manufacturers must also obtain and provide the drugs and maintain the facilities for storing and handling them. Furthermore, the manufacturer must operate separate production lines for each drug which is required. 30 Drugs for medical use are often manufactured and distributed in standard vials. In this way, drugs may be supplied in bulk conveniently and relatively cheaply, regardless of the way in which the drug is finally used. - 1- WO 2009/153545 PCT/GB2009/001453 A significant cost-saving could be made in providing an auto-injector device which is capable of drawing a drug from a standard vial rather than relying on a pre-filled syringe. Not only would such a device benefit the manufacturers, who would no longer have to provide bespoke drug-filled devices, but also hospitals, which would enjoy a simplified 5 inventory system and could make use of the standard vials which are used on a regular basis, and patients, who could be provided with a supply of vials for self administration. In addition, the use of vials permits the possibility of reusing a greater proportion of an auto-injector device. Typically, auto-injectors are provided in two subassemblies. The 10 first subassembly comprises the operating mechanisms and all other reusable components and the second subassembly contains the injection components that must be replaced each time the device is used. A major factor in the cost of the second subassembly is the provision of a chamber 15 which is pre-filled with a drug to be injected. As explained above, providing a range of syringes is an expensive and time-consuming aspect of the manufacturing process of an auto-injector. The use of standard vials would enable this cost to be reduced. Summary of the Invention 20 The present invention aims to solve the aforementioned problems. Accordingly, an injection device comprises a housing; a chamber disposed within the housing, the chamber having proximal and distal ends, an inner surface and an exit aperture; a stopper movably disposed within the chamber, and having an outer surface substantially in 25 contact with the inner surface about its perimeter; and a port adapted to receive a container containing a fluid. The stopper is fixed with respect to the housing and movement of the port causes movement of the exit aperture in relation to the stopper. Providing an injection device, such as an auto-injector, having a chamber into which a 30 fluid may be transferred from a separate container provides at least two benefits over the prior art. Firstly, manufacturers of auto-injector devices need no longer manufacture a range of pre-filled syringes to be inserted into a reusable sub-assembly. Rather, the -2- WO 2009/153545 PCT/GB2009/001453 manufacturer may provide instead a single type of sub-assembly in accordance with the present invention into which any variety of drug may be transferred immediately prior to injection. The single type of sub-assembly may be manufactured in bulk, thereby reducing the manufacturing costs. 5 This advantage leads on to a second benefit whereby the invention may be used in conjunction with any type of container from which a drug may be transferred into the chamber. In particular the invention may be used with standard vials. 10 Furthermore, the invention allows a greater proportion of the needle assembly to be reused. Whereas known auto-injector systems require pre-filled syringes, the capability of transferring fluid into a chamber within the needle device permits greater scope for reusability. 15 The volume of the chamber into which the fluid is transferred is defined by the space between the stopper and the exit aperture. Consequently, the volume is decreased as the stopper is moved toward the exit aperture and increased as the stopper is moved away from the exit aperture. An increase in volume causes an initial decrease in pressure in the chamber which thereby draws the fluid into the chamber. 20 The port may be configured to bring the container into fluid engagement with the exit aperture when the exit aperture is adjacent the stopper. In this position, the volume of the chamber is at or substantially at its lowest. Preferably, engagement between the container and the exit aperture forms a fluid conduit for transferring fluid from the 25 container to the chamber. In accordance with this embodiment, as the volume of the chamber is increased (for example, by moving the exit aperture away from the stopper) fluid from the container is transferred into the chamber. In some embodiments, a biasing element is coupled to the port and configured to bias the 30 port such that the exit aperture is biased away from the stopper. Starting from the position mentioned above (i.e. wherein the exit aperture is adjacent the stopper and the container is in fluid engagement with the exit aperture), the action of the biasing element -3- WO 2009/153545 PCT/GB2009/001453 will cause the fluid to be transferred into the chamber without the need for external intervention. Optionally the biasing element is a spring, but other elements which perform a similar function are also envisaged. 5 In other embodiments, the injection device comprises a discharge nozzle in fluid communication with the exit aperture. Typically, containers suitable for use with the device comprise a cap made from rubber or foil, for example. In such cases, the discharge nozzle may be configured to pierce the cap to form a fluid conduit for transferring fluid from the container to the chamber. 10 Brief Description of the Drawings The invention will now be described by way of example with reference to the accompanying drawings, in which: 15 Figure 1 is a side view of a first sub-assembly of an injection device; Figure 2 is a side view of the first sub-assembly wherein the cap has been removed; 20 Figure 3 is a side view of a container being engaged with the first sub-assembly; Figure 4 is a side view of the first sub-assembly in the fully retracted position; Figure 5 is a side view of the first sub-assembly in the fully extended position; 25 Figure 6 is a side view of the container being removed from the first sub-assembly; Figure 7 is a side view of the first sub-assembly being engaged with a second sub assembly; and 30 Figure 8 is a side view of an injection device comprised of the first and second sub assemblies. -4- WO 2009/153545 PCT/GB2009/001453 Detailed Description of the Drawings Figures 1 to 4 illustrate a first sub-assembly 110 suitable for use in an auto-injector according to the present invention. 5 The first sub-assembly 110 comprises a housing 111 and a chamber 112 disposed within the housing. The housing 111 has proximal 111 a and distal 111 b ends. The chamber 112 has proximal and distal ends, corresponding to the proximal and distal ends of the housing, and an inner surface. Adjacent the proximal end of the chamber there is 10 provided a stopper 113. The stopper 113 is moveably disposed within the chamber 112 and has an outer surface. The outer surface of the stopper 113 is substantially in contact with the inner surface of the chamber 112 about its perimeter. At the distal end of the chamber 112 there is provided an exit aperture 114. An injection 15 needle 115 is provided in fluid connection with the exit aperture 114. The injection needle 115 is suitable for piercing the skin of a patient and delivering a drug subcutaneously. The needle 115 is also suitable for piercing a foil or rubber cap as might be provided on a vial. 20 The first sub-assembly 110 comprises a removable cap 116 including a sheath 117 disposed over the needle 115. The sheath 117 protects the needle and provides a substantially fluid tight seal over the tip of the needle, to prevent unwanted fluid ingress or egress. 25 Figure 2 illustrates the first sub-assembly of Figure 1 wherein the cap 116 has been removed from the first sub-assembly 110. In removing the cap 116, the sheath 117 has been removed from the needle 115. As can be seen in this figure, the first sub-assembly comprises a port 118 (or sleeve). In this configuration, the port 118 surrounds the needle to prevent damage to the needle or accidental contact between the needle and the user. 30 The port 118 is moveable in relation to the housing 111 but is coupled to the chamber 112 such that movement of the port 118 causes a corresponding movement of the -5- WO 2009/153545 PCT/GB2009/001453 chamber 112 and the exit aperture 114, relative to the housing 111. In Figure 2, the port 118, and hence the chamber 112, are in a fully extended position. The sub-assembly 110 comprises a biasing element 121 which acts on the port 118 to 5 bias it away from the housing 111. In so doing, the biasing element 121 biases the exit aperture 114 of the chamber 112, which is moveable in relation to the housing 111, away from the stopper 113 which, at this point in the operation of the auto-injector (i.e. prior to activation of the auto-injector; specifically prior to advancement of the needle assembly out of the housing) is fixed in relation to the housing. As shown in Figure 2, 10 the stopper 113 is coupled to a support rod 124 via a support block 126. The support rod is attached to the housing 111. The stopper 113 abuts the support block 126 and remains stationary with respect to the support rod 124 when the port 118 and the chamber 112 are advanced toward the proximal end 111 a of the housing (described in detail below). The chamber is configured to slide over the support rod 124 and support block 126. 15 At its distal end 111a, the housing 111 comprising a first detent 122a. A second detent 122b, provided on the port 118, interfaces with the first detent 122a when the port 118 and the chamber 112 are in a fully extended position. The detents 122 prevent the port 118 from being extended beyond this position by action of the biasing element 121. 20 As shown in Figure 3, the port 118 is adapted to receive a container 119 containing a fluid, for example a pharmaceutical product. Figure 3 depicts a vial, but other containers may be used. The container 119 includes a cap 120 at one end. As illustrated, the end of the container having the cap 120 is inserted into the port 118 whilst the port is in an 25 extended position. The port 118 is sized and shaped to accept the container 119 and hold it within the port 118 without the need for any additional locking mechanism. Of course, locking means may be provided to give better securement. The available volume of the chamber 112 into which a fluid may be transferred depends 30 on the distance between the stopper 113 and the exit aperture 114. In Figures 1 to 3, the available volume of the chamber 112 is substantially at its greatest. However, in this state, prior to the engagement of the container 119, the chamber 112 is empty. The -6- WO 2009/153545 PCT/GB2009/001453 process of transferring fluid from the container 119 to the chamber 112 will be described with reference to Figures 4 and 5. As a user inserts the container 119 into the port 118, the container is retained inside the 5 port by a flange (not shown) provided around the inner surface of the port 118. The flange occupies a recess in the container 119, thereby securing the container within the port 118. As the container 119 is advanced further, the port 118 and the chamber 112 are driven 10 towards the proximal end 111a of the housing 111. As the chamber 112 is moved towards the proximal end 111 a of the housing, the exit aperture 114 is moved toward the stopper 113. The available volume of the chamber 112 decreases accordingly. Figure 4 shows the first sub-assembly 110 when the port 118 and the chamber 112 are in 15 a fully retracted position. As illustrated, in the fully retracted position, the stopper 113 is immediately adjacent the exit aperture 114. In this configuration, the available volume of the chamber 112 is substantially at its lowest. As the user engages the container 119 with the port 118, the injection needle 115 pierces 20 the cap 120 and provides a fluid conduit between the container 119 and the chamber 112. The fluid conduit begins at the container 119, passes through the injection needle 115 and the exit aperture 114 and ends at the chamber 112. In Figure 4, the fluid is contained within the container 119. As the user releases the 25 container 119, the biasing element 121 forces the port 118 away from the housing 111 and, accordingly, forces the exit aperture 114 away from the stopper 113. The container 119 remains secured within the port 118 and engaged with the needle 115 which is moved along with the exit aperture 114. Thus, the fluid conduit is preserved. 30 As the exit aperture 114 moves away from the stopper 113, the available volume of the chamber 112 increases. The increase in volume of the chamber 112 causes a reduction in chamber pressure and the pressure difference between the vial and the chamber causes -7-- WO 2009/153545 PCT/GB2009/001453 fluid to be drawn from the container 119 along the fluid conduit into the chamber 112. The further the exit aperture 114 moves away from the stopper 113, the more fluid is drawn into the chamber 112. 5 Figure 5 illustrates the sub-assembly 110 after the biasing element 121 has forced the port 118 and the chamber 112 into the fully extended position. As before, the detents 122a,b on the housing 111 and the port 118 prevent the port 118 from being over extended. As shown, the fluid has been completely transferred from the container 119 to the chamber 112. The available volume of the chamber 112, between the stopper 113 10 and the exit aperture 114, is now filled with the fluid. As it is now spent, the empty container 119 may be removed from the first sub-assembly 110 and discarded. Figure 6 illustrates the first sub-assembly 110 which has been primed (i.e. filled with the fluid) and is ready to be used. 15 To administer the fluid, the first sub-assembly 110 is engaged with a second sub assembly 210. As illustrated in Figure 7, the second sub-assembly comprises a housing 211 and a drive mechanism 212. The housing has proximal 211 a and distal 211 b ends and a cap 213 located at the proximal end 21 1b. The cap includes a lip 215 which is 20 engageable with the housing 111 of the first sub-assembly 110. A slot 214 is provided in the second sub-assembly 210. Once the first sub-assembly 110 has been primed, the distal end 211 b of the housing 211 of the second sub-assembly 210 is inserted into the proximal end 111a of the housing 25 111 of the first sub-assembly 110. The chamber 112 fits within the slot 214 and is coupled to the driving mechanism 212. The second sub-assembly 210 is secured to the first sub-assembly 110 by rotating the cap 213 which engages the lip 215 with the housing 111 of the first sub-assembly 110. 30 Figure 8 illustrates an injection device 300 which has been primed and is ready to use. Activation of a firing mechanism of the injection device 300 actuates the driving mechanism 212 which exposes the needle 115 outside of the injection device 300 to -8- WO 2009/153545 PCT/GB2009/001453 pierce the skin of a patient and drives the stopper 113 through the chamber 112 to inject the patient with the fluid. The drive mechanism 212 subsequently retracts the needle 115 so that it is wholly within the injection device 300. 5 Once the fluid has been injected, the second sub-assembly 210 may be disassembled from the first sub-assembly 110 and reused. The first sub-assembly 110 may be discarded and a new first sub-assembly provided for subsequent injections, or may be sterilised for reuse. 10 It will be appreciated that modifications may be made to the embodiment described without departing from the scope of the invention, as defined in the appended claims. -9-

Claims (11)

1. An injection device having a first sub-assembly comprising: a housing; 5 a chamber disposed within the housing and having proximal and distal ends, an inner surface and an exit aperture; a stopper movably disposed within the chamber and having an outer surface substantially in contact with the inner surface about its perimeter; and a port adapted to receive a container containing a fluid; 10 wherein the stopper is fixed with respect to the housing and movement of the port causes movement of the exit aperture in relation to the stopper.
