AU2008360625C1 - Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography - Google Patents

Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography Download PDF

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Publication number
AU2008360625C1
AU2008360625C1 AU2008360625A AU2008360625A AU2008360625C1 AU 2008360625 C1 AU2008360625 C1 AU 2008360625C1 AU 2008360625 A AU2008360625 A AU 2008360625A AU 2008360625 A AU2008360625 A AU 2008360625A AU 2008360625 C1 AU2008360625 C1 AU 2008360625C1
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Prior art keywords
antibody
monoclonal antibody
membrane
antibodies
protein
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AU2008360625B2 (en
AU2008360625A1 (en
Inventor
Jerome Bill Jr.
Arick Brown
Christopher Dowd
Timothy Tully
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Genentech Inc
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Genentech Inc
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Publication of AU2008360625B2 publication Critical patent/AU2008360625B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2008360625A 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography Active AU2008360625C1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/073179 WO2010019148A1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography

Publications (3)

Publication Number Publication Date
AU2008360625A1 AU2008360625A1 (en) 2010-02-18
AU2008360625B2 AU2008360625B2 (en) 2016-05-19
AU2008360625C1 true AU2008360625C1 (en) 2017-01-19

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AU2008360625A Active AU2008360625C1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography

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US (2) US10927144B2 (enExample)
EP (3) EP2848625B1 (enExample)
JP (1) JP5666447B2 (enExample)
KR (3) KR101843915B1 (enExample)
CN (1) CN102149724B (enExample)
AU (1) AU2008360625C1 (enExample)
BR (1) BRPI0823046B1 (enExample)
CA (1) CA2731943C (enExample)
CY (1) CY1122221T1 (enExample)
DK (2) DK2848625T3 (enExample)
ES (3) ES2527943T5 (enExample)
FI (1) FI3604324T3 (enExample)
HR (2) HRP20240472T1 (enExample)
HU (2) HUE066562T2 (enExample)
IL (2) IL210912B (enExample)
LT (2) LT3604324T (enExample)
MX (1) MX2011001506A (enExample)
PL (2) PL2848625T3 (enExample)
PT (2) PT3604324T (enExample)
RS (1) RS59232B1 (enExample)
SI (2) SI3604324T1 (enExample)
WO (1) WO2010019148A1 (enExample)

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HUE066562T2 (hu) 2024-08-28
DK2848625T3 (da) 2019-10-07
KR102196883B1 (ko) 2020-12-30
HK1210181A1 (en) 2016-04-15
CN102149724A (zh) 2011-08-10
CA2731943A1 (en) 2010-02-18
EP3604324B1 (en) 2024-02-28
CN102149724B (zh) 2014-04-09
SI3604324T1 (sl) 2024-06-28
ES2749190T3 (es) 2020-03-19
US20120122759A1 (en) 2012-05-17
IL262657B (en) 2021-03-25
EP2321337B1 (en) 2014-10-22
ES2527943T5 (es) 2019-03-07
KR20180137591A (ko) 2018-12-27
EP2321337A1 (en) 2011-05-18
EP2321337B2 (en) 2018-10-10
FI3604324T3 (fi) 2024-05-16
CA2731943C (en) 2016-11-29
EP3604324A1 (en) 2020-02-05
CY1122221T1 (el) 2020-11-25
IL262657A (en) 2018-12-31
LT2848625T (lt) 2019-10-10
JP2011530592A (ja) 2011-12-22
JP5666447B2 (ja) 2015-02-12
PT3604324T (pt) 2024-05-10
IL210912A0 (en) 2011-04-28
AU2008360625B2 (en) 2016-05-19
HUE047316T2 (hu) 2020-04-28
KR20110067099A (ko) 2011-06-21
MX2011001506A (es) 2011-03-15
PL2848625T3 (pl) 2020-01-31
US20210284685A1 (en) 2021-09-16
ES2978373T3 (es) 2024-09-11
EP2321337B9 (en) 2016-11-30
BRPI0823046A2 (pt) 2015-07-28
RS59232B1 (sr) 2019-10-31
ES2527943T3 (es) 2015-02-02
AU2008360625A1 (en) 2010-02-18
HRP20191848T1 (hr) 2019-12-27
LT3604324T (lt) 2024-05-10
KR20180033311A (ko) 2018-04-02
BRPI0823046B1 (pt) 2021-12-14
US10927144B2 (en) 2021-02-23
HRP20240472T1 (hr) 2024-06-21
PL3604324T3 (pl) 2024-07-01
EP2848625A1 (en) 2015-03-18
IL210912B (en) 2019-03-31
EP2848625B1 (en) 2019-07-31
SI2848625T1 (sl) 2019-11-29
KR101843915B1 (ko) 2018-04-02
PT2848625T (pt) 2019-10-25
DK3604324T3 (da) 2024-04-08
WO2010019148A1 (en) 2010-02-18

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Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 05 SEP 2016 .

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 05 SEP 2016