AU2008323848B2 - Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) - Google Patents

Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) Download PDF

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Publication number
AU2008323848B2
AU2008323848B2 AU2008323848A AU2008323848A AU2008323848B2 AU 2008323848 B2 AU2008323848 B2 AU 2008323848B2 AU 2008323848 A AU2008323848 A AU 2008323848A AU 2008323848 A AU2008323848 A AU 2008323848A AU 2008323848 B2 AU2008323848 B2 AU 2008323848B2
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Australia
Prior art keywords
seq
chain variable
variable region
antibody
antigen
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Ceased
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AU2008323848A
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AU2008323848A1 (en
Inventor
Lizhen He
Tibor Keler
Venky Ramakrishna
Laura A. Vitale
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Celldex Therapeutics Inc
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Celldex Therapeutics Inc
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Application filed by Celldex Therapeutics Inc filed Critical Celldex Therapeutics Inc
Publication of AU2008323848A1 publication Critical patent/AU2008323848A1/en
Priority to AU2013201417A priority Critical patent/AU2013201417B2/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
AU2008323848A 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) Ceased AU2008323848B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013201417A AU2013201417B2 (en) 2007-11-07 2013-03-12 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US225307P 2007-11-07 2007-11-07
US61/002,253 2007-11-07
US19155108P 2008-09-10 2008-09-10
US61/191,551 2008-09-10
PCT/US2008/082745 WO2009061996A2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (dec-205)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013201417A Division AU2013201417B2 (en) 2007-11-07 2013-03-12 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Publications (2)

Publication Number Publication Date
AU2008323848A1 AU2008323848A1 (en) 2009-05-14
AU2008323848B2 true AU2008323848B2 (en) 2014-09-25

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ID=40257038

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008323848A Ceased AU2008323848B2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Country Status (17)

Country Link
US (4) US8236318B2 (cg-RX-API-DMAC7.html)
EP (2) EP2224954B1 (cg-RX-API-DMAC7.html)
JP (3) JP5701606B2 (cg-RX-API-DMAC7.html)
KR (2) KR101811965B1 (cg-RX-API-DMAC7.html)
CN (1) CN101888856B (cg-RX-API-DMAC7.html)
AU (1) AU2008323848B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0820270A2 (cg-RX-API-DMAC7.html)
CA (1) CA2704583A1 (cg-RX-API-DMAC7.html)
DK (1) DK2224954T3 (cg-RX-API-DMAC7.html)
EA (2) EA201692127A1 (cg-RX-API-DMAC7.html)
ES (1) ES2445755T3 (cg-RX-API-DMAC7.html)
IL (1) IL205393A (cg-RX-API-DMAC7.html)
MX (1) MX2010005022A (cg-RX-API-DMAC7.html)
NZ (2) NZ585556A (cg-RX-API-DMAC7.html)
SG (2) SG10201605208QA (cg-RX-API-DMAC7.html)
WO (1) WO2009061996A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201003101B (cg-RX-API-DMAC7.html)

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EP3238739B1 (en) 2008-09-22 2020-10-21 Baylor College of Medicine Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
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