2. The injection device of claim 1, wherein the port is configured to bring said container into fluid engagement with the exit aperture when the exit aperture is adjacent 15 the stopper.
3. The injection device of claim I or claim 2, further comprising: a biasing element coupled to the port and configured to bias the port such that the exit aperture is biased away from the stopper. 20
4. The injection device of claim 2 or claim 3, wherein engagement between the container and the exit aperture forms a fluid conduit for transferring fluid from the container to the chamber. 25
5. The injection device of any preceding claim, further comprising an injection needle in fluid communication with the exit aperture.
6. The injection device of claim 5, wherein the container comprises a cap, and wherein the injection needle is configured to pierce the cap to form a fluid conduit for 30 transferring fluid from the container to the chamber. -10- 7365851) .doc
7. The injection device of any preceding claim, further comprising a second sub assembly comprising: a releasable drive mechanism configured to be driven against the stopper upon activation of the drive mechanism. 5
8. The injection device of claim 7, when dependent on claim 5 or claim 6, wherein the releasable drive mechanism is, upon activation, adapted to: (a) move the chamber and the injection needle from a retracted position in which the needle is wholly inside the housing to an extended position in which the needle is at 10 least partially outside the housing; and (b) subsequently move the stopper within the chamber toward the exit aperture to expel fluid out of the injection needle.
9. The injection device of claim 8, further comprising a retraction mechanism 15 adapted to retract the injection needle into the housing after the fluid has been expelled.
10. The injection device of any one of claims 7 to 9, wherein: the first sub-assembly is detachable from the second sub-assembly; and the second sub-assembly is reusable. 20
11. A method of priming an injection device having a housing, comprising: inserting a container into a port on the injection device, the port being moveable with respect to the housing, the injection device comprising a chamber having an exit aperture and a stopper movably disposed within the chamber, the stopper being fixed 25 with respect to the housing such that movement of the port causes movement of the exit aperture relative to the stopper; moving the port into the housing; and moving the port out of the housing such that fluid is drawn into the chamber from the container. -Il 1-
AU2009261720A 2008-06-19 2009-06-10 Re-useable auto-injector with filling means Ceased AU2009261720B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0811345.8A GB2461085B (en) 2008-06-19 2008-06-19 Injection device
GB0811345.8 2008-06-19
PCT/GB2009/001453 WO2009153545A1 (en) 2008-06-19 2009-06-10 Re-useable auto-injector with filling means

Publications (3)

Publication Number Publication Date
AU2009261720A1 AU2009261720A1 (en) 2009-12-23
AU2009261720A2 true AU2009261720A2 (en) 2011-02-10
AU2009261720B2 AU2009261720B2 (en) 2013-11-14

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Application Number Title Priority Date Filing Date
AU2009261720A Ceased AU2009261720B2 (en) 2008-06-19 2009-06-10 Re-useable auto-injector with filling means

Country Status (18)

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US (1) US9682194B2 (en)
EP (1) EP2326366B1 (en)
JP (1) JP5524197B2 (en)
KR (1) KR101705012B1 (en)
CN (1) CN102065935B (en)
AU (1) AU2009261720B2 (en)
BR (1) BRPI0914979A2 (en)
CA (1) CA2729135C (en)
EA (1) EA020309B1 (en)
ES (1) ES2797481T3 (en)
GB (1) GB2461085B (en)
IL (1) IL209783A (en)
MX (1) MX2010014014A (en)
NO (1) NO20110087A1 (en)
NZ (1) NZ590615A (en)
UA (1) UA100745C2 (en)
WO (1) WO2009153545A1 (en)
ZA (1) ZA201100495B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414775B (en) 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
ES2340936T3 (en) 2005-08-30 2010-06-11 Cilag Gmbh International NEEDLE ASSEMBLY FOR A PRE-LOADED SYRINGE SYSTEM.
US20110098656A1 (en) * 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
GB2438590B (en) * 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2461086B (en) * 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461084B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
GB2461087B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461089B (en) 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
CA2803154A1 (en) * 2010-06-28 2012-01-05 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2716317A1 (en) 2012-10-04 2014-04-09 Sanofi-Aventis Deutschland GmbH Medicament delivery device with trigger button
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
KR102593071B1 (en) * 2015-05-08 2023-10-23 프레세니우스 카비 에이비 Connector for a medical container
WO2017086867A1 (en) * 2015-11-19 2017-05-26 Hemcheck Sweden Aktiebolag A protective device for and method of reducing the risk to medical personnel of accidentally puncturing themselves on a hypodermic needle
EP3146856B1 (en) * 2016-09-06 2022-03-16 Fontem Holdings 1 B.V. Syringe refiller for an electronic smoking device
CN110382024A (en) * 2016-12-06 2019-10-25 注射科技股份有限公司 For with the method and apparatus of retractable needles filling syringe
EP3746155A4 (en) * 2018-02-02 2021-10-27 Becton, Dickinson and Company Syringe assembly

Family Cites Families (566)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE356704C (en) 1918-03-15 1922-07-27 Edmondo Luswergh Dr syringe
US1845036A (en) 1930-03-12 1932-02-16 Herbert H Busher Hypodermic syringe
GB412054A (en) 1932-08-04 1934-06-21 Loewe Opta Gmbh Improvements in wireless receivers
US2019382A (en) 1935-02-19 1935-10-29 Art Metal Works Inc Torch
US2147616A (en) 1937-07-09 1939-02-14 Elmer J Chaput Dental and medical hypodermic syringe
US2295849A (en) 1940-10-25 1942-09-15 Gustave L Kayden Attachment for hypodermic syringes
US2531267A (en) 1947-10-16 1950-11-21 Harnisch Fritz Hypodermic syringe operating device
FR1078911A (en) 1949-08-17 1954-11-24 Automatic hypodermic syringe and its ampoule
FR1014881A (en) 1950-03-21 1952-08-25 Automatic device for parenteral injections
US2764977A (en) 1951-05-24 1956-10-02 Becton Dickinson Co Hypodermic injection mechanism
US2854975A (en) 1952-08-07 1958-10-07 Miljam Instr Corp Hypodermic syringe
FR1169935A (en) 1957-03-22 1959-01-07 S E D A T Soc D Etudes Et D Ap Improvements to auto-injectable ampoules
US2828742A (en) 1957-05-02 1958-04-01 American Home Prod Cartridge-needle unit
GB909898A (en) 1958-04-17 1962-11-07 Donald Travers Lewis Improvements in or relating to a device for automatically effecting injections with a hypodermic syringe
US3076455A (en) 1958-12-19 1963-02-05 Robert K Mcconnaughey Holder for hypodermic syringe cartridges
GB964585A (en) 1960-03-23
US3329146A (en) 1963-10-02 1967-07-04 Baxter Laboratories Inc Needle container
US3320955A (en) * 1963-10-09 1967-05-23 Sarnoff Stanley Jay Automatic injection hypodermic syringe
FR1538565A (en) 1967-07-26 1968-09-06 Automatic hypodermic syringe
US3543603A (en) 1968-01-10 1970-12-01 Rex Chainbelt Inc Automatic quick release mechanism
NO124977B (en) 1968-08-09 1972-07-03 Philips Nv
FR2040830A5 (en) 1969-04-15 1971-01-22 Ben Moura Pierre
BE755224A (en) 1969-08-25 1971-02-24 Philips Nv INJECTION SYRINGE
DE6944378U (en) 1969-11-14 1970-04-16 Georg A Henke Gmbh Fa SELF-INJECTING DEVICE
US3702608A (en) 1970-12-15 1972-11-14 Robert C Tibbs Painless injection device with powered plunger
BE795162A (en) 1972-02-10 1973-08-08 Philips Nv INJEKTIE-INRICHTING
US3797488A (en) 1972-07-10 1974-03-19 Ampoules Inc Ampoule applicator with one-way clutch
US3880163A (en) 1973-10-26 1975-04-29 Jack H Ritterskamp Medicinal syringe actuating device
NL172403C (en) * 1974-04-08 1983-09-01 Duphar Int Res SYRINGE WITH A CARTRIDGE AND A CARTRIDGE, WITH THE CARTRIDGE CONTAINING PATTERN LOCKERS, AND THE CARTRIDGE CONTAINER FOR AN INJECTION SYRINGE.
