AU2007341937B2 - Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors - Google Patents

Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors Download PDF

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Publication number
AU2007341937B2
AU2007341937B2 AU2007341937A AU2007341937A AU2007341937B2 AU 2007341937 B2 AU2007341937 B2 AU 2007341937B2 AU 2007341937 A AU2007341937 A AU 2007341937A AU 2007341937 A AU2007341937 A AU 2007341937A AU 2007341937 B2 AU2007341937 B2 AU 2007341937B2
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Prior art keywords
optionally substituted
benzo
group
dihydro
heteroaryl
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AU2007341937A
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AU2007341937A1 (en
Inventor
Pingyu Ding
Dane Goff
Thilo Heckrodt
Sacha Holland
Joane Litvak
Rajinder Singh
Jiaxin Yu
Jing Zhang
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Rigel Pharmaceuticals Inc
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Rigel Pharmaceuticals Inc
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
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AU2007341937A 2006-12-29 2007-12-29 Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors Ceased AU2007341937B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US88285006P 2006-12-29 2006-12-29
US60/882,850 2006-12-29
US89540007P 2007-03-16 2007-03-16
US60/895,400 2007-03-16
US97093107P 2007-09-07 2007-09-07
US60/970,931 2007-09-07
PCT/US2007/089177 WO2008083367A2 (en) 2006-12-29 2007-12-29 Polycyclic heteroaryl substituted triazoles useful as axl inhibitors

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AU2007341937A1 AU2007341937A1 (en) 2008-07-10
AU2007341937B2 true AU2007341937B2 (en) 2013-07-11

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AU2007341937A Ceased AU2007341937B2 (en) 2006-12-29 2007-12-29 Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors

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US (5) US7709482B2 (enExample)
EP (1) EP2078010B1 (enExample)
JP (2) JP5546250B2 (enExample)
CN (1) CN101622246B (enExample)
AU (1) AU2007341937B2 (enExample)
CA (1) CA2710234C (enExample)
CY (1) CY1115188T1 (enExample)
DK (1) DK2078010T3 (enExample)
ES (1) ES2460894T3 (enExample)
HR (1) HRP20140378T1 (enExample)
ME (1) ME01832B (enExample)
PL (1) PL2078010T3 (enExample)
PT (1) PT2078010E (enExample)
RS (1) RS53281B (enExample)
SI (1) SI2078010T1 (enExample)
WO (1) WO2008083367A2 (enExample)

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WO2006135993A1 (en) * 2005-06-24 2006-12-28 Gilead Sciences, Inc. Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for treating hepatitis c.
CA2621503C (en) * 2005-09-07 2014-05-20 Rigel Pharmaceuticals, Inc. Triazole derivatives useful as axl inhibitors
US8338435B2 (en) * 2006-07-20 2012-12-25 Gilead Sciences, Inc. Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections
TW200840584A (en) * 2006-12-26 2008-10-16 Gilead Sciences Inc Pyrido(3,2-d)pyrimidines useful for treating viral infections
RS53281B (sr) 2006-12-29 2014-08-29 Rigel Pharmaceuticals Inc. Policiklični heteroaril supstituisani triazoli koji su korisni kao axl inhibitori
CA2710051C (en) 2006-12-29 2017-05-16 Rigel Pharmaceuticals, Inc. Substituted triazoles useful as axl inhibitors
CA2710230C (en) 2006-12-29 2016-02-23 Rigel Pharmaceuticals, Inc. Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
CN101622248B (zh) 2006-12-29 2013-04-17 里格尔制药公司 用作axl抑制剂的n3-杂芳基取代的三唑和n5-杂芳基取代的三唑
ES2406930T3 (es) * 2006-12-29 2013-06-10 Rigel Pharmaceuticals, Inc. Triazoles sustituidos con arilo bicíclico y heteroarilo bicíclico útiles como inhibidores de AXL
CA2704052C (en) * 2007-10-26 2015-04-21 Rigel Pharmaceuticals, Inc. Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as axl inhibitors
HRP20170317T1 (hr) 2008-02-15 2017-04-21 Rigel Pharmaceuticals, Inc. Spojevi pirimidin-2-amina i njihova uporaba kao inhibitora jak kinaza
CA2730251C (en) 2008-07-09 2016-08-09 Rigel Pharmaceuticals, Inc. Bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
CA2730231C (en) 2008-07-09 2016-10-18 Rigel Pharmaceuticals, Inc. Polycyclic heteroaryl substituted triazoles useful as axl inhibitors
JP4644273B2 (ja) * 2008-07-15 2011-03-02 本田技研工業株式会社 車両周辺監視装置
BRPI1007046B1 (pt) 2009-01-16 2019-07-16 Rigel Pharmaceuticals, Inc. Inibidores axl para uso em terapia de combinação para evitar, tratar ou controlar o câncer metastático.
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