GB1514725A (en) 1975-05-23 1978-06-21 Everett Med Prod Ltd Hyperdermic needle assembly
GB1583157A (en) * 1976-05-07 1981-01-21 Kenova Ab Syringes
US4165739A (en) 1976-09-02 1979-08-28 Doherty Norman R Inoculator
US4180070A (en) 1977-08-29 1979-12-25 Abbott Laboratories Disposable double vial syringe
US4222380A (en) * 1977-12-02 1980-09-16 Olympus Optical Co., Ltd. Celiac injector
DE2812729A1 (en) 1978-03-23 1979-09-27 Michael Becker INJECTION DEVICE FOR INTRAMUSCULAR INJECTION, PRESENTLY OF INSULIN
US4185628A (en) * 1978-05-31 1980-01-29 Kopfer Rudolph J Compartmental syringe
US4194505A (en) 1978-09-15 1980-03-25 Vac-O-Cast, Inc. Containerized hypodermic module
US4237882A (en) 1979-09-27 1980-12-09 Sherwood Medical Industries Inc. Needle sheath
DE8006721U1 (en) * 1980-03-12 1981-09-03 Becker, Michael, 5020 Frechen INJECTION DEVICE FOR INTRAMUSCULAR INJECTION OF A MEDICINE, IN PARTICULAR INSULIN
US4299238A (en) 1980-06-24 1981-11-10 Baidwan Balinderjeet S Vented piston and push-rod subassembly for use in a syringe barrel
FR2506161A1 (en) 1981-05-20 1982-11-26 Alsetex Armement Self:injection syringe with compartments for specific liquids - is spring:loaded first to penetrate patient then inject liq.(s), is automatic
US4403989A (en) * 1981-09-14 1983-09-13 Syntex (U.S.A.) Inc. Injection device
US4407283A (en) 1981-10-19 1983-10-04 Dale C. Grier Self-injecting syringe
US4394863A (en) 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4378015A (en) 1981-12-21 1983-03-29 Wardlaw Stephen C Automatic injecting syringe
US4425120A (en) 1982-04-15 1984-01-10 Sampson Norma A Shielded hypodermic syringe
US4430080A (en) 1982-06-09 1984-02-07 Becton, Dickinson And Company Syringe assembly with snap-fit components
US4430082A (en) * 1982-06-25 1984-02-07 Hoffmann-La Roche Inc. Hypodermic syringe assembly
US4500310A (en) 1982-12-20 1985-02-19 Becton, Dickinson And Company Variable sealing pressure plunger rod assembly
US4676530A (en) * 1983-04-07 1987-06-30 Warner-Lambert Company Coupling assembly for use in fluid flow systems
US4521237A (en) 1983-05-23 1985-06-04 Kahle Engineering Co. Glass dose syringe
US4561856A (en) 1983-08-18 1985-12-31 Cochran Ulrich D Infusion pump
DE3342407A1 (en) 1983-11-24 1985-06-05 Erwin 6950 Mosbach Maurer INJECTION DEVICE
AU573369B2 (en) * 1984-07-31 1988-06-02 N.J. Phillips Pty. Limited A rumen injector
NZ212899A (en) 1984-07-31 1987-10-30 Phillips Pty Ltd N J Piston operated adjustable volume dose injector for animals
DD229932A1 (en) 1984-12-03 1985-11-20 Nordhausen Veb Fernmeldewerk INJECTION PISTOL, ESPECIALLY FOR METAL-GLASS SPRAYING
DD234613A1 (en) 1985-02-14 1986-04-09 Karl Marx Stadt Tech Hochschul DEVICE WITH DAY MEDICATION DEPOT FOR PAIN-RELIEF INJECTION
US4627835A (en) 1985-03-11 1986-12-09 Strato Medical Corporation Tubing assembly for infusion device
US4636201A (en) * 1985-11-01 1987-01-13 American Hospital Supply Corporation Hypodermic syringe having a protective sheath cover
US4636198A (en) 1985-11-18 1987-01-13 Mallinckrodt, Inc. Power syringe with volume reducing adapter
US4639250A (en) * 1986-02-20 1987-01-27 Becton, Dickinson And Company Syringe barrel and hypodermic needle assembly
US4735311A (en) 1986-04-09 1988-04-05 The West Company Needle shield assembly
US4744786A (en) 1986-06-17 1988-05-17 Cordis Corporation Infusion pump
FR2600258A1 (en) 1986-06-18 1987-12-24 Hazon Bernard PUSH-SYRINGE DEVICE FOR AUTOMATIC PARENTERAL INJECTION WITH SERVICING AND PROGRAMMING
DE3645245C2 (en) * 1986-11-14 1994-01-27 Haselmeier Wilhelm Fa Injection appliance
CA1285441C (en) 1987-03-17 1991-07-02 Roy D. Mcnaughton Mcnaughton syringe shield type b
DE3715258C2 (en) 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injection device
FR2629706B1 (en) 1988-04-11 1992-05-22 Accaries Claude LIQUID INJECTION APPARATUS, PARTICULARLY FOR USE IN DENTAL CARE
WO1988010129A1 (en) 1987-06-25 1988-12-29 Nova Medical Pty. Limited Slow delivery injection device
US5364369A (en) 1987-07-08 1994-11-15 Reynolds David L Syringe
US4787891A (en) 1987-07-13 1988-11-29 Paul Levin Syringe holder and applicator
US4874384A (en) 1987-07-13 1989-10-17 International Medical Innovators, Inc. Needle safety guard
AU3071689A (en) 1988-03-01 1989-09-07 Ryan Medical, Inc. Safety needled medical devices capable of one-handed manipulation
JPH0534669Y2 (en) * 1988-03-16 1993-09-02
GB8809115D0 (en) 1988-04-18 1988-05-18 Turner R C Syringes
US5156599A (en) 1988-06-28 1992-10-20 Sherwood Medical Company Syringe and sliding locking needle shield
US5026349A (en) 1988-10-05 1991-06-25 Autoject Systems Inc. Liquid medicament injector system
FR2638359A1 (en) 1988-11-03 1990-05-04 Tino Dalto SYRINGE GUIDE WITH ADJUSTMENT OF DEPTH DEPTH OF NEEDLE IN SKIN
US5263933A (en) 1988-12-14 1993-11-23 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
JPH02185261A (en) 1988-12-20 1990-07-19 Candera Estourci Miracle Syringe
US4988339A (en) 1988-12-30 1991-01-29 Vadher Dinesh L Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures
US4929232A (en) * 1989-03-30 1990-05-29 Becton, Dickinson And Company Syringe having tamper evidence features
JPH02299660A (en) 1989-05-15 1990-12-11 Yokoshima Rika Sangyo Kk Method for filling liquid medicine into syringe serving also as container
US4969870A (en) 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
US6096005A (en) 1989-07-11 2000-08-01 Mdc Investment Holdings, Inc. Retractable needle medical devices
DE3929777A1 (en) 1989-09-07 1991-03-14 Dieter Dr Lucas INJECTION SYRINGE
US5112119A (en) * 1989-10-27 1992-05-12 International Business Machines Corp. Support structure for devices in a computer apparatus
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
GB8926825D0 (en) 1989-11-28 1990-01-17 Glaxo Group Ltd Device
CN2059579U (en) 1989-12-22 1990-07-25 国营建安机械厂 Device for inserting needle into vein for beast
CA2071906C (en) 1990-02-12 1999-12-28 Diane Lynn Furio Odor controlling compositions and articles
US5057079A (en) 1990-04-03 1991-10-15 Roland Tiemann Sheathing device for after use protection from a syringe needle
SG42825A1 (en) 1990-07-04 1997-10-17 Maxwell Edmund Whisson Improved parenteral device
FR2665079A1 (en) 1990-07-27 1992-01-31 Conception Fabr Innovations Me Syringe with disposable needle
GB9100819D0 (en) 1991-01-15 1991-02-27 Medimech Int Ltd Subcutaneous injector
US5098400A (en) * 1991-02-14 1992-03-24 Sherwood Medical Company Needle shield
US5271744A (en) 1991-04-29 1993-12-21 George C. Kramer System and method for rapid vascular drug delivery
US5451210A (en) 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
US5176643A (en) 1991-04-29 1993-01-05 George C. Kramer System and method for rapid vascular drug delivery
US5868711A (en) 1991-04-29 1999-02-09 Board Of Regents, The University Of Texas System Implantable intraosseous device for rapid vascular access
US5405362A (en) 1991-04-29 1995-04-11 The Board Of Regents For The University Of Texas System Interactive external defibrillation and drug injection system
US5147325A (en) * 1991-05-03 1992-09-15 Sherwood Medical Company Rigid needle shield
GB9111600D0 (en) 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
EP0518416A1 (en) 1991-06-13 1992-12-16 Duphar International Research B.V Injection device
GB9115765D0 (en) 1991-07-22 1991-09-04 Britt Adrian J Bacterial enzyme for cocaine detection
DE59202070D1 (en) * 1991-07-24 1995-06-08 Medico Dev Investment Co Injector.
DE69229180T2 (en) 1991-11-12 1999-10-14 Urs. A. Ramel LANCETTE DEVICE
GB9200219D0 (en) 1992-01-07 1992-02-26 Medimech Int Ltd Automatic injectors
US5242416A (en) * 1992-01-09 1993-09-07 Hutson Clifford L Shield assembly for needle syringes
EP0562671B1 (en) 1992-03-27 1996-05-29 Duphar International Research B.V Automatic injector
ZA932947B (en) 1992-04-28 1993-10-27 Schering Plough Healthcare Applicator for semisolid medications
US6290683B1 (en) * 1992-04-29 2001-09-18 Mali-Tech Ltd. Skin piercing needle assembly
IL105706A (en) 1992-05-15 1996-10-16 Safe T Ltd Hollow needle applicator
US5250026A (en) 1992-05-27 1993-10-05 Destron/Idi, Inc. Adjustable precision transponder injector
US5267962A (en) 1992-06-10 1993-12-07 Jenson Robert W Disposable hypodermic syringe with needle safe feature
EP0585626A1 (en) 1992-08-14 1994-03-09 Hoechst Aktiengesellschaft Laminated mineral fibre mat
WO1994004207A1 (en) 1992-08-17 1994-03-03 Allard Edward F Method and apparatus for a retracting needle
US5267963A (en) 1992-08-21 1993-12-07 Nicholas Bachynsky Medication injection device
EP0658090B1 (en) 1992-09-01 1998-11-04 Edwin L. Adair Sterilizable endoscope with separable disposable tube assembly
US5190526A (en) 1992-09-18 1993-03-02 Murray Kenneth W Hypodermic safety syringe with retracting needle system
AU5293393A (en) 1992-09-28 1994-04-26 Equidyne Systems, Incorporated Hypodermic jet injector
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
DE69319753T2 (en) 1992-11-19 1999-04-15 Tebro S.A., Luxembourg AUTOMATIC INJECTION DEVICE FOR PRE-FILLED SYRINGES
IT1256577B (en) 1992-12-11 1995-12-11 Ermanno Greco DEVICE PREPARED FOR THE AUTOMATIC ADMINISTRATION OF A DRUG VIA INTRADERMIC.
US5370621A (en) 1992-12-14 1994-12-06 Mallinckrodt Medical, Inc. Insert device for facilitating limited aspiration of a delivery apparatus
US5569191A (en) 1992-12-15 1996-10-29 Meyer; Gabriel Device for preparing a medicinal substance solution, suspension or emulsion
US5250037A (en) 1992-12-18 1993-10-05 Becton, Dickinson And Company Syringe having needle isolation features
DE69427226T2 (en) 1993-03-24 2001-08-30 Owen Mumford Ltd., Woodstock DEVICE FOR INJECTION
US5540666A (en) * 1993-03-31 1996-07-30 Immuno Aktiengesellschaft Cannula shield and injection syringe system
US5330081A (en) * 1993-04-08 1994-07-19 Impact Products, Inc. Measuring dosage dispenser
JP3296025B2 (en) 1993-05-21 2002-06-24 ニプロ株式会社 Drug-filled syringe
US5368577A (en) 1993-05-24 1994-11-29 Biocon International Corporation Needle stick prevention device
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5358489A (en) 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5425715A (en) 1993-08-05 1995-06-20 Survival Technology, Inc. Reloadable injector
JP3199524B2 (en) * 1993-08-06 2001-08-20 日本メジフィジックス株式会社 Luer needle unit and syringe
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
EP0717611B1 (en) 1993-09-07 1998-08-12 Debiotech S.A. Syringe device for mixing two compounds
FR2717086A1 (en) 1994-03-11 1995-09-15 Debiotech Syringe system for mixing two compounds
US5372586A (en) 1993-10-20 1994-12-13 Habley Medical Technology Corp. Telescoping pharmaceutical storage and mixing syringe
JPH07120326A (en) * 1993-10-22 1995-05-12 Komatsu Ltd Wavelength detector
JPH07116224A (en) 1993-10-28 1995-05-09 Arute:Kk Syringe
CA2135706C (en) 1993-11-15 1999-06-15 Walter E. Cover Retractable-needle cannula insertion set with refinements to better control leakage, retraction speed, and reuse
US5330430A (en) 1993-12-06 1994-07-19 Sullivan Robert J Retractable syringe applicator
US5356395A (en) 1993-12-14 1994-10-18 Chen Shih Shuan Safety syringe shield
FR2715071B1 (en) 1994-01-17 1996-03-01 Aguettant Lab Automatic drug injector.
JPH07213610A (en) 1994-01-28 1995-08-15 Shirota Denki Rozai Kk Dental electric injector
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
US5514097A (en) 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
WO1995024176A1 (en) * 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
FR2718357B1 (en) 1994-04-06 1997-10-03 Defarges Alain Moreau Improvements made to a needleless jet injection device.
GB9408500D0 (en) 1994-04-28 1994-06-22 Pa Consulting Services Improvements in or relating to injection devices
US5411488A (en) 1994-05-06 1995-05-02 Sterling Winthrop Inc. Pre-filled syringe and pre-filled cartridge having an improved plunger and plunger rod for reducing syringing force
AU1994295A (en) 1994-05-16 1995-12-05 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
US5609584A (en) 1994-05-18 1997-03-11 Gettig Technologies, Inc. Adaptor system for use with a syringe
DE29522418U1 (en) 1994-05-30 2003-05-08 B D Medico S.A.R.L., Mies injection device
GB9412301D0 (en) 1994-06-17 1994-08-10 Safe T Ltd Hollow-needle drugs etc applicators
AU2945495A (en) * 1994-06-24 1996-01-19 Icu Medical, Inc. Fluid transfer device and method of use
CA2154853C (en) * 1994-07-27 2007-01-16 John Glyndwr Wilmot Nipple plunger
DE4428467A1 (en) 1994-08-11 1996-02-15 Dietmar Dr Med Enk Syringe, e.g. for spinal anaesthetics
WO1996008208A1 (en) 1994-09-16 1996-03-21 Biopsys Medical, Inc. Methods and devices for defining and marking tissue
AUPM922394A0 (en) 1994-11-03 1994-11-24 Astra Pharmaceuticals Pty Ltd Plastic syringe with overcap
US5637094A (en) 1994-11-04 1997-06-10 Pos-T-Vac, Inc. Multiple dosage syringe
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
US5607395A (en) * 1995-02-02 1997-03-04 Ragsdale; Ronald Device for remote injection of animals
GB9504878D0 (en) 1995-03-10 1995-04-26 Weston Medical Ltd Viscously coupled actuator
GB9506087D0 (en) 1995-03-24 1995-05-10 Owen Mumford Ltd Improvements relating to medical injection devices
US5779668A (en) 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
FR2733155B1 (en) 1995-04-18 1997-09-19 Tebro RECHARGEABLE SELF-INJECTOR
FR2733687B1 (en) * 1995-05-04 1997-10-03 Brunel Marc METHOD FOR MANUFACTURING A PRE-FILLED INJECTION DEVICE CONTAINING A DOSE OF LIQUID TO BE INJECTED, AND INJECTION DEVICE PRODUCED
FR2736553B1 (en) 1995-07-12 1998-01-09 Soc Et Et D Applic Tech Sedat INJECTION SYRINGE, IN PARTICULAR LIQUID MEDICAL PRODUCTS, WITH MOBILE NEEDLE PROTECTOR
DE29513214U1 (en) 1995-08-21 1997-01-02 Adamaszek, Franz-Heinz, 70193 Stuttgart Dosing and automatic injection system
US5520653A (en) 1995-09-01 1996-05-28 Medrad, Inc. Syringe adapter for front-loading medical injector
US5674204A (en) 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
FR2739564B3 (en) 1995-10-06 1998-04-10 Calomili Gerard SINGLE USE SAFETY SYRINGE, WITH WHICH THE NEEDLE CANNULA AUTOMATICALLY AND FULLY RETRACTS AFTER FIRST USE
US5658259A (en) * 1995-10-19 1997-08-19 Meridian Medical Technologies, Inc. Dental cartridge assembly auto-injector with protective needle cover
US5807334A (en) 1995-10-20 1998-09-15 Hodosh; Milton Fluid dispensing apparatus
US6159161A (en) 1995-10-20 2000-12-12 Hodosh; Milton Microprocessor-controlled fluid dispensing apparatus
US5567160A (en) 1995-10-26 1996-10-22 Survival Technology, Inc. Autoinjector training device
US5997513A (en) 1995-11-22 1999-12-07 Smith; Jerry A. Syringe cover cooperating with needle cover
FR2741810B1 (en) 1995-11-30 1998-02-20 Soc Et Et D Applic Tech Sedat SYRINGE FOR THE INJECTION OF AN EXTEMPORANEOUS MIXTURE
US5899879A (en) 1995-12-19 1999-05-04 Genesis Medical Technologies, Inc. Spring-actuated needleless injector
US5609577A (en) 1996-01-29 1997-03-11 Haber; Terry M. Automatically locking hypodermic needle hiding shield for a dose metering syringe
DE19603707A1 (en) 1996-02-02 1997-08-07 Carnaudmetalbox Sa Dosing device for compressible containers
JPH09225029A (en) 1996-02-26 1997-09-02 Material Eng Tech Lab Inc Injector and its manufacture
US5865795A (en) * 1996-02-29 1999-02-02 Medi-Ject Corporation Safety mechanism for injection devices
GB9606829D0 (en) 1996-03-30 1996-06-05 Jeffrey Peter Supplying materials etc
IT1284642B1 (en) 1996-05-02 1998-05-21 Ermanno Greco REFINEMENTS FOR AUTOMATIC SYRINGES FOR INJECTION
GB9612724D0 (en) 1996-06-18 1996-08-21 Owen Mumford Ltd Improvements relating to injection devices
ATE249259T1 (en) 1996-07-05 2003-09-15 Novo Nordisk As DEVICE FOR AUTOMATICALLY INSERTING A NEEDLE
US5709662A (en) 1996-08-23 1998-01-20 Becton Dickinson France, S.A. Cartridge for an injection device
US5843036A (en) 1996-08-23 1998-12-01 Becton Dickinson And Company Non-dosing cartridge for an injection device
US5955177A (en) 1996-09-03 1999-09-21 3M Innovative Properties Company Fire barrier mat
WO1998011927A1 (en) 1996-09-20 1998-03-26 Disetronic Licensing Ag Expulsion member for advancing the stopper of a syringe ampoule and a corresponding stopper
US5697908A (en) 1996-09-26 1997-12-16 Becton Dickinson France, S.A. Lockable safety shield for a prefillable syringe
AU7398096A (en) 1996-10-09 1998-05-05 Equidyne Systems, Incorporated Hypodermic jet injector
US5873861A (en) 1996-11-12 1999-02-23 Medrad, Inc. Plunger systems
US6090897A (en) 1996-12-09 2000-07-18 Nippon Shokubai Co., Ltd. Curable resin composition and its use
US5817058A (en) 1996-12-23 1998-10-06 Shaw; Thomas J. Retractable catheter introducer structure
US6203530B1 (en) 1997-01-28 2001-03-20 Pos-T-Vac, Inc. Auto-injection device
BR9700930A (en) 1997-02-07 1998-12-08 Rhone Poulenc Rorer Gmbh Unit for sale intended for parenteral application a device for the execution of parenteral application as well as a refill unit for the above mentioned unit for sale
CN1190599A (en) 1997-02-12 1998-08-19 约尼-鲍伦斯·劳拉有限公司 Complete set of commodity, equipment and spare parts for external use of intestines and stomach
US6159184A (en) 1997-03-10 2000-12-12 Safety Syringes, Inc. Disposable self-shielding unit dose syringe guard
US6331172B1 (en) 1997-04-14 2001-12-18 Baxter International Inc. Applicator for dispensing measured quantities with use of controlled suction
US6454746B1 (en) 1997-06-04 2002-09-24 Eli Lilly And Company Medication delivery apparatus
GB9714948D0 (en) * 1997-07-16 1997-09-17 Owen Mumford Ltd Improvements relating to injection devices
US5865804A (en) * 1997-07-16 1999-02-02 Bachynsky; Nicholas Rotary cam syringe
US5954738A (en) 1997-07-31 1999-09-21 Bayer Corporation Blood sampling device with lancet damping system
GB9716065D0 (en) 1997-07-31 1997-10-01 Owen Mumford Ltd Improvements relating to injection devices
US6171276B1 (en) 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
ES2210799T3 (en) 1997-08-21 2004-07-01 Ares Trading S.A. INJECTION DEVICE.
US6569115B1 (en) 1997-08-28 2003-05-27 Mdc Investment Holdings, Inc. Pre-filled retractable needle injection device
AU9202398A (en) 1997-09-29 1999-04-23 Becton Dickinson & Company Injection device and drug cartridge for preventing cross-use of the device and drug cartridge
US6004296A (en) 1997-09-30 1999-12-21 Becton Dickinson France, S.A. Lockable safety shield assembly for a prefillable syringe
US6090078A (en) 1997-09-30 2000-07-18 Becton, Dickinson And Company Dampening devices and methods for needle retracting safety vascular access devices
IE970782A1 (en) 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
US6045534A (en) 1997-10-27 2000-04-04 Sarcos, Inc. Disposable fluid injection module
US6086562A (en) 1997-10-27 2000-07-11 Sarcos, Inc. Disposable automatic injection device
JP2001521793A (en) 1997-10-30 2001-11-13 ラボラトアール アゲータン Medical safety syringe
FR2770404B1 (en) 1997-11-05 2000-01-28 Sedat AUTOMATIC INJECTOR WITH NEEDLE RETRACTION AT THE END OF INJECTION
US6015438A (en) 1997-11-14 2000-01-18 Retractable Technologies Inc. Full displacement retractable syringe
US5913843A (en) 1997-11-26 1999-06-22 Jentzen; S. William Dampening device for spring movement
CA2484271C (en) 1997-12-31 2007-04-24 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
IT1304761B1 (en) 1998-01-20 2001-03-29 Nardino Righi DISPOSABLE SAFETY SYRINGE.
DE29801168U1 (en) 1998-01-24 1999-08-12 Medico Dev Investment Co Injection device
FR2774294B1 (en) 1998-02-04 2000-04-14 Marc Brunel DEVICE FOR AUTOMATICALLY INJECTING A DOSE OF MEDICINAL PRODUCT
GB9803084D0 (en) 1998-02-14 1998-04-08 Owen Mumford Ltd Improvements relating to medical injection devices
CA2229522A1 (en) 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
GB9808408D0 (en) 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
US6209738B1 (en) * 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
DE19819409A1 (en) 1998-04-30 1999-11-11 Schering Ag Injection device
JP2002513547A (en) 1998-05-07 2002-05-14 アクゾ・ノベル・エヌ・ベー Use of interleukin-18 as a vaccine adjuvant
DE19821933C1 (en) 1998-05-15 1999-11-11 Disetronic Licensing Ag Device for administering an injectable product
DE19822031C2 (en) 1998-05-15 2000-03-23 Disetronic Licensing Ag Auto injection device
FR2778853B1 (en) 1998-05-19 2000-12-22 Sedat INJECTION SYRINGE WITH SPRING LOADED NEEDLE PROTECTOR
GB2338033A (en) 1998-06-02 1999-12-08 Huntleigh Technology Plc Pressure control system
WO2000006227A1 (en) * 1998-07-27 2000-02-10 Medi-Ject Corporation Loading mechanism for medical injector assembly
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
US6428528B2 (en) 1998-08-11 2002-08-06 Antares Pharma, Inc. Needle assisted jet injector
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
WO2000013723A2 (en) 1998-09-04 2000-03-16 Owen Mumford Limited Improvements relating to fluid tranfer assemblies
FR2784033B1 (en) 1998-10-01 2000-12-22 Marc Brunel SINGLE USE INJECTION DEVICE FOR PRE-FILLED
US6506177B2 (en) 1998-10-14 2003-01-14 Sergio Landau Needle-less injection system
SE9803662D0 (en) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab autoinjector
JP2000126293A (en) 1998-10-28 2000-05-09 Shimadzu Corp Needleless injector
US20020173748A1 (en) 1998-10-29 2002-11-21 Mcconnell Susan Reservoir connector
WO2000029049A1 (en) 1998-11-13 2000-05-25 Elan Pharma International Limited Drug delivery systems and methods
US6783509B1 (en) 1998-11-18 2004-08-31 Bioject Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6689093B2 (en) 1998-11-18 2004-02-10 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6264629B1 (en) 1998-11-18 2001-07-24 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
DE29822494U1 (en) 1998-12-17 2000-05-04 Medico Development Investment Co., Ascona Injection device
US6036675A (en) 1999-02-03 2000-03-14 Specialized Health Products, Inc. Safety sterile cartride unit apparatus and methods
GB9903475D0 (en) 1999-02-17 1999-04-07 Owen Mumford Ltd Improvements relating to injection devices
IL128709A (en) 1999-02-24 2004-09-27 Teva Medical Ltd Fluid sampling apparatus
US6258062B1 (en) 1999-02-25 2001-07-10 Joseph M. Thielen Enclosed container power supply for a needleless injector
FR2790948B1 (en) * 1999-03-18 2001-06-22 Sedat DEVICE FOR BIDIRECTIONAL TRANSFER OF A LIQUID BETWEEN A BOTTLE AND A CAPSULE
WO2000061209A1 (en) 1999-04-14 2000-10-19 Thomas Randall Inkpen Needle injection-facilitating device
NO310224B1 (en) 1999-04-22 2001-06-11 Medical Needle As Disposable syringe with automatically retractable needle
US20040069044A1 (en) 1999-04-29 2004-04-15 Gilad Lavi Device for measuring a volume of drug
SE9901736D0 (en) 1999-05-12 1999-05-12 Pharmacia & Upjohn Ab Injectino device and method for ITS operation
NZ335985A (en) 1999-05-27 2001-04-27 Simcro Tech Ltd Measuring dispenser for a container
US6330960B1 (en) 1999-06-04 2001-12-18 Mcneil-Ppc, Inc. Squeeze dispenser
DE60023511T2 (en) 1999-07-15 2006-04-20 Bracco International B.V. PISTON FOR SYRINGE
CA2379769C (en) 1999-07-27 2009-04-14 Pharma Consult Ges.M.B.H. Device for automatically injecting injection liquids
JP2001046498A (en) 1999-08-06 2001-02-20 Shimadzu Corp Needleless syringe
US6491667B1 (en) * 1999-08-31 2002-12-10 Becton, Dickinson And Company Syringe tip cap
US6162199A (en) * 1999-09-20 2000-12-19 Geringer; Joseph Robert Device for loading a syringe from a vial
FR2799376B1 (en) 1999-10-07 2002-01-18 Marc Brunel SINGLE USE INJECTION DEVICE
FR2799654B1 (en) 1999-10-13 2002-01-11 Sod Conseils Rech Applic DEVICE FOR RECONSTRUCTING A THERAPEUTIC SOLUTION, SUSPENSION OR DISPERSION AND PREPARATION AND PACKAGING METHOD THEREOF
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6391003B1 (en) 1999-10-25 2002-05-21 Antares Pharma, Inc. Locking mechanism for a jet injector
US7029457B2 (en) 1999-11-23 2006-04-18 Felton International, Inc. Jet injector with hand piece
ATE274941T1 (en) 1999-12-08 2004-09-15 Union Medico INFUSION DEVICE
US6425885B1 (en) * 1999-12-20 2002-07-30 Ultradent Products, Inc. Hydraulic syringe
US6926696B2 (en) 1999-12-23 2005-08-09 Owais Mohammed Hypodermic syringe needle assembly and method of making the same
DE60111357T2 (en) 2000-01-07 2006-05-04 Glaxo Group Ltd., Greenford Injection device for administering a particular medical fluid dose
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6190363B1 (en) 2000-01-24 2001-02-20 Bracco Diagnostics, Inc. Self-aligning plunger rod
GB0002095D0 (en) 2000-01-28 2000-03-22 Novartis Ag Device
US6595957B1 (en) 2000-01-31 2003-07-22 Ethicon, Inc. Surgical fluid management system with a dampening chamber
JP2001212237A (en) 2000-01-31 2001-08-07 Shimadzu Corp Neeldeless syringe
DE50007821D1 (en) * 2000-02-16 2004-10-21 Haselmeier S A R L METHOD FOR THE RECONSTITUTION OF AN INJECTION LIQUID, AND INJECTION DEVICE FOR IMPLEMENTING SUCH A METHOD
GB0003790D0 (en) 2000-02-18 2000-04-05 Astrazeneca Uk Ltd Medical device
FR2805868A1 (en) 2000-03-02 2001-09-07 Peugeot Citroen Automobiles Sa Elastic component such as compression spring used in vehicle manufacture is made from cylinder of flexible material with series of transverse slots
JP4675537B2 (en) 2000-03-02 2011-04-27 株式会社大協精工 Prefilled syringe assembly
AU2001243420A1 (en) 2000-03-06 2001-09-17 Mdc Investment Holdings, Inc. Hypodermic syringe with retractable needle
US6832992B2 (en) 2000-03-07 2004-12-21 Becton, Dickinson And Company Passive safety device for needle of blood collection set
US6855130B2 (en) 2000-03-07 2005-02-15 Becton, Dickinson And Company Passive safety device for needle of IV infusion or blood collection set
GB0007071D0 (en) 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
US6371959B1 (en) * 2000-04-05 2002-04-16 Michael E. Trice Radiolucent position locating device and drill guide
US6471677B2 (en) 2000-04-06 2002-10-29 Gem Plastics, Inc. Fluid collection device with protective shield
US6558348B2 (en) 2000-04-07 2003-05-06 Equidyne Systems, Inc. Low cost disposable needleless injector system for variable and fixed dose applications
AU2001250572A1 (en) 2000-04-07 2001-10-23 Epigenomics Ag Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations
GB0008955D0 (en) 2000-04-12 2000-05-31 Owen Mumford Ltd An injector pack
US6607508B2 (en) 2000-04-27 2003-08-19 Invivotech, Inc. Vial injector device
US6183134B1 (en) 2000-05-04 2001-02-06 Illinois Tool Works, Inc. High internal force resistant peel sealable zipper
US6613022B1 (en) 2000-05-05 2003-09-02 Safety Syringes, Inc. Passive needle guard for syringes
EA003971B1 (en) 2000-05-15 2003-12-25 Арес Трейдинг С.А. Storage container for at least one hypodermic needle
US6716198B2 (en) 2000-05-18 2004-04-06 Novo Nordisk A/S Injection device
US6740062B2 (en) 2000-05-22 2004-05-25 Pharmacia Ab Medical device
US6517517B1 (en) 2000-06-08 2003-02-11 Mayo Foundation For Medical Education And Research Automated injection device for administration of liquid medicament
US6585690B1 (en) 2000-06-29 2003-07-01 Becton Dickinson And Company Hypodermic syringe with selectivity retractable needle
AUPQ867900A0 (en) * 2000-07-10 2000-08-03 Medrad, Inc. Medical injector system
US6986760B2 (en) 2000-08-02 2006-01-17 Becton, Dickinson And Company Pen needle and safety shield system
FR2812817B1 (en) 2000-08-09 2002-10-31 Sanofi Synthelabo PROTECTION DEVICE FOR A SYRINGE NEEDLE
US20020032412A1 (en) * 2000-08-24 2002-03-14 John Riemelmoser Syringe with retractable needle and a single use syringe
WO2002017996A1 (en) 2000-08-29 2002-03-07 Novo Nordisk A/S Automatic injection device with torsion function for retraction of needle
CA2422692A1 (en) * 2000-09-21 2002-03-28 Elan Pharma International Limited Reconstitution and injection system
JP3941366B2 (en) 2000-09-22 2007-07-04 フジノン株式会社 Syringe device stopper
FR2815543B1 (en) 2000-10-19 2003-10-24 Sedat SELF-INJECTION SYRINGE OF AN EXTEMPORANEOUS MIXTURE
WO2002040854A1 (en) 2000-11-17 2002-05-23 Isuzu Motors Limited Needle lift damper device of injector for fuel injection and needle lift damping method
IT1320104B1 (en) 2000-11-27 2003-11-18 Paolo Versini INJECTOR DEVICE FOR MEDICAL AND COSMETIC TREATMENTS.
US6569085B2 (en) 2001-08-16 2003-05-27 Syntheon, Llc Methods and apparatus for delivering a medical instrument over an endoscope while the endoscope is in a body lumen
SE518981C2 (en) 2000-12-14 2002-12-17 Shl Medical Ab autoinjector
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
US6485460B2 (en) 2001-01-12 2002-11-26 Bracco Diagnostics, Inc. Tamper evident syringe barrel
EP1351730B1 (en) 2001-01-18 2006-06-28 Medrad, Inc. Syringe interfaces and adapters for use with medical injectors
US6811545B2 (en) 2001-01-31 2004-11-02 Vincent L. Vaillancourt Safety needle
US6673049B2 (en) 2001-02-15 2004-01-06 Disetronic Licensing Ag Injection device for injecting fluid
US6645170B2 (en) 2001-03-05 2003-11-11 Bioject Medical Technologies, Inc. Simplified disposable needle-free injection apparatus and method
US6471669B2 (en) 2001-03-05 2002-10-29 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
CN1509192A (en) 2001-03-13 2004-06-30 MDCͶ�ʿعɹ�˾ Pre-filled safety vial injector
EP1383555A2 (en) 2001-03-15 2004-01-28 Mdc Investment Holdings, Inc. Retractable needle medical device for injecting fluid from a pre-filled cartridge
DK3210637T3 (en) * 2001-04-06 2021-04-06 Hoffmann La Roche Infusion set
GB0109001D0 (en) 2001-04-10 2001-05-30 Glaxo Group Ltd Dispenser
GB0109002D0 (en) 2001-04-10 2001-05-30 Glaxo Group Ltd Dispenser
US6755220B2 (en) 2001-04-27 2004-06-29 Penjet Corporation Method and apparatus for filling or refilling a needle-less injector
US6648850B2 (en) 2001-06-08 2003-11-18 Bioject, Inc. Durable needle-less jet injector apparatus and method
JP4377222B2 (en) 2001-07-09 2009-12-02 ベクトン・ディキンソン・アンド・カンパニー Needle shield assembly with hinged needle shield and flexible cannula lock
DE10137962A1 (en) 2001-08-07 2003-02-20 Roesch Ag Medizintechnik Ampule for injection device for injecting medium into human or animal tissues without needle, comprising plug which closes chamber with injection medium, and is penetrated by hollow needle
WO2003015855A1 (en) 2001-08-09 2003-02-27 Becton, Dickinson And Company Retracting needle safety device
GB0119520D0 (en) 2001-08-10 2001-10-03 Owen Mumford Ltd Improvements relating to injection devices
DE10140704A1 (en) 2001-08-18 2003-03-06 Vetter & Co Apotheker Process for mixing a poorly soluble pharmaceutical substance with a solvent and syringe to apply the process
US7235063B2 (en) 2001-08-21 2007-06-26 D'antonio Consultants International, Inc. Hypodermic injection system
US7488306B2 (en) 2001-09-26 2009-02-10 Smiths Medical Asd, Inc. Needle protection device with dampener
WO2003028785A2 (en) * 2001-10-03 2003-04-10 Medical Instill Technologies, Inc. Syringe and reconstitution syringe
FR2830765B1 (en) 2001-10-15 2004-07-23 Plastic Omnium Cie SAFETY DEVICE FOR A SYRINGE
US6796967B2 (en) 2001-10-22 2004-09-28 Nps Pharmaceuticals, Inc. Injection needle assembly
US7569035B1 (en) 2001-11-02 2009-08-04 Meridian Medical Technologies, Inc. Automatic injector with anti-coring needle
US6607510B2 (en) 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
HU227056B1 (en) 2001-11-09 2010-06-28 Alza Corp Collapsible syringe cartridge related cases
DE60236949D1 (en) 2001-11-09 2010-08-19 Alza Corp PNEUMATICALLY DRIVEN AUTO INJECTOR
EP1448255A1 (en) 2001-11-14 2004-08-25 Riemser Arzneimittel AG Injection device and ampoule, particularly for an injection device
US20030105430A1 (en) * 2001-11-30 2003-06-05 Elan Pharma International Limited Wil House Automatic injector
US6863659B2 (en) 2001-12-10 2005-03-08 Bruce George Sharpe Sharp safe hydraulic retractable syringe
WO2003051423A2 (en) 2001-12-13 2003-06-26 Becton Dickinson And Company Needle closure system removal device
JP4046998B2 (en) 2001-12-14 2008-02-13 ロレアル Applicator
EP1455869A2 (en) 2001-12-19 2004-09-15 Disetronic Licensing AG Administration device comprising an expulsion member and a stopper covering
US20040143224A1 (en) 2002-01-07 2004-07-22 Jeffrey Field Method and apparatus for inhibiting fluid loss from a syringe
GB0200444D0 (en) 2002-01-10 2002-02-27 Owen Mumford Ltd Improvements relating to medical injection devices
US6875205B2 (en) * 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
WO2003068290A2 (en) 2002-02-11 2003-08-21 Antares Pharma, Inc. Intradermal injector
DE10207276A1 (en) 2002-02-21 2003-09-11 Disetronic Licensing Ag Needle insertion device with a transversely movable holding element
GB0204673D0 (en) 2002-02-28 2002-04-10 Dca Design Int Ltd Improvements in and relating to a medicament delivery device
GB0206560D0 (en) 2002-03-20 2002-05-01 Glaxo Group Ltd Novel device
AU2003201335B2 (en) 2002-03-20 2009-07-23 Becton, Dickinson And Company Shieldable needle assembly with biased safety shield
JP2003298253A (en) 2002-03-29 2003-10-17 Denso Corp Housing structure and mounting structure of electronic control apparatus
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US20030196928A1 (en) 2002-04-19 2003-10-23 Parsons J. Stuart Multi-component ampule
US20030199814A1 (en) 2002-04-19 2003-10-23 Parsons J. Stuart Multi-component ampule
ES2333710T3 (en) * 2002-04-24 2010-02-26 Ares Trading S.A. DEVICE FOR PREPARING A MEDICINAL LIQUID.
KR101009270B1 (en) 2002-05-02 2011-01-18 칠락 게엠베하 인테르나티오날 Injection device
GB2388033A (en) 2002-05-02 2003-11-05 Pa Consulting Services Automatic injection device
GB2396298A (en) 2002-12-17 2004-06-23 Pa Consulting Services Injection device and drive coupling
US7207973B2 (en) 2002-05-10 2007-04-24 Becton, Dickinson And Company Passive safety shield system for injection devices
US6808507B2 (en) 2002-05-10 2004-10-26 Cambridge Biostability Ltd. Safety injectors
US6776777B2 (en) 2002-05-10 2004-08-17 Becton, Dickinson And Company Passive safety shield system for injection devices
GB0211294D0 (en) 2002-05-17 2002-06-26 Owen Mumford Ltd Improvements relating to injection devices
US6979316B1 (en) 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
US7156823B2 (en) 2002-06-04 2007-01-02 Bioject Inc. High workload needle-free injection system
US6676630B2 (en) 2002-06-04 2004-01-13 Bioject Medical Technologies, Inc. Needle-free injection system
WO2003103750A1 (en) 2002-06-05 2003-12-18 Elan Pharma International Limited Injector adapter and combination thereof
US6764465B2 (en) 2002-06-24 2004-07-20 Long Hsiung Chen Syringe with retractable needle and safety lock
MY139059A (en) * 2002-06-24 2009-08-28 Alza Corp Reusable, spring driven autoinjector
DE60335108D1 (en) 2002-07-02 2011-01-05 Panasonic Corp
WO2004007554A1 (en) 2002-07-16 2004-01-22 Eyegene Inc. Protein for diagnosing diabetic retinopathy
TW572761B (en) 2002-07-17 2004-01-21 Ming-Jeng Shiu Syringe with retraction force
US7097634B2 (en) * 2002-07-31 2006-08-29 Alza Corporation Injection device providing automatic needle retraction
US20040087897A1 (en) 2002-07-31 2004-05-06 Birger Hjertman Device and method for liquid jet generation
GB2421689B (en) 2002-08-05 2007-03-07 Caretek Medical Ltd Drug delivery system
FR2845052B1 (en) * 2002-08-06 2005-06-24 Fico Mirrors ASSEMBLY FOR THE ARTICULATED CONNECTION OF A RETROVISOR MIRROR
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
CA2494825C (en) 2002-08-21 2009-02-17 Pharmacia Corporation Injectable pharmaceutical suspension in a two-chamber vial
US9486581B2 (en) 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
US7160913B2 (en) * 2002-09-13 2007-01-09 Thomas Jefferson University Methods and kit for treating Parkinson's disease
EP1401089A1 (en) 2002-09-18 2004-03-24 Continental ISAD Electronic Systems GmbH & Co. KG Electrical machine, formed as starter, generator or starter-generator for a vehicle
WO2004028598A1 (en) 2002-09-24 2004-04-08 Shl Medical Ab Injecting device
GB0222731D0 (en) 2002-10-01 2002-11-06 Parker David W Improvements in or relating to hypodermic syringes
DE10248061A1 (en) 2002-10-15 2004-05-06 Disetronic Licensing Ag Injection device with idle stroke
GB0224505D0 (en) 2002-10-22 2002-11-27 Medical House The Plc Needles injection device
WO2004101025A2 (en) 2003-05-09 2004-11-25 Intravacc, Inc. Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection
US6939319B1 (en) 2002-11-20 2005-09-06 Conrad Anstead Process and device for single use, needle-free intradermal, subcutaneous, or intramuscular injections
KR20040043896A (en) 2002-11-20 2004-05-27 삼성전자주식회사 Push button
WO2004047890A1 (en) 2002-11-25 2004-06-10 Tecpharma Licensing Ag Device for automatically injecting an active agent
CH695926A5 (en) 2002-11-25 2006-10-31 Tecpharma Licensing Ag Device for automatically injecting an active ingredient.
AU2003280270B2 (en) 2002-11-25 2008-01-24 Tecpharma Licensing Ag Injection apparatus comprising a needle-protecting device
JP2006507061A (en) 2002-11-25 2006-03-02 テクファーマ・ライセンシング・アクチェンゲゼルシャフト Automatic injection device with resettable release safety device
CH696186A5 (en) 2002-11-25 2007-02-15 Tecpharma Licensing Ag Device for securing hypodermic needles.
GB0228483D0 (en) * 2002-12-06 2003-01-08 Boots Healthcare Int Ltd Bottle
US6939330B1 (en) 2002-12-12 2005-09-06 Medsolve Llc Syringe insertion system
GB2396816A (en) 2002-12-17 2004-07-07 Pa Consulting Services Injection device
GB0229345D0 (en) 2002-12-17 2003-01-22 Safe T Ltd Hollow needle applicators
US7252651B2 (en) 2003-01-07 2007-08-07 Becton, Dickinson And Company Disposable injection device
US6767336B1 (en) 2003-01-09 2004-07-27 Sheldon Kaplan Automatic injector
JP4599345B2 (en) * 2003-01-22 2010-12-15 デュオジェクト・メディカル・システムズ・インコーポレイテッド Drug delivery system and method using the same
CA2514673A1 (en) * 2005-08-05 2007-02-05 Duoject Medical Systems Inc. Fluid transfer assembly for pharmaceutical delivery system and method for using same
FR2852851B1 (en) 2003-03-25 2006-01-06 Sedat NEEDLE PROTECTION DEVICE FOR SYRINGE, AND INJECTION DEVICE COMPRISING SYRINGE AND PROTECTIVE DEVICE
US7115114B2 (en) 2003-05-02 2006-10-03 Becton, Dickinson And Company Medical device having releasable retainer
US6805686B1 (en) 2003-05-06 2004-10-19 Abbott Laboratories Autoinjector with extendable needle protector shroud
GB0312852D0 (en) 2003-06-05 2003-07-09 Owen Mumford Ltd Improvements relating to syringe firing mechanisms
JP2007511252A (en) * 2003-06-09 2007-05-10 ニプロ ダイアビティーズ システムズ，インコーポレイテッド Coupling system in infusion pump
DE10327254B4 (en) * 2003-06-17 2010-01-28 Disetronic Licensing Ag Modular infusion pump
EP1491478B1 (en) 2003-06-25 2007-05-09 Müller Martini Holding AG Diverting device
US20060069198A1 (en) * 2003-06-30 2006-03-30 Nissin Chemical Industry Co., Ltd. Building exterior wall-coating emulsion compositions and building exterior walls
GB2403711A (en) 2003-07-07 2005-01-12 Gw Pharma Ltd Drug dispenser with controlled access
JP3883527B2 (en) 2003-07-17 2007-02-21 ニプロ株式会社 Transfer needle
US7500963B2 (en) 2003-07-22 2009-03-10 Safety Syringes, Inc. Systems and methods for automatic medical injection with safeguard
GB2404338B (en) 2003-07-30 2007-01-24 Safe T Ltd Actuator and containment device for a syringe
US20050027255A1 (en) 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
DE20311996U1 (en) 2003-08-01 2003-10-16 Hoelzle Dieter Tech Projekte injection device
US8932264B2 (en) 2003-08-11 2015-01-13 Becton, Dickinson And Company Medication delivery pen assembly with needle locking safety shield
DE10339794A1 (en) 2003-08-28 2005-04-07 Tecpharma Licensing Ag Administering device with a protective cap removal device and a needle protection sleeve blocking device
DE10340586A1 (en) 2003-09-03 2005-04-07 Tecpharma Licensing Ag Mixing device for multi-chamber ampoule
DE10342058B4 (en) 2003-09-11 2007-10-25 Tecpharma Licensing Ag Administration device for an injectable product with a trigger safety device
US7097071B2 (en) * 2003-09-16 2006-08-29 Mark L Anderson Dispenser container technology
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto-injector
FR2860162B1 (en) 2003-09-26 2006-06-02 Becton Dickinson France DEVICE FOR PROTECTING AN INJECTION APPARATUS
US20050085776A1 (en) 2003-10-16 2005-04-21 Edgar Hommann Injection device for administering a fluid product
DE10348185A1 (en) 2003-10-16 2005-05-19 Tecpharma Licensing Ag Injection device for administering fluid product e.g. insulin, comprising injection needle and needle cover arranged on holder or on casing so that it can shift and generally surrounds injection needle in advanced position
AU2004279651B2 (en) 2003-10-16 2010-07-08 Tecpharma Licensing Ag Injection device for administering a fluid product
JP2005141729A (en) 2003-10-17 2005-06-02 Fuji Xerox Co Ltd Method, device, and program for peripheral apparatus and control and method, device, and program for display control
FR2861310B1 (en) 2003-10-22 2006-09-22 Plastef Investissements SECURE INJECTION SYRINGE DEVICE
DE10351599A1 (en) 2003-11-05 2005-06-16 Tecpharma Licensing Ag Auto-injection device
DE10351598A1 (en) 2003-11-05 2005-06-16 Tecpharma Licensing Ag Auto-injection device
US20050101919A1 (en) 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
US20050125019A1 (en) 2003-12-05 2005-06-09 Paul Kudrna Lancet device and method
DK1703929T3 (en) 2003-12-18 2010-09-20 Tecpharma Licensing Ag Detachable injection device
CH696421A5 (en) 2003-12-18 2007-06-15 Tecpharma Licensing Ag Autoinjector with arresting the drug container.
JP2007514489A (en) 2003-12-18 2007-06-07 ノボ・ノルデイスク・エー／エス Nozzle device having skin stretching means
US20050137523A1 (en) 2003-12-22 2005-06-23 Wyatt Philip W. Medicament administration apparatus
AU2005205966B2 (en) 2004-01-23 2010-08-05 Shl Medical Ag Injection device
GB2410188B (en) 2004-01-23 2006-01-25 Medical House Plc Injection device
FR2865407B1 (en) 2004-01-27 2006-04-28 Crossject NEEDLELESS SYRINGE WITH INJECTOR RECEPTACLE AMORTISSANT
US7717879B2 (en) * 2004-02-03 2010-05-18 Smjm Inject Gmbh Anesthetic syringe
US20050209554A1 (en) * 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
US20090209554A1 (en) * 2004-03-24 2009-08-20 Array Biopharma Inc. Thiazoliums as transketolase inhibitors
US20050222539A1 (en) 2004-03-30 2005-10-06 Pediamed Pharmaceuticals, Inc. Automatic injection device
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
NL1026187C2 (en) * 2004-05-13 2005-11-15 Univ Eindhoven Tech Device for generating corona discharges.
US20050261633A1 (en) 2004-05-19 2005-11-24 Khalaj Ben M Rechargeable handheld injection device with reversible drive having adjustable syringe cradle
GB2414401B (en) 2004-05-28 2009-06-17 Cilag Ag Int Injection device
DE102004026745B4 (en) * 2004-05-28 2013-06-20 Justus-Liebig-Universität Giessen Method and device for applying nanoscale polymer fibers as a carrier for agricultural active ingredients
US7717874B2 (en) 2004-05-28 2010-05-18 Bioject, Inc. Needle-free injection system
GB2414409B (en) 2004-05-28 2009-11-18 Cilag Ag Int Injection device
GB2414406B (en) 2004-05-28 2009-03-18 Cilag Ag Int Injection device
CA2568683C (en) 2004-05-28 2013-07-23 Cilag Gmbh International Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414404B (en) 2004-05-28 2009-06-03 Cilag Ag Int Injection device
GB2414403B (en) 2004-05-28 2009-01-07 Cilag Ag Int Injection device
GB2414398B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414399B (en) 2004-05-28 2008-12-31 Cilag Ag Int Injection device
US20050273054A1 (en) 2004-06-03 2005-12-08 Florida Atlantic University Epinephrine auto-injector
ITMI20041471A1 (en) 2004-07-21 2004-10-21 Sergio Restelli STANDARD SYRINGE SAFETY KIT FOR SINGLE USE SAFETY SYRINGE
US20060100588A1 (en) * 2004-07-23 2006-05-11 Lennart Brunnberg Needle handling device
US7449012B2 (en) * 2004-08-06 2008-11-11 Meridian Medical Technologies, Inc. Automatic injector
US20060069350A1 (en) 2004-09-30 2006-03-30 Buenger David R Medical syringe injector pen
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20060089594A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device
US20060089593A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device for individual users
US7255689B2 (en) 2004-10-29 2007-08-14 Safety Syringes, Inc. Syringe with anti-rotation for luer lock
US7412273B2 (en) 2004-11-15 2008-08-12 Biosense Webster, Inc. Soft linear mapping catheter with stabilizing tip
US7905352B2 (en) 2004-12-06 2011-03-15 Washington Biotech Corporation Kits containing medicine injection devices and containers
US7297136B2 (en) 2004-12-06 2007-11-20 Wyrick Ronald E Medicine injection devices and methods
BRPI0518961A2 (en) 2004-12-09 2008-12-16 West Pharm Serv Inc coupling for automatic injection device
US7407494B2 (en) 2005-01-31 2008-08-05 Bostroem Anders Device for delivering medicament
US20060258986A1 (en) 2005-02-11 2006-11-16 Hunter Ian W Controlled needle-free transport
US20060184103A1 (en) * 2005-02-17 2006-08-17 West Pharmaceutical Services, Inc. Syringe safety device
DE102005007614A1 (en) * 2005-02-18 2006-08-24 Tecpharma Licensing Ag Auto-injector with a release lock
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
GB2424838B (en) 2005-04-06 2011-02-23 Cilag Ag Int Injection device (adaptable drive)
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2424835B (en) 2005-04-06 2010-06-09 Cilag Ag Int Injection device (modified trigger)
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2424837B (en) 2005-04-06 2010-10-06 Cilag Ag Int Injection device
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
FR2884721A1 (en) 2005-04-20 2006-10-27 Becton Dickinson France Soc Pa Assistance device for device of injection of a product, comprises hollow body for receiving the product, hollow injection needle for penetrating into injection site, piston placed in the body, hollow sleeve with bearing surface
US7618393B2 (en) 2005-05-03 2009-11-17 Pharmajet, Inc. Needle-less injector and method of fluid delivery
US7699802B2 (en) 2005-05-03 2010-04-20 Pharmajet, Inc. Needle-less injector
WO2007035666A2 (en) * 2005-09-19 2007-03-29 Lifescan, Inc. Electrokinetic infusion pump system
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
JP2009511177A (en) 2005-10-11 2009-03-19 イーライ リリー アンド カンパニー Medicine injection device
DE102005052502A1 (en) 2005-11-03 2007-05-16 Tecpharma Licensing Ag Auto-injector activation trigger element
GB2433032A (en) 2005-12-08 2007-06-13 Owen Mumford Ltd Syringe with dose adjustment means
US7981101B2 (en) * 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
US8926562B2 (en) * 2005-12-30 2015-01-06 Hospira, Inc. Syringe holding system
JP4741952B2 (en) 2006-02-02 2011-08-10 Ｉｄｅｃ株式会社 Operation switch
FR2899482A1 (en) 2006-04-11 2007-10-12 Becton Dickinson France Soc Pa Automatic medicament/product injection device for patient, has safety shield coupled to housing, and provided in active state at end of needle insertion step before which product/medicament injection step is not started
US7547300B2 (en) * 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
US20090105685A1 (en) 2006-04-21 2009-04-23 Novo Nordisk A/S Two Stage Jet Injection Device
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
WO2007129324A2 (en) 2006-05-09 2007-11-15 Gil Yigal A disposable injecting device with auto-retraction mechanism
GB2437922B (en) 2006-05-10 2010-12-08 Owen Mumford Ltd Injection device comprising a window and a shutter element
GB2438629B (en) 2006-06-01 2011-02-23 Cilag Gmbh Int Injection device
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
US7618396B2 (en) 2006-08-09 2009-11-17 Avant Medical Corp. Injection system with hidden needles
US7794434B2 (en) 2006-08-23 2010-09-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7828764B2 (en) 2006-08-23 2010-11-09 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7811262B2 (en) 2006-08-23 2010-10-12 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US8167863B2 (en) * 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
CA2564061A1 (en) * 2006-10-16 2008-04-16 Duoject Medical Systems Inc. Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge
WO2008047372A2 (en) 2006-10-19 2008-04-24 Elcam Medical Agricultural Cooperative Association Ltd. Automatic injection device
GB2443606B (en) 2006-11-13 2011-07-20 Cilag Gmbh Int Injection device
ATE514443T1 (en) 2006-12-13 2011-07-15 Shl Group Ab AUTOINJECTOR
GB0625169D0 (en) 2006-12-18 2007-01-24 Medical House Plc The Improved autoinjector
US7871397B2 (en) * 2006-12-26 2011-01-18 Stat Medical Devices, Inc. Pen needle tip
GB2446778A (en) * 2007-02-01 2008-08-27 Pa Knowledge Ltd Syringe adaptor
JP2010527248A (en) * 2007-02-01 2010-08-12 ピーエー ノウレッジ リミテッド Auto-injector and adapter that covers auto-injector needle
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
CN101641125B (en) * 2007-03-09 2013-06-19 伊莱利利公司 Delay mechanism for automatic injection device
WO2008113864A1 (en) 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injection device having trigger safety devices
EP2131898B1 (en) 2007-03-23 2017-08-30 SHL Group AB Auto injector
US7959715B2 (en) * 2007-04-30 2011-06-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir air bubble management
US8434528B2 (en) 2007-04-30 2013-05-07 Medtronic Minimed, Inc. Systems and methods for reservoir filling
WO2008144575A2 (en) * 2007-05-18 2008-11-27 Optiscan Biomedical Corporation Fluid injection and safety system
JP4780034B2 (en) 2007-05-18 2011-09-28 株式会社島津製作所 Needleless syringe
US20080306443A1 (en) 2007-06-06 2008-12-11 Mallinckrodt Inc. Medical Fluid Injector Having Wireless Pressure Monitoring Feature
GB2451665B (en) 2007-08-08 2012-09-26 Cilag Gmbh Int Injection device
GB2451663B (en) 2007-08-08 2012-09-26 Cilag Gmbh Int Injection device
GB2452286B (en) 2007-08-29 2012-09-26 Cilag Gmbh Int Injection system
EP2211946B1 (en) * 2007-09-25 2017-08-09 Becton Dickinson France Autoinjector with trigger positionable in active position by movement of a safety shield and indication of the active position
US8876779B2 (en) 2007-11-12 2014-11-04 Bang & Olufsen Medicom A/S Auto injector with changing anchor locations for a mechanical driver
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461088B (en) * 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461089B (en) * 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
GB2461087B (en) * 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
BRPI0918845A2 (en) 2008-08-29 2015-12-08 Novo Nordisk As medical injection device with time delay indicator
CN102209566B (en) 2008-09-29 2014-03-26 贝克顿迪金森法国公司 Automatic injection device
EP2355872B1 (en) 2008-12-12 2016-01-27 SHL Group AB Medicament delivery device
WO2010112557A1 (en) 2009-03-31 2010-10-07 Sanofi-Aventis Deutschland Gmbh Drug delivery device
GB2472578A (en) 2009-08-10 2011-02-16 Owen Mumford Ltd Sheath removal device and needle protector
DK2470241T4 (en) 2009-08-27 2023-11-20 Sanofi Aventis Deutschland HOUSING COMPONENT FOR A DRUG DELIVERY DEVICE
CN102711875B (en) 2009-10-30 2014-07-16 赛诺菲-安万特德国有限公司 Drug delivery devices and method of assembly
ES2484266T3 (en) 2010-03-01 2014-08-11 Eli Lilly And Company Automatic injection device with delay mechanism including a double function thrust element
EP2399635A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
CA2803154A1 (en) 2010-06-28 2012-01-05 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2399629A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
MY158255A (en) 2010-07-02 2016-09-30 Sanofi Aventis Deutschland Safety device for a pre-filled syringe and injection device
DK2588165T3 (en) 2010-07-02 2020-09-14 Sanofi Aventis Deutschland SAFETY DEVICE FOR A FILLED SYRINGE Syringe, INJECTION DEVICE AND INJECTION KIT
MX2013000061A (en) 2010-07-02 2013-02-15 Sanofi Aventis Deutschland Safety device for a pre-filled syringe and injection device.
EP2468332A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468330A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489380A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Injection device
GB2488579A (en) 2011-03-02 2012-09-05 Owen Mumford Ltd Autoinjector with "injection complete" indicator
AR086930A1 (en) 2011-06-17 2014-01-29 Sanofi Aventis Deutschland CARTRIDGE SUPPORT ASSEMBLY FOR DRUG ADMINISTRATION DEVICES
US9656025B2 (en) 2011-08-31 2017-05-23 Shl Group Ab Injection device
JP6251172B2 (en) 2011-09-29 2017-12-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Drug delivery device and method for drug delivery device
EP2583706A1 (en) 2011-10-21 2013-04-24 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2705862B1 (en) 2012-09-05 2015-07-08 Becton Dickinson France Automatic injection device
EP2705861B1 (en) 2012-09-05 2015-04-22 Becton Dickinson France Automatic injection device
GB2516784B (en) 2013-06-11 2015-10-21 Cilag Gmbh Int Injection device